IL-4 alpha chain receptor (IL-4Rα) polymorphisms in allergic bronchopulmonary sspergillosis

Clinical and Molecular Allergy

Volumn 4, Issue , 2006, Pages

  Knutsen, Alan P ^a,b   Kariuki, Barbara ^a   Consolino, Judy D ^a   Warrier, Manoj R ^a  

^a SAINT LOUIS UNIVERSITY   (United States)

^b Pediatric Research Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HLA DR ANTIGEN; INTERLEUKIN 4 RECEPTOR ALPHA; ISOLEUCINE; VALINE;

ADULT; ANTIGEN EXPRESSION; ARTICLE; ASTHMA; B LYMPHOCYTE; CONTROLLED STUDY; CYSTIC FIBROSIS; FEMALE; FLOW CYTOMETRY; GENETIC RISK; GENOTYPE; HUMAN; HUMAN CELL; LUNG ASPERGILLOSIS; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; RISK FACTOR; SENSITIVITY ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL ANALYSIS; UPREGULATION;

EID: 33645033038     PISSN: 14767961     EISSN: 14767961     Source Type: Journal    
DOI: 10.1186/1476-7961-4-3     Document Type: Article

References (30)

1. Greenberger PA: Allergic bronchopulmonary aspergillosis. In Allergy: Principles and Practice Edited by: Adkinson NF Jr, Yunginer JW, Busse WW, Bochner BS, Holgate ST, Simons FER. Mosby, St. Louis; 2003:1353-1371.
2. Stevens DA, Moss R, Kurup VP, Knutsen AP, Greenberger P, Judson MA, Denning DW, Crameri R, Brody A, Light M, Skov M, Maish W, Mastella G, the Cystic Fibrosis Foundation Consensus Conference: Allergic bronchopulmonary aspergillosis in cystic fibrosis: Cystic Fibrosis Foundation Consensus Conference. Clin Infect Dis 2003, 37:S225-S264.
3. Chauhan B, Santiago L, Hutcheson PS, Schwartz HJ, Spitznagel E, Castro M, Slavin RG, Bellone CJ: Evidence for the involvement of two different MHC class II regions in susceptibility or protection in allergic bronchopulmonary aspergillosis. J Allergy Clin Immunol 2000, 106:723-729.
4. Chauhan B, Santiago L, Kirschmann DA, Hauptfeld V, Knutsen AP, Hutcheson PS, Woulfe SL, Slavin RG, Schwartz HJ, Bellone CJ: The association of HLA-DR alleles and T cell activation with allergic bronchopulmonary aspergillosis. J Immunol 1997, 159:4072-4076.
5. Chauhan BA, Knutsen AP, Hutcheson PS, Slavin RG, Bellone CJ: T cell subsets, epitope mapping, and HLA-restriction in patients with allergic bronchopulmonary aspergillosis. J Clin Invest 1996, 97:2324-2331.
6. Khan SP, McClellan JS, Knutsen AP: Increased sensitivity to IL-4 in patients with allergic bronchopulmonary aspergillosis and atopy. Inter Arch Allergy Immunol 2000, 123:319-326.
7. Knutsen AP, Hutcheson PS, Albers GM, Consolino J, Smick J, Kurup VP: Increased sensitivity to IL-4 in cystic fibrosis patients with allergic bronchopulmonary aspergillosis. Allergy 2004, 58:81-88.
8. Hershey GKK, Friedrich MF, Esswein LA, Thomas ML, Chatila TA: Association of atopy with a gain-of-function mutation in the interleukin-4 receptor a chain. N Engl J Med 1997, 337:1720-1725.
9. Mitsuyasu H, Izuhara K, Mao XQ, Gao PS, Arinobu Y, Enomoto T, Kawai M, Sasaki S, Dake Y, Hamasaki N, Shirakawa T, Hopkin JM: Ile50Val variant of IL4R alpha upregulates IgE synthesis and associates with atopic asthma. Nat Genet 1998, 19:119-120.
10. Deichmann K, Bardutsky J, Forster J, Heinzmann A, Kuehr J: Common polymorphisms in the coding part of the IL-4 receptor gene. Biochim Biophys Acta 1997, 231:696-697.
11. Kruse S, Japha T, Tedner M, Sparholt SH, Forster J, Kuehr J, Deichmann KA: The polymorphisms S503P and Q576R in the interleukin-4 receptor alpha gene are associated with atopy and influence the signal transduction. Immunology 1999, 96:265-271.
12. Ober C, Leavitt SA, Tsalenko A, Howard TD, Hoki DM, Daniel R, Newman DL, Wu X, Parry R, Lester LA, Solway J, Blumenthal M, King RA, Xu J, Meyers DA, Bleecker ER, Cox NJ: Variation in the interleukin-4 receptor alpha gene confers susceptibility to asthma and atopy in ethnically diverse populations. Am J Hum Genet 2000, 66:517-526.
13. Wjst M, Kruse S, Illig T, Deichmann K: Asthma and IL-4 receptor alpha gene variants. Eur J Immunogenetics 2002, 29:263-268.
14. Rosa-Rosa L, Zimmermann N, Bernstein JA, Rothenberg ME, Khurana Hershey GK: The R576 IL-4 receptor alpha allele correlates with asthma severity. J Allergy Clin Immunol 1999, 104:1008-1014.
15. Mitsuyasu H, Yanagihara Y, Mao X, Gao P, Arinobu Y, Ihara K, Takabayashi A, Hana T, Enomoto T, Sasaki S, Kawai M, Hamasaki N, Shirakawa T, Hopkin JM, Izuhara K: Cutting edge: Dominant effect of Ile50Val variant of the human IL-4 receptor α-chain in IgE synthesis. J Immunol 1999, 162:1227-1231.
16. Risma KA, Wang N, Andrews RP, Cunningham CM, Ericksen MB, Bernstein JA, Chakraborty R, Hershey GK: V75R576 IL-4 receptor alpha is associated with allergic asthma and enhanced IL-4 receptor function. J Immunol 2002, 169:1604-1610.
17. Hackstein H, Kluter H, Fricke L, Hoyer J, Bein G: The IL-4 receptor alpha-chain variant Q576R is strongly associated with decreased kidney allograft survival. Tissue Antigens 1999, 54:471-477.
18. Bux J, Stein EL, Berling P, Fromont P, Clay M, Stroncel D, Santoso S: Characterization of a new alloantigen (SH) on the human neutrophil Fc gamma receptor Illb. Blood 1997, 89:1027-1034.
19. Knutsen AP, Warrier MR, Noyes B, Consolino J: Allergic bronchopulmonary aspergillosis in a patient with cystic fibrosis: diagnostic criteria when the IgE level is <500 IU/ml. Ann Allergy Asthma Immunol 2005 in press.
20. Verhoef A, Higgins JA, Thorpe CJ, Marsh SG, Hayball JD, Lamb JR, O'Hehir RE: Clonal analysis of the atopic immune response to the group 2 allergen of Dermatophagoides spp.: identification of HLA-DR and -DQ restricted T cell epitopes. Inter Immunol 1993, 5:1589-1597.
21. Lamb JR, Higgins JA, Hetzel C, Hayball JD, Lake RA, O'Hehir RE: The effects of changes at peptide residues contacting MHC class II T-cell receptor on antigen recognition and human Th0 cell effector function. Immunol 1995, 85:447-454.
22. + T cells. J Immunol 1996, 157:2160-2165.
23. Pfeiffer C, Stein J, Southwood S, Ketelaar H, Sette A, Bottomly K: Altered peptide ligands can control CD4 T lymphocyte differentiation in vivo. J Exp Med 1995, 181:1569-1574.
24. Evavold BD, Sloan-Lancaster J, Hsu BL, Allen PM: Separation of T helper I clone cytolysis from proliferation and lymphokine production using analog peptides. J Immunol 1993, 150:3131-3140.
25. Racioppi L, Ronchese F, Matis LA, Germain RN: Peptide-major histocompatibility complex class II complexes with agonist/antagonist properties provide evidence for ligand related differences in T cell receptor dependent intracellular signaling. J Exp Med 1993, 177:1047-1060.
26. Chen W, Ericksen MB, Hershey GKK: Functional effect of the R110Q IL13 genetic variant alone and in combination with IL4RA genetic variants. J Allergy Clin Immuno 2004, 114-553-560.
27. Vladich FD, Brazille SM, Stern D, Peck ML, Ghittoni R, Vercelli D: IL13 R130Q, a common variant associated with allergy and asthma, enhances effector mechanisms essential for human allergic inflammation. J Clin Invest 2005, 115:747-754.
28. Saxena S, Madan T, Shah A, Muralidhar K, Sarma PA: Association of polymorphisms in the collagen region of SP-A2 with increased levels of total IgE antibodies and eosinophilia in patients with allergic bronchopulmonary aspergillosis. J Allergy Clin Immunol 2003, 111:1001-1007.
29. Karjalainen J, Hulkkonen J, Nieminen MM, Huhtala H, Aromaa A, Klaukka T, Hurme M: Interieukin- 10 gene promoter region polymorphism is associated with eosinophil count and circulating immunoglobulin E in adult asthma. Clin Exp Allergy 2003, 33:78-83.
30. Brouard J, Knauer N, Boelle P-Y, Corvol H, Henrion-Caude A, Flamant C, Bremont F, Delaisi B, Duhamel J-F, Marguet C, Roussey M, Miesch M-C, Chadelat K, Boule M, Fauroux B, Ratjen F, Grasemann H, Clement A. Influence of interleukin- 10 on airways colonization by Aspergillus fumigatus in cystic fibrosis patients. J Infect Dis 2005, 191:1988-1991.