Role of disulfiram in the in vitro inhibition of rat liver mitochondrial aldehyde dehydrogenase

Biochemical Pharmacology

Volumn 60, Issue 7, 2000, Pages 947-953

  Shen, Maryann L ^a   Lipsky, James J ^a   Naylor, Stephen ^a  

^a MAYO CLINIC   (United States)

Author keywords

Adduct structure; Aldehyde dehydrogenase; Disulfiram; Enzyme inhibition; Mass spectrometry; Protein drug interaction; Thiol oxidation

Indexed keywords

ALDEHYDE DEHYDROGENASE INHIBITOR; DISULFIRAM; RECOMBINANT ENZYME;

ALCOHOLISM; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISULFIDE BOND; DRUG ACTIVITY; DRUG INDICATION; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER MITOCHONDRION; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; RAT;

ALDEHYDE DEHYDROGENASE; ANIMALS; CHROMATOGRAPHY, LIQUID; DISULFIRAM; DITHIOTHREITOL; DRUG INTERACTIONS; ENZYME INHIBITORS; ESCHERICHIA COLI; MASS SPECTROMETRY; MITOCHONDRIA, LIVER; RATS; RECOMBINANT PROTEINS; SERINE ENDOPEPTIDASES;

EID: 0034308085     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(00)00435-4     Document Type: Article

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