Anatomic relationships of the human nucleus of the solitary tract in the medulla oblongata: A DiI labeling study

Autonomic Neuroscience: Basic and Clinical

Volumn 105, Issue 2, 2003, Pages 131-144

  Zec, Natasa ^a   Kinney, Hannah C ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Arcuate nucleus of the medulla oblongata; Autonomic control; Cardiovascular reflexes; Caudal raphe; Chemoreception; Nucleus of the solitary tract; Respiratory control; Serotonin; Sudden infant death

Indexed keywords

1,1' DIOCTADECYL 3,3,3',3' TETRAMETHYLINDOCARBOCYANINE;

ARTICLE; AUTONOMIC NERVOUS SYSTEM; CARDIOPULMONARY HEMODYNAMICS; CELL LABELING; CHEMORECEPTOR; CHEMOSENSITIVITY; CONTROLLED STUDY; FETUS; FLUORESCENCE; HUMAN; HUMAN TISSUE; MEDULLA OBLONGATA; PERINATAL DEVELOPMENT; PRIORITY JOURNAL; RAPHE NUCLEUS; RESPIRATION CONTROL; RETICULAR FORMATION; SEROTONINERGIC NERVE CELL; SOLITARY TRACT NUCLEUS; STELLATE CELL;

EID: 0037532812     PISSN: 15660702     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1566-0702(03)00027-4     Document Type: Article

References (87)

1. Aicher S.A., Saravay R.H., Cravo S., Jeske I., Morrison S.F., Reis D.J., Milner T.A. Monosynaptic projections from the nucleus tractus solitarii to C1 adrenergic neurons in the rostral ventrolateral medulla: comparison with input from the caudal ventrolateral medulla. J. Comp. Neurol. 373:1996;62-75.
2. Andrezik J.A., Dormer K.J., Foreman R.D., Person R.J. Fastigial nucleus projections to the brain stem in beagles: pathways of autonomic regulation. Neuroscience. 11:1984;497-507.
3. Arango V., Ruggiero D.A., Callaway J.L., Anwar M., Mann J.J., Reis D.J. Catecholaminergic neurons in the ventrolateral medulla and nucleus of the solitary tract in the human. J. Comp. Neurol. 273:1988;224-240.
4. Barmack N.H., Fredette B.J., Mugnaini E. Parasolitary nucleus: a source of GABAergic vestibular information to the inferior olive of rat and rabbit. J. Comp. Neurol. 392:1998;352-372.
5. Batton R.R. III, Jayaraman A., Ruggiero D., Carpenter M.B. Fastigial efferent projections in the monkey: an autoradiographic study. J. Comp. Neurol. 174:1977;281-305.
6. 3H]GABA. J. Auton. Nerv. Syst. 50:1994;109-122.
7. Becker L.E., Zhang W. Vagal nerve complex in normal development and sudden infant death syndrome. Can. J. Neurol. Sci. 23:1996;24-33.
8. Beckstead R.M., Morse J.R., Norgren R. The nucleus of the solitary tract in the monkey: projections to the thalamus and brain stem nuclei. J. Comp. Neurol. 190:1980;259-282.
9. Benarroch E.E. Pain-autonomic interactions: a selective review. Clinic. Auton. Res. 11:2001;331-333.
10. Berger A.J. Dorsal respiratory group neurons in the medulla of the cat: spinal projections, responses to lung inflation and superior laryngeal nerve stimulation. Brain Res. 135:1977;231-254.
11. Berger A.J. Distribution of carotid sinus nerve afferent fibers to solitary tract nuclei of the cat using transganglionic transport of horseradish peroxidase. Neurosci. Lett. 14:1979;153-158.
12. Blessing W.B. The Lower Brainstem and Bodily Homeostasis. 1997;Oxford Univ. Press, New York.
13. Blessing W.B., Li Y.-W., Wesselingh S.L. Transneuronal transport of Herpes Simplex virus from the cervical vagus to brain neurons with axonal inputs to central vagal sensory nuclei in the rat. Neuroscience. 42:1991;261-274.
14. Ciriello J., Hrycyshyn A.W., Calaresu F.R. Glossopharyngeal and vagal afferent projections to the brain stem of the cat: a horseradish peroxidase study. J. Auton. Nerv. Syst. 4:1981;63-79.
15. Ciriello J., Hrycyshyn A.W., Calaresu F.R. Horseradish peroxidase study of brain stem projections of carotid sinus and aortic depressor nerves in the cat. J. Auton. Nerv. Syst. 4:1981;43-61.
16. Cottle M.K.W., Calaresu F.R. Projections from the nucleus and tractus solitarius in the cat. J. Comp. Neurol. 161:1975;143-158.
17. Cunningham E.T. Jr., Sawchenko P.E. Dorsal medullary pathways subserving oromotor reflexes in the rat: implications for the central neural control of swallowing. J. Comp. Neurol. 417:2000;448-466.
18. Dampney R.A.L., Goodshild A.K., Robertson L.G., Montgomery W. Role of ventrolateral medulla in vasomotor regulation: a correlative anatomical and physiological study. Brain Res. 249:1982;223-235.
19. Denavit-Saubie M., Kalia M., Pierrefiche O., Schweitzer P., Foutz A.S., Champagnat J. Maturation of brain stem neurons involved in respiratory rhythmogenesis: biochemical, bioelectrical and morphological properties. Biol. Neonate. 65:1994;171-175.
20. Dobbins E.G., Feldman J.L. Brainstem network controlling descending drive to phrenic motoneurons in rat. J. Comp. Neurol. 347:1994;64-86.
21. Fifer W.P., Myers M.M. Sudden fetal and infant deaths: shared characteristics and distinctive features. Semin. Perinatol. 26:2002;89-96.
22. Filiano J.J., Choi J.C., Kinney H.C. Candidate cell populations for respiratory chemosensitive fields in the human infant medulla. J. Comp. Neurol. 293:1990;448-465.
23. Finlay J.C.W., Katz D.M. The central organization of carotid body afferent projections to the brainstem of the rat. Brain Res. 571:1992;108-116.
24. Godement P., Vanselow J., Thanos S., Bonhoeffer F. A study in developing visual systems with a new method of staining neurons and their processes in fixed tissue. Development. 101:1987;697-713.
25. Golanov E.V., Reis D.J. Neurons of nucleus of the solitary tract synchronize the EEG and elevate cerebral blood flow via a novel medullary area. Brain Res. 892:2001;1-12.
26. Gorcs T.J., Liposits Z., Palay S.L., Chan-Palay V. Serotonin neurons on the ventral brain surface. Proc. Natl. Acad. Sci. U. S. A. 82:1985;7449-7452.
27. Guyenet P.G., Wang H. Pre-Bötzinger neurons with preinspiratory discharges "in vivo" express NK1 receptors in the rat. J. Neurophysiol. 86:2001;438-446.
28. Guyenet P.G., Koshiya N., Huangfu D., Baraban S.C., Stornetta R.L., Li Y.-W. Role of medulla oblongata in generation of sympathetic and vagal outflows. Holstege G., Bandler R., Saper C.B. Progress in Brain Research. vol. 107:1996;126-144 Elsevier.
29. Hancock M.B. Evidence for direct projection from the nucleus of the solitary tract onto medullary adrenaline cells. J. Comp. Neurol. 276:1988;460-467.
30. Hevner R.R., Kinney H.C. Reciprocal entorhinal-hippocampal connections established by human fetal midgestation. J. Comp. Neurol. 372:1996;384-394.
31. Hilaire G., Duron B. Maturation of the mammalian respiratory system. Physiol. Rev. 79:1999;325-360.
32. Jeske I., Morrison S.F., Cravo S.L., Reis D.J. Identification of baroreceptor reflex interneurons in the caudal ventrolateral medulla. Am. J. Physiol. 264:1993;R169-R178.
33. Kalia M., Mesulam M.M. Brain stem projections of sensory and motor components of the vagus complex in the cat: I. The cervical vagus and nodose ganglia. J. Comp. Neurol. 193:1980;435-465.
34. Kalia M., Mesulam M.M. Brain stem projections of sensory and motor components of the vagus complex in the cat: II. Laryngeal, tracheobronchial, pulmonary, cardiac and gastrointestinal branches. J. Comp. Neurol. 193:1980;468-508.
35. Kalia M., Feldman J.L., Cohen M.I. Afferent projections to the inspiratory neuronal region of the ventrolateral nucleus of the tractus solitarius. Brain Res. 171:1979;135-141.
36. Kawai Y., Senba E. Postnatal differentiation of local networks in the nucleus of the tractus solitarius. Neuroscience. 100:2000;109-114.
37. Kinney H.C., Burger P.C., Harrell F.E. Jr., Hudson R.P. Jr. 'Reactive gliosis' in the medulla oblongata of victims of the sudden infant death syndrome. Pediatrics. 72:1983;181-187.
38. 3H-naloxone binding to opiate receptors in the human fetal and infant brainstem. J. Comp. Neurol. 291:1990;55-78.
39. 3H]nicotine binding in the human brainstem. Neuroscience. 55:1993;1127-1137.
40. Kinney H.C., Filiano J.J., Sleeper L.A., Mandell F., Valdes-Dapena M., White W.F. Decreased muscarinic receptor binding in the arcuate nucleus in sudden infant death syndrome. Science. 269:1995;1446-1450.
41. 3H]quinuclidinyl benzilate binding to muscarinic cholinergic receptors in the developing human brainstem. J. Comp. Neurol. 362:1995;350-367.
42. Kinney H.C., Filiano J.J., White W.F. Medullary serotonergic network deficiency in the sudden infant death syndrome: review of a 15-year study of a single dataset. J. Neuropathol. Exp. Neurol. 60:2001;228-247.
43. Kopp N., Chigr F., Denoroy L., Gilly R., Jordan D. Absence of adrenergic neurons in nucleus tractus solitarius in sudden infant death syndrome. Neuropediatrics. 24:1993;25-29.
44. Lan C.T., Wen C.Y., Tseng G.F., Tan C.K., Ling E.A., Shieh J.Y. Efferent connections form the external cuneate nucleus to the medulla oblongata in the gerbil. Brain Res. 668:1994;107-116.
45. Loewy A.D., Burton H. Nuclei of the solitary tract: efferent projections to the lower brain stem and spinal cord of the cat. J. Comp. Neurol. 181:1978;421-450.
46. Loewy A.D., Wallach J.H., McKellar S. Efferent connections of the ventral medulla oblongata in the rat. Brains Res. Rev. 3:1981;63-80.
47. Lovick T.A. Projections from brainstem nuclei to the nucleus paragigantocellularis lateralis in the cat. J. Auton. Nerv. Syst. 16:1986;1-11.
48. Mansouri J., Panigrahy A., Assman S.F., Kinney H.C. Distribution of alpha2-adrenergic receptor binding in the developing human brainstem. Pediatr. Dev. Pathol. 4:2001;222-236.
49. McRitchie D.A., Tork I. The internal organization of the human solitary nucleus. Brain Res. Bull. 31:1993;171-193.
50. Miura M., Reis D.J. Termination and secondary projection of carotid sinus nerve in cat brain stem. Am. J. Physiol. 217:1969;142-153.
51. Moolenaar G., Rucker H.K. Autoradiographic study of brain stem projections from fastigial pressor areas. Brain Res. 114:1976;492-496.
52. Morest D.K. Experimental study of the projections of the nucleus of the tractus solitarius and the area postrema in the cat. J. Comp. Neurol. 130:1969;277-300.
53. Morilak D.A., Somogy P., McIlhinney R.A.J., Chalmers J. An enkephalin-containing pathway from nucleus tractus solitarius to the pressor area of the rostral ventrolateral medulla of the rabbit. Neuroscience. 31:1989;187-194.
54. Mtui E.P., Anwar M., Gomez R., Reis D.J. Projections from the nucleus tractus solitarii to the spinal cord. J. Comp. Neurol. 337:1993;231-252.
55. Mtui E.P., Anwar M., Reis D.J., Ruggiero D.A. Medullary visceral reflex circuits: local afferents to nucleus tractus solitarii synthesize catecholamines and project to thoracic spinal cord. J. Comp. Neurol. 351:1995;5-26.
56. Neff R.A., Mihalevich M., Mendelowitz D. Stimulation of NTS activates NMDA and non-NMDA receptors in rat cardiac vagal neurons in the nucleus ambiguus. Brain Res. 792:1998;277-282.
57. Norgren R. Projections from the nucleus of the solitary tract in the rat. Neuroscience. 3:1978;207-218.
58. Ohtake P.J., Simakajornboon N., Fehniger M.D., Xue Y.D., Gozal D. N-Methyl-D-aspartate receptor expression in the nucleus tractus solitarii and maturation of hypoxic ventilatory response in the rat. Am. J. Respir. Crit. Care Med. 162:2000;1140-1147.
59. Olszewski J., Baxter D. Cytoarchitecture of the Human Brain. 1954;Karger, Basel.
60. 3H]kainate binding in human brainstem sites vulnerable to perinatal hypoxia-ischemia. Neuroscience. 67:1995;441-454.
61. Panigrahy A., Filiano J.J., Sleeper L.A., Mandell F., Valdes-Dapena M., Krous H.F., Rava L.A., White W.F., Kinney H.C. Decreased kainate receptor binding in the arcuate nucleus of the sudden infant death syndrome. J. Neuropathol. Exp. Neurol. 56:1997;1253-1261.
62. Panigrahy A., Filiano J.J., Sleeper L.A., Mandell F., Valdes-Dapena M., Krous H.F., Rava L.A., Foley E., White W.F., Kinney H.C. Decreased serotonergic receptor binding in rhombic lip-derived regions of the medulla oblongata in the sudden infant death syndrome. J. Neuropathol. Exp. Neurol. 59:2000;377-384.
63. Panigrahy A., Rosenberg P.A., Assmann S., Foley E.C., Kinney H.C. Differential expression of glutamate receptor subtypes in human brainstem sites involved in perinatal hypoxia-ischemia. J. Comp. Neurol. 427:2000;196-208.
64. Paxinos G., Huang X.-F. Atlas of the Human Brainstem. 1995;Academic Press, San Diego.
65. Reis D.J., Golanov E.V., Ruggiero D.A., Sun M.-K. Sympathoexcitatory neurons of the rostral ventrolateral medulla are oxygen sensors and essential elements in the tonic and reflex control of the systemic and cerebral circulations. J. Hypertens. 12(Suppl. 10):1994;S159-S180.
66. Ross C.A., Ruggiero D.A., Reis D.J. Afferent projections to cardiovascular portions of the nucleus of the tractus solitarius in the rat. Brain Res. 223:1981;402-408.
67. Ross C.A., Ruggiero D.A., Reis D.J. Projections from the nucleus tractus solitarii to the rostral ventrolateral medulla. J. Comp. Neurol. 242:1985;511-534.
68. Ruggiero D.A., Underwood M.D., Mann J.J., Anwar M., Arango V. The human nucleus of the solitary tract: visceral pathways revealed with an "in vitro" postmortem tracing method. J. Auton. Nerv. Syst. 79:2000;181-190.
69. Ruiz Pesini P., Cifuentes J.M., Fernandez-Troconiz P. The nucleus of the tractus solitarius of the dog. A morphological and morphometric analysis. J. Anat. 176:1991;113-132.
70. Smith J.C., Ellenberger H.H., Ballanyi K., Richter D.W., Feldman J.L. Pre-Bötzinger complex: a brainstem region that may generate respiratory rhythm in mammals. Science. 254:1991;726-729.
71. Somogyi P., Minson J.B., Morilak D., Llewellyn-Smith I., McIlhinney J.R.A., Chalmers J. Evidence for an excitatory amino acid pathway in the brainstem and for its involvement in cardiovascular control. Brain Res. 496:1989;401-407.
72. Thor K.B., Helke C.J. Serotonin- and substance P-containing projections to the nucleus tractus solitarii of the rat. J. Comp. Neurol. 265:1987;275-293.
73. Thor K.B., Helke C.J. Catecholamine-synthesizing neuronal projections to the nucleus tractus solitarii of the rat. J. Comp. Neurol. 268:1988;264-280.
74. Tolcos M., McGregor H., Walker D., Rees S. Chronic prenatal exposure to carbon monoxide results in a reduction in tyrosine hydroxylase-immunoreactivity and an increase in choline acetyltransferase-immunoreactivity in the fetal medulla: implication for Sudden Infant Death Syndrome. J. Neuropathol. Exp. Neurol. 59:2000;218-228.
75. Törk I., McRitchie D.A., Rikard-Bell G.C., Paxinos G. Autonomic regulatory centers in the medulla oblongata. Paxinos G. The Human Nervous System. 1990;221-259 Academic Press, San Diego, CA.
76. Van Bockstaele E.J., Pieribone V.A., Aston-Jones G. Diverse afferents converge on the nucleus paragigantocellularis in the rat ventrolateral medulla: retrograde and anterograde tracing studies. J. Comp. Neurol. 290:1989;561-584.
77. von Bartheld C.S., Cunningham D.E., Rubel E.W. Neuronal tracing with DiI: decalcification, cryosectioning and photoconversion for light and electron microscopic analysis. J. Histochem. Cytochem. 38:1990;725-733.
78. von Euler C., Hayward J.N., Martilla I., Wyman R.J. Respiratory neurons of the ventrolateral nucleus of the solitary tract of cat: vagal input, spinal connections and morphological identification. Brain Res. 61:1973;1-22.
79. Wallach J.H., Loewy A.D. Projections of the aortic nerve to the nucleus tractus solitarius in the rabbit. Brain Res. 188:1980;247-251.
80. Wang J., Irnaten M., Neff R.A., Venkatesan P., Evans C., Loewy A.D., Mettenleiter T.C., Mendelowitz D. Synaptic and neurotransmitter activation of cardiac vagal neurons in the nucleus ambiguus. Ann. N.Y. Acad. Sci. 940:2001;237-246.
81. Wang W., Tiwari J.K., Bradley S.R., Zaykin A.V., Richerson G.B. Acidosis-stimulated neurons of the medullary raphe are serotonergic. J. Neurophysiol. 85:2001;2224-2235.
82. Wasserman A.M., Sahibzada N., Hernandez Y.M., Gillis R.A. Specific subnuclei of the nucleus tractus solitarius play a role in determining the duration of inspiration in the rat. Brain Res. 880:2000;118-130.
83. Xu F., Frazier D.T. Medullary respiratory neuronal activity modulated by stimulation of the fastigial nucleus of the cerebellum. Brain Res. 705:1995;53-64.
84. Zec N., Kinney H.C. Anatomic relationships of the human nucleus paragigantocellularis lateralis: a DiI labeling study. Auton. Neurosci. 89:2001;110-124.
85. 3H]LSD) binding to serotonin receptors in the human brainstem. J. Neuropathol. Exp. Neurol. 55:1996;114-126.
86. Zec N., Filiano J.J., Kinney H.C. Anatomic relationships of the human arcuate nucleus of the medulla: a DiI-labeling study. J. Neuropathol. Exp. Neurol. 56:1997;509-522.
87. Zhang L.L., Ashwell K.W. Development of the cyto- and chemoarchitectural organization of the rat nucleus of the solitary tract. Anat. Embryol. 203:2001;265-282.