Modulation of in vitro cytokine production by aromatic hydrocarbons;Modulation der in-vitro-zytokinproduktion durch aromatische kohlenwasserstoffe

Allergologie

Volumn 22, Issue 2, 1999, Pages 101-107

  Wichmann, G ^a   Raabe, F ^b   Metzner, G ^b  

^a UNIVERSITY HOSPITAL LEIPZIG   (Germany)

^b NONE

Author keywords

Allergy development; Cytokines; Environmental pollutants; In vitro; Th2 cells

Indexed keywords

1 FLUORO 2,4 DINITROBENZENE; 1,4 BENZOQUINONE; 7,12 DIMETHYLBENZ[A]ANTHRACENE; ANTHRACENE; AROMATIC HYDROCARBON; BENZO[A]PYRENE; CYTOKINE; DIBENZ[A,H]ANTHRACENE; GAMMA INTERFERON; IMMUNOGLOBULIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; TUMOR NECROSIS FACTOR;

ALLERGY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; IMMUNOMODULATION; IN VITRO STUDY; MONONUCLEAR CELL; POLLUTION;

EID: 0033037815     PISSN: 03445062     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Archuleta M.M., G.L. Schieven, J.A. Ledbetter, G.G. Deanin, S.W. Burchiel: 7,12-dimethylbenz[a]anthracene activates protein-tyrosine kinases Fyn and Lck in the HPB-ALL human T-cell line and increases tyrosine phosphorylation of phospholipase C-gamma 1, formation of inositol 1,4,5-triphosphate, and mobilization of intracellular calcium. Proc. Natl. Acad. Sci. USA 90, 6105-6109 (1993).
2. Bauer M., F. Raabe, G. Metzner: In-vitro-Modell zur Messung von Schadstoffeinflüssen auf die IgE-Produktion. Allergologie 19, 199-201 (1996).
3. Brinkmann V., B. Kinze: IL-4 and IL-13 in atopy: regulation of production and effects. In: Vercelli D.: IgE-regulation: molecular mechanisms. Jon Wiley & Sons, Inc., Chichester 1997, 75-101.
4. Darnell J.E. jr., I.M. Kerr, G.R. Stark: Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264, 1415-1421 (1994).
5. d mice is mediated by interferon-gamma (IFNγ). Clin. Exp. Immunol. 109, 149-156 (1997).
6. Gibbons J.A., J.G. Babish: Benzo[e]pyrene elicits changes in the biochemical activities and chromatographic behavior of murine hepatic cytochromes P-450 that are distinct from those induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Chem. Biol. Interact. 83, 203-220 (1992).
7. Kramer C.M., K.W. Johnson, R.K. Dooley, M.P. Holsapple: 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) enhances antibody production and protein kinase activity in murine B cells. Biochem. Biophys. Res. Comm. 145, 25-33 (1987).
8. Krieger J A., D.R. Davila, J. Lytton, J.L. Born, S.W. Burchiel: Inhibition of sarcoplasmic/endoplasmic reticulum calcium ATPases (SERCA) by polycyclic aromatic hydrocarbons in HPB-ALL human T cells and other tissues. Toxicol. Appl. Pharmacol. 133, 102-108 (1995).
9. Lai Z.W., C. Hundziker, E. Gleichmann, C. Esser: Cytokine gene expression during ontogeny in murine thymus on activation of the aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Mol. Pharmacol. 52, 30-37 (1997).
10. Nakashima I., M.Y. Pu, A. Nishizaki, I. Rosila, L. Ma, Y. Katano, K. Ohkusu, S.M. Rahman, K. Isobe, M. Hamaguchi: Redox mechanism as alternative to ligand binding for receptor activation delivering disregulated cellular signals. J. Immunol. 152, 1064-1071 (1994).
11. Reichel M., B.H. Nelson, P.D. Greenberg, P.B. Rothman: The IL-4 receptor α-chain cytoplasmatic domain is sufficient for activation of JAK-1 and STAT6 and the induction of IL-4 specific gene expression. J. Immunol. 158, 5860-5867 (1997).
12. Sulentic C.E., M.P. Holsapple, N.E. Kaminski: Aryl hydrocarbon receptor-dependent suppression by 2,3,7,8-tetrachlorodibenzo-p-dioxin of IgM secretion in activated B cells. Mol. Pharmacol. 53, 623-629 (1998).
13. Sutter T.R., K. Guzman, K.M. Dold, W.F. Greenlee: Targets for dioxin: genes for plasminogen activator inhibitor-2 and interleukin-1β. Science 254, 415-418 (1991).
14. Takafuji S., S. Suzuki, K. Koizumi, K. Tadokoro, T. Miyamoto, R. Ikemori, M. Muranaka: Diesel exhaust particulates inoculated by the intranasal route have an adjuvant activity for IgE production in mice. J. Allergy Clin. Immunol. 79, 639-643 (1987).
15. Takenaka H., K. Zhang, D. Diaz-Sanches, A. Tsien, A. Saxon: Enhanced human IgE production results from exposure to the aromatic hydrocarbons from diesel exhaust: direct effects on B-cell IgE production. J. Allergy Clin. Immunol. 95, 103-115 (1995).
16. Vercelli D., H.H. Jabara, R.P. Lauener, R.S. Geha: IL-4 inhibits the synthesis of IFN-γ and induces the synthesis of IgE in human mixed lymphocyte cultures. J. Immunol. 144, 570-573 (1990).