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Volumn 33, Issue 4, 2009, Pages 539-546

Acute myeloid leukemic cell lines loaded with synthetic dsRNA trigger IFN-γ secretion by human NK cells

Author keywords

Acute myeloid leukemia; dsRNA; Electroporation; Human NK cells; IFN ; Poly(I:C)

Indexed keywords

ALPHA INTERFERON; DOUBLE STRANDED RNA; GAMMA INTERFERON;

EID: 60249095792     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2008.08.020     Document Type: Article
Times cited : (12)

References (60)
  • 1
    • 33745601681 scopus 로고    scopus 로고
    • Tumor growth impedes natural-killer-cell maturation in the bone marrow
    • Richards J.O., Chang X., Blaser B.W., Caligiuri M.A., Zheng P., and Liu Y. Tumor growth impedes natural-killer-cell maturation in the bone marrow. Blood 108 (2006) 246-252
    • (2006) Blood , vol.108 , pp. 246-252
    • Richards, J.O.1    Chang, X.2    Blaser, B.W.3    Caligiuri, M.A.4    Zheng, P.5    Liu, Y.6
  • 3
    • 21344457276 scopus 로고    scopus 로고
    • The role of natural killer cells in tumor control--effectors and regulators of adaptive immunity
    • Wallace M.E., and Smyth M.J. The role of natural killer cells in tumor control--effectors and regulators of adaptive immunity. Springer Semin Immunopathol 27 (2005) 49-64
    • (2005) Springer Semin Immunopathol , vol.27 , pp. 49-64
    • Wallace, M.E.1    Smyth, M.J.2
  • 4
    • 33845987986 scopus 로고    scopus 로고
    • Deficient expression of NCR in NK cells from acute myeloid leukemia: evolution during leukemia treatment and impact of leukemia cells in NCRdull phenotype induction
    • Fauriat C., Just-Landi S., Mallet F., Arnoulet C., Sainty D., Olive D., et al. Deficient expression of NCR in NK cells from acute myeloid leukemia: evolution during leukemia treatment and impact of leukemia cells in NCRdull phenotype induction. Blood 109 (2007) 323-330
    • (2007) Blood , vol.109 , pp. 323-330
    • Fauriat, C.1    Just-Landi, S.2    Mallet, F.3    Arnoulet, C.4    Sainty, D.5    Olive, D.6
  • 5
    • 0029887832 scopus 로고    scopus 로고
    • Natural killer cell activity and cytokine production as prognostic factors in adult acute leukemia
    • Tajima F., Kawatani T., Endo A., and Kawasaki H. Natural killer cell activity and cytokine production as prognostic factors in adult acute leukemia. Leukemia 10 (1996) 478-482
    • (1996) Leukemia , vol.10 , pp. 478-482
    • Tajima, F.1    Kawatani, T.2    Endo, A.3    Kawasaki, H.4
  • 6
    • 0037093066 scopus 로고    scopus 로고
    • Defective expression and function of natural killer cell-triggering receptors in patients with acute myeloid leukemia
    • Costello R.T., Sivori S., Marcenaro E., Lafage-Pochitaloff M., Mozziconacci M.J., Reviron D., et al. Defective expression and function of natural killer cell-triggering receptors in patients with acute myeloid leukemia. Blood 99 (2002) 3661-3667
    • (2002) Blood , vol.99 , pp. 3661-3667
    • Costello, R.T.1    Sivori, S.2    Marcenaro, E.3    Lafage-Pochitaloff, M.4    Mozziconacci, M.J.5    Reviron, D.6
  • 7
    • 24744444973 scopus 로고    scopus 로고
    • Defective killing of dendritic cells by autologous natural killer cells from acute myeloid leukemia patients
    • Fauriat C., Moretta A., Olive D., and Costello R.T. Defective killing of dendritic cells by autologous natural killer cells from acute myeloid leukemia patients. Blood 106 (2005) 2186-2188
    • (2005) Blood , vol.106 , pp. 2186-2188
    • Fauriat, C.1    Moretta, A.2    Olive, D.3    Costello, R.T.4
  • 8
    • 33750530369 scopus 로고    scopus 로고
    • Acute myeloid leukemia: epidemiology and etiology
    • Deschler B., and Lubbert M. Acute myeloid leukemia: epidemiology and etiology. Cancer 107 (2006) 2099-2107
    • (2006) Cancer , vol.107 , pp. 2099-2107
    • Deschler, B.1    Lubbert, M.2
  • 9
    • 0036379698 scopus 로고    scopus 로고
    • Immunological weapons against acute myeloid leukaemia
    • Galea-Lauri J. Immunological weapons against acute myeloid leukaemia. Immunology 107 (2002) 20-27
    • (2002) Immunology , vol.107 , pp. 20-27
    • Galea-Lauri, J.1
  • 11
    • 42449123606 scopus 로고    scopus 로고
    • Natural killer cell-directed therapies: moving from unexpected results to successful strategies
    • Terme M., Ullrich E., Delahaye N.F., Chaput N., and Zitvogel L. Natural killer cell-directed therapies: moving from unexpected results to successful strategies. Nat Immunol 9 (2008) 486-494
    • (2008) Nat Immunol , vol.9 , pp. 486-494
    • Terme, M.1    Ullrich, E.2    Delahaye, N.F.3    Chaput, N.4    Zitvogel, L.5
  • 12
    • 0036716947 scopus 로고    scopus 로고
    • NK cells: a lesson from mismatched hematopoietic transplantation
    • Velardi A., Ruggeri L., Alessandro, Moretta, and Moretta L. NK cells: a lesson from mismatched hematopoietic transplantation. Trends Immunol 23 (2002) 438-444
    • (2002) Trends Immunol , vol.23 , pp. 438-444
    • Velardi, A.1    Ruggeri, L.2    Alessandro3    Moretta4    Moretta, L.5
  • 13
    • 0346656670 scopus 로고    scopus 로고
    • Immunobiology of haematological malignant disorders: the basis for novel immunotherapy protocols
    • Costello R.T., Fauriat C., Rey J., Gastaut J.A., and Olive D. Immunobiology of haematological malignant disorders: the basis for novel immunotherapy protocols. Lancet Oncol 5 (2004) 47-55
    • (2004) Lancet Oncol , vol.5 , pp. 47-55
    • Costello, R.T.1    Fauriat, C.2    Rey, J.3    Gastaut, J.A.4    Olive, D.5
  • 16
    • 35748976563 scopus 로고    scopus 로고
    • Engagement of TLR3, TLR7, and NKG2D regulate IFN-gamma secretion but not NKG2D-mediated cytotoxicity by human NK cells stimulated with suboptimal doses of IL-12
    • Girart M.V., Fuertes M.B., Domaica C.I., Rossi L.E., and Zwirner N.W. Engagement of TLR3, TLR7, and NKG2D regulate IFN-gamma secretion but not NKG2D-mediated cytotoxicity by human NK cells stimulated with suboptimal doses of IL-12. J Immunol 179 (2007) 3472-3479
    • (2007) J Immunol , vol.179 , pp. 3472-3479
    • Girart, M.V.1    Fuertes, M.B.2    Domaica, C.I.3    Rossi, L.E.4    Zwirner, N.W.5
  • 17
    • 0036005884 scopus 로고    scopus 로고
    • The roles of IFN gamma in protection against tumor development and cancer immunoediting
    • Ikeda H., Old L.J., and Schreiber R.D. The roles of IFN gamma in protection against tumor development and cancer immunoediting. Cytokine Growth Factor Rev 13 (2002) 95-109
    • (2002) Cytokine Growth Factor Rev , vol.13 , pp. 95-109
    • Ikeda, H.1    Old, L.J.2    Schreiber, R.D.3
  • 18
    • 33750321707 scopus 로고    scopus 로고
    • Interferons, immunity and cancer immunoediting
    • Dunn G.P., Koebel C.M., and Schreiber R.D. Interferons, immunity and cancer immunoediting. Nat Rev Immunol 6 (2006) 836-848
    • (2006) Nat Rev Immunol , vol.6 , pp. 836-848
    • Dunn, G.P.1    Koebel, C.M.2    Schreiber, R.D.3
  • 19
    • 33750470437 scopus 로고    scopus 로고
    • The direct effects of Toll-like receptor ligands on human NK cell cytokine production and cytotoxicity
    • Lauzon N.M., Mian F., MacKenzie R., and Ashkar A.A. The direct effects of Toll-like receptor ligands on human NK cell cytokine production and cytotoxicity. Cell Immunol 241 (2006) 102-112
    • (2006) Cell Immunol , vol.241 , pp. 102-112
    • Lauzon, N.M.1    Mian, F.2    MacKenzie, R.3    Ashkar, A.A.4
  • 22
    • 0034193991 scopus 로고    scopus 로고
    • Development of Th1-inducing capacity in myeloid dendritic cells requires environmental instruction
    • Vieira P.L., de Jong E.C., Wierenga E.A., Kapsenberg M.L., and Kalinski P. Development of Th1-inducing capacity in myeloid dendritic cells requires environmental instruction. J Immunol 164 (2000) 4507-4512
    • (2000) J Immunol , vol.164 , pp. 4507-4512
    • Vieira, P.L.1    de Jong, E.C.2    Wierenga, E.A.3    Kapsenberg, M.L.4    Kalinski, P.5
  • 23
    • 33947207453 scopus 로고    scopus 로고
    • Cytokine-driven regulation of NK cell functions in tumor immunity: role of the MICA-NKG2D system
    • Zwirner N.W., Fuertes M.B., Girart M.V., Domaica C.I., and Rossi L.E. Cytokine-driven regulation of NK cell functions in tumor immunity: role of the MICA-NKG2D system. Cytokine Growth Factor Rev 18 (2007) 159-170
    • (2007) Cytokine Growth Factor Rev , vol.18 , pp. 159-170
    • Zwirner, N.W.1    Fuertes, M.B.2    Girart, M.V.3    Domaica, C.I.4    Rossi, L.E.5
  • 24
    • 38649105188 scopus 로고    scopus 로고
    • Enhanced antitumor immunity elicited by dendritic cell vaccines is a result of their ability to engage both CTL and IFNgamma-producing NK cells
    • Karimi K., Boudreau J.E., Fraser K., Liu H., Delanghe J., Gauldie J., et al. Enhanced antitumor immunity elicited by dendritic cell vaccines is a result of their ability to engage both CTL and IFNgamma-producing NK cells. Mol Ther 16 (2008) 411-418
    • (2008) Mol Ther , vol.16 , pp. 411-418
    • Karimi, K.1    Boudreau, J.E.2    Fraser, K.3    Liu, H.4    Delanghe, J.5    Gauldie, J.6
  • 25
    • 0032903599 scopus 로고    scopus 로고
    • Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo
    • Fernandez N.C., Lozier A., Flament C., Ricciardi-Castagnoli P., Bellet D., Suter M., et al. Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo. Nat Med 5 (1999) 405-411
    • (1999) Nat Med , vol.5 , pp. 405-411
    • Fernandez, N.C.1    Lozier, A.2    Flament, C.3    Ricciardi-Castagnoli, P.4    Bellet, D.5    Suter, M.6
  • 26
    • 11144357190 scopus 로고    scopus 로고
    • Role of cross-talk between IFN-alpha-induced monocyte-derived dendritic cells and NK cells in priming CD8+ T cell responses against human tumor antigens
    • Tosi D., Valenti R., Cova A., Sovena G., Huber V., Pilla L., et al. Role of cross-talk between IFN-alpha-induced monocyte-derived dendritic cells and NK cells in priming CD8+ T cell responses against human tumor antigens. J Immunol 172 (2004) 5363-5370
    • (2004) J Immunol , vol.172 , pp. 5363-5370
    • Tosi, D.1    Valenti, R.2    Cova, A.3    Sovena, G.4    Huber, V.5    Pilla, L.6
  • 28
    • 33750682077 scopus 로고    scopus 로고
    • Multidirectional interactions are bridging human NK cells with plasmacytoid and monocyte-derived dendritic cells during innate immune responses
    • Della C.M., Romagnani C., Thiel A., Moretta L., and Moretta A. Multidirectional interactions are bridging human NK cells with plasmacytoid and monocyte-derived dendritic cells during innate immune responses. Blood 108 (2006) 3851-3858
    • (2006) Blood , vol.108 , pp. 3851-3858
    • Della, C.M.1    Romagnani, C.2    Thiel, A.3    Moretta, L.4    Moretta, A.5
  • 29
    • 1642444661 scopus 로고    scopus 로고
    • NK cell compartments and their activation by dendritic cells
    • Ferlazzo G., and Munz C. NK cell compartments and their activation by dendritic cells. J Immunol 172 (2004) 1333-1339
    • (2004) J Immunol , vol.172 , pp. 1333-1339
    • Ferlazzo, G.1    Munz, C.2
  • 30
    • 10644249213 scopus 로고    scopus 로고
    • Helper role of NK cells during the induction of anticancer responses by dendritic cells
    • Kalinski P., Giermasz A., Nakamura Y., Basse P., Storkus W.J., Kirkwood J.M., et al. Helper role of NK cells during the induction of anticancer responses by dendritic cells. Mol Immunol 42 (2005) 535-539
    • (2005) Mol Immunol , vol.42 , pp. 535-539
    • Kalinski, P.1    Giermasz, A.2    Nakamura, Y.3    Basse, P.4    Storkus, W.J.5    Kirkwood, J.M.6
  • 31
    • 33750689486 scopus 로고    scopus 로고
    • Effector and regulatory events during natural killer-dendritic cell interactions
    • Moretta L., Ferlazzo G., Bottino C., Vitale M., Pende D., Mingari M.C., et al. Effector and regulatory events during natural killer-dendritic cell interactions. Immunol Rev 214 (2006) 219-228
    • (2006) Immunol Rev , vol.214 , pp. 219-228
    • Moretta, L.1    Ferlazzo, G.2    Bottino, C.3    Vitale, M.4    Pende, D.5    Mingari, M.C.6
  • 32
  • 33
    • 30144443832 scopus 로고    scopus 로고
    • Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion
    • Bryceson Y.T., March M.E., Ljunggren H.G., and Long E.O. Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion. Blood 107 (2006) 159-166
    • (2006) Blood , vol.107 , pp. 159-166
    • Bryceson, Y.T.1    March, M.E.2    Ljunggren, H.G.3    Long, E.O.4
  • 34
    • 0042931206 scopus 로고    scopus 로고
    • Dendritic cells mediate NK cell help for Th1 and CTL responses: two-signal requirement for the induction of NK cell helper function
    • Mailliard R.B., Son Y.I., Redlinger R., Coates P.T., Giermasz A., Morel P.A., et al. Dendritic cells mediate NK cell help for Th1 and CTL responses: two-signal requirement for the induction of NK cell helper function. J Immunol 171 (2003) 2366-2373
    • (2003) J Immunol , vol.171 , pp. 2366-2373
    • Mailliard, R.B.1    Son, Y.I.2    Redlinger, R.3    Coates, P.T.4    Giermasz, A.5    Morel, P.A.6
  • 35
    • 0036668242 scopus 로고    scopus 로고
    • Links between innate and adaptive immunity via type I interferon
    • Le Bon A., and Tough D.F. Links between innate and adaptive immunity via type I interferon. Curr Opin Immunol 14 (2002) 432-436
    • (2002) Curr Opin Immunol , vol.14 , pp. 432-436
    • Le Bon, A.1    Tough, D.F.2
  • 37
    • 37849188401 scopus 로고    scopus 로고
    • Multi-directional cross-regulation of NK cell function during innate immune responses
    • Marcenaro E., Dondero A., and Moretta A. Multi-directional cross-regulation of NK cell function during innate immune responses. Transpl Immunol 17 (2006) 16-19
    • (2006) Transpl Immunol , vol.17 , pp. 16-19
    • Marcenaro, E.1    Dondero, A.2    Moretta, A.3
  • 38
    • 34250203538 scopus 로고    scopus 로고
    • Type I IFN contributes to NK cell homeostasis, activation, and antitumor function
    • Swann J.B., Hayakawa Y., Zerafa N., Sheehan K.C., Scott B., Schreiber R.D., et al. Type I IFN contributes to NK cell homeostasis, activation, and antitumor function. J Immunol 178 (2007) 7540-7549
    • (2007) J Immunol , vol.178 , pp. 7540-7549
    • Swann, J.B.1    Hayakawa, Y.2    Zerafa, N.3    Sheehan, K.C.4    Scott, B.5    Schreiber, R.D.6
  • 39
    • 34447633748 scopus 로고    scopus 로고
    • Proinflammatory response of human leukemic cells to dsRNA transfection linked to activation of dendritic cells
    • Smits E.L., Ponsaerts P., Van de Velde A.L., Van Driessche A., Cools N., Lenjou M., et al. Proinflammatory response of human leukemic cells to dsRNA transfection linked to activation of dendritic cells. Leukemia 21 (2007) 1691-1699
    • (2007) Leukemia , vol.21 , pp. 1691-1699
    • Smits, E.L.1    Ponsaerts, P.2    Van de Velde, A.L.3    Van Driessche, A.4    Cools, N.5    Lenjou, M.6
  • 40
    • 0035412401 scopus 로고    scopus 로고
    • Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells
    • Van Tendeloo V.F., Ponsaerts P., Lardon F., Nijs G., Lenjou M., Van Broeckhoven C., et al. Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells. Blood 98 (2001) 49-56
    • (2001) Blood , vol.98 , pp. 49-56
    • Van Tendeloo, V.F.1    Ponsaerts, P.2    Lardon, F.3    Nijs, G.4    Lenjou, M.5    Van Broeckhoven, C.6
  • 41
    • 0033561762 scopus 로고    scopus 로고
    • Differential cytokine and chemokine gene expression by human NK cells following activation with IL-18 or IL-15 in combination with IL-12: implications for the innate immune response
    • Fehniger T.A., Shah M.H., Turner M.J., VanDeusen J.B., Whitman S.P., Cooper M.A., et al. Differential cytokine and chemokine gene expression by human NK cells following activation with IL-18 or IL-15 in combination with IL-12: implications for the innate immune response. J Immunol 162 (1999) 4511-4520
    • (1999) J Immunol , vol.162 , pp. 4511-4520
    • Fehniger, T.A.1    Shah, M.H.2    Turner, M.J.3    VanDeusen, J.B.4    Whitman, S.P.5    Cooper, M.A.6
  • 42
    • 0034939227 scopus 로고    scopus 로고
    • IFN-alpha and IL-18 synergistically enhance IFN-gamma production in human NK cells: differential regulation of Stat4 activation and IFN-gamma gene expression by IFN-alpha and IL-12
    • Matikainen S., Paananen A., Miettinen M., Kurimoto M., Timonen T., Julkunen I., et al. IFN-alpha and IL-18 synergistically enhance IFN-gamma production in human NK cells: differential regulation of Stat4 activation and IFN-gamma gene expression by IFN-alpha and IL-12. Eur J Immunol 31 (2001) 2236-2245
    • (2001) Eur J Immunol , vol.31 , pp. 2236-2245
    • Matikainen, S.1    Paananen, A.2    Miettinen, M.3    Kurimoto, M.4    Timonen, T.5    Julkunen, I.6
  • 44
  • 45
    • 13444311714 scopus 로고    scopus 로고
    • Close encounters of different kinds: dendritic cells and NK cells take centre stage
    • Degli-Esposti M.A., and Smyth M.J. Close encounters of different kinds: dendritic cells and NK cells take centre stage. Nat Rev Immunol 5 (2005) 112-124
    • (2005) Nat Rev Immunol , vol.5 , pp. 112-124
    • Degli-Esposti, M.A.1    Smyth, M.J.2
  • 46
    • 3042711969 scopus 로고    scopus 로고
    • CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: induction of cytokine release and cytotoxicity against tumors and dendritic cells
    • Sivori S., Falco M., Della C.M., Carlomagno S., Vitale M., Moretta L., et al. CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: induction of cytokine release and cytotoxicity against tumors and dendritic cells. Proc Natl Acad Sci USA 101 (2004) 10116-10121
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 10116-10121
    • Sivori, S.1    Falco, M.2    Della, C.M.3    Carlomagno, S.4    Vitale, M.5    Moretta, L.6
  • 47
    • 22544473593 scopus 로고    scopus 로고
    • TLR7/8-mediated activation of human NK cells results in accessory cell-dependent IFN-gamma production
    • Hart O.M., Athie-Morales V., O'Connor G.M., and Gardiner C.M. TLR7/8-mediated activation of human NK cells results in accessory cell-dependent IFN-gamma production. J Immunol 175 (2005) 1636-1642
    • (2005) J Immunol , vol.175 , pp. 1636-1642
    • Hart, O.M.1    Athie-Morales, V.2    O'Connor, G.M.3    Gardiner, C.M.4
  • 48
    • 10244270620 scopus 로고    scopus 로고
    • p38 MAPK activation controls the TLR3-mediated up-regulation of cytotoxicity and cytokine production in human NK cells
    • Pisegna S., Pirozzi G., Piccoli M., Frati L., Santoni A., and Palmieri G. p38 MAPK activation controls the TLR3-mediated up-regulation of cytotoxicity and cytokine production in human NK cells. Blood 104 (2004) 4157-4164
    • (2004) Blood , vol.104 , pp. 4157-4164
    • Pisegna, S.1    Pirozzi, G.2    Piccoli, M.3    Frati, L.4    Santoni, A.5    Palmieri, G.6
  • 49
    • 0346734195 scopus 로고    scopus 로고
    • APC-independent activation of NK cells by the Toll-like receptor 3 agonist double-stranded RNA
    • Schmidt K.N., Leung B., Kwong M., Zarember K.A., Satyal S., Navas T.A., et al. APC-independent activation of NK cells by the Toll-like receptor 3 agonist double-stranded RNA. J Immunol 172 (2004) 138-143
    • (2004) J Immunol , vol.172 , pp. 138-143
    • Schmidt, K.N.1    Leung, B.2    Kwong, M.3    Zarember, K.A.4    Satyal, S.5    Navas, T.A.6
  • 50
    • 40349084108 scopus 로고    scopus 로고
    • Tonsilar NK Cells Restrict B Cell Transformation by the Epstein-Barr Virus via IFN-gamma
    • Strowig T., Brilot F., Arrey F., Bougras G., Thomas D., Muller W.A., et al. Tonsilar NK Cells Restrict B Cell Transformation by the Epstein-Barr Virus via IFN-gamma. PLoS Pathog 4 (2008) e27
    • (2008) PLoS Pathog , vol.4
    • Strowig, T.1    Brilot, F.2    Arrey, F.3    Bougras, G.4    Thomas, D.5    Muller, W.A.6
  • 51
    • 11844268647 scopus 로고    scopus 로고
    • The reciprocal interaction of NK cells with plasmacytoid or myeloid dendritic cells profoundly affects innate resistance functions
    • Gerosa F., Gobbi A., Zorzi P., Burg S., Briere F., Carra G., et al. The reciprocal interaction of NK cells with plasmacytoid or myeloid dendritic cells profoundly affects innate resistance functions. J Immunol 174 (2005) 727-734
    • (2005) J Immunol , vol.174 , pp. 727-734
    • Gerosa, F.1    Gobbi, A.2    Zorzi, P.3    Burg, S.4    Briere, F.5    Carra, G.6
  • 52
    • 0032792876 scopus 로고    scopus 로고
    • Generation of autologous immunity to acute myeloid leukaemia and maintenance of complete remission following interferon-alpha treatment
    • Lowdell M.W., Craston R., and Prentice H.G. Generation of autologous immunity to acute myeloid leukaemia and maintenance of complete remission following interferon-alpha treatment. Cytokines Cell Mol Ther 5 (1999) 119-121
    • (1999) Cytokines Cell Mol Ther , vol.5 , pp. 119-121
    • Lowdell, M.W.1    Craston, R.2    Prentice, H.G.3
  • 53
    • 0033120418 scopus 로고    scopus 로고
    • A pilot study of interleukin-2 for adult patients with acute myelogenous leukemia in first complete remission
    • Cortes J.E., Kantarjian H.M., O'Brien S., Giles F., Keating M.J., Freireich E.J., et al. A pilot study of interleukin-2 for adult patients with acute myelogenous leukemia in first complete remission. Cancer 85 (1999) 1506-1513
    • (1999) Cancer , vol.85 , pp. 1506-1513
    • Cortes, J.E.1    Kantarjian, H.M.2    O'Brien, S.3    Giles, F.4    Keating, M.J.5    Freireich, E.J.6
  • 54
    • 0033967641 scopus 로고    scopus 로고
    • Alpha-interferon improves survival and remission duration in P-190BCR-ABL positive adult acute lymphoblastic leukemia
    • Visani G., Martinelli G., Piccaluga P., Tosi P., Amabile M., Pastano R., et al. Alpha-interferon improves survival and remission duration in P-190BCR-ABL positive adult acute lymphoblastic leukemia. Leukemia 14 (2000) 22-27
    • (2000) Leukemia , vol.14 , pp. 22-27
    • Visani, G.1    Martinelli, G.2    Piccaluga, P.3    Tosi, P.4    Amabile, M.5    Pastano, R.6
  • 55
    • 33646347162 scopus 로고    scopus 로고
    • An immune edited tumour versus a tumour edited immune system: Prospects for immune therapy of acute myeloid leukaemia
    • Chan L., Hardwick N.R., Guinn B.A., Darling D., Gaken J., Galea-Lauri J., et al. An immune edited tumour versus a tumour edited immune system: Prospects for immune therapy of acute myeloid leukaemia. Cancer Immunol Immunother 55 (2006) 1017-1024
    • (2006) Cancer Immunol Immunother , vol.55 , pp. 1017-1024
    • Chan, L.1    Hardwick, N.R.2    Guinn, B.A.3    Darling, D.4    Gaken, J.5    Galea-Lauri, J.6
  • 56
    • 35848935025 scopus 로고    scopus 로고
    • Effects of interferon-alpha on rhesus monkeys: a nonhuman primate model of cytokine-induced depression
    • Felger J.C., Alagbe O., Hu F., Mook D., Freeman A.A., Sanchez M.M., et al. Effects of interferon-alpha on rhesus monkeys: a nonhuman primate model of cytokine-induced depression. Biol Psychiatry 62 (2007) 1324-1333
    • (2007) Biol Psychiatry , vol.62 , pp. 1324-1333
    • Felger, J.C.1    Alagbe, O.2    Hu, F.3    Mook, D.4    Freeman, A.A.5    Sanchez, M.M.6
  • 57
    • 39149143029 scopus 로고    scopus 로고
    • NK cell receptors and their ligands in leukemia
    • Verheyden S., and Demanet C. NK cell receptors and their ligands in leukemia. Leukemia 22 (2008) 249-257
    • (2008) Leukemia , vol.22 , pp. 249-257
    • Verheyden, S.1    Demanet, C.2
  • 59
    • 33646060760 scopus 로고    scopus 로고
    • Immature NK cells suppress dendritic cell functions during the development of leukemia in a mouse model
    • Ebata K., Shimizu Y., Nakayama Y., Minemura M., Murakami J., Kato T., et al. Immature NK cells suppress dendritic cell functions during the development of leukemia in a mouse model. J Immunol 176 (2006) 4113-4124
    • (2006) J Immunol , vol.176 , pp. 4113-4124
    • Ebata, K.1    Shimizu, Y.2    Nakayama, Y.3    Minemura, M.4    Murakami, J.5    Kato, T.6
  • 60


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