(2-Aryl-5-methylimidazol-4-ylcarbonyl)guanidines and (2-aryl-5-methyloxazol-4-ylcarbonyl)guanidines as NHE-1 inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 5, 2009, Pages 1329-1331

  Lee, Sunkyung ^a   Yi, Kyu Yang ^a   Youn, Sung Jun ^a   Lee, Byung Ho ^a   Yoo, Sung eun ^a  

^a Korea Research Institute of Chemical Technology   (South Korea)

Author keywords

(2 Aryl 5 methylimidazol 5 ylcarbonyl)guanidine; Cardioprotective; Sodium hydrogen exchanger

Indexed keywords

BENZENE DERIVATIVE; FURAN DERIVATIVE; GUANIDINE DERIVATIVE; IMIDAZOLE DERIVATIVE; OXAZOLE DERIVATIVE; PROTEIN INHIBITOR; SODIUM PROTON EXCHANGE PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HEART INFARCTION; HEART PROTECTION; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION;

ANIMALS; CARDIOTONIC AGENTS; CATION TRANSPORT PROTEINS; GUANIDINES; HUMANS; IMIDAZOLES; MYOCARDIAL INFARCTION; RATS; SODIUM-HYDROGEN ANTIPORTER;

EID: 60449119102     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.01.060     Document Type: Article

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