Partial denervation of ankle extensors prior to spinalization in cats impacts the expression of locomotion and the phasic modulation of reflexes

Neuroscience

Volumn 158, Issue 4, 2009, Pages 1675-1690

  Frigon, A ^a   Rossignol, S ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

denervation; locomotion; plasticity; reflex; spinalization

Indexed keywords

CLONIDINE;

ANIMAL EXPERIMENT; ANKLE; ARTICLE; CONTROLLED STUDY; ELECTROMYOGRAPHY; EXPERIMENTAL CAT; EXTENSOR MUSCLE; GASTROCNEMIUS MUSCLE; KINEMATICS; LEG MUSCLE; LOCOMOTION; MUSCLE DENERVATION; NERVE STIMULATION; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; SOLEUS MUSCLE; SPINAL REFLEX; SPINE; TIBIAL NERVE; TREADMILL;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; ANKLE; BIOMECHANICS; CATS; ELECTROMYOGRAPHY; EXERCISE TEST; FEMALE; HINDLIMB; LOCOMOTION; MALE; MUSCLE DENERVATION; MUSCLE, SKELETAL; PHYSICAL CONDITIONING, ANIMAL; REFLEX; SPINAL CORD INJURIES; TIME FACTORS;

EID: 60349103847     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2008.11.005     Document Type: Article

References (37)

1. Abraham L.D., Marks W.B., and Loeb G.E. The distal hindlimb musculature of the cat. Cutaneous reflexes during locomotion. Exp Brain Res 58 (1985) 594-603
2. Barbeau H., Julien C., and Rossignol S. The effects of clonidine and yohimbine on locomotion and cutaneous reflexes in the adult chronic spinal cat. Brain Res 437 (1987) 83-96
3. Barbeau H., and Rossignol S. Recovery of locomotion after chronic spinalization in the adult cat. Brain Res 412 (1987) 84-95
4. Barriere G., Leblond H., Provencher J., and Rossignol S. Prominent role of the spinal central pattern generator in the recovery of locomotion after partial spinal cord injuries. J Neurosci 28 (2008) 3976-3987
5. Bélanger M., Drew T., Provencher J., and Rossignol S. A comparison of treadmill locomotion in adult cats before and after spinal transection. J Neurophysiol 76 (1996) 471-491
6. Bernard G., Bouyer L., Provencher J., and Rossignol S. Study of cutaneous reflex compensation during locomotion after nerve section in the cat. J Neurophysiol 97 (2007) 4173-4185
7. Bouyer L.J.G., and Rossignol S. Contribution of cutaneous inputs from the hindpaw to the control of locomotion: 2. Spinal cats. J Neurophysiol 90 (2003) 3640-3653
8. Bouyer L.J.G., Whelan P., Pearson K.G., and Rossignol S. Adaptive locomotor plasticity in chronic spinal cats after ankle extensors neurectomy. J Neurosci 21 (2001) 3531-3541
9. Bretzner F., and Drew T. Changes in corticospinal efficacy contribute to the locomotor plasticity observed following unilateral cutaneous denervation of the hindpaw in the cat. J Neurophysiol 94 (2005) 2911-2927
10. Carrier L., Brustein L., and Rossignol S. Locomotion of the hindlimbs after neurectomy of ankle flexors in intact and spinal cats: model for the study of locomotor plasticity. J Neurophysiol 77 (1997) 1979-1993
11. Chau C., Barbeau H., and Rossignol S. Early locomotor training with clonidine in spinal cats. J Neurophysiol 79 (1998) 392-409
12. Chen X.Y., Carp J.S., Chen L., and Wolpaw J.R. Corticospinal tract transection prevents operantly conditioned H-reflex increase in rats. Exp Brain Res 144 (2002) 88-94
13. Chen X.Y., Chen L., and Wolpaw J.R. Conditioned H-reflex increase persists after transection of the main corticospinal tract in rats. J Neurophysiol 90 (2003) 3572-3578
14. Drew T., and Rossignol S. Forelimb responses to cutaneous nerve stimulation during locomotion in intact cats. Brain Res 329 (1985) 323-328
15. Duysens J., and Stein R.B. Reflexes induced by nerve stimulation in walking cats with implanted cuff electrodes. Exp Brain Res 32 (1978) 213-224
16. Frigon A., and Rossignol S. Experiments and models of sensorimotor interactions during locomotion. Biol Cybern 95 (2006) 607-627
17. Frigon A., and Rossignol S. Plasticity of reflexes from the foot during locomotion after denervating ankle extensors in intact cats. J Neurophysiol 98 (2007) 2122-2132
18. Frigon A., and Rossignol S. Adaptive changes of the locomotor pattern and cutaneous reflexes during locomotion studied in the same cats before and after spinalization. J Physiol 586 (2008) 2927-2945
19. Frigon A., and Rossignol S. Locomotor and reflex adaptation after partial denervation of ankle extensors in chronic spinal cats. J Neurophysiol 100 (2008) 1513-1522
20. Frigon A., and Rossignol S. Short-latency crossed inhibitory responses in extensor muscles during locomotion in the cat. J Neurophysiol 99 (2008) 989-998
21. Julien C., and Rossignol S. Electroneurographic recordings with polymer cuff electrodes in paralyzed cats. J Neurosci Methods 5 (1982) 267-272
22. Loeb G.E. The distal hindlimb musculature of the cat: interanimal variability of locomotor activity and cutaneous reflexes. Exp Brain Res 96 (1993) 125-140
23. Marder E., and Goaillard J.M. Variability, compensation and homeostasis in neuron and network function. Nat Rev Neurosci 7 (2006) 563-574
24. Matthews P.B. Observations on the automatic compensation of reflex gain on varying the pre-existing level of motor discharge in man. J Physiol 374 (1986) 73-90
25. Pearson K.G. Role of sensory feedback in the control of stance duration in walking cats. Brain Res Rev 57 (2008) 222-227
26. Pearson K.G., Fouad K., and Misiaszek J.E. Adaptive changes in motor activity associated with functional recovery following muscle denervation in walking cats. J Neurophysiol 82 (1999) 370-381
27. Pearson K.G., and Rossignol S. Fictive motor patterns in chronic spinal cats. J Neurophysiol 66 (1991) 1874-1887
28. Pratt C.A., Chanaud C.M., and Loeb G.E. Functionally complex muscles of the cat hindlimb. IV. Intramuscular distribution of movement command signals and cutaneous reflexes in broad, bifunctional thigh muscles. Exp Brain Res 85 (1991) 281-299
29. Rossignol S. Plasticity of connections underlying locomotor recovery after central and/or peripheral lesions in the adult mammals. Phil Trans R Soc B 361 (2006) 1647-1671
30. Rossignol S., Barriere G., Frigon A., Barthelemy D., Bouyer L., Provencher J., Leblond H., and Bernard G. Plasticity of locomotor sensorimotor interactions after peripheral and/or spinal lesions. Brain Res Rev 57 (2008) 228-240
31. Rossignol S., Dubuc R., and Gossard J.P. Dynamic sensorimotor interactions in locomotion. Physiol Rev 86 (2006) 89-154
32. Rossignol S., Schwab M., Schwartz M., and Fehlings M.G. Spinal cord injury: time to move?. J Neurosci 27 (2007) 11782-11792
33. Whelan P.J., Hiebert G.W., and Pearson K.G. Plasticity of the extensor group I pathway controlling the stance to swing transition in the cat. J Neurophysiol 74 (1995) 2782-2787
34. Whelan P.J., and Pearson K.G. Plasticity in reflex pathways controlling stepping in the cat. J Neurophysiol 78 (1997) 1643-1650
35. Wolpaw J.R., and Lee C.L. Memory traces in primate spinal cord produced by operant conditioning of H-reflex. J Neurophysiol 61 (1989) 563-572
36. Zehr E.P., Komiyama T., and Stein R.B. Cutaneous reflexes during human gait: electromyographic and kinematic responses to electrical stimulation. J Neurophysiol 77 (1997) 3311-3325
37. Zehr E.P., and Stein R.B. What functions do reflexes serve during human locomotion?. Prog Neurobiol 58 (1999) 185-205