Telmisartan, an angiotensin II type 1 receptor blocker, prevents the development of diabetes in male Spontaneously Diabetic Torii rats

European Journal of Pharmacology

Volumn 605, Issue 1-3, 2009, Pages 164-169

  Hasegawa, Goji ^a   Fukui, Michiaki ^a   Hosoda, Hiroko ^a   Asano, Mai ^a   Harusato, Ichiko ^a   Tanaka, Muhei ^a   Shiraishi, Emi ^a   Senmaru, Takashi ^a   Sakabe, Kazumi ^a   Yamasaki, Masahiro ^a   Kitawaki, Jo ^a   Fujinami, Aya ^b   Ohta, Mitsuhiro ^b   Obayashi, Hiroshi ^c   Nakamura, Naoto ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

^c Institute of Bio Response Informatics   (Japan)

Author keywords

Angiotensin II type 1 receptor blocker; Islet cell; NAD(P)H oxidase component; Oxidative stress; Renin angiotensin system; Spontaneously Diabetic Torii (SDT) (Rat); Type 2 diabetes mellitus

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GLYCOPROTEIN GP 91; MESSENGER RNA; PROTEIN P22; PROTEIN P47; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TELMISARTAN; TRANSFORMING GROWTH FACTOR BETA1; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DOSE RESPONSE; DRUG MEGADOSE; GENE EXPRESSION; HYPERGLYCEMIA; HYPOINSULINEMIA; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PANCREAS INSUFFICIENCY; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RAT STRAIN; REAL TIME POLYMERASE CHAIN REACTION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TREATMENT RESPONSE; WESTERN BLOTTING;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; BENZIMIDAZOLES; BENZOATES; BLOTTING, WESTERN; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; INSULIN-SECRETING CELLS; MALE; NADPH OXIDASE; OXIDATIVE STRESS; PANCREAS; RATS; RENIN-ANGIOTENSIN SYSTEM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 60349107760     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2009.01.001     Document Type: Article

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