Preventive measures section 1: Early interventions

Chemical Immunology and Allergy

Volumn 84, Issue , 2004, Pages 135-151

  Høst, Arne ^a   Boner, Attilio ^b   Odhiambo, Joseph ^c  

^a ODENSE UNIVERSITY HOSPITAL   (Denmark)

^b UOC Oncoematologia Pediatrica Policlinico GB Rossi   (Italy)

^c KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ALLERGEN; BRONCHODILATING AGENT; CORTICOSTEROID; CROMOGLYCATE DISODIUM; IMMUNOGLOBULIN E; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MILK PROTEIN; NEDOCROMIL SODIUM; NONSTEROID ANTIINFLAMMATORY AGENT; POLLEN ANTIGEN; THEOPHYLLINE; TOBACCO SMOKE;

AIR POLLUTANT; ALLERGIC ASTHMA; ALLERGY; ASTHMA; ATOPY; BREAST FEEDING; BREAST MILK; BRONCHUS HYPERREACTIVITY; CHILD; CHILD NUTRITION; CIGARETTE SMOKING; CONTROLLED STUDY; DERMATOPHAGOIDES; DISEASE SEVERITY; DRUG HYPERSENSITIVITY; EVIDENCE BASED MEDICINE; FOOD ALLERGY; GASTROESOPHAGEAL REFLUX; HIGH RISK POPULATION; HUMAN; IMMUNOTHERAPY; INFANT; MILK ALLERGY; PASSIVE SMOKING; POLLEN ALLERGY; PRACTICE GUIDELINE; PREGNANCY; PRIORITY JOURNAL; REVIEW; RHINOSINUSITIS; RISK FACTOR; SYMPTOMATOLOGY; TOBACCO; VACCINATION; WHEEZING;

ALLERGENS; CHILD, PRESCHOOL; EVIDENCE-BASED MEDICINE; HUMANS; HYPERSENSITIVITY; HYPERSENSITIVITY, IMMEDIATE; IMMUNOTHERAPY; INFANT; INFANT, NEWBORN; RISK FACTORS;

EID: 6044263329     PISSN: 16602242     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Review

References (145)

1. Wahn U: What drives the allergic march? Allergy 2000;55:591-559. (IV)
2. Høst A, Halken S: The role of allergy in childhood asthma. Allergy 2000;55:600-608. (IV)
3. Halken S, Høst A: The lessons of noninterventional and interventional prospective studies on the development of atopic disease during childhood. Allergy 2000;55:793-802. (IV)
4. Trindade JC: The importance of diagnosis of allergy in early wheezing. Pediatr Allergy Immunol 1998;9:23-29. (III)
5. Bergmann RL, Edenharter G, Bergmann KE, Guggemoos-Holzmarm I, Forster J, Bauer CP, et al: Predictability of early atopy by cord blood-IgE and parental history. Clin Exp Allergy 1997;27:752-760. (IIa)
6. Hansen LG, Halken S, Høst A, Møller K, Østerballe O: Prediction of allergy from family history and cord blood IgE levels. A follow-up at the age of 5 years. Cord blood IgE IV. Pediatr Allergy Immunol 1993;4:34-40. (IIa)
7. Kjellman N-IM: Atopic disease in seven-year-old children. Acta Paediatr Scand 1977;66: 565-571. (III)
8. Nilsson L: Risk factors for atopic disease in childhood; Linköping University Medica Dissertation No. 556. Linköping University, 1998. (IIa)
9. Wahn U, von Mutius E: Childhood risk factors for atopy and the importance of early intervention. J Allergy Clin Immunol 2001;107:567-574. (IV)
10. Grulee C, Sanford H: The influence of breast and artificial feeding on infantile eczema. J Pediatr 1936;72:411-414. (IIa)
11. Høst A, Husby S, Østerballe O: A prospective study of cow's milk allergy in exclusively breastfed infants. Acta Paediatr Scand 1988;77:663-700. (IIa)
12. Saarinen UM, Kajosaari M: Breastfeeding as prophylaxis against atopic disease: Prospective follow-up study until 17 years old. Lancet 2001;346:1065-1069. (IIa)
13. Wright AL, Holberg CJ, Taussig LM, Martinez FD: Relationship of infant feeding to recurrent wheezing at age 6 years. Arch Pediatr Adolesc Med 1995;149:758-763. (IIa)
14. Oddy WH, Holt PG, Sly PD, Read AW, Landau LI, Stanley FJ, et al: Association between breast feeding and asthma in 6 year old children: Findings of a prospective birth cohort study. BMJ 1999;319:815-819. (IIa)
15. Gdalevich M, Mimouni D, David M, Mimouni M: Breast-feeding and the onset of atopic dermatitis in childhood: A systematic review and meta-analysis of prospective studies. J Am Acad Dermatol 2001;45:520-527. (IIa)
16. Gdalevich M, Mimouni D, Mimouni M: Breast-feeding and the risk of bronchial asthma in childhood: A systematic review with meta-analysis of prospective studies. J Pediatr 2001;139:261-266. (IIa)
17. Odijk J, Kull I, Borres MP, Brandtzaeg P, Edberg U, Hanson LA, et al: Breast-feeding and allergic disease: A multidisciplinary review of the literature (1966-2001) on the mode of early feeding in infancy and its impact on later atopic manifestations. Allergy 2003;58:833-843. (IIa)
18. Saarinen KM, Juntunen-Backman K, Järvenpää A-L, Kultunen P, Lope L, Renlund M, et al: Supplementary feeding in maternity hospitals and the risk of cow's milk allergy: A prospective study of 6209 infants. J Allergy Clin Immunol 1999;104:457-461. (Ib)
19. Lucas A, Brooke OG, Morley R, Cole TJ, Bamford MF: Early diet of preterm infants and development of allergic or atopic disease: Randomized prospective study. BMJ 1990;300:837-840. (Ib)
20. Lindfors ATB, Danielsson L, Enocksson E, Johansson SGO, Westin S: Allergic symptoms up to 4-6 years in children given cow milk neonatally. A prospective study. Allergy 1992;47:207-211. (Ib)
21. Gustafsson D, Löwhagen T, Andersson K: Risk of developing atopic disease after early feeding with cow's milk based formula. Arch Dis Child 1992;67:1008-1010. (III)
22. de Jong MH, Scharp-van der Linden VTM, Aalberse RC, Oosting J, Tijssen JGP, de Groot CJ: Randomised controlled trial of brief neonatal exposure to cow's milk on the development of atopy. Arch Dis Child 1998;79:126-130. (Ib)
23. Hast A, Koletzko B, Dreborg S, Muraro A, Wahn U, Aggett P, et al: Dietary products used in infants for treatment and prevention of food allergy. Joint Statement of the European Society for Paediatric Allergology and Clinical Immunology (ESPACI) Committee of Hypoallergenic Formulas and the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) Committee on Nutrition. Arch Dis Child 1999;81:80-84. (IV)
24. Fergusson DM, Horwood LJ, Shannon FT: Early solid food feeding and recurrent childhood eczema: A 10-year longitudinal study. Pediatrics 1990;86:541-546. (IIa)
25. Kajosaari M, Saarinen UM. Prophylaxis of atopic disease by six months' total solid food elimination. Evaluation of 135 exclusively breast-fed infants of atopic families. Acta Paediatr Scand 1983;72:411-414. (IIa)
26. Fälth-Magnusson K, Öhman H, Kjellman N-IM: Maternal abstention from cow milk and egg in allergy risk pregnancies. Effect on antibody production in the mother and the newborn. Allergy 1987;42:64-73. (Ib)
27. Fälth-Magnusson K, Kjellman N-IM: Allergy prevention by maternal elimination diet during late pregnancy - A 5-year follow-up of a randomized study. J Allergy Clin Immunol 1992;89: 709-713. (Ib)
28. Lilja G, Dannaeus A, Foucard T, Graff LV, Johansson SGO, Ohman H: Effects of maternal diet during late pregnancy and lactation on the development of atopic diseases in infants up to 18 months of age - In vivo results. Clin Exp Allergy 1989;19:473-479. (Ib)
29. Hattevig G, Sigurs N, Kjellman B: Effects of maternal dietary avoidance during lactation on allergy in children at 10 years of age. Acta Paediatr 1999;88:7-12. (Ib)
30. Strachan DP, Cook DG: Parental smoking and childhood asthma: Longitudinal and case-control studies. Thorax 1998;53:204-212. (IV)
31. Tager IB: Smoking and childhood asthma - Where do we stand? Am J Respir Crit Care Med 1998;158:349-351. (IV)
32. Halken S, Høst A, Nilsson L, Taudorf E: Passive smoking as a risk factor for development of obstructive respiratory disease and allergic sensitization. Allergy 1995;50:97-105. (IV)
33. Martinez FD, Wright AL, Taussig LM, et al: Asthma and wheezing in the first six years of life. N Engl J Med 1995;332:133-138. (IIa)
34. Young S, Souef PN, Geelhoed CG, et al: The influence of a family history of asthma and parental smoking on airway responsiveness in early infancy. N Engl J Med 1991;324:1168-1173. (IIa)
35. Hanrahan JP, Tager IB, Segal MR, et al: The effect of maternal smoking during pregnancy on early infant lung function. Am Rev Respir Dis 1992;145:1129-1135. (IIa)
36. Carlsen KL, Jakkola LLK, Nafstad P, Carlsen K-H: In utero exposure to cigarette smoking influences lung function at birth. Eur Respir J 1997;10:1774-1779. (IIa)
37. Stick SM, Burton PR, Gurrin L, Sly PD, LeSouef PN: Effects of maternal smoking during pregnancy and a family history of asthma on respiratory function in newborn infants. Lancet 1996; 348:1060-1064. (IIa)
38. Milner AD, Marsh MJ, Ingram DM, Fox GF, Susiva C: Effects of smoking in pregnancy on neonatal lung function. Arch Dis Child Fetal Neonatal Ed 1999;80:F8-F14. (IIa)
39. Cook DG, Strachan DP: Summary of effect of parental smoking on the respiratory health of children and implications for research. Thorax 1999;54:357-366. (Ia)
40. Lindfors A, van Hage-Hamsten M, Rietz H, Wickman M, Nordvall L: Influence of interaction of environmental risk factors and sensitization in young asthmatic children. J Allergy Clin Immunol 1999;194:755-762. (IIa)
41. Kulig M, Luck W, Lau S, Niggeman B, Bergman R, Klettke U, et al: Effect of pre- and postnatal tobacco smoke exposure on specific sensitization to food and inhalant allergens during the first 3 years of life. Allergy 1999;54:220-228. (IIa)
42. Jones AP: Asthma and domestic air quality. Soc Sci Med 1998;47:755-764. (IV)
43. Brunekreef B, Dockery DW, Krzyzanowski M: Epidemiologic studies on short-term effects on low levels of major ambient air pollution components. Environ Health Perspect 1995;103:3-13. (IV)
44. Polosa R: Prevalence of atopy and urban air pollution: Dirty business (editorial). Clin Exp Allergy 2001;29:1439-1441. (IV)
45. Boezen HM, van der Zee SC, Postma DS, Vonk JM, Gerritsen J, Hoek G, et al: Effects of ambient air pollution on upper and lower respiratory symptoms and peak expiratory flow in children. Lancet 1999;353:874-878. (IIa)
46. Kjellman N-IM: IgE in neonates is not suitable for general risk screening. Pediatr Allergy Immunol 1994;5:1-4. (IV)
47. Chandra RK, Shakuntla P, Hamed A: Influence of maternal diet during lactation and use of formula feeds on development of atopic eczema in high risk infants. BMJ 1989;299:228-230. (Ib)
48. Halken S, Høst A, Hansen LG, Østerballe O: Preventive effect of feeding high-risk infants a casein hydrolysate formula or an ultrafiltrated whey hydrolysate formula. A prospective, randomized, comparative clinical study. Pediatr Allergy Immunol 1993;4:173-181. (Ib)
49. Zeiger RS, Heller S, Mellon MH, Forsythe AB, O'Connor RD, Hamburger RN, et al: Effect of combined maternal and infant food-allergen avoidance on development of atopy in early infancy: A randomized study. J Allergy Clin Immunol 1989;84:72-89. (Ib)
50. Zeiger RS, Heller S, Sampson HA: Genetic and environmental factors affecting the development of atopy through age 4 in children of atopic parents: A prospective randomized controlled study of food allergen avoidance. Pediatr Allergy Immunol 1992;3:110-127. (Ib)
51. Zeiger RS, Heller RS: The development and prediction of atopy in high-risk children: Follow-up at age seven years in a prospective randomized study of combined maternal and infant food allergen avoidance. J Allergy Clin Immunol 1995;95:1179-1190. (Ib)
52. Von Berg A, Koletzko S, Grubl A, Filipiak-Pittroff B, Wichmann HE, Bauer CP, et al: The effect of hydrolized cow's milk formula for allergy prevention in the first year of life: The German Infant Nutrition Intervention Study, a randomized double-blind trial. J Allergy Clin Immunol 2003;111:533-540. (Ib)
53. Halken S, Hansen Skamstrup K, Jacobsen HP, Estmann A, Engberg Fælling A, Hansen LG, et al: Comparison of a partially hydrolyzed infant formula with two extensively hydrolyzed formulas for allergy prevention: A prospective, randomized study. Pediatr Allergy Immunol 2000;11:149-161. (Ib)
54. Vandenplas Y, Deneyr M, Sacre L, Loeb H: Preliminary data on a field study with a new hypoallergenic formula. Eur J Pediatr 1988;148:274-277. (Ib)
55. Chandra RK, Hamed A: Cumulative incidence of atopic disorders in high risk infants fed whey hydrolysate, soy, and conventional cow milk formulas. Ann Allergy 1991;67:129-132. (Ib)
56. Chandra RK, Singh G, Shridhara B: Effect of feeding whey hydrolysate, soy and conventional cow milk formula on incidence of atopic disease in high risk infants. Ann Allergy 1989;63:102-106. (Ib)
57. Vandenplas Y, Hauser B, Van den Borre C, Sacre L, Dab I: Effect of a whey hydrolysate prophylaxis of atopic disease. Ann Allergy 1992;68:419-424. (Ib)
58. Vandenplas Y, Hauser B, Van den Borre C, et al: The long-term effect of a partial whey hydrolysate formula on the prophylaxis of atopic disease. Eur J Pediatr 1995;154:488-494. (Ib)
59. Marini A, Agosti M, Motta G, Mosca F: Effects of a dietary and environmental prevention programme on the incidence of allergic symptoms in high risk infants: Three years follow-up. Acta Paediatr 1996;85:1-122. (Ib)
60. Chandra RK: Five-year follow-up of high-risk infants with family history of allergy who were exclusively breast-fed or fed partial whey hydrolysate, soy, and conventional cow's milk fomulas. J Pediatr Gastroenterol Nutr 1997;24:380-388. (Ib)
61. Burr ML, Merrett TG, Dunstan FDJ, Magguire MJ: The development of allergy in high-risk children. Clin Exp Allergy 1997;27:1247-1253. (IIa)
62. Bardare M, Vaccari, Allevie E, Brunelli L, Coco F, de Caspari GC, et al: Influence of dietary manipulation on incidence of atopic disease in infants at risk. Ann Allergy 1993;71:366-371. (IIa)
63. Sears M, Holdaway MD, Flannery EM, Herbison GP, Silva PA: Parental and neonatal risk factors for atopy, airway hyperresponsiveness, and asthma. Arch Dis Child 1996;75:392-398. (IIa)
64. Kuehr J, Frischer T, Meinert R, Barth R, Schraub S, Urbanek R, et al: Sensitization to mite allergens is a risk factor for early and late onset of asthma and for persistence of asthmatic signs in children. J Allergy Clin Immunol 1995;95:655-662. (IIa)
65. Peat JK, Salome CM, Woolcock AJ: Longitudinal changes in atopy during a 4-year period: Relation to bronchial hyperresponsiveness and respiratory symptoms in a population sample of Australian schoolchildren. J Allergy Clin Immunol 1990;85:65-74. (IIa)
66. Platts-Mills TAE, Vervloet D, Thomas WR, et al: Indoor allergens and asthma: Report of the Third International Workshop. J Allergy Clin Immunol 1997;100:1-24. (IV)
67. Peat JK, Tovey E, Toelle BG, Haby MM, Gray EJ, Mahmic A, et al: House dust mite allergens. A major risk factor for childhood asthma in Australia. Am J Respir Crit Care Med 1996;153: 141-146. (IV)
68. Sporik R, Holgate ST, Platts-Mills TAE, Cogswell JJ: Exposure to house dust mite allergy (Der p 1) and the development of asthma in childhood. N Engl J Med 1990;323:502-507. (IIa)
69. Wahn U, Lau S, Bergman R, Kulig M, Forster J, Bergman K, et al: Indoor allergen exposure is a risk factor for sensitization during the first three years of life. J Allergy Clin Immunol 1997;99:763-769. (IIa)
70. Roost HP, Kûnzli N, Schildler C, Jarvis S, Chinn S, Perruchoud AP, et al: Role of current and childhood exposure to cat and atopic sensitisation. J Allergy Clin Immunol 1999;104:941-947. (III)
71. Apelberg JB, Yutaka A, Jaakkola JJK: Systematic review: Exposure to pets and risk of asthma and asthma-like symptoms. J Allergy Clin Immunol 2001;107:455-460. (Ia)
72. Lau S, Illi S, Sabina L, Sommerfeld C, Niggemann B, Bergmann R, von Mutius E, Wahn U: Early exposure to house-dust mite and cat allergens and development of childhood asthma: A cohort study. Lancet 2000;356:1392-1397. (IIa)
73. Squillace SP, Sporik RB, Rakes G, Couture N, Lawrence A, Merriam S, et al: Sensitization to dust mites as a dominant risk factor for asthma among adolescents living in central Virginia. Multiple regression analysis of a population-based study. Am J Respir Crit Care Med 1997;156: 1760-1764. (III)
74. Sporik R, Squillace SP, Ingram JM, Rakes G, Honsinger RW, Platts-Mills TA: Mite, cat, and cockroach exposure, allergen sensitisation, and asthma in children: A case-control study of three schools. Thorax 1999;54:675-680. (III)
75. Custovic A, Taggart SC, Francis HC, Chapman MD, Woodcock A: Exposure to house dust mite allergens and the clinical activity of asthma. J Allergy Clin Immunol 1996;98:64-72. (III)
76. Holberg CJ, Wright AL, Martinez FD, Ray CG, Taussig LM, Lebowitz MD: Risk factors for respiratory syncytial virus-associated lower respiratory illnesses in the first year of life. Am J Epidemiol 1991;133:1135-1351. (IIa)
77. Custovic A, Simpson A, Chapman MD, Woodcock A: Allergen avoidance in the treatment of asthma and atopic disorders. Thorax 1998;53:63-72. (IV)
78. Illi S, von Mutius E, Lau S, Nickel R, Niggemann B, Sommerfeld C, et al: The pattern of atopic sensitization is associated with the development of asthma in childhood. J Allergy Clin Immunol 2001;108:709-714. (IIa)
79. Sasai K, Furukawa S, Muto T, Baba M, Yabuta K, Fukuwutari Y: Early detection of specific IgE antibody against house dust mite in children at risk of allergic disease. J Pediatr 1996;128: 834-840. (IIa)
80. Nishioka K, Yasueda H, Saito H: Preventive effect of bedding encasement with microfine fibers on mite sensitization. J Allergy Clin Immunol 1998;101:28-32. (Ib)
81. Arshad SH, Matthews S, Gant C, Hide DW: Effect of allergen avoidance on development of allergic disorders in infancy. Lancet 1992;339:1493-1497. (Ib)
82. Hide DW, Matthews S, Matthews L, et al: Effect of allergen avoidance in infancy on allergic manifestations at age two years. J Allergy Clin Immunol 1994;93:842-846. (Ib)
83. Hide DW, Matthews S, Tariq S, Arshad SH: Allergen avoidance in infancy and allergy at 4 years of age. Allergy 1996;51:89-93. (Ib)
84. Chan-Yeung M, Manfreda J, Dimich-Ward H, Lam J, Ferguson A, Warren P, et al: Mite and cat allergen levels in homes and severity of asthma. Am J Respir Crit Care Med 1995;152: 1805-1811. (IIa)
85. Custovic A, Simpson BM, Simpson A, Hallam C, Craven M, Brutsche M, et al: Manchester Asthma and Allergy Study: Low-allergen environment can be achieved and maintained during pregnancy and in early life. J Allergy Clin Immunol 2000;105(2 pt 1):252-258. (Ib)
86. Custovic A, Simpson BM, Simpson A, Kissen P, Woodcock A: NAC Manchester Asthma and Allergy Study Group: Effect of environmental manipulation in pregnancy and early life on respiratory symptoms and atopy during first year of life: A randomised trial. Lancet 2001;358: 188-193. (Ib)
87. Boner AL, Niero E, Antolini I, Valetta EA: Pulmonary function and bronchial hyperreactivity in asthmatic children with house dust mite allergy during prolonged stay in the Italian Alps (Misurini 1756 m). Ann Allergy 1985;54:42-45. (IIb)
88. Piacentini GL, Vincentini L, Mazzi P, Chilosi M, Martinati L, Boner AL: Mite-antigen avoidance can reduce bronchial epithelial shedding in allergic asthmatic children. Clin Exp Allergy 1998;28:561-567. (IIb)
89. Piacentini GL, Martinati L, Mingoni S, Boner AL: Influence of allergen avoidance on the eosinophil phase of airway inflammation in children with asthmatic asthma. J Allergy Clin Immunol 1996;97:1079-1084. (IIb)
90. Piacentini GL, Martinati L, Fornari A, Comis A, Carcereri L, Boccagni P, Boner AL: Antigen avoidance in a mountain environment: Influence on basophil releasability in children with allergic asthma. J Allergy Clin Immunol 1993;92:644-650. (IIb)
91. Grootendorst DC, Dahlen SE, Van Den Bos JW, Duiverman EJ, Veselic-Charvat M, Vrijlandt EJ, et al: Benefits of high altitude allergen avoidance in atopic adolescents with moderate to severe asthma, over and above treatment with high dose inhaled steroids. Clin Exp Allergy 2001;31: 400-408. (Ib)
92. Arlian LG, Platts-Mills TA: The biology of dust mites and the remediation of mite allergens in allergic disease. J Allergy Clin Immunol 2001;107(suppl 3):S406-S413. (IV)
93. Harving H, Korsgaard J, Dahl R: Clinical efficacy of reduction in house-dust mite exposure in specially designed, mechanically ventilated 'healthy' homes. Allergy 1994;49:866-870. (IIa)
94. Wickman M, Nordvall SL, Pershagen G, Korsgaard J, Johansen N, Sundell J: Mite allergens during 18 months of intervention. Allergy 1994;49:114-119. (IIa)
95. Ehnert B, Lau-Schadendorf S, Weber A, Buettner P, Schou C, Wahn U: Reducing domestic exposure to dust mite allergen reduces bronchial hyperreactivity in sensitive children with asthma. J Allergy Clin Immunol 1992;90:135-138. (Ib)
96. Marks GB, Tovey ER, Green W, Shearer M, Salome CM, Woolcock AJ: House dust mite allergen avoidance: A randomized controlled trial of surface chemical treatment and encasement of bedding. Clin Exp Allergy 1994;24:1078-1083. (Ib)
97. Marks GB, Tovey ER, Toelle BG, Wachinger S, Peat JK, Woolcock AJ: Mite allergen (Der p 1) concentration in houses and its relation to the presence and severity of asthma in a population of Sydney schoolchildren. J Allergy Clin Immunol 1995;96:441-448. (IIa)
98. Marks GB, Tovey ER, Green W, Shearer M, Salome CM, Woolcock AJ: The effect of changes in house dust mite allergen exposure on the severity of asthma. Clin Exp Allergy 1995;25:114-118. (IIa)
99. Weeks J, Oliver J, Birmingham K, Crewes A, Carswell F: A combined approach to reduce mite allergen in the bedroom. Clin Exp Allergy 1995;25:1179-1183. (Ib)
100. Tan BB, Weald D, Strickland I, Friedmann PS: Double-blind controlled trial of effect of housedust-mite allergen avoidance on atopic dermatitis. Lancet 1996;347:15-18. (Ib)
101. Carswell F, Birmingham K, Oliver J, Crewes A, Weeks J: The respiratory effects of reduction of mite allergen in the bedrooms of asthmatic children - A double-blind controlled trial. Clin Exp Allergy 1996;26:386-396. (Ib)
102. Halken S, Niklassen U, Hansen LGH, Nielsen F, Høst A, Østerballe O, et al: Encasing of mattresses in children with asthma and house dust mite allergy (abstract). J Allergy Clin Immunol 1997;99:S320. (Ib)
103. Frederick JM, Warner JO, Jessop WJ, Enander I, Warner JA: Effect of a bed covering system in children with asthma and house dust mite hypersensitivity. Eur Respir J 1997;10: 361-366. (Ib)
104. Van der Heide S, Kauffman HF, Dubois AE, de Monchy JG: Allergen reduction measures in houses of allergic asthmatic patients: Effects of air-cleaners and allergen-impermeable mattress covers. Eur Respir J 1997;10:1217-1223. (Ib)
105. Shapiro GG, Wighton TG, Chinn T, Zuckrman J, Eliassen AH, Picciano JF, et al: House dust mite avoidance for children with asthma in homes of low-income families. J Allergy Clin Immunol 1999;103:1069-1074. (Ib)
106. Cloosterman SG, Schermer TR, Bijl-Hofland ID, van der HS, Brunekreef B, Van Den Elshout FJ, et al: Effects of house dust mite avoidance measures on Der p 1 concentrations and clinical condition of mild adult house dust mite-allergic asthmatic patients, using no inhaled steroids. Clin Exp Allergy 1999;29:1336-1346. (Ib)
107. Warner JA, Frederick JM, Bryant TN, Weich C, Hunter C, Stephen FR, et al: Mechanical ventilation and high-efficiency vacuum cleaning: A combined strategy of mite and mite allergen reduction in the control of mite-sensitive asthma. J Allergy Clin Immunol 2000;105:75-82. (Ib)
108. Vanlaar CH, Peat JK, Marks GB, Rimmer J, Tovey ER: Domestic control of house dust mite allergen in children's beds. J Allergy Clin Immunol 2000;105:1130-1133. (III)
109. Carswell F, Oliver J, Weeks J: Do mite avoidance measures affect mite and cat airborne allergens? Clin Exp Allergy 1999;29:193-200. (Ib)
110. Holm L, Ohman S, Bengtsson A, Hage-Hamsten M, Scheynius A: Effectiveness of occlusive bedding in the treatment of atopic dermatitis - A placebo-controlled trial of 12 months' duration. Allergy 2001;56:152-158. (Ib)
111. Gotzsche PC, Hammarquist C, Burr M: House dust mite control measures in the management of asthma: Meta-analysis. BMJ 1998;317:1105-1110. (Ia)
112. Gotzsche PC, Johansen HK, Burr ML, Hammarquist C: House dust mite control measures for asthma. Cochrane Database Syst Rev 2001, CD001187. (Ia)
113. McDonald LG, Tovey E: The role of water temperature and laundry procedures in reducing house dust mite populations and allergen content of bedding. J Allergy Clin Immunol 1992;90: 599-608. (IIb)
114. Collofff M, Taylor C, Merrett TG: The use of domestic steam cleaning for the control of house dust mites. Clin Exp Allergy 1995;25:1061-1066. (IIb)
115. Popplewell EJ, Innes VA, Lloyd-Hughes S, Jenkins EL, Khdir K, Bryant TN, et al: The effects of high-efficiency and standard vacuum-cleaners on mite, cat and dog allergen levels and clinical progress. Pediatr Allergy Immunol 2000;11:142-148. (Ib)
116. Nimmagadda SR, Szefler SJ, Spahn JD, Surs W, Leung DY: Allergen exposure decreases glucocorticoid receptor binding affinity and steroid responsiveness in atopic asthmatics. Am J Respir Crit Care Med 1997;155:87-93. (III)
117. Abramson R, Puy R, Weiner JM: Immunotherapy in asthma: An updated systematic review. Allergy 1999;54:1022-1041. (Ia)
118. Varney VA, Hamid QA, Gaga M, Ying S, Jacobson M, Frew AJ, et al: Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses. J Clin Invest 1993;92:644-651. (Ib)
119. Bousquet J, Lockey RF, Malling H-J: Allergen immunotherapy: Therapeutic vaccines for allergic diseases. WHO Position paper. Allergy 1998;53(suppl 44):1-42. (IV)
120. Durham SR, Walker SM, Varga E-M, Jacobson MR, O'Brien F, Noble B, et al: Long-term clinical effect of grass-pollen immunotherapy. N Engl J Med 1999;341:468-475. (Ib)
121. Abramson MJ, Puy RM, Weiher JM: Is allergen immunotherapy effective in asthma? Am J Respir Crit Med 1995;151:969-974. (Ia)
122. Gruber W, Eber E, Mileder P, et al: Effect of specific immunotherapy with house dust mite extract on the bronchial responsiveness of paediatric asthma patients. Clin Exp Allergy 1999;29: 176-781. (Ib)
123. Moller C, Dreborg S, Ferdousi HA, Halken S, Host A, Jacobsen L, et al: Pollen immunotherapy reduces the development of asthma in children with seasonal rhinoconjunctivitis (the PAT-study). J Allergy Clin Immunol 2002;109:251-256. (Ib)
124. Des Roches AD, Paradis L, Menardo JL, Bouges S, Daurés J-P, Bousquet J: Immunotherapy with a standardized Dermatophagoides pteronyssinus extract. VI. Specific immunotherapy prevents the onset of new sensitizations in children. J Allergy Clin Immunol 1997;99:450-453. (IIa)
125. Grembiale RD, Camporota L, Naty S, Tranfa CM, Djukanovic R, Marsico SA: Effects of specific immunotherapy in allergic rhinitic individuals with bronchial hyperresponsiveness. Am J Respir Crit Care Med 2000;162:2048-2052. (Ib)
126. Pajno GB, Barberio G, De Luca F, Morabito L, Parmiani S: Prevention of new sensitizations in asthmatic children monosensitized to house dust mite by specific immunotherapy. A six-year follow-up study. Clin Exp Allergy 2001;31:1392-1397. (IIa)
127. Purello-D'Ambrosio F, Gangemi S, Merendino RA, Isola S, Puccinelli P, Parmiani S, et al: Prevention of new sensitizations in monosensitized subjects submitted to specific immunotherapy or not. A retrospective study. Clin Exp Allergy 2001;31:1295-1302. (III)
128. Iikura Y, Naspitz CM, Mikawa H, et al: Prevention of asthma by ketotifen in infants with atopic dermatitis. Ann Allergy 1992;68:233-236. (Ib)
129. Wahn U, ETAC Study Group: Allergic factors associated with the development of asthma and the influence of cetirizine in a double-blind, randomised, placebo-controlled trial: First results of ETAC. Pediatr Allergy Immunol 1998;9:116-124. (Ib)
130. Bustos GJ, Bustos D, Bustos GJ, Romero O: Prevention of asthma with ketotifen in preasthmatic children: A three-year follow-up study. Clin Exp Allergy 1995;25:568-573. (Ib)
131. Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention. National Institutes of Health. National Hearth, Lung and Blood Institute. Revised 2002. www.ginasthma.com. (Ia)
132. Agertoft L, Pedersen S: Effects of long-term treatment with an inhaled corticosteroid on growth and pulmonary function in asthmatic children. Respir Med 1994;88:373-381. (IIa)
133. Zeiger RS, Dawson C, Weiss S: Relationships between duration of asthma and asthma severity among children in the Childhood Asthma Management Program. J Allergy Clin Immunol 1999;103:376-387. (Ib)
134. Haahtela T, Järvinen M, Kava T, Kiviranta K, Koskinen K, Lehtonen K, et al: Effects of reducing or discontinuing inhaled budesonide in patients with mild asthma. N Engl J Med 1994;331: 700-705. (Ib)
135. Mason A, Nieto A, Nieto FJ, Menendez R, Boquete M, Brines J: Prognostic factors in childhood asthma: A logistic regression analysis. Ann Allergy 1994;73:455-461. (Ib)
136. Knorr B, Franchi LM, Bisgaard H, Vermeulen JH, LeSouef P, Santanello N, et al: Montelukast, a leukotriene receptor antagonist, for the treatment of persistent asthma in children aged 2 to 5 years. Pediatrics 2001;108:E48. (Ib)
137. Williams B, Noonan G, Reiss TF, Knorr B, Guerra J, White R, et al: Long-term asthma control with oral montelukast and inhaled beclomethasone for adults and children 6 years and older. Clin Exp Allergy 2001;31:845-854. (Ib)
138. Knorr B, Matz J, Bernstein JA, Nguyen H, Seidenberg BC, Reiss TF, et al: Montelukast for chronic asthma in 6- to 14-year-old children: A randomized, double-blind trial. Pediatric Montelukast Study Group. JAMA 1998;279:1181-1186. (Ib)
139. Simons FE, Villa JR, Lee BW, Teper AM, Lyttle B, Aristizabal G, Laessig W, Schuster A, Perez-Frias J, Sekerel BE, Menten J, Leff JA: Montelukast added to budesonide in children with persistent asthma: A randomized, double-blind, crossover study. J Pediatr. 2001;138:694-698. (Ib)
140. Phipatanakul W, Nowak-Wegrzyn A, Eggleston PA, Van Natta M, Kesavan J, Schuberth K, Wood RA: The efficacy of montelukast in the treatment of cat allergen-induced asthma in children. J Allergy Clin Immunol 2002;109:794-799. (Ib)
141. Barnes PJ, Pauwels RA: Theophylline in the management of asthma: Time for reappraisal? Eur Respir J 1994;7:579-591. (IV)
142. Bousquet J, Van Cauwenberge P, Khaltaev N: Aria Workshop Group; World Health Organization: Allergic rhinitis and its impact on asthma. J Allergy Clin Immunol 2001;108:147s-334s. (Ib)
143. Szczeklik A, Nizankowska E, Duplaga M: Natural history of aspirin-induced asthma. Eur Respir J 2000;16:432-436. (IIb)
144. Theodoropoulos DS, Lockey RF, Boyce HW Jr, Bukantz SC: Gastroesophageal reflux and asthma: A review of pathogenesis, diagnosis, and therapy. Allergy 1999;54:651-661. (IIa)
145. GORD 2, Gibson PG, Henry RL, Coughlan JL: Gastro-oesophageal reflux treatment for asthma in adults and children (Cochrane Review). The Cochrane Library, Issue 2. Oxford, Update Software, 2001. (I)