Synthesis and calpain inhibitory activity of α-ketoamides with 2,3-methanoleucine stereoisomers at the P2 position

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 22, 2000, Pages 2497-2500

  Donkor, Isaac O ^a   Zheng, Xiaozhang ^a   Miller, Duane D ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3 METHANOLEUCINE; ALPHA KETOAMIDE; AMIDE; CALPASTATIN; CATHEPSIN B; CATHEPSIN L; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM CELL LEVEL; CHEMICAL REACTION; ENZYME ACTIVE SITE; ENZYME INHIBITION; PROTEIN DEGRADATION; STEREOCHEMISTRY; STEREOISOMERISM; SYNTHESIS; THROMBOCYTE AGGREGATION;

EID: 0034694353     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00518-7     Document Type: Article

References (15)

1. The graphical determination of K(m) and K(i)