Design and synthesis of calpain inhibitory 6-pyridone 2-carboxamide derivatives

European Journal of Medicinal Chemistry

Volumn 44, Issue 3, 2009, Pages 1331-1334

  Lee, Ki Yong ^a   Seob Lee, Kwang ^b   Jin, Changbae ^b   Lee, Yong Sup ^a  

^a Kyung Hee University   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

Author keywords

6 Pyridone; Calpain inhibitor; Conformational restriction; Stroke

Indexed keywords

6 PYRIDONE 2 CARBOXAMIDE DERIVATIVE; [1 [(1 FORMYL 2 PHENYLETHYL)CARBAMOYL] 2 METHYLPROPYL]CARBAMIC ACID BENZYL ESTER; CALPAIN 1; CYSTEINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG CONFORMATION; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; IC 50;

CALPAIN; CYSTEINE PROTEINASE INHIBITORS; DRUG DESIGN; PYRIDONES;

EID: 60549083136     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.02.023     Document Type: Article

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