Different immunomodulatory effects associated with sub-micrometer particles in ambient air from rural, urban and industrial areas

Toxicology

Volumn 257, Issue 3, 2009, Pages 127-136

  Wichmann, Gunnar ^a,b   Franck, Ulrich ^b   Herbarth, Olf ^a,b   Rehwagen, Martina ^b   Dietz, Andreas ^a   Massolo, Laura ^c   Ronco, Alicia ^c   Müller, Andrea ^b  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b HELMHOLTZ CENTRE FOR ENVIRONMENTAL RESEARCH UFZ   (Germany)

^c FACULTAD DE CIENCIAS EXACTAS   (Argentina)

Author keywords

Hexane extract; Immune suppression; In vitro; Interferon gamma (IFN gamma); Interleukin 4 (IL 4); Lymphocytes; Ultrafine particles

Indexed keywords

DIMETHYL SULFOXIDE; GAMMA INTERFERON; HEXANE; INTERLEUKIN 4; PHYTOHEMAGGLUTININ; POLYCYCLIC AROMATIC HYDROCARBON;

AMBIENT AIR; ARGENTINA; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOMODULATION; IMMUNOREGULATION; INDUSTRIAL AREA; PARTICULATE MATTER; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; RURAL AREA; SOLVENT EXTRACTION; T LYMPHOCYTE; TH1 CELL; TH2 CELL; URBAN AREA;

AIR POLLUTANTS; AIR POLLUTANTS, OCCUPATIONAL; ARGENTINA; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; DUST; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNITY, CELLULAR; IMMUNOLOGIC FACTORS; INTERFERON-GAMMA; INTERLEUKIN-4; MONOCYTES; NANOPARTICLES; PARTICLE SIZE; PHYTOHEMAGGLUTININS; POLYCYCLIC HYDROCARBONS, AROMATIC; RURAL HEALTH; SPECTROMETRY, FLUORESCENCE; T-LYMPHOCYTES, HELPER-INDUCER; TETRAZOLIUM SALTS; THIAZOLES; URBAN HEALTH;

EID: 60349117239     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2008.12.024     Document Type: Article

References (57)

1. Archuleta M.M., Schieven G.L., Ledbetter J.A., Deanin G.G., and Burchiel S.W. 7,12-dimethylbenz[a]anthracene activates protein-tyrosine kinases Fyn and Lck in the HPB-ALL human T-cell line and increases tyrosine phosphorylation of phospholipase C-γ 1, formation of inositol 1,4,5-triphosphate, and mobilization of intracellular calcium. Proc. Natl. Acad. Sci. U.S.A. 90 (1993) 6105-6109
2. Barale R., Giromini L., Ghelardini G., Scapoli C., Loprieno N., Pala M., Valerio F., and Barrai I. Correlations between 15 polycyclic aromatic hydrocarbons (PAH) and the mutagenicity of the total PAH fraction in ambient air particles in La Spezia (Italy). Mutat. Res. 249 (1991) 227-241
3. Bauer M., Raabe F., and Metzner G. In vitro model for the measurement of pollutant-effects on IgE-production. Allergologie 19 (1996) 199-201
4. Beak S.O., Goldstone M.E., Kirk P.W.W., Lester J.N., and Perrry R. Phase distribution and particle size dependency of polycyclic aromatic hydrocarbons in the urban atmosphere. Chemosphere 22 (1991) 503-550
5. Becher H., Ramroth H., Ahrens W., Risch A., Schmezer P., and Dietz A. Occupation, exposure to polycyclic aromatic hydrocarbons and laryngeal cancer risk. Int. J. Cancer 16 (2005) 451-457
6. Benner J.R., Bruce A., Gorden G.E., and Wise S.A. Mobile sources of atmospheric polycyclic aromatic hydrocarbons: a roadway tunnel study. Environ. Sci. Technol. 23 (1989) 1269-1278
7. Bommel H., Li-Weber M., Serfling E., and Duschl A. The environmental pollutant pyrene induces the production of IL-4. J. Allergy Clin. Immunol. 105 (2000) 796-802
8. Brinkmann V., and Kinzel B. IL-4 and IL-13 in atopy: regulation of production and effects. In: Vercelli D. (Ed). IgE-regulation: Molecular Mechanisms (1997), John Wiley & Sons, Inc., Chichester/New York/Weinheim/Brisbane/Singapore/Toronto 75-101
9. 40 CFR, 1987 ed. 18O.1O1. (C), Part 261, Identification and Listing of Hazardous Haste.
10. Dietz A., Ramroth H., Urban T., Ahrens W., and Becher H. Exposure to cement dust, related occupational groups and laryngeal cancer risk: results of a population based case-control study. Int. J. Cancer 108 (2004) 907-911
11. Dietz A., Sennewald E., and Maier H. Indoor air pollution by emissions of fossil fuel-single stoves-possibly a hitherto underrated risk factor in the development of carcinomas in head and neck. Otolaryngol.-Head Neck Surg. 2 (1995) 308-315
12. Diez U., Kroessner T., Rehwagen M., Richter M., Wetzig H., Schulz R., Borte M., Metzner G., Krumbiegel P., and Herbarth O. Effect of indoor painting and smoking on airway symptoms in atopy risk children in the first year of life-results of the LARS-study. Int. J. Hyg. Environ. Health 203 (2000) 23-28
13. Dockery D.W., Schwarz J., and Spengler J.D. Air pollution and daily mortality: association with particles and acid aerosols. Environ. Res. 59 (1992) 362-373
14. Dybing E., Lovdal T., Hetland R.B., Lovik M., and Schwarze P.E. Respiratory allergy adjuvant and inflammatory effects of urban ambient particles. Toxicology 198 (2004) 307-314
15. Ferin J., Oberdörster G., and Penney D.P. Pulmonary retention of ultrafine and fine particles in rats. Am. J. Respir. Cell. Mol. Biol. 6 (1992) 535-542
16. Fritz G.J., and Herbarth O. Asthmatic disease among urban preschoolers: an observational study. Int. J. Hyg. Environ. Health 207 (2004) 23-30
17. Hauser R., Godleski J., Hatch V., and Christiani D.C. Ultrafine particles in human lung macrophages. Arch. Environ. Health 56 (2001) 150-156
18. Herbarth O., Fritz G., Krumbiegel P., Diez U., Franck U., and Richter M. Effect of sulphur dioxide and particulate pollutants on bronchitis in children-a risk analysis. Environ. Toxicol. 16 (2001) 269-276
19. Herbarth O., Fritz G.J., Rehwagen M., Richter M., Röder S., and Schlink U. Association between indoor renovation activities and eczema in early childhood. Int. J. Hyg. Environ. Health 209 (2006) 241-247
20. 2.5-10 ambient air pollutants assessed by the MTT and the Comet assays. Mutat. Res. 471 (2000) 45-55
21. IARC-International Agency for Research on Cancer. Monographs on the Evaluation of Carcinogenic Risk to Humans vol. 32 (1983)
22. IARC-International Agency for Research on Cancer. Monograph on the Evaluation of Carcinogenic Risk to Humans vol. 82 (2002) p. 367
23. Junker M., Kasper M., Röösli M., Camenzind M., Künzli N., Monn C., Theis G., and Braun-Fahrländer C. Airborne particle number profiles, particle mass distributions and particle-bound PAH concentrations within the city environment of Basel: an assessment as part of the BRISKA Project. Atmos. Environ. 34 (2000) 3171-3181
24. Kakimoto H., Matsumoto Y., Sakai S., Kanoh F., Arashidani K., Tang N., Akutso K., Nakajima A., Awata Y., Toriba A., Kizu R., and Hayakawa K. Comparison of atmospheric polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarbons in an industrialized city (Kitakyushu) and two commercial cities (Sapporo and Tokyo). J. Health Sci. 48 (2002) 370-375
25. Kawanaka Y., Matsumoto E., Sakamoto K., Wang N., and Yun S.J. Size distribution of mutagenic compounds and mutagenicity in atmospheric particulate matter collected with a low-pressure cascade impactor. Atmos. Environ. 38 (2004) 2125-2132
26. Kiss G., Varga-Punchony Z., Rohrbacher G., and Hlavay J. Distribution of polycyclic aromatic hydrocarbons on atmospheric aerosol particles of different sizes. Atmos. Res. 46 (1998) 253-261
27. Krieger J.A., Davila D.R., Lytton J., Born J.L., and Burchiel S.W. Inhibition of sarcoplasmic/endoplasmic reticulum calcium ATPases (SERCA) by polycyclic aromatic hydrocarbons in HPB-ALL human T cells and other tissues. Toxicol. Appl. Pharmacol. 133 (1995) 102-108
28. Lai Z.W., Hundeiker C., Gleichmann E., and Esser C. Cytokine gene expression during ontogeny in murine thymus on activation of the aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Mol. Pharmacol. 52 (1997) 30-37
29. Li C.K., and Kamens R.M. The use of polycyclic aromatic hydrocarbons as source signatures in receptor modelling. Atmos. Environ. 27 (1993) 523-532
30. Marple V.A., and Liu B.Y.H. Characteristics of Laminar Jet Impactors. Environ. Sci. Technol. 8 (1974) 648-654
31. Massolo L., Müller A., Tueros M., Rehwagen M., Franck U., Ronco A., and Herbarth O. Assessment of mutagenicity and toxicity of different size fractions of air particulates from La Plata, Argentina and Leipzig, Germany. Environ. Toxicol. 17 (2002) 219-231
32. Morgenstern V., Zutavern A., Cyrys J., Brockow I., Koletzko S., Kramer U., Behrendt H., Herbarth O., von Berg A., Bauer C.P., Wichmann H.E., Heinrich J., and Gini and Lisa Study Group. Atopic diseases, allergic sensitisation and exposure to traffic-related air pollution in children. Am. J. Respir. Crit. Care Med. 177 (2008) 1331-1337
33. Müller A., Alzuet P., Herbarth O., and Ronco A. Assessment of toxicity and mutagenicity in air particulate matter from an urban industrial area in the coast of the Rio de la Plata. Environ. Toxicol. 16 (2001) 151-157
34. Müller A., Wichmann G., Massolo L., Rehwagen M., Gräbsch C., Loffhagen N., Herbarth O., and Ronco A. Cytotoxicity and oxidative stress caused by chemicals adsorbed on particulate matter. Environ. Toxicol. 21 (2006) 457-463
35. Pierce R.C., and Katz M. Dependency of polynuclear aromatic hydrocarbons content on size distribution of atmospheric aerosols. Environ. Sci. Technol. 9 (1975) 347-353
36. Pries R., and Wollenberg B. Cytokines in head and neck cancer. Cytokine Growth Factor Rev. 17 (2006) 141-146
37. Rehwagen M., Müller A., Massolo L., Herbarth O., and Ronco A. Polycyclic aromatic hydrocarbons associated with particles in ambient air from urban and industrial areas. Sci. Total Environ. 348 (2005) 199-210
38. Romagnani S. Human Th1 and Th2 subsets: doubt no more. Immunol. Today 12 (1991) 256-257
39. Romagnani S. Development of Th 1- or Th 2- dominated immune responses: what about the polarizing signals?. Int. J. Clin. Lab. Res. 26 (1996) 83-98
40. Sauvain J.J., Vu Duc T., and Guillemin M. Exposure to carcinogenic polycyclic aromatic compounds and health risk assessment for diesel-exhaust exposed workers. Int. Arch. Occup. Environ. Health 76 (2003) 443-455
41. Schwartz J., and Neas L.M. Fine particles are more strongly associated than coarse particles with acute respiratory health effects in schoolchildren. Epidemiology 11 (2000) 6-10
42. Sheu H.L., Lee W.J., Lin S.J., Fang G.C., Chang H.C., and You W.C. Particle bound PAH content in ambient air. Environ. Pollut. 96 (1997) 369-382
43. Sirce M.A., Marty J.C., and Saliot A. Aliphatic and aromatic hydrocarbons in different size aerosols over the Mediterranean Sea: occurrence and origin. Atmos. Environ. 12 (1987) 2247-2259
44. Steerenberg P.A., Withagen C.E., Dormans J.A., van Dalen W.J., van Loveren H., and Casee F.R. Adjuvant activity of various diesel exhaust and ambient particles in two allergic models. J. Toxicol. Environ Health A 66 (2003) 1421-1439
45. Steerenberg P.A., Withagen C.E., van Dalen W.J., Dormans J.A., Cassee F.R., Heisterkamp S.H., and van Loveren H. Adjuvant activity of ambient particulate matter of different sites, sizes, and seasons in a respiratory allergy mouse model. Toxicol. Appl. Pharmacol. 200 (2004) 186-200
46. Takafuji S., Suzuki S., Koizumi K., Tadokoro K., Miyamoto T., and Ikemori R. Diesel exhaust particulates inoculated by the intranasal route have an adjuvant activity for IgE production in mice. J. Allergy Clin. Immunol. 79 (1987) 639-643
47. Takaki M. Environmental and immunological survey of sensitization with Japanese cedar cryptomeria-japonica pollen in children. I. Environmental factors influencing sensitization with Japanese cedar cryptomeria-japonica pollen among asthmatic children. Jpn. J. Allergol. 37 (1988) 1065-1071
48. Takenaka H., Zhang K., Diaz-Sanches D., Tsien A., and Saxon A. Enhanced human IgE production results from exposure to the aromatic hydrocarbons from diesel exhaust: direct effects on B-cell IgE production. J. Allergy Clin. Immunol. 95 (1995) 103-115
49. Tuominen J., Salomaa S., Pysalo H., Skyttä E., Tikkanen L., Nurmale T., Sorsa M., Pohjola V., Sauri M., and Himberg K. Polynuclear aromatic compounds and genotoxicity in particulate and vapour phases of ambient air: effect of traffic, season, and meteorological conditions. Environ. Sci. Technol. 22 (1988) 1228-1234
50. US EPA, 1996a. US EPA, Air Quality Criteria for Particulate Matter EPA/600/P-95/00 1cF, vol. 3. U.S. Environmental Protection Agency Office of Research and Development, Washington, DC.
51. US EPA, 1996b. US EPA, Review of the National Ambient Air Quality Standards for Particulate Matter: Policy Assessment of Scientific and Technical Information OAQPS Staff Paper EPA-452/R-96-013 Office of Air Quality Planning and Standards. U.S. Environmental Protection Agency Research, Triangle Park, NC.
52. Venkataraman C., Lyons J.M., and Fiedlander S. Size distribution of aromatic hydrocarbons and elemental carbon, sampling measurement methods and source characterization. Environ. Sci. Technol. 28 (1994) 535-562
53. Westerholm R., Stenberg U., and Alsberg T. Some aspects of the distribution of polycyclic aromatic hydrocarbons (PAH) between particles and gas phase from diluted gasoline exhausts generated with the use of a dilution tunnel and its validity for measurement in ambient air. Atmos. Environ. 22 (1988) 1005-1010
54. Wichmann G., Metzner G., and Raabe F. Modulation der In vitro-Zytokinproduktion durch aromatische Kohlenwasserstoffe: Hinweise auf eine Beteiligung von Umweltschadstoffen an der Allergieentstehung. Allergologie 22 (1999) 101-107
55. Wichmann G., Daegelmann C., Herbarth O., Strauch G., Schirmer K., Wostemeyer J., and Lehmann I. Inflammatory activity in river-water samples. Environ. Toxicol. 19 (2004) 594-602
56. [WHO] World Health Organization. Guidelines for air quality. Health-based Guidelines (2000), WHO, Geneva, Switzerland pp. 32-71 (Chapter 3)
57. Zwozdzdiak J., Jadzyk P., and Kucharczyk J. Seasonal variability of the mutagenicity of airborne particles in the town center. Aerosol Sci. 32 (2001) 409-423