HLA-DR, IL-4RA, and IL-10: Genetic risk factors in allergic bronchopulmonary aspergillosis

Pediatric Asthma, Allergy and Immunology

Volumn 21, Issue 4, 2008, Pages 185-190

  Knutsen, Alan P ^a,b   Kariuki, Barbara ^a,b   Santiago, Luis A ^a   Slavin, Raymond G ^a,b   Wofford, Jonathan D ^a   Bellone, Clifford ^a   Shah, Maulik R ^b  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SAINT LOUIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HLA DR ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4 RECEPTOR ALPHA;

ADULT; ARTICLE; ASTHMA; BRONCHOPULMONARY ASPERGILLOMA; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CYSTIC FIBROSIS; FEMALE; GENE FREQUENCY; GENETIC RISK; GENOTYPE; HUMAN; MALE; PRIORITY JOURNAL; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 60249097759     PISSN: 08831874     EISSN: None     Source Type: Journal    
DOI: 10.1089/pai.2008.0505     Document Type: Article

References (20)

1. Greenberger PA. Allergic bronchopulmonary aspergillosis. In: Adkinson NF Jr., Yunginer JW, Busse WW, Bochner BS, Holgate ST, Simons FER, eds. Allergy: principles and practice. St. Louis: Mosby, 2003, pp. 1353-1371.
2. Stevens DA, Moss R, Kurup VP, Knutsen AP, Greenberger P, Judson MA, Denning DW, Crameri R, Body A, Light M, Skov M, Maish W, Mastella G, and the Cystic Fibrosis Foundation Consensus Conference. Allergic bronchopulmonary aspergillosis in cystic fibrosis: Cystic Fibrosis Foundation Consensus Conference. Clin Infect Dis 37:S225-S264, 2003.
3. Chauhan B, Santiago L, Hutcheson PS, Schwartz H-J, Spitznagel E, Castro M, Slavin RG, Bellone CJ. Evidence for the involvement of two different MHC class II regions in susceptibility or protection in allergic bronchopulmonary aspergillosis. J Allergy Clin Immunol 2000; 106:723-729.
4. Chauhan B, Santiago L, Kirschmann DA, Hauptfield V, Knutsen AP, Hutcheson PS, Woulfe SL, Slavin RG, Schwartz HJ, Bellone CJ. The association of HLA-DR alleles and T-cell activation with allergic bronchopulmonary aspergillosis. J Immunol 1997; 159:4072-4076.
5. Chauhan BA, Knutsen AP, Hutcheson PS, Slavin RG, Bellone CJ. T cell subsets, epitope mapping, and HLA-restriction in patients with allergic bronchopulmonary aspergillosis. J Clin Invest 1996; 97:2324-2331.
6. Khan SP, McClellan JS, Knutsen AP. Increased sensitivity to IL-4 in patients with allergic bronchopulmonary aspergillosis and atopy. Inter Arch Allergy Immunol 2000; 123:319-326.
7. Knutsen AP, Hutcheson PS, Albers GM, Consolino J, Smick J, Kurup VP. Increased sensitivity to IL-4 in cystic fibrosis patients with allergic bronchopulmonary aspergillosis. Allergy 2003; 58:81-87.
8. Knutsen AP, Kariuki B, Consolino JD, Warrier MR. IL-4 alpha chain receptor (IL-4RA) polymorphisms in allergic bronchopulmonary aspergillosis. Clin Mol Allergy 2006; 3:1-6.
9. Liu X, Beaty TH, Deindl P, Huang S-K, Lau S, Sommerfeld C, Fallin MD, Kao WHL, Wahn U, Nickel R. Associations between total serum IgE levels and the 6 potentially functional variants with the genes IL-4, IL-13, and IL-4RA in German children: the German Multicenter Atopy Study. J Allergy Clin Immunol 2003; 112:382-388.
10. Ober C, Leavitt SA, Tsalenko A, Howard TD, Hoki DM, Daniel R, Newman DL, Wu X, Parry R, Lester LA, Solway J, Blumenthal M, King RA, Xu J, Meyers DA, Bleecker ER, Cox NJ. Variation in the interleukin 4-receptor a gene confers susceptibility to asthma and atopy in ethnically diverse populations. Am J Hum Genet 2000; 66:517-526.
11. Hershey GKK, Friedrich MF, Esswein LA, Thomas ML, Chatila TA. The association of atopy with a gain-of-function mutation in the α subunit of the interleukin-4 receptor. N Engl J Med 1997; 337:1720-1725.
12. Chen W, Ericksen MB, Hershey GKK, Functional effect of the R110Q IL13 genetic variant alone and in combination with IL4RA genetic variants. J Allergy Clin Immuno 2004; 114:553-560.
13. Vladich FD, Brazille SM, Stern D, Peck ML, Ghittoni R, Vercelli D. IL-13 R130Q, a common variant associated with allergy and asthma, enhances effector mechanisms essential for human allergic inflammation. J Clin Invest 2005; 115:747-754.
14. Brouard J, Knauer N, Boelle P-Y, Corvol H, Henrion-Caude A, Flamant C, Bremont F, Delaisi B, Duhamel J-F, Marguet C, Roussey M, Miesch M-C, Chadelat K, Boule M, Fauroux B, Ratjen F, Grasemann H, Clement A. Influence of interleukin-10 on airways colonization by Aspergillus fumigatus in cystic fibrosis patients. J Infect Dis 2005; 191:1988-1991.
15. Guzowski D, Chandrasekaran A, Gawel C, Palma J, Koenig J, Wang XP, Dosik M, Kaplan M, Chu CC, Chavan S, Furie R, Albesiano E, Chiorazzi N, Goodwin L. Analysis of single nucleotide polymorphisms in the promoter region of interleukin-10 by denaturing high-performance liquid chromatography. J Biomol Tech 2005; 16:154-166.
16. Graves PE, Kabesch M, Halonen M, Holberg CJ, Baldini M, Fritzsch C, Weiland SK, Erickson RP, von Mutius E, Martinez FD. A cluster of seven tightly linked polymorphisms in the IL-13 gene is associated with total serum IgE levels in three populations of white children. J Allergy Clin Immunol 2000; 105:506-513.
17. Cohen, J. Statistical power analysis for the behavioral sciences, 2nd edn. New Jersey: Lawrence Erlbaum Associates, 1998.
18. Bland, JM and Altman DG. 1995. Multiple significance tests: the Bonferroni method. BMJ 310:170.
19. De Waal Malefyt R, Figdor CG, de Vries JE. Regulation of human monocyte functions by Interleukin-10. In de Vries JE, de Waal-Malefyt R eds. Interleukin-10. Heidelberg: Springer-Verlag, 1995, pp. 37-52.
20. Saxena S, Madan T, Shah A, Muralidhar K, Sarma PU. Association of polymorphisms in the collagen region of SP-A2 with increased levels of total IgE antibodies and eosinophilia in patients with allergic bronchopulmonary aspergillosis. J Allergy Clin Immunol 2003; 111:1001-1007.