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Volumn 385, Issue 1, 2009, Pages 261-266

EBV LMP-2A employs a novel mechanism to transactivate the HERV-K18 superantigen through its ITAM

Author keywords

EBV; HERV; ITAM; LMP 2A; Superantigen; Transcription

Indexed keywords

BREAKPOINT CLUSTER REGION PROTEIN; IMMUNORECEPTOR TYROSINE BASED ACTIVATION MOTIF; LATENT MEMBRANE PROTEIN 2; SUPERANTIGEN; TYROSINE DERIVATIVE; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN;

EID: 60349094880     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2008.11.025     Document Type: Article
Times cited : (42)

References (35)
  • 1
    • 5144227841 scopus 로고    scopus 로고
    • Retroelements and the human genome: new perspectives on an old relation
    • Bannert N., and Kurth R. Retroelements and the human genome: new perspectives on an old relation. Proc. Natl. Acad. Sci. U. S. A. 101 Suppl 2 (2004) 14572-14579
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , Issue.SUPPL. 2 , pp. 14572-14579
    • Bannert, N.1    Kurth, R.2
  • 2
    • 33645522272 scopus 로고    scopus 로고
    • Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans
    • Barbulescu M., Turner G., Seaman M.I., Deinard A.S., Kidd K.K., and Lenz J. Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans. Curr. Biol. 9 16 (1999) 861-868
    • (1999) Curr. Biol. , vol.9 , Issue.16 , pp. 861-868
    • Barbulescu, M.1    Turner, G.2    Seaman, M.I.3    Deinard, A.S.4    Kidd, K.K.5    Lenz, J.6
  • 3
    • 0027453549 scopus 로고
    • The (YXXL/I)2 signalling motif found in the cytoplasmic segments of the bovine leukaemia virus envelope protein and Epstein-Barr virus latent membrane protein 2A can elicit early and late lymphocyte activation events
    • Beaufils P., Choquet D., Mamoun R.Z., and Malissen B. The (YXXL/I)2 signalling motif found in the cytoplasmic segments of the bovine leukaemia virus envelope protein and Epstein-Barr virus latent membrane protein 2A can elicit early and late lymphocyte activation events. EMBO. J. 12 13 (1993) 5105-5112
    • (1993) EMBO. J. , vol.12 , Issue.13 , pp. 5105-5112
    • Beaufils, P.1    Choquet, D.2    Mamoun, R.Z.3    Malissen, B.4
  • 4
    • 0028090058 scopus 로고
    • Interactions of Lyn with the antigen receptor during B cell activation
    • Burg D.L., Furlong M.T., Harrison M.L., and Geahlen R.L. Interactions of Lyn with the antigen receptor during B cell activation. J. Biol. Chem. 269 45 (1994) 28136-28142
    • (1994) J. Biol. Chem. , vol.269 , Issue.45 , pp. 28136-28142
    • Burg, D.L.1    Furlong, M.T.2    Harrison, M.L.3    Geahlen, R.L.4
  • 5
    • 0025739498 scopus 로고
    • Anti-immunoglobulin stimulation of B lymphocytes activates src-related protein-tyrosine kinases
    • Burkhardt A.L., Brunswick M., Bolen J.B., and Mond J.J. Anti-immunoglobulin stimulation of B lymphocytes activates src-related protein-tyrosine kinases. Proc. Natl. Acad. Sci. U. S. A. 88 16 (1991) 7410-7414
    • (1991) Proc. Natl. Acad. Sci. U. S. A. , vol.88 , Issue.16 , pp. 7410-7414
    • Burkhardt, A.L.1    Brunswick, M.2    Bolen, J.B.3    Mond, J.J.4
  • 6
    • 0000722327 scopus 로고
    • New nomenclature for the Reth motif (or ARH1/TAM/ARAM/YXXL)
    • Cambier J.C. New nomenclature for the Reth motif (or ARH1/TAM/ARAM/YXXL). Immunol. Today 16 2 (1995) 110
    • (1995) Immunol. Today , vol.16 , Issue.2 , pp. 110
    • Cambier, J.C.1
  • 7
    • 0032735122 scopus 로고    scopus 로고
    • Germ cell expression of an isolated human endogenous retroviral long terminal repeat of the HERV-K/HTDV family in transgenic mice
    • Casau A.E., Vaughan J.E., Lozano G., and Levine A.J. Germ cell expression of an isolated human endogenous retroviral long terminal repeat of the HERV-K/HTDV family in transgenic mice. J. Virol. 73 12 (1999) 9976-9983
    • (1999) J. Virol. , vol.73 , Issue.12 , pp. 9976-9983
    • Casau, A.E.1    Vaughan, J.E.2    Lozano, G.3    Levine, A.J.4
  • 8
    • 0034724652 scopus 로고    scopus 로고
    • Solitary HERV-K LTRs possess bi-directional promoter activity and contain a negative regulatory element in the U5 region
    • Domansky A.N., Kopantzev E.P., Snezhkov E.V., Lebedev Y.B., Leib-Mosch C., and Sverdlov E.D. Solitary HERV-K LTRs possess bi-directional promoter activity and contain a negative regulatory element in the U5 region. FEBS Lett. 472 2-3 (2000) 191-195
    • (2000) FEBS Lett. , vol.472 , Issue.2-3 , pp. 191-195
    • Domansky, A.N.1    Kopantzev, E.P.2    Snezhkov, E.V.3    Lebedev, Y.B.4    Leib-Mosch, C.5    Sverdlov, E.D.6
  • 9
    • 0030754766 scopus 로고    scopus 로고
    • The immunoreceptor tyrosine-based activation motif of Epstein-Barr virus LMP2A is essential for blocking BCR-mediated signal transduction
    • Fruehling S., and Longnecker R. The immunoreceptor tyrosine-based activation motif of Epstein-Barr virus LMP2A is essential for blocking BCR-mediated signal transduction. Virology 235 2 (1997) 241-251
    • (1997) Virology , vol.235 , Issue.2 , pp. 241-251
    • Fruehling, S.1    Longnecker, R.2
  • 10
    • 0031661310 scopus 로고    scopus 로고
    • Tyrosine 112 of latent membrane protein 2A is essential for protein tyrosine kinase loading and regulation of Epstein-Barr virus latency
    • Fruehling S., Swart R., Dolwick K.M., Kremmer E., and Longnecker R. Tyrosine 112 of latent membrane protein 2A is essential for protein tyrosine kinase loading and regulation of Epstein-Barr virus latency. J. Virol. 72 10 (1998) 7796-7806
    • (1998) J. Virol. , vol.72 , Issue.10 , pp. 7796-7806
    • Fruehling, S.1    Swart, R.2    Dolwick, K.M.3    Kremmer, E.4    Longnecker, R.5
  • 11
    • 0033519427 scopus 로고    scopus 로고
    • Immunoreceptor tyrosine-based inhibition motif-bearing receptors regulate the immunoreceptor tyrosine-based activation motif-induced activation of immune competent cells
    • Gergely J., Pecht I., and Sarmay G. Immunoreceptor tyrosine-based inhibition motif-bearing receptors regulate the immunoreceptor tyrosine-based activation motif-induced activation of immune competent cells. Immunol. Lett. 68 1 (1999) 3-15
    • (1999) Immunol. Lett. , vol.68 , Issue.1 , pp. 3-15
    • Gergely, J.1    Pecht, I.2    Sarmay, G.3
  • 12
    • 0032832548 scopus 로고    scopus 로고
    • Isolation and localization of an IDDMK1,2-22-related human endogenous retroviral gene, and identification of a CA repeat marker at its locus
    • Hasuike S., Miura K., Miyoshi O., Miyamoto T., Niikawa N., Jinno Y., and Ishikawa M. Isolation and localization of an IDDMK1,2-22-related human endogenous retroviral gene, and identification of a CA repeat marker at its locus. J. Hum. Genet. 44 5 (1999) 343-347
    • (1999) J. Hum. Genet. , vol.44 , Issue.5 , pp. 343-347
    • Hasuike, S.1    Miura, K.2    Miyoshi, O.3    Miyamoto, T.4    Niikawa, N.5    Jinno, Y.6    Ishikawa, M.7
  • 13
    • 33746930636 scopus 로고    scopus 로고
    • Cutting edge: Epstein-Barr virus transactivates the HERV-K18 superantigen by docking to the human complement receptor 2 (CD21) on primary B cells
    • Hsiao F.C., Lin M., Tai A., Chen G., and Huber B.T. Cutting edge: Epstein-Barr virus transactivates the HERV-K18 superantigen by docking to the human complement receptor 2 (CD21) on primary B cells. J. Immunol. 177 4 (2006) 2056-2060
    • (2006) J. Immunol. , vol.177 , Issue.4 , pp. 2056-2060
    • Hsiao, F.C.1    Lin, M.2    Tai, A.3    Chen, G.4    Huber, B.T.5
  • 14
    • 0031818334 scopus 로고    scopus 로고
    • ITAMs: immunoregulatory scaffolds that link immunoreceptors to their intracellular signaling pathways
    • Isakov N. ITAMs: immunoregulatory scaffolds that link immunoreceptors to their intracellular signaling pathways. Recept. Channels 5 5 (1998) 243-253
    • (1998) Recept. Channels , vol.5 , Issue.5 , pp. 243-253
    • Isakov, N.1
  • 15
    • 0024366793 scopus 로고
    • Production of multiple lymphokines by the A20.1 B cell lymphoma after cross-linking of membrane Ig by immobilized anti-Ig
    • Justement L.B., Kreiger J., and Cambier J.C. Production of multiple lymphokines by the A20.1 B cell lymphoma after cross-linking of membrane Ig by immobilized anti-Ig. J. Immunol. 143 3 (1989) 881-889
    • (1989) J. Immunol. , vol.143 , Issue.3 , pp. 881-889
    • Justement, L.B.1    Kreiger, J.2    Cambier, J.C.3
  • 16
    • 0028829921 scopus 로고
    • Characterization of the CD48 gene demonstrates a positive element that is specific to Epstein-Barr virus-immortalized B-cell lines and contains an essential NF-kappa B site
    • Klaman L.D., and Thorley-Lawson D.A. Characterization of the CD48 gene demonstrates a positive element that is specific to Epstein-Barr virus-immortalized B-cell lines and contains an essential NF-kappa B site. J. Virol. 69 2 (1995) 871-881
    • (1995) J. Virol. , vol.69 , Issue.2 , pp. 871-881
    • Klaman, L.D.1    Thorley-Lawson, D.A.2
  • 17
    • 0033010661 scopus 로고    scopus 로고
    • Genetic analysis of B cell antigen receptor signaling
    • Kurosaki T. Genetic analysis of B cell antigen receptor signaling. Annu. Rev. Immunol. 17 (1999) 555-592
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 555-592
    • Kurosaki, T.1
  • 18
    • 0028783396 scopus 로고
    • Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling
    • Kurosaki T., Johnson S.A., Pao L., Sada K., Yamamura H., and Cambier J.C. Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling. J. Exp. Med. 182 6 (1995) 1815-1823
    • (1995) J. Exp. Med. , vol.182 , Issue.6 , pp. 1815-1823
    • Kurosaki, T.1    Johnson, S.A.2    Pao, L.3    Sada, K.4    Yamamura, H.5    Cambier, J.C.6
  • 19
    • 27344434861 scopus 로고    scopus 로고
    • Transcriptional activation by bidirectional RNA polymerase II elongation over a silent promoter
    • Leupin O., Attanasio C., Marguerat S., Tapernoux M., Antonarakis S.E., and Conrad B. Transcriptional activation by bidirectional RNA polymerase II elongation over a silent promoter. EMBO Rep. 6 10 (2005) 956-960
    • (2005) EMBO Rep. , vol.6 , Issue.10 , pp. 956-960
    • Leupin, O.1    Attanasio, C.2    Marguerat, S.3    Tapernoux, M.4    Antonarakis, S.E.5    Conrad, B.6
  • 20
    • 0025915585 scopus 로고
    • An Epstein-Barr virus protein associated with cell growth transformation interacts with a tyrosine kinase
    • Longnecker R., Druker B., Roberts T.M., and Kieff E. An Epstein-Barr virus protein associated with cell growth transformation interacts with a tyrosine kinase. J. Virol. 65 7 (1991) 3681-3692
    • (1991) J. Virol. , vol.65 , Issue.7 , pp. 3681-3692
    • Longnecker, R.1    Druker, B.2    Roberts, T.M.3    Kieff, E.4
  • 21
    • 33646847002 scopus 로고    scopus 로고
    • Syk tyrosine kinase mediates Epstein-Barr virus latent membrane protein 2A-induced cell migration in epithelial cells
    • Lu J., Lin W.H., Chen S.Y., Longnecker R., Tsai S.C., Chen C.L., and Tsai C.H. Syk tyrosine kinase mediates Epstein-Barr virus latent membrane protein 2A-induced cell migration in epithelial cells. J. Biol. Chem. 281 13 (2006) 8806-8814
    • (2006) J. Biol. Chem. , vol.281 , Issue.13 , pp. 8806-8814
    • Lu, J.1    Lin, W.H.2    Chen, S.Y.3    Longnecker, R.4    Tsai, S.C.5    Chen, C.L.6    Tsai, C.H.7
  • 22
    • 0025367679 scopus 로고
    • The staphylococcal enterotoxins and their relatives
    • Marrack P., and Kappler J. The staphylococcal enterotoxins and their relatives. Science 248 4959 (1990) 1066
    • (1990) Science , vol.248 , Issue.4959 , pp. 1066
    • Marrack, P.1    Kappler, J.2
  • 23
    • 0034761377 scopus 로고    scopus 로고
    • C-terminal domain of the Epstein-Barr virus LMP2A membrane protein contains a clustering signal
    • Matskova L., Ernberg I., Pawson T., and Winberg G. C-terminal domain of the Epstein-Barr virus LMP2A membrane protein contains a clustering signal. J. Virol. 75 22 (2001) 10941-10949
    • (2001) J. Virol. , vol.75 , Issue.22 , pp. 10941-10949
    • Matskova, L.1    Ernberg, I.2    Pawson, T.3    Winberg, G.4
  • 24
    • 33645310982 scopus 로고    scopus 로고
    • ITAM-mediated tonic signalling through pre-BCR and BCR complexes
    • Monroe J.G. ITAM-mediated tonic signalling through pre-BCR and BCR complexes. Nat. Rev. Immunol. 6 4 (2006) 283-294
    • (2006) Nat. Rev. Immunol. , vol.6 , Issue.4 , pp. 283-294
    • Monroe, J.G.1
  • 26
    • 0036866477 scopus 로고    scopus 로고
    • Amplification of B cell antigen receptor signaling by a Syk/ITAM positive feedback loop
    • Rolli V., Gallwitz M., Wossning T., Flemming A., Schamel W.W., Zurn C., and Reth M. Amplification of B cell antigen receptor signaling by a Syk/ITAM positive feedback loop. Mol. Cell 10 5 (2002) 1057-1069
    • (2002) Mol. Cell , vol.10 , Issue.5 , pp. 1057-1069
    • Rolli, V.1    Gallwitz, M.2    Wossning, T.3    Flemming, A.4    Schamel, W.W.5    Zurn, C.6    Reth, M.7
  • 27
    • 0029655710 scopus 로고    scopus 로고
    • The promoter activity of long terminal repeats of the HERV-H family of human retrovirus-like elements is critically dependent on Sp1 family proteins interacting with a GC/GT box located immediately 3′ to the TATA box
    • Sjottem E., Anderssen S., and Johansen T. The promoter activity of long terminal repeats of the HERV-H family of human retrovirus-like elements is critically dependent on Sp1 family proteins interacting with a GC/GT box located immediately 3′ to the TATA box. J. Virol. 70 1 (1996) 188-198
    • (1996) J. Virol. , vol.70 , Issue.1 , pp. 188-198
    • Sjottem, E.1    Anderssen, S.2    Johansen, T.3
  • 28
    • 0034748390 scopus 로고    scopus 로고
    • Interferon-alpha-induced endogenous superantigen. a model linking environment and autoimmunity
    • Stauffer Y., Marguerat S., Meylan F., Ucla C., Sutkowski N., Huber B., Pelet T., and Conrad B. Interferon-alpha-induced endogenous superantigen. a model linking environment and autoimmunity. Immunity 15 4 (2001) 591-601
    • (2001) Immunity , vol.15 , Issue.4 , pp. 591-601
    • Stauffer, Y.1    Marguerat, S.2    Meylan, F.3    Ucla, C.4    Sutkowski, N.5    Huber, B.6    Pelet, T.7    Conrad, B.8
  • 29
    • 0034750690 scopus 로고    scopus 로고
    • Epstein-Barr virus transactivates the human endogenous retrovirus HERV-K18 that encodes a superantigen
    • Sutkowski N., Conrad B., Thorley-Lawson D.A., and Huber B.T. Epstein-Barr virus transactivates the human endogenous retrovirus HERV-K18 that encodes a superantigen. Immunity 15 4 (2001) 579-589
    • (2001) Immunity , vol.15 , Issue.4 , pp. 579-589
    • Sutkowski, N.1    Conrad, B.2    Thorley-Lawson, D.A.3    Huber, B.T.4
  • 30
    • 3142767678 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein LMP-2A is sufficient for transactivation of the HERV-K18 superantigen
    • Sutkowski N., Chen G., Calderon G., and Huber B.T. Epstein-Barr virus latent membrane protein LMP-2A is sufficient for transactivation of the HERV-K18 superantigen. J. Virol. 78 (2004) 7852-7860
    • (2004) J. Virol. , vol.78 , pp. 7852-7860
    • Sutkowski, N.1    Chen, G.2    Calderon, G.3    Huber, B.T.4
  • 31
    • 0033604292 scopus 로고    scopus 로고
    • Tyrosines 60, 64, and 101 of Epstein-Barr virus LMP2A are not essential for blocking B cell signal transduction
    • Swart R., Fruehling S., and Longnecker R. Tyrosines 60, 64, and 101 of Epstein-Barr virus LMP2A are not essential for blocking B cell signal transduction. Virology 263 2 (1999) 485-495
    • (1999) Virology , vol.263 , Issue.2 , pp. 485-495
    • Swart, R.1    Fruehling, S.2    Longnecker, R.3
  • 32
    • 0242374713 scopus 로고    scopus 로고
    • Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K
    • Tonjes R.R., Czauderna F., and Kurth R. Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K. J. Virol. 73 11 (1999) 9187-9195
    • (1999) J. Virol. , vol.73 , Issue.11 , pp. 9187-9195
    • Tonjes, R.R.1    Czauderna, F.2    Kurth, R.3
  • 33
    • 0035797901 scopus 로고    scopus 로고
    • Insertional polymorphisms of full-length endogenous retroviruses in humans
    • Turner G., Barbulescu M., Su M., Jensen-Seaman M.I., Kidd K.K., and Lenz J. Insertional polymorphisms of full-length endogenous retroviruses in humans. Curr. Biol. 11 19 (2001) 1531-1535
    • (2001) Curr. Biol. , vol.11 , Issue.19 , pp. 1531-1535
    • Turner, G.1    Barbulescu, M.2    Su, M.3    Jensen-Seaman, M.I.4    Kidd, K.K.5    Lenz, J.6
  • 34
    • 0035841664 scopus 로고    scopus 로고
    • Solitary human endogenous retroviruses-K LTRs retain transcriptional activity in vivo, the mode of which is different in different cell types
    • Vinogradova T.V., Leppik L.P., Nikolaev L.G., Akopov S.B., Kleiman A.M., Senyuta N.B., and Sverdlov E.D. Solitary human endogenous retroviruses-K LTRs retain transcriptional activity in vivo, the mode of which is different in different cell types. Virology 290 1 (2001) 83-90
    • (2001) Virology , vol.290 , Issue.1 , pp. 83-90
    • Vinogradova, T.V.1    Leppik, L.P.2    Nikolaev, L.G.3    Akopov, S.B.4    Kleiman, A.M.5    Senyuta, N.B.6    Sverdlov, E.D.7
  • 35
    • 0042346187 scopus 로고    scopus 로고
    • B cell receptor-mediated Syk-independent activation of phosphatidylinositol 3-kinase, Ras, and mitogen-activated protein kinase pathways
    • Yokozeki T., Adler K., Lankar D., and Bonnerot C. B cell receptor-mediated Syk-independent activation of phosphatidylinositol 3-kinase, Ras, and mitogen-activated protein kinase pathways. J. Immunol. 171 3 (2003) 1328-1335
    • (2003) J. Immunol. , vol.171 , Issue.3 , pp. 1328-1335
    • Yokozeki, T.1    Adler, K.2    Lankar, D.3    Bonnerot, C.4


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