Extracellular acidification elicits a chloride current that shares characteristics with ICl(swell)

American Journal of Physiology - Cell Physiology

Volumn 287, Issue 5 56-5, 2004, Pages

  Nobles, Muriel ^a,b   Higgins, Christopher F ^a   Sardini, Alessandro ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Cell swelling activated chloride current; Patch clamp; pH

Indexed keywords

4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; CALCIUM ION; CHLORIDE ION; EFENAMIC ACID; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; NIFLUMIC ACID; TAMOXIFEN;

ACIDIFICATION; ARTICLE; CELL CULTURE; CELL PH; CELL SWELLING; CELL VOLUME; CHLORIDE CURRENT; EMBRYO; HUMAN; HUMAN CELL; KIDNEY CELL; PATCH CLAMP; PRIORITY JOURNAL;

CELL LINE; CHLORIDE CHANNELS; CHLORIDES; EXTRACELLULAR FLUID; HUMANS; HYDROGEN-ION CONCENTRATION; MEMBRANE POTENTIALS; PATCH-CLAMP TECHNIQUES; SIGNAL TRANSDUCTION;

MAMMALIA;

EID: 6044248963     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00549.2002     Document Type: Article

References (48)

1. Alvarez-Leefmans FJ, Altamirano J, and Crowe WE. Use of ion-selective microelectrodes and fluorescent probes to measure cell volume. Methods Neurosci 27: 361-391, 1995.
2. Arreola J, Melvin JE, and Begenisich T. Volume-activated chloride channels in rat parotid acinar cells. J Physiol 484: 677-687, 1995.
3. Auzanneau C, Thoreau V, Kitzis A, and Becq F. A novel voltage-dependent chloride current activated by extracellular acidic pH in cultured rat Sertoli cells. J Biol Chem 278: 19230-19236, 2003.
4. Blaisdell CJ, Edmonds RD, Wang XT, Guggino S, and Zeitlin PL. pH-regulated chloride secretion in fetal lung epithelia. Am J Physiol Lung Cell Mol Physiol 278: L1248-L1255, 2000.
5. Bond TD, Valverde MA, and Higgins CF. Protein kinase C phosphorylation disengages human and mouse-1a P-glycoproteins from influencing the rate of activation of swelling-activated chloride currents. J Physiol 508: 333-340, 1998.
6. Callaghan R and Higgins CF. Interaction of tamoxifen with the multi-drug resistance P-glycoprotein. Br J Cancer 71: 294-299, 1995.
7. Cannon CL, Basavappa S, and Strange K. Intracellular ionic strength regulates the volume sensitivity of a swelling-activated anion channel. Am J Physiol Cell Physiol 275: C416-C422, 1998.
8. + of the muscle-type ClC chloride channels. J Gen Physiol 118: 23-32, 2001.
9. Diaz M, Valverde MA, Higgins CF, Rucareanu C, and Sepulveda FV. Volume-activated chloride channels in HeLa cells are blocked by verapamil and dideoxyforskolin. Pflügers Arch 422: 347-353, 1993.
10. Diewald L, Rupp J, Dreger M, Hucho F, Gillen C, and Nawrath H. Activation by acidic pH of CLC-7 expressed in oocytes from Xenopus laevis. Biochem Biophys Res Commun 291: 421-424, 2002.
11. Doroshenko P, Penner R, and Neher E. Novel chloride conductance in the membrane of bovine chromaffin cells activated by intracellular GTPγS. J Physiol 436: 711-724, 1991.
12. Duan D, Winter C, Cowley S, Hume JR, and Horowitz B. Molecular identification of a volume-regulated chloride channel. Nature 390: 417-421, 1997.
13. Dutzler R, Campbell EB, and MacKinnon R. Gating the selectivity filter in ClC chloride channels. Science 300: 108-112, 2003.
14. Gruenert DC, Basbaum CB, Welsh MJ, Li M, Finkbeiner WE, and Nadel JA. Characterization of human tracheal epithelial cells transformed by an origin-defective simian virus 40. Proc Natl Acad Sci USA 85: 5951-5955, 1988.
15. Hoffmann EK. Intracellular signalling involved in volume regulatory decrease. Cell Physiol Biochem 10: 273-288, 2000.
16. Hryciw DH and Guggino WB. Cystic fibrosis transmembrane conductance regulator and the outwardly rectifying chloride channel: a relationship between two chloride channels expressed in epithelial cells. Clin Exp Pharmacol Physiol 27: 892-895, 2000.
17. Iyer R, Iverson TM, Accardi A, and Miller C. A biological role for prokaryotic ClC chloride channels. Nature 419: 715-718, 2002.
18. Jakab M, Furst J, Gschwentner M, Botta G, Garavaglia ML, Bazzini C, Rodighiero S, Meyer G, Eichmueller S, Woll E, Chwatal S, Ritter M, and Paulmichl M. Mechanisms sensing and modulating signals arising from cell swelling. Cell Physiol Biochem 12: 235-258, 2002.
19. Jordt SE and Jentsch TJ. Molecular dissection of gating in the ClC-2 chloride channel. EMBO J 16: 1582-1592, 1997.
20. Kelly ME, Dixon SJ, and Sims SM. Outwardly rectifying chloride current in rabbit osteoclasts is activated by hyposmotic stimulation. J Physiol 475: 377-389, 1994.
21. - channels. Am J Physiol Cell Physiol 267: C642-C649, 1994.
22. - channel currents in cultured human epithelial cells. J Physiol 456: 351-371, 1992.
23. Landwojtowicz E, Nervi P, and Seelig A. Real-time monitoring of P-glycoprotein activation in living cells. Biochemistry 41: 8050-8057, 2002.
24. - channel. J Membr Biol 157: 63-69, 1997.
25. Mo L, Hellmich HL, Fong P, Wood T, Embesi J, and Wills NK. Comparison of amphibian and human ClC-5: similarity of functional properties and inhibition by external pH. J Membr Biol 168: 253-264, 1999.
26. - channels. Gen Pharmacol 27: 1131-1140, 1996.
27. Nilius B, Prenen J, and Droogmans G. Modulation of volume-regulated anion channels by extra- and intracellular pH. Pflügers Arch 436: 742-748, 1998.
28. Nilius B, Prenen J, Voets T, Eggermont J, and Droogmans G. Activation of volume-regulated chloride currents by reduction of intracellular ionic strength in bovine endothelial cells. J Physiol 506: 353-361, 1998.
29. - channel: fresh start to the molecular identity and volume sensor. Am J Physiol Cell Physiol 273: C755-C789, 1997.
30. Paulmichl M, Li Y, Wickman K, Ackerman M, Peralta E, and Clapham D. New mammalian chloride channel identified by expression cloning. Nature 356: 238-241, 1992.
31. Sabirov RZ, Prenen J, Droogmans G, and Nilius B. Extra- and intra-cellular proton-binding sites of volume-regulated anion channels. J Membr Biol 177: 13-22, 2000.
32. - channel in kidney distal tubule. Biochim Biophys Acta 1509: 73-85, 2000.
33. Schmid A, Blum R, and Krause E. Characterization of cell volume-sensitive chloride currents in freshly prepared and cultured pancreatic acinar cells from early postnatal rats. J Physiol 513: 453-465, 1998.
34. Shen DW, Fojo A, Chin JE, Roninson IB, Richert N, Pastan I, and Gottesman MM. Human multidrug-resistant cell lines: increased mdr1 expression can precede gene amplification. Science 232: 643-645, 1986.
35. Shi C, Ryan JS, French AS, Coca-Prados M, and Kelly ME. Hyposmotically activated chloride channels in cultured rabbit non-pigmented ciliary epithelial cells. J Physiol 521: 57-67, 1999.
36. Smets I, Ameloot M, Steels P, and Van Driessche W. Loss of cell volume regulation during metabolic inhibition in renal epithelial cells (A6): role of intracellular pH. Am J Physiol Cell Physiol 283: C535-C544, 2002.
37. Strange K, Emma F, and Jackson PS. Cellular and molecular physiology of volume-sensitive anion channels. Am J Physiol Cell Physiol 270: C711-C730, 1996.
38. - channel. Am J Physiol Cell Physiol 275: C1113-C1123, 1998.
39. Thiebaut F, Currier SJ, Whitaker J, Haugland RP, Gottesman MM, Pastan I, and Willingham MC. Activity of the multidrug transporter results in alkalinization of the cytosol: measurement of cytosolic pH by microinjection of a pH-sensitive dye. J Histochem Cytochem 38: 685-690, 1990.
40. Tinel H, Kinne-Saffran E, and Kinne RK. Calcium signalling during RVD of kidney cells. Cell Physiol Biochem 10: 297-302, 2000.
41. Valverde MA, Bond TD, Hardy SP, Taylor JC, Higgins CF, Altamirano J, and Alvarez-Leefmans FJ. The multidrug resistance P-glycoprotein modulates cell regulatory volume decrease. EMBO J 15: 4460-4468, 1996.
42. Valverde MA, Diaz M, Sepulveda FV, Gill DR, Hyde SC, and Higgins CF. Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein. Nature 355: 830-833, 1992.
43. - on three distinguishable chloride currents activated in T84 intestinal cells. Pflügers Arch 425: 552-554, 1993.
44. - current. J Gen Physiol 110: 313-325, 1997.
45. Voets T, Droogmans G, Raskin G, Eggermont J, and Nilius B. Reduced intracellular ionic strength as the initial trigger for activation of endothelial volume-regulated anion channels. Proc Natl Acad Sci USA 96: 5298-5303, 1999.
46. Weylandt KH, Valverde MA, Nobles M, Raguz S, Amey JS, Diaz M, Nastrucci C, Higgins CF, and Sardini A. Human ClC-3 is not the swelling-activated chloride channel involved in cell volume regulation. J Biol Chem 276: 17461-17467, 2001.
47. Yankaskas JR, Haizlip JE, Conrad M, Koval D, Lazarowski E, Paradiso AM, Rinehart CA Jr, Sarkadi B, Schlegel R, and Boucher RC. Papilloma virus immortalized tracheal epithelial cells retain a well-differentiated phenotype. Am J Physiol Cell Physiol 264: C1219-C1230, 1993.
48. Zhang J, Rasmusson RL, Hall SK, and Lieberman M. A chloride current associated with swelling of cultured chick heart cells. J Physiol 472: 801-820, 1993.