Involvement of ERK phosphorylation in brainstem neurons in modulation of swallowing reflex in rats

Journal of Physiology

Volumn 587, Issue 4, 2009, Pages 805-817

  Tsujimura, Takanori ^a   Kondo, Masahiro ^a   Kitagawa, Junichi ^a   Tsuboi, Yoshiyuki ^a   Saito, Kimiko ^a   Tohara, Haruka ^a   Ueda, Koichiro ^a   Sessle, Barry J ^b   Iwata, Koichi ^a  

^a NIHON UNIVERSITY   (Japan)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; BICUCULLINE; CAPSAICIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MUSCIMOL; WATER; DISTILLED WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN STEM; CONTROLLED STUDY; ELECTROMYOGRAPHY; ENZYME PHOSPHORYLATION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MICROINJECTION; NERVE CELL; NERVE CELL STIMULATION; NONHUMAN; PRIORITY JOURNAL; RAT; SOLITARY TRACT NUCLEUS; SWALLOWING; TONGUE; TRIGEMINAL NUCLEUS; VIBRISSA; ANIMAL CELL; BRAIN STEM INJURY; FACE MUSCLE; FACE PAIN; NEUROMODULATION; NOCICEPTIVE STIMULATION; SKELETAL MUSCLE; SKIN MUSCLE; TONGUE MUSCLE;

ANIMALS; BRAIN STEM; DEGLUTITION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; MALE; NEURONS; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; REFLEX;

EID: 60449113697     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2008.165324     Document Type: Article

References (63)

1. Amirali A, Tsai G, Schrader N, Weisz D & Sanders I (2001). Mapping of brain stem neuronal circuitry active during swallowing. Ann Otol Rhinol Laryngol 110, 502-513.
2. Barraco R, el-Ridi M, Ergene E, Parizon M & Bradley D (1992). An atlas of the rat subpostremal nucleus tractus solitarius. Brain Res Bull 29, 703-765.
3. Boscan P, Pickering AE & Paton JF (2002). The nucleus of the solitary tract: An integrating station for nociceptive and cardiorespiratory afferents. Exp Physiol 87, 259-266.
4. Buchholz DW (1994). Neurogenic dysphagia: What is the cause when the cause is not obvious? Dysphagia 9, 245-255.
5. Cadden SW (2007). Modulation of human jaw reflexes: Heterotopic stimuli and stress. Arch Oral Biol 52, 370-373.
6. Cairns BE, Sessle BJ & Hu JW (1998). Evidence that excitatory amino acid receptors within the temporomandibular joint region are involved in the reflex activation of the jaw muscles. J Neurosci 18, 8056-8064.
7. Cairns BE, Sessle BJ & Hu JW (2001). Temporomandibular- evoked jaw muscle reflex: Role of brain stem NMDA and non-NMDA receptors. Neuroreport 12, 1875-1878.
8. Caous CA, de Sousa Buck H & Lindsey CJ (2001). Neuronal connections of the paratrigeminal nucleus. A topographic analysis of neurons projecting to bulbar, pontine and thalamic nuclei related to cardiovascular, respiratory and sensory functions. Auton Neurosci 94, 14-24.
9. Chattipakorn S, Chattipakorn N, Light AR, Narhi M & Maixner W (2005). Comparison of Fos expression within the ferret's spinal trigeminal nuclear complex evoked by electrical or noxious-thermal pulpal stimulation. J Pain 6, 569-580.
10. Cruccu G, Agostino R, Lahuerta J & Manfredi M (1986). Inhibition of jaw-closing muscles by electrical stimulation of the ophthalmic division in man. Brain Res 371, 298-304.
11. 2 laser stimulation of the perioral region in man. Exp Brain Res 118, 564-568.
12. Cruz CD, Avelino A, McMahon SB & Cruz F (2005 a). Increased spinal cord phosphorylation of extracellular signal-regulated kinases mediates micturition overactivity in rats with chronic bladder inflammation. Eur J Neurosci 21, 773-781.
13. Cruz CD, Neto FL, Castro-Lopes J, McMahon SB & Cruz F (2005 b). Inhibition of ERK phosphorylation decreases nociceptive behaviour in monoarthritic rats. Pain 116, 411-419.
14. A/Bz receptor subtypes as targets for selective drugs. Curr Med Chem 14, 2680-2701.
15. de Sousa Buck H, Caous CA & Lindsey CJ (2001). Projections of the paratrigeminal nucleus to the ambiguus, rostroventrolateral and lateral reticular nuclei, and the solitary tract. Auton Neurosci 87, 187-200.
16. Doty RW, Richmond WH & Storey AT (1967). Effect of medullary lesions on coordination of deglutition. Exp Neurol 17, 91-106.
17. Dubner R (1978). Neurophysiology of pain. Dent Clin North Am 22, 11-30.
18. Dubner R, Sessle BJ & Storey AT (1978). The Neural Basis of Oral and Facial Function. Plenum Press, New York.
19. Ertekin C, Secil Y, Yuceyar N & Aydogdu I (2004). Oropharyngeal dysphagia in polymyositis/dermatomyositis. Clin Neurol Neurosurg 107, 32-37.
20. Feldman PD & Felder RB (1989). α-Adrenergic influences on neuronal responses to visceral afferent input in the nucleus tractus solitarius. Neuropharmacology 28, 1081-1087.
21. Fukui T, Dai Y, Iwata K, Kamo H, Yamanaka H, Obata K, Kobayashi K, Wang S, Cui X, Yoshiya S & Noguchi K (2007). Frequency-dependent ERK phosphorylation in spinal neurons by electric stimulation of the sciatic nerve and the role in electrophysiological activity. Mol Pain 3, 18.
22. Handwerker HO, Forster C & Kirchhoff C (1991). Discharge patterns of human C-fibers induced by itching and burning stimuli. J Neurophysiol 66, 307-315.
23. Hockman CH, Weerasuriya A & Bieger D (1996). GABA receptor-mediated inhibition of reflex deglutition in the cat. Dysphagia 11, 209-215.
24. Imbe H, Dubner R & Ren K (1999). Masseteric inflammation- induced Fos protein expression in the trigeminal interpolaris/caudalis transition zone: Contribution of somatosensory-vagal-adrenal integration. Brain Res 845, 165-175.
25. Imbe H & Ren K (2000). The up-regulation of preprodynorphin mRNA in trigeminoparabrachial neurons after inflammation. Neuroreport 11, 845-847.
26. Jean A (2001). Brain stem control of swallowing: Neuronal network and cellular mechanisms. Physiol Rev 81, 929-969.
27. Ji RR, Baba H, Brenner GJ & Woolf CJ (1999). Nociceptive- specific activation of ERK in spinal neurons contributes to pain hypersensitivity. Nat Neurosci 2, 1114-1119.
28. Jorgensen EM (2005). GABA. WormBook, 1-13.
29. Kajii Y, Shingai T, Kitagawa J, Takahashi Y, Taguchi Y, Noda T & Yamada Y (2002). Sour taste stimulation facilitates reflex swallowing from the pharynx and larynx in the rat. Physiol Behav 77, 321-325.
30. Katz DM & Karten HJ (1983). Visceral representation within the nucleus of the tractus solitarius in the pigeon, Columba livia. J Comp Neurol 218, 42-73.
31. Kawasaki Y, Kohno T, Zhuang ZY, Brenner GJ, Wang H, Van Der Meer C, Befort K, Woolf CJ & Ji RR (2004). Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization. J Neurosci 24, 8310-8321.
32. Kessler JP & Jean A (1985). Identification of the medullary swallowing regions in the rat. Exp Brain Res 57, 256-263.
33. Kitagawa J, Shingai T, Takahashi Y & Yamada Y (2002). Pharyngeal branch of the glossopharyngeal nerve plays a major role in reflex swallowing from the pharynx. Am J Physiol Regul Integr Comp Physiol 282, R1342-R1347.
34. Kronenberger MB & Meyers AD (1994). Dysphagia following head and neck cancer surgery. Dysphagia 9, 236-244.
35. Lam DK, Sessle BJ, Cairns BE & Hu JW (2005). Peripheral NMDA receptor modulation of jaw muscle electromyographic activity induced by capsaicin injection into the temporomandibular joint of rats. Brain Res 1046, 68-76.
36. B receptor agonists on swallowing in the dog. Eur J Pharmacol 448, 67-70.
37. Li YQ, Takada M & Mizuno N (1993). Identification of premotor interneurons which project bilaterally to the trigeminal motor, facial or hypoglossal nuclei: A fluorescent retrograde double-labeling study in the rat. Brain Res 611, 160-164.
38. Luo P, Zhang J, Yang R & Pendlebury W (2006). Neuronal circuitry and synaptic organization of trigeminal proprioceptive afferents mediating tongue movement and jaw-tongue coordination via hypoglossal premotor neurons. Eur J Neurosci 23, 3269-3283.
39. McConnel FM & O'Connor A (1994). Dysphagia secondary to head and neck cancer surgery. Acta Otorhinolaryngol Belg 48, 165-170.
40. McGrath PA, Sharav Y, Dubner R & Gracely RH (1981). Masseter inhibitory periods and sensations evoked by electrical tooth pulp stimulation. Pain 10, 1-17.
41. Meng ID, Hu JW & Bereiter DA (2000). Parabrachial area and nucleus raphe magnus inhibition of corneal units in rostral and caudal portions of trigeminal subnucleus caudalis in the rat. Pain 87, 241-251.
42. Noma N, Tsuboi Y, Kondo M, Matsumoto M, Sessle BJ, Kitagawa J, Saito K & Iwata K (2008). Organization of pERK-immunoreactive cells in trigeminal spinal nucleus caudalis and upper cervical cord following capsaicin injection into oral and craniofacial regions in rats. J Comp Neurol 507, 1428-1440.
43. Paterson WG (1996). Dysphagia in the elderly. Can Fam Physician 42, 925-932.
44. Paxinos G & Watson C (1998). The Rat Brain in Stereotaxic Coordinates, 4th edn. Academic Press, San Diego.
45. Robbins J & Levine R (1993). Swallowing after lateral medullary syndrome plus. Clin Commun Disord 3, 45-55.
46. Schmidt R, Schmelz M, Forster C, Ringkamp M, Torebjork E & Handwerker H (1995). Novel classes of responsive and unresponsive C nociceptors in human skin. J Neurosci 15, 333-341.
47. Schwartzbaum JS & DiLorenzo PM (1982). Gustatory functions of the nucleus tractus solitarius in the rabbit. Brain Res Bull 8, 285-292.
48. Scott TR, Yaxley S, Sienkiewicz ZJ & Rolls ET (1986). Gustatory responses in the nucleus tractus solitarius of the alert cynomolgus monkey. J Neurophysiol 55, 182-200.
49. Shimizu K, Asano M, Kitagawa J, Ogiso B, Ren K, Oki H, Matsumoto M & Iwata K (2006). Phosphorylation of extracellular signal-regulated kinase in medullary and upper cervical cord neurons following noxious tooth pulp stimulation. Brain Res 1072, 99-109.
50. Sumi T (1970). Changes of hypoglossal nerve activity during inhibition of chewing and swallowing by lingual nerve stimulation. Pflugers Arch 317, 303-309.
51. Szolcsanyi J, Anton F, Reeh PW & Handwerker HO (1988). Selective excitation by capsaicin of mechano-heat sensitive nociceptors in rat skin. Brain Res 446, 262-268.
52. Takeda M, Tanimoto T, Ito M, Nasu M & Matsumoto S (2005). Role of capsaicin-sensitive primary afferent inputs from the masseter muscle in the C1 spinal neurons responding to tooth-pulp stimulation in rats. Exp Brain Res 160, 107-117.
53. Takemura M, Tsujio A, Iwase K, Shimada T & Shigenaga Y (1998). Central terminals of orofacial primary afferents and NADPH-diaphorase activity in the trigemino-solitary complex of rats. Brain Res 781, 77-89.
54. Takemura M, Wakisaka S, Iwase K, Yabuta NH, Nakagawa S, Chen K, Bae YC, Yoshida A & Shigenaga Y (1996). NADPH-diaphorase in the developing rat: Lower brainstem and cervical spinal cord, with special reference to the trigemino-solitary complex. J Comp Neurol 365, 511-525.
55. Travers JB & Smith DV (1979). Gustatory sensitivities in neurons of the hamster nucleus tractus solitarius. Sens Processes 3, 1-26.
56. Tsai CM, Chiang CY, Yu XM & Sessle BJ (1999). Involvement of trigeminal subnucleus caudalis (medullary dorsal horn) in craniofacial nociceptive reflex activity. Pain 81, 115-128.
57. Vaiman M, Nahlieli O & Eliav E (2006). Oynophagia in patients after dental extraction: Surface electromyography study. Head Face Med 2, 34.
58. Wang YT & Bieger D (1991). Role of solitarial GABAergic mechanisms in control of swallowing. Am J Physiol Regul Integr Comp Physiol 261, R639-R646.
59. Xu Z, Wang BR, Ding YQ, Kuang F, Wang X, Duan XL, Jiao XY & Ju G (2002). Extracellular signal-regulated kinases1/2 in neurons of the dorsal motor nucleus of the vagus nerve and nucleus of the solitary tract are activated by noxious visceral stimulus in mice. Neurosci Lett 334, 103-106.
60. Zec N & Kinney HC (2003). Anatomic relationships of the human nucleus of the solitary tract in the medulla oblongata: A DiI labeling study. Auton Neurosci 105, 131-144.
61. Zhuang ZY, Gerner P, Woolf CJ & Ji RR (2005). ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model. Pain 114, 149-159.
62. Zimmermann M (1983). Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16, 109-110.
63. Zoungrana OR, Lamkadem M, Amri M, Car A & Roman C (2000). Effects of lingual nerve afferents on swallowing in sheep. Exp Brain Res 132, 500-509.