A single bout of whole-body resistance exercise augments basal VLDL-triacylglycerol removal from plasma in healthy untrained men

Clinical Science

Volumn 116, Issue 2, 2009, Pages 147-156

  Tsekouras, Yiannis E ^a   Magkos, Faidon ^a   Prentzas, Konstantinos I ^a   Basioukas, Konstantinos N ^a   Matsama, Stergoula G ^a   Yanni, Amalia E ^a   Kavouras, Stavros A ^a   Sidossis, Labros S ^a  

^a HAROKOPIO UNIVERSITY   (Greece)

Author keywords

Acute exercise; Hepatic metabolism; Lipid kinetics; Triacylglycerol; Very low density lipoprotein (VLDL)

Indexed keywords

3 HYDROXYBUTYRIC ACID; FATTY ACID; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN; VERY LOW DENSITY LIPOPROTEIN TRIGLYCERIDE;

ADULT; ARTICLE; BODY COMPOSITION; CHOLESTEROL BLOOD LEVEL; CLEARANCE; CLINICAL TRIAL; DIETARY INTAKE; DYNAMOMETRY; ENERGY EXPENDITURE; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN EXPERIMENT; INSULIN BLOOD LEVEL; ISOKINETIC EXERCISE; LIPID METABOLISM; MALE; METABOLIC RATE; NORMAL HUMAN; OXIDATION; PRIORITY JOURNAL; SECRETION; TRIACYLGLYCEROL BLOOD LEVEL; WHOLE BODY ISOKINETIC RESISTANCE EXERCISE; BASAL METABOLIC RATE; BLOOD; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET; DIET RESTRICTION; ENERGY METABOLISM; EXERCISE; EXERCISE TEST; METHODOLOGY; OXYGEN CONSUMPTION; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL;

ADULT; BASAL METABOLISM; BODY COMPOSITION; DIET; ENERGY METABOLISM; EXERCISE; EXERCISE TEST; FASTING; HUMANS; INSULIN; LIPOPROTEINS, VLDL; MALE; OXYGEN CONSUMPTION; TRIGLYCERIDES; YOUNG ADULT;

EID: 60549084542     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20080078     Document Type: Article

References (53)

1. Hokanson, J. E. and Austin, M. A. (1996) Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: a meta-analysis of population-based prospective studies. J. Cardiovasc. Risk 3, 213-219
2. Boberg, J., Carlson, L. A., Freyschuss, U., Lassers, B. W. and Wahlqvist, M. L. (1972) Splanchnic secretion rates of plasma triglycerides and total and splanchnic turnover of plasma free fatty acids in men with normo- and hypertriglyceridaemia. Eur. J. Clin. Invest. 2, 454-466
3. Reaven, G. M., Hill, D. B., Gross, R. C. and Farquhar, J. W. (1965) Kinetics of triglyceride turnover of very low density lipoproteins of human plasma. J. Clin. Invest. 44, 1826-1833
4. Magkos, F., Wright, D. C., Patterson, B. W., Mohammed, B. S. and Mittendorfer, B. (2006) Lipid metabolism response to a single, prolonged bout of endurance exercise in healthy young men. Am. J. Physiol. Endocrinol. Metab. 290, E355-E362
5. Tsekouras, Y. E., Yanni, A. E., Bougatsas, D., Kavouras, S. A. and Sidossis, L. S. (2007) A single bout of brisk walking increases basal very low-density lipoprotein triacylglycerol clearance in young men. Metab. Clin. Exp. 56, 1037-1043
6. Fisher, R. M., Coppack, S. W., Humphreys, S. M., Gibbons, G. F. and Frayn, K. N. (1995) Human triacylglycerol-rich lipoprotein subfractions as substrates for lipoprotein lipase. Clin. Chim. Acta 236, 7-17
7. Streja, D. A. (1979) Triglyceride removal from very low density lipoproteins in vivo as a function of their triglyceride content. Atherosclerosis 32, 57-67
8. Seip, R. L. and Semenkovich, C. F. (1998) Skeletal muscle lipoprotein lipase: molecular regulation and physiological effects in relation to exercise. Exercise Sport Sci. Rev. 26, 191-218
9. Kiens, B. and Lithell, H. (1989) Lipoprotein metabolism influenced by training-induced changes in human skeletal muscle. J. Clin. Invest. 83, 558-564
10. Malkova, D., Evans, R. D., Frayn, K. N., Humphreys, S. M., Jones, P. R. and Hardman, A. E. (2000) Prior exercise and postprandial substrate extraction across the human leg. Am. J. Physiol. Endocrinol. Metab. 279, E1020-E1028
11. Cullinane, E., Siconolfi, S., Saritelli, A. and Thompson, P. D. (1982) Acute decrease in serum triglycerides with exercise: is there a threshold for an exercise effect? Metab. Clin. Exp. 31, 844-847
12. Annuzzi, G., Jansson, E., Kaijser, L., Holmquist, L. and Carlson, L. A. (1987) Increased removal rate of exogenous triglycerides after prolonged exercise in man: time course and effect of exercise duration. Metab. Clin. Exp. 36, 438-443
13. Tsetsonis, N. V. and Hardman, A. E. (1996) Effects of low and moderate intensity treadmill walking on postprandial lipaemia in healthy young adults. Eur. J. Appl. Physiol. Occup. Physiol. 73, 419-426
14. Tsetsonis, N. V. and Hardman, A. E. (1996) Reduction in postprandial lipemia after walking: influence of exercise intensity. Med. Sci. Sports Exercise 28, 1235-1242
15. Petitt, D. S., Arngrimsson, S. A. and Cureton, K. J. (2003) Effect of resistance exercise on postprandial lipemia. J. Appl. Physiol. 94, 694-700
16. Burns, S. F., Corrie, H., Holder, E., Nightingale, T. and Stensel, D. J. (2005) A single session of resistance exercise does not reduce postprandial lipaemia. J. Sports Sci. 23, 251-260
17. Shannon, K. A., Shannon, R. M., Clore, J. N., Gennings, C., Warren, B. J. and Potteiger, J. A. (2005) Resistance exercise and postprandial lipemia: the dose effect of differing volumes of acute resistance exercise bouts. Metab. Clin. Exp. 54, 756-763
18. Zafeiridis, A., Goloi, E., Petridou, A., Dipla, K., Mougios, V. and Kellis, S. (2007) Effects of low- and high-volume resistance exercise on postprandial lipaemia. Br. J. Nutr. 97, 471-477
19. Burns, S. F., Broom, D. R., Miyashita, M., Ueda, C. and Stensel, D. J. (2006) Increased postprandial triacylglycerol concentrations following resistance exercise. Med. Sci. Sports Exercise 38, 527-533
20. De Lorenzo, A., Andreoli, A. and Candeloro, N. (1997) Within subject variability in body composition using dual energy X-ray absorptiometry. Clin. Physiol. 17, 383-388
21. American College of Sports Medicine (2000) ACSM's Guidelines for Exercise Testing and Prescription, 6 edn, Lippincott Williams & Wilkins, Philadelphia, PA
22. Weir, J. B. (1949) New methods for calculating metabolic rate with special reference to protein metabolism. J. Physiol. 109, 1-9
23. Frayn, K. N. (1983) Calculation of substrate oxidation rates in vivo from gaseous exchange. J. Appl. Physiol. 55, 628-634
24. Friedewald, W. T., Levy, R. I. and Fredrickson, D. S. (1972) Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin. Chem. 18, 499-502
25. Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F. and Turner, R. C. (1985) Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28, 412-419
26. Dill, D. B. and Costill, D. L. (1974) Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration. J. Appl. Physiol. 37, 247-248
27. Patterson, B. W., Mittendorfer, B., Elias, N., Satyanarayana, R. and Klein, S. (2002) Use of stable isotopically labeled tracers to measure very low density lipoprotein-triglyceride turnover. J. Lipid Res. 43, 223-233
28. 5] glycerol bolus to measure very low density lipoprotein triglyceride kinetics in humans. J. Lipid Res. 40, 2111-2117
29. Boer, P. (1984) Estimated lean body mass as an index for normalization of body fluid volumes in humans. Am. J. Physiol. 247, F632-F636
30. Reichl, D. (1990) Lipoproteins of human peripheral lymph. Eur. Heart J. 11 (Suppl. E), 230-236
31. Magkos, F., Patterson, B. W. and Mittendorfer, B. (2007) Reproducibility of stable isotope-labeled tracer measures of VLDL-triglyceride and VLDL-apolipoprotein B-100 kinetics. J. Lipid Res. 48, 1204-1211
32. Holloszy, J. O., Skinner, J. S., Toro, G. and Cureton, T. K. (1964) Effects of a six month program of endurance exercise on the serum lipids of middle-aged men. Am. J. Cardiol. 14, 753-760
33. Durstine, J. L., Grandjean, P. W., Cox, C. A. and Thompson, P. D. (2002) Lipids, lipoproteins, and exercise. J. Cardiopulm. Rehabil. 22, 385-398
34. Thompson, P. D., Crouse, S. F., Goodpaster, B., Kelley, D., Moyna, N. and Pescatello, L. (2001) The acute versus the chronic response to exercise. Med. Sci. Sports Exercise 33, S438-S445
35. Hurley, B. F. and Kokkinos, P. F. (1987) Effects of weight training on risk factors for coronary artery disease. Sports Med. 4, 231-238
36. Burton, F. L., Malkova, D., Caslake M. J. and Gill, J. M. (2008) Energy replacement attenuates the effects of prior moderate exercise on postprandial metabolism in overweight/obese men. Int. J. Obes. 32, 481-489
37. Magkos, F., Patterson, B. W., Mohammed, B. S., Klein, S. and Mittendorfer, B. (2007) Women produce fewer but triglyceride-richer very low-density lipoproteins than men. J. Clin. Endocrinol. Metab. 92, 1311-1318
38. Streja, D., Kallai, M. A. and Steiner, G. (1977) The metabolic heterogeneity of human very low density lipoprotein triglyceride. Metab. Clin. Exp. 26, 1333-1344
39. Verschoor, L., Chen, Y. D., Reaven, E. P. and Reaven, G. M. (1985) Glucose and fructose feeding lead to alterations in structure and function of very low density lipoproteins. Horm. Metab. Res. 17, 285-288
40. Seip, R. L., Angelopoulos, T. J. and Semenkovich, C. F. (1995) Exercise induces human lipoprotein lipase gene expression in skeletal muscle but not adipose tissue. Am. J. Physiol. 268, E229-E236
41. Seip, R. L., Mair, K., Cole, T. G. and Semenkovich, C. F. (1997) Induction of human skeletal muscle lipoprotein lipase gene expression by short-term exercise is transient. Am. J. Physiol. 272, E255-E261
42. Kiens, B., Lithell, H., Mikines, K. J. and Richter, E. A. (1989) Effects of insulin and exercise on muscle lipoprotein lipase activity in man and its relation to insulin action. J. Clin. Invest. 84, 1124-1129
43. Kiens, B, and Richter, E. A. (1998) Utilization of skeletal muscle triacylglycerol during postexercise recovery in humans. Am. J. Physiol. 275, E332-E337
44. Lamarche, B., Uffelman, K. D., Carpentier, A. et al. (1999) Triglyceride enrichment of HDL enhances in vivo metabolic clearance of HDL apo A-I in healthy men. J. Clin. Invest. 103, 1191-1199
45. Foger, B., Wohlfarter, T., Ritsch, A. et al. (1994) Kinetics of lipids, apolipoproteins, and cholesteryl ester transfer protein in plasma after a bicycle marathon. Metab. Clin. Exp. 43, 633-639
46. Magkos, F., Patterson, B. W., Mohammed, B. S. and Mittendorfer, B. (2007) A single 1-h bout of evening exercise increases basal FFA flux without affecting VLDL-triglyceride and VLDL-apolipoprotein B-100 kinetics in untrained lean men. Am. J. Physiol. Endocrinol. Metab. 292, E1568-E1574
47. Lewis, G. F. (1997) Fatty acid regulation of very low density lipoprotein production. Curr. Opin. Lipidol. 8, 146-153
48. Gibbons, G. F., Brown, A. M., Wiggins, D. and Pease, R. (2002) The roles of insulin and fatty acids in the regulation of hepatic very-low-density lipoprotein assembly. J. R. Soc. Med. 95 (Suppl. 42), 23-32
49. Carpentier, A., Patterson, B. W., Leung, N. and Lewis, G. F. (2002) Sensitivity to acute insulin-mediated suppression of plasma free fatty acids is not a determinant of fasting VLDL triglyceride secretion in healthy humans. Diabetes 51, 1867-1875
50. Gormsen, L. C., Jensen, M. D., Schmitz, O., Moller, N., Christiansen, J. S. and Nielsen, S. (2006) Energy expenditure, insulin, and VLDL-triglyceride production in humans. J. Lipid Res. 47, 2325-2332
51. Koopman, R., Manders, R. J., Jonkers, R. A., Hul, G. B., Kuipers, H. and van Loon, L. J. (2006) Intramyocellular lipid and glycogen content are reduced following resistance exercise in untrained healthy males. Eur. J. Appl. Physiol. 96, 525-534
52. Jamurtas, A. Z., Koutedakis, Y., Paschalis, V. et al. (2004) The effects of a single bout of exercise on resting energy expenditure and respiratory exchange ratio. Eur.J. Appl. Physiol. 92, 393-398
53. Herd, S. L., Kiens, B., Boobis, L. H. and Hardman, A. E. (2001) Moderate exercise, postprandial lipemia, and skeletal muscle lipoprotein lipase activity. Metab. Clin. Exp. 50, 756-762