Identification of the pH sensor and activation by chemical modification of the ClC-2G Cl- channel

American Journal of Physiology - Cell Physiology

Volumn 275, Issue 4 44-4, 1998, Pages

  Stroffekova, Katarina ^a   Kupert, Elena Y ^a   Malinowska, Danuta H ^a   Cuppoletti, John ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Acid activated chloride channel; Amidation; Chloride transport; Cystic fibrosis; Epithelial transport; Gastric secretion; Human and rabbit chloride channels; Protein kinase A; Protein kinase regulated chloride channel; Water soluble carbodiimide; Xenopus laevis oocytes

Indexed keywords

CHLORIDE CHANNEL;

ANIMAL CELL; ARTICLE; HUMAN; NONHUMAN; PH MEASUREMENT; PRIORITY JOURNAL; RABBIT; SENSOR; STOMACH SECRETION; XENOPUS LAEVIS;

EID: 0031784387     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1998.275.4.c1113     Document Type: Article

References (26)

1. - channel. J. Gen. Physiol. 108: 237-250, 1996.
2. Cid, L. P., C. Montrose-Rafizadeh, D. I. Smith, W. B. Guiggino, and G. R. Cutting. Cloning of a putative human voltage-gated chloride channel (ClC-2) cDNA widely expressed in human tissues. Hum. Mol. Genet. 4: 407-413, 1995.
3. - channels of the gastric parietal cell that are active at low pH. Am. J. Physiol. 264 (Cell Physiol. 33): C1609-C1618, 1993.
4. Fahlke, C., A. Rosenbohm, N. Mitrovic, A. L. George, Jr., and R. Rüdel. Mechanism of voltage-dependent gating in skeletal muscle chloride channels. Biophys. J. 71: 695-706, 1996.
5. Fahlke, C., H. T. Yu, C. L. Beck, T. H. Rhodes, and A. L. George, Jr. Pore-forming segments in voltage-gated chloride channels. Nature 390: 529-532, 1997.
6. Fuller, C. M., B. K. Berdiev, V. G. Shlyonsky, I. I. Ismailov, and D. J. Benos. Point mutations in αβENaC regulate channel gating, ion selectivity and sensitivity to amiloride. Biophys. J. 72: 1622-1632, 1997.
7. Furukawa, T., S. Horikawa, T. Terai, T. Ogura, Y. Katayama, and M. Hiraoka. Molecular cloning and characterization of a novel truncated form (ClC-2β) of ClC-2α (ClC-2G) in rabbit heart. FEBS Lett. 375: 56-62 1995.
8. Furukawa, T., T. Ogura, Y. Katayama, and M. Hiraoka. Characteristics of rabbit ClC-2 current expressed in Xenopus oocytes and its contribution to volume regulation. Am. J. Physiol. 274 (Cell Physiol. 43): C500-C512, 1998.
9. Gründer, S., A. Thiemann, M. Pusch, and T. J. Jentsch. Regions involved in the opening of ClC-2 chloride channel by voltage and cell volume. Nature 360: 759-762, 1992.
10. Hille, B. Charges and potentials at the nerve surface: divalent ions and pH. J. Gen. Physiol. 51: 221-236, 1968.
11. Jentsch, T. J. Chloride channels: a molecular perspective. Curr. Opin. Neurobiol. 6: 303-310, 1996.
12. Jentsch, T. J., W. Günther, M. Pusch, and B. Schwappach. Properties of voltage-gated chloride channels of the ClC gene family. J. Physiol. (Lond.) 482: 19S-25S, 1995.
13. Jordt, S. E., and T. J. Jentsch. Molecular dissection of gating in the ClC-2 chloride channel. EMBO J. 16: 1582-1592, 1997.
14. Kieferle, S., P. Fong, M. Bens, A. Vandewalle, and T. J. Jentsh. Two highly homologous members of the ClC chloride channel family in both rat and human kidney. Proc. Natl. Acad. Sci. USA 91: 6943-6947, 1994.
15. Ludewig, U., M. Pusch, and T. J. Jentsch. Independent gating of single pores in CLC-0 chloride channels. Biophys. J. 73: 789-797, 1997.
16. - channel. Am. J. Physiol. 268 (Cell Physiol. 37): C191-C200, 1995.
17. Mathews, C. J., J. A. Tabcharani, X-B. Chang, T. J. Jensen, J. R. Riordan, and J. W. Hanrahan. Dibasic protein kinase A sites regulate bursting rate and nucleotide sensitivity of the cystic fibrosis transmembrane conductance regulator chloride channel. J. Physiol. (Lond.) 508: 365-377, 1998.
18. Means, G. E., and R. E. Feeney. Chemical Modification of Proteins. San Francisco, CA: Holden-Day, 1971, p. 144-148.
19. Middleton, R. E., D. J. Pheasant, and C. Miller. Purification, reconstitution, and subunit composition of a voltage-gated chloride channel from Torpedo electroplax. Biochemistry 33: 13189-13198, 1994.
20. Rychkov, G. Y., M. Pusch, D. St. J. Astill, M. L. Roberts, T. J. Jentsch and A. H. Bretag. Concentration and pH dependence of skeletal muscle chloride channel ClC-1. J. Physiol. (Lond.) 497. 2: 423-435, 1996.
21. Schmidt-Rose, T., and T. J. Jentsch. Transmembrane topology of a ClC chloride channel. Proc. Natl. Acad. Sci. USA 94: 7633-7638, 1997.
22. Schwiebert, E. M., L. P. Cid-Soto, D. Stafford, M. Carter, C. J. Blaisdell, P. L. Zeitlin, W. B. Guggino, and G. R. Cutting. Analysis of ClC-2 channels as an alternative pathway for chloride conduction in cystic fibrosis airway cells. Proc. Natl. Acad. Sci. USA 95: 3879-3884, 1998.
23. - channel. Am. J. Physiol. 273 (Cell Physiol. 42): C384-C393, 1997.
24. Thiemann, A., S. Gründer, M. Pusch, and T. J. Jentsch. A chloride channel widely expressed in epithelial and non-epithelial cells. Nature 356: 57-60, 1992.
25. Weast, R. C. The CRC Handbook of Chemistry and Physics (50th ed.). Cleveland, OH: The Chemical Rubber Company, 1970.
26. Zahradnikova, A., and I. Zahradnik. A minimal gating model for the cardiac calcium release channel. Biophys. J. 71: 2996-3012, 1996.