Motor recovery and axonal plasticity with short-term amphetamine after stroke

Stroke

Volumn 40, Issue 1, 2009, Pages 294-302

  Papadopoulos, Catherine M ^a,c   Tsai, Shih Yen ^a   Guillen, Veronica ^a   Ortega, Juan ^a   Kartje, Gwendolyn L ^a,b   Wolf, William A ^a,c  

^a HINES VA HOSPITAL   (United States)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Forelimb reaching task; Ladder rung walk test; MCAO; Physical therapy; Rat

Indexed keywords

AMPHETAMINE; AMPHETAMINE DERIVATIVE; CENTRAL STIMULANT AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONVALESCENCE; DRUG MECHANISM; FORELIMB; MALE; MOTOR CORTEX; MOTOR PERFORMANCE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; RAT; STROKE; ANIMAL; CEREBRAL ARTERY DISEASE; DISEASE MODEL; DRUG ADMINISTRATION; DRUG EFFECT; EFFERENT NERVE; GROWTH CONE; INNERVATION; LONG EVANS RAT; METABOLISM; MOTOR DYSFUNCTION; NERVE REGENERATION; PARESIS; PATHOPHYSIOLOGY; PHYSIOLOGY; TREATMENT OUTCOME; ULTRASTRUCTURE;

AMPHETAMINES; ANIMALS; CENTRAL NERVOUS SYSTEM STIMULANTS; DISEASE MODELS, ANIMAL; DRUG ADMINISTRATION SCHEDULE; EFFERENT PATHWAYS; FORELIMB; GROWTH CONES; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MOTOR CORTEX; MOVEMENT DISORDERS; NERVE REGENERATION; NEURONAL PLASTICITY; PARESIS; RATS; RATS, LONG-EVANS; RECOVERY OF FUNCTION; STROKE; TREATMENT OUTCOME;

EID: 60549084896     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/STROKEAHA.108.519769     Document Type: Article

References (68)

1. American Heart Association. Heart Disease and Stroke Statistics-2008 Update. Dallas: American Heart Association.
2. Kuczenski R, Segal DS. Locomotor effects of acute and repeated threshold doses of amphetamine and methylphenidate: relative roles of dopamine and norepinephrine. J Pharmacol Exp Ther. 2001;296: 876-883.
3. Ramic M, Emerick AJ, Bollnow MR, O'Brien TE, Tsai SY, Kartje GL. Axonal plasticity is associated with motor recovery following amphetamine treatment combined with rehabilitation after brain injury in the adult rat. Brain Res. 2006;1111:176-186.
4. Stroemer RP, Kent TA, Hulsebosch CE. Enhanced neocortical neural sprouting, synaptogenesis, and behavioral recovery with D-amphetamine therapy after neocortical infarction in rats. Stroke. 1998;29:2381-2393.
5. Feeney DM, Gonzalez A, Law WA. Amphetamine, haloperidol, and experience interact to affect rate of recovery after motor cortex injury. Science. 1982;217:855-857.
6. Hovda DA, Fenney DM. Amphetamine with experience promotes recovery of locomotor function after unilateral frontal cortex injury in the cat. Brain Res. 1984;298:358-361.
7. Goldstein LB, Davis JN. Influence of lesion size and location on amphetamine-facilitated recovery of beam-walking in rats. Behav Neurosci. 1990;104:320-327.
8. Schmanke TD, Avery RA, Barth ™. The effects of amphetamine on recovery of function after cortical damage in the rat depend on the behavioral requirements of the task. J Neurotrauma. 1996;13:293-307.
9. Adkins DL, Jones TA. D-amphetamine enhances skilled reaching after ischemic cortical lesions in rats. Neurosci Lett. 2005;380:214-218.
10. Gilmour G, Iversen SD, O'Neill MF, O'Neill MJ, Ward MA, Bannerman DM. Amphetamine promotes task-dependent recovery following focal cortical ischaemic lesions in the rat. Behav Brain Res. 2005;165:98-109.
11. Crisostomo EA, Duncan PW, Propst M, Dawson DV, Davis JN. Evidence that amphetamine with physical therapy promotes recovery of motor function in stroke patients. Ann Neurol. 1988;23:94-97.
12. Walker-Batson D, Smith P, Curtis S, Unwin H, Greenlee R. Amphetamine paired with physical therapy accelerates motor recovery after stroke. Further evidence. Stroke. 1995;26:2254-2259.
13. Treig T, Werner C, Sachse M, Hesse S. No benefit from D-amphetamine when added to physiotherapy after stroke: a randomized, placebocontrolled study. Clin Rehabil. 2003;17:590-599.
14. Martinsson L, Hardemark HG, Eksborg S. Should amphetamines be given to improve recovery after stroke? Stroke. 2007;38:2400-2401.
15. Martinsson L, Hardemark H, Eksborg S. Amphetamines for improving recovery after stroke. Cochrane Database Syst Rev. 2007;1:CD002090.
16. Goldstein LB. Amphetamines and related drugs in motor recovery after stroke. Phys Med Rehabil Clin N Am. 2003;14:S125-134.
17. Long D, Young J. Dexamphetamine treatment in stroke. QJM. 2003;96: 673-685.
18. Robinson TE, Kolb B. Alterations in the morphology of dendrites and dendritic spines in the nucleus accumbens and prefrontal cortex following repeated treatment with amphetamine or cocaine. Eur J Neurosci. 1999; 11:1598-1604.
19. Nestler EJ. Molecular basis of long-term plasticity underlying addiction. Nat Rev Neurosci. 2001;2:119-128.
20. Biernaskie J, Corbett D. Enriched rehabilitative training promotes improved forelimb motor function and enhanced dendritic growth after focal ischemic injury. J Neurosci. 2001;21:5272-5280.
21. Johansson BB, Ohlsson AL. Environment, social interaction, and physical activity as determinants of functional outcome after cerebral infarction in the rat. Exp Neurol. 1996;139:322-327.
22. Johansson BB, Belichenko PV. Neuronal plasticity and dendritic spines: effect of environmental enrichment on intact and postischemic rat brain. J Cereb Blood Flow Metab. 2002;22:89-96.
23. Keyvani K, Sachser N, Witte OW, Paulus W. Gene expression profiling in the intact and injured brain following environmental enrichment. J Neuropathol Exp Neurol. 2004;63:598-609.
24. Kuczenski R, Segal DS, Cho AK, Melega W. Hippocampus norepinephrine, caudate dopamine and serotonin, and behavioral responses to the stereoisomers of amphetamine and methamphetamine. J Neurosci. 1995; 15:1308-1317.
25. Papadopoulos CM, Tsai SY, Alsbiei T, O'Brien TE, Schwab ME, Kartje GL. Functional recovery and neuroanatomical plasticity following middle cerebral artery occlusion and IN-1 antibody treatment in the adult rat. Ann Neurol. 2002;51:433-441.
26. Emerick AJ, Kartje GL. Behavioral recovery and anatomical plasticity in adult rats after cortical lesion and treatment with monoclonal antibody IN-1. Behav Brain Res. 2004;152:315-325.
27. Metz GA, Whishaw IQ. Cortical and subcortical lesions impair skilled walking in the ladder rung walking test: a new task to evaluate fore-and hindlimb stepping, placing, and co-ordination. J Neurosci Methods. 2002; 115:169-179.
28. Neafsey EJ, Bold EL, Haas G, Hurley-Gius KM, Quirk G, Sievert CF, Terreberry RR. The organization of the rat motor cortex: a microstimulation mapping study. Brain Res. 1986;396:77-96.
29. Rosenzweig MR, Bennett EL, Hebert M, Morimoto H. Social grouping cannot account for cerebral effects of enriched environments. Brain Res. 1978;153:563-576.
30. Whishaw IQ. Loss of the innate cortical engram for action patterns used in skilled reaching and the development of behavioral compensation following motor cortex lesions in the rat. Neuropharmacology. 2000;39: 788-805.
31. Luke LM, Allred RP, Jones TA. Unilateral ischemic sensorimotor cortical damage induces contralesional synaptogenesis and enhances skilled reaching with the ipsilateral forelimb in adult male rats. Synapse. 2004; 54:187-199.
32. Hsu JE, Jones TA. Contralesional neural plasticity and functional changes in the less-affected forelimb after large and small cortical infarcts in rats. Exp Neurol. 2006;201:479-494.
33. Alaverdashvili M, Lim DH, Whishaw IQ. No improvement by amphetamine on learned non-use, attempts, success or movement in skilled reaching by the rat after motor cortex stroke. Eur J Neurosci. 2007;25:3442-3452.
34. Melega WP, Williams AE, Schmitz DA, DiStefano EW, Cho AK. Phar-macokinetic and pharmacodynamic analysis of the actions of D-amphetamine and D-methamphetamine on the dopamine terminal. J Pharmacol Exp Ther. 1995;274:90-96.
35. Martinsson L, Yang X, Beck O, Wahlgren NG, Eksborg S. Pharmacokinetics of dexamphetamine in acute stroke. Clin Neuropharmacol. 2003; 26:270-276.
36. Park YH, Kantor L, Wang KK, Gnegy ME. Repeated, intermittent treatment with amphetamine induces neurite outgrowth in rat pheochromocytoma cells (PC12 cells). Brain Res. 2002;951:43-52.
37. Baird A. Potential mechanisms regulating the extracellular activities of basic fibroblast growth factor (FGF-2). Mol Reprod Dev. 1994;39:43-48.
38. Patel MN, McNamara JO. Selective enhancement of axonal branching of cultured dentate gyrus neurons by neurotrophic factors. Neuroscience. 1995;69:763-770.
39. Kawamata T, Dietrich WD, Schallert T, Gotts JE, Cocke RR, Benowitz LI, Finklestein SP. Intracisternal basic fibroblast growth factor enhances functional recovery and up-regulates the expression of a molecular marker of neuronal sprouting following focal cerebral infarction. Proc Natl Acad Sci U S A. 1997;94:8179-8184.
40. Kawamata T, Speliotes EK, Finklestein SP. The role of polypeptide growth factors in recovery from stroke. Adv Neurol. 1997;73:377-382.
41. Kawamoto Y, Nakamura S, Kawamata T, Akiguchi I, Kimura J. Cellular localization of brain-derived neurotrophic factor-like immunoreactivity in adult monkey brain. Brain Res. 1999;821:341-349.
42. Rowntree S, Kolb B. Blockade of basic fibroblast growth factor retards recovery from motor cortex injury in rats. Eur J Neurosci. 1997;9: 2432-2441.
43. Takami K, Iwane M, Kiyota Y, Miyamoto M, Tsukuda R, Shiosaka S. Increase of basic fibroblast growth factor immunoreactivity and its mRNA level in rat brain following transient forebrain ischemia. Exp Brain Res. 1992;90:1-10.
44. Reilly JF, Kumari VG. Alterations in fibroblast growth factor receptor expression following brain injury. Exp Neurol. 1996;140:139-150.
45. Chadi G, Tinner B, Agnati LF, Fuxe K. Basic fibroblast growth factor (bFGF, FGF-2) immunoreactivity exists in the noradrenaline, adrenaline and 5-HT nerve cells of the rat brain. Neurosci Lett. 1993;160:171-176.
46. Wei OY, Huang YL, Da CD, Cheng JS. Alteration of basic fibroblast growth factor expression in rat during cerebral ischemia. Acta Pharmacol Sin. 2000;21:296-300.
47. Flores C, Rodaros D, Stewart J. Long-lasting induction of astrocytic basic fibroblast growth factor by repeated injections of amphetamine: blockade by concurrent treatment with a glutamate antagonist. J Neurosci. 1998; 18:9547-9555.
48. Flores C, Samaha AN, Stewart J. Requirement of endogenous basic fibroblast growth factor for sensitization to amphetamine. J Neurosci. 2000;20:RC55.
49. Goldstein LB, Bullman S. Effects of dorsal noradrenergic bundle lesions on recovery after sensorimotor cortex injury. Pharmacol Biochem Behav. 1997;58:1151-1157.
50. Feeney DM, De Smet AM, Rai S. Noradrenergic modulation of hemi-plegia: facilitation and maintenance of recovery. Restor Neurol Neurosci. 2004;22:175-190.
51. Goldstein LB. Neurotransmitters and motor activity: effects on functional recovery after brain injury. NeuroRx. 2006;3:451-457.
52. Whishaw IQ, Alaverdashvili M, Kolb B. The problem of relating plasticity and skilled reaching after motor cortex stroke in the rat. Behav Brain Res. 2008;192:124-136.
53. Kolb B, Gibb R, van der KD. Cortical and striatal structure and connectivity are altered by neonatal hemidecortication in rats. J Comp Neurol. 1992;322:311-324.
54. Yu XH, Moret V, Rouiller EM. Re-examination of the plasticity of the corticothalamic projection after unilateral neonatal lesion of the senso- rimotor cortex in the rat: a phaseolus vulgaris-leucoagglutinin tracing study. J Hirnforsch. 1995;36:123-133.
55. Nah SH, Leong SK. Bilateral corticofugal projection to the red nucleus after neonatal lesions in the albino rat. Brain Res. 1976;107:433-436.
56. Naus C, Flumerfelt BA, Hrycyshyn AW. An anterograde HRP-WGA study of aberrant corticorubral projections following neonatal lesions of the rat sensorimotor cortex. Exp Brain Res. 1985;59:365-371.
57. Castro AJ, Mihailoff GA. Corticopontine remodelling after cortical and/or cerebellar lesions in newborn rats. J Comp Neurol. 1983;219: 112-123.
58. Kartje-Tillotson G, Neafsey EJ, Castro AJ. Topography of corticopontine remodelling after cortical lesions in newborn rats. J Comp Neurol. 1986; 250:206-214.
59. Kartje-Tillotson G, Neafsey EJ, Castro AJ. Electrophysiological analysis of motor cortical plasticity after cortical lesions in newborn rats. Brain Res. 1985;332:103-111.
60. Rouiller EM, Liang FY, Moret V, Wiesendanger M. Trajectory of redirected corticospinal axons after unilateral lesion of the sensorimotor cortex in neonatal rat; a phaseolus vulgaris-leucoagglutinin (PHA-L) tracing study. Exp Neurol. 1991;114:53-65.
61. Goldberger ME. Mechanisms contributing to sparing of function following neonatal damage to spinal pathways. Neurochem Pathol. 1986;5: 289-307.
62. Kartje-Tillotson G, O'Donoghue DL, Dauzvardis MF, Castro AJ. Pyramidotomy abolishes the abnormal movements evoked by intracortical microstimulation in adult rats that sustained neonatal cortical lesions. Brain Res. 1987;415:172-177.
63. Kolb B, Whishaw IQ. Plasticity in the neocortex: mechanisms underlying recovery from early brain damage. Prog Neurobiol. 1989;32:235-276.
64. Seymour AB, Andrews EM, Tsai SY, Markus ™, Bollnow MR, Brenneman MM, O'Brien TE, Castro AJ, Schwab ME, Kartje GL. Delayed treatment with monoclonal antibody IN-1 1 week after stroke results in recovery of function and corticorubral plasticity in adult rats. J Cereb Blood Flow Metab. 2005;25:1366-1375.
65. Schaechter JD. Motor rehabilitation and brain plasticity after hemiparetic stroke. Prog Neurobiol. 2004;73:61-72.
66. Darian-Smith C, Gilbert CD. Topographic reorganization in the striate cortex of the adult cat and monkey is cortically mediated. J Neurosci. 1995;15:1631-1647.
67. Schwab ME, Bartholdi D. Degeneration and regeneration of axons in the lesioned spinal cord. Physiol Rev. 1996;76:319-370.
68. Schallert T, Leasure JL, Kolb B. Experience-associated structural events, subependymal cellular proliferative activity, and functional recovery after injury to the central nervous system. J Cereb Blood Flow Metab. 2000; 20:1513-1528.