Markers of innate immune function are associated with vitamin A stores in men

Journal of Nutrition

Volumn 139, Issue 2, 2009, Pages 377-385

  Ahmad, Shaikh M ^a,b   Haskell, Marjorie J ^a   Raqib, Rubhana ^b   Stephensen, Charles B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b ICDDRB Laboratory Sciences Division   (Bangladesh)

Author keywords

[No Author keywords available]

Indexed keywords

AGOUTI RELATED PROTEIN; BACTERIUM LIPOPOLYSACCHARIDE; BIOLOGICAL MARKER; C REACTIVE PROTEIN; EOTAXIN; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 12P40; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; NEOPTERIN; RETINOL; TUMOR NECROSIS FACTOR ALPHA; INTERLEUKIN 10; PLACEBO;

ADULT; ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; BACTERICIDAL ACTIVITY; BANGLADESH; BLOOD LEVEL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOUBLE BLIND PROCEDURE; DRUG MEGADOSE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IMMUNOREGULATION; INNATE IMMUNITY; MALE; MONOCYTE; NATURAL KILLER CELL; NATURAL KILLER T CELL; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY BURST; TH1 CELL; TH17 CELL; VISION; VITAMIN INTAKE; BLOOD; IMMUNOLOGY; METABOLISM; PHAGOCYTOSIS;

BACTERIA (MICROORGANISMS);

ADULT; DOUBLE-BLIND METHOD; HUMANS; IMMUNITY, INNATE; INTERLEUKIN-10; INTERLEUKIN-17; INTERLEUKIN-6; KILLER CELLS, NATURAL; MALE; PHAGOCYTOSIS; PLACEBOS; RESPIRATORY BURST; TH1 CELLS; VITAMIN A;

EID: 60249090145     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.108.100198     Document Type: Article

References (55)

1. Stephensen CB. Vitamin A, infection, and immune function. Annu Rev Nutr. 2001;21:167-92.
2. Chen Q, Ross AC. Retinoic acid regulates cell cycle progression and cell differentiation in human monocytic THP-1 cells. Exp Cell Res. 2004;297:68-81.
3. Jiang YJ, Xu TR, Lu B, Mymin D, Kroeger EA, Dembinski T, Yang X, Hatch GM, Choy PC. Cyclooxygenase expression is elevated in retinoic acid-differentiated U937 cells. Biochim Biophys Acta. 2003;1633:51-60.
4. Hoglen NC, Abril EA, Sauer JM, Earnest DL, McCuskey RS, Lantz RC, Mobley SA, Sipes IG. Modulation of Kupffer cell and peripheral blood monocyte activity by in vivo treatment of rats with all-trans-retinol. Liver. 1997;17:157-65.
5. Twining SS, Schulte DP, Wilson PM, Fish BL, Moulder JE. Vitamin A deficiency alters rat neutrophil function. J Nutr. 1997;127:558-65.
6. Ross AC, Stephensen CB. Vitamin A and retinoids in antiviral responses. FASEB J. 1996;10:979-85.
7. Dawson HD, Li NQ, DeCicco KL, Nibert JA, Ross AC. Chronic marginal vitamin A status reduces natural killer cell number and function in aging Lewis rats. J Nutr. 1999;129:1510-7.
8. Mathew JS, Sharma RP. Effect of all-trans-retinoic acid on cytokine production in a murine macrophage cell line. Int J Immunopharmacol. 2000;22:693-706.
9. Mehta K, McQueen T, Tucker S, Pandita R, Aggarwal BB. Inhibition by all-trans-retinoic acid of tumor necrosis factor and nitric oxide production by peritoneal macrophages. J Leukoc Biol. 1994;55:336-42.
10. Hashimoto S, Hayashi S, Yoshida S, Kujime K, Maruoka S, Matsumoto K, Gon Y, Koura T, Horie T. Retinoic acid differentially regulates interleukin-1beta and interleukin-1 receptor antagonist production by human alveolar macrophages. Leuk Res. 1998;22:1057-61.
11. Aukrust P, Muller F, Ueland T, Svardal AM, Berge RK, Froland SS. Decreased vitamin A levels in common variable immunodeficiency: vitamin A supplementation in vivo enhances immunoglobulin produc tion and downregulates inflammatory responses. Eur J Clin Invest. 2000;30:252-9.
12. Cox SE, Arthur P, Kirkwood BR, Yeboah-Antwi K, Riley EM. Vitamin A supplementation increases ratios of proinflammatory to anti-inflammatory cytokine responses in pregnancy and lactation. Clin Exp Immunol. 2006; 144:392-400.
13. Filteau SM, Morris SS, Raynes JG, Arthur P, Ross DA, Kirkwood BR, Tomkins AM, Gyapong JO. Vitamin A supplementation, morbidity, and serum acute-phase proteins in young Ghanaian children. Am J Clin Nutr. 1995;62:434-8.
14. Semba RD, Muhilal, West KP Jr, Natadisastra G, Eisinger W, Lan Y, Sommer A. Hyporetinolemia and acute phase proteins in children with and without xerophthalmia. Am J Clin Nutr. 2000;72:146-53.
15. Kongsbak K, Wahed MA, Friis H, Thilsted SH. Acute-phase protein levels, diarrhoea, Trichuris trichiura and maternal education are predictors of serum retinol: a cross-sectional study of children in a Dhaka slum, Bangladesh. Br J Nutr. 2006;96:725-34.
16. Fawzi WW, Chalmers TC, Herrera MG, Mosteller F. Vitamin A supplementation and child mortality. A meta-analysis. JAMA. 1993;269:898-903.
17. Bates CJ. Vitamin A. Lancet. 1995;345:31-5.
18. Glasziou PP, Mackerras DE. Vitamin A supplementation in infectious diseases: a meta-analysis. BMJ. 1993;306:366-70.
19. Haskell MJ, Mazumder RN, Peerson JM, Jones AD, Wahed MA, Mahalanabis D, Brown KH. Use of the deuterated-retinol-dilution tech nique to assess total-body vitamin A stores of adult volunteers consuming different amounts of vitamin A. Am J Clin Nutr. 1999;70:874-80.
20. Panel on Micronutrients, Institute of Medicine (U.S.). Food and Nutrition Board: DRI, dietary reference intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc: a report of the Panel on Micronutrients. National Academy Press, Washington, DC; 2001.
21. Ahmad SM, Haskell MJ, Raqib R, Stephensen CB. Men with low vitamin A stores respond adequately to primary yellow fever and secondary tetanus toxoid vaccination. J Nutr. 2008;138:2276-83.
22. Stephensen CB, Alvarez JO, Kohatsu J, Hardmeier R, Kennedy JI Jr, Gammon RB Jr. Vitamin A is excreted in the urine during acute infection. Am J Clin Nutr. 1994;60:388-92.
23. Furr HC, Amedee-Manesme O, Clifford AJ, Bergen HR III, Jones AD, Anderson DP, Olson JA. Vitamin A concentrations in liver determined by isotope dilution assay with tetradeuterated vitamin A and by biopsy in generally healthy adult humans. Am J Clin Nutr. 1989;49:713-6.
24. Nieman DC, Nehlsen-Cannarella SL, Fagoaga OR, Henson DA, Utter A, Davis JM, Williams F, Butterworth DE. Effects of mode and carbohydrate on the granulocyte and monocyte response to intensive, prolonged exercise. J Appl Physiol. 1998;84:1252-9.
25. Saresella M, Roda K, Speciale L, Taramelli D, Mendozzi E, Guerini F, Ferrante P. A flow cytometric method for the analysis of phagocytosis and killing by polymorphonuclear leukocytes. Ann N Y Acad Sci. 1997;832:53-61.
26. Hermann C, von Aulock S, Graf K, Hartung T. A model of human whole blood lymphokine release for in vitro and ex vivo use. J Immunol Methods. 2003;275:69-79.
27. Stephensen CB, Rasooly R, Jiang X, Ceddia MA, Weaver CT, Chandraratna RA, Bucy RP. Vitamin A enhances in vitro Th2 develop ment via retinoid X receptor pathway. J Immunol. 2002;168:4495-503.
28. Albers R, Antoine JM, Bourdet-Sicard R, Calder PC, Gleeson M, Lesourd B, Samartin S, Sanderson IR, Van Loo J, et al. Markers to measure immunomodulation in human nutrition intervention studies. Br J Nutr. 2005;94:452-81.
29. Zhao Z, Murasko DM, Ross AC. The role of vitamin A in natural killer cell cytotoxicity, number and activation in the rat. Nat Immun. 1994;13:29-41.
30. Ross AC. Vitamin A deficiency and retinoid repletion regulate the antibody response to bacterial antigens and the maintenance of natural killer cells. Clin Immunol Immunopathol. 1996;80:S63-72.
31. Vivier E, Tomasello E, Baratin M, Walzer T, Ugolini S. Functions of natural killer cells. Nat Immunol. 2008;9:503-10.
32. Motohashi S, Nakayama T. Clinical applications of natural killer T cellbased immunotherapy for cancer. Cancer Sci. 2008;99:638-45.
33. Fields AL, Soprano DR, Soprano KJ. Retinoids in biological control and cancer. J Cell Biochem. 2007;102:886-98.
34. Huiming Y, Chaomin W, Meng M. Vitamin A for treating measles in children. Cochrane Database Syst Rev. 2005;CD001479.
35. Wiysonge CS, Shey MS, Sterne JA, Brocklehurst P. Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection. Cochrane Database Syst Rev. 2005;CD003648.
36. Bresee JS, Fischer M, Dowell SF, Johnston BD, Biggs VM, Levine RS, Lingappa JR, Keyserling HL, Petersen KM, et al. Vitamin A therapy for children with respiratory syncytial virus infection: a multicenter trial in the United States. Pediatr Infect Dis J. 1996;15:777-82.
37. Seguin-Devaux C, Hanriot D, Dailloux M, Latger-Cannard V, Zannad F, Mertes PM, Longrois D, Devaux Y. Retinoic acid amplifies the host immune response to LPS through increased T lymphocytes number and LPS binding protein expression. Mol Cell Endocrinol. 2005;245:67-76.
38. Twining SS, Schulte DP, Wilson PM, Fish BL, Moulder JE. Retinol is sequestered in the bone marrow of vitamin A-deficient rats. J Nutr. 1996;126:1618-26.
39. Dufour JH, Dziejman M, Liu MT, Leung JH, Lane TE, Luster AD. IFN- gamma-inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking. J Immunol. 2002; 168:3195-204.
40. Villagomez MT, Bae SJ, Ogawa I, Takenaka M, Katayama I. Tumour necrosis factor-alpha but not interferon-gamma is the main inducer of inducible protein-10 in skin fibroblasts from patients with atopic dermatitis. Br J Dermatol. 2004;150:910-6.
41. Herder C, Hauner H, Kempf K, Kolb H, Skurk T. Constitutive and regulated expression and secretion of interferon-gamma-inducible protein 10 (IP-10/CXCL10) in human adipocytes. Int J Obes (Lond). 2006;31:403-10.
42. ter Meulen J, Sakho M, Koulemou K, Magassouba N, Bah A, Preiser W, Daffis S, Klewitz C, Bae HG, et al. Activation of the cytokine network and unfavorable outcome in patients with yellow fever. J Infect Dis. 2004;190:1821-7.
43. Querec T, Bennouna S, Alkan S, Laouar Y, Gorden K, Flavell R, Akira S, Ahmed R, Pulendran B. Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity. J Exp Med. 2006;203:413-24.
44. Monath TP, Liu J, Kanesa-Thasan N, Myers GA, Nichols R, Deary A, McCarthy K, Johnson C, Ermak T, et al. A live, attenuated recombinant West Nile virus vaccine. Proc Natl Acad Sci USA. 2006;103:6694-9.
45. Gangur V, Simons FE, Hayglass KT. Human IP-10 selectively promotes dominance of polyclonally activated and environmental antigen-driven IFN-gamma over IL-4 responses. FASEB J. 1998;12:705-13.
46. Stephensen CB, Jiang X, Freytag T. Vitamin A deficiency increases the in vivo development of IL-10-positive Th2 cells and decreases develop ment of Th1 cells in mice. J Nutr. 2004;134:2660-6.
47. Bettelli E, Oukka M, Kuchroo VK. T(H)-17 cells in the circle of immunity and autoimmunity. Nat Immunol. 2007;8:345-50.
48. Mucida D, Park Y, Kim G, Turovskaya O, Scott I, Kronenberg M, Cheroutre H. Reciprocal Th-17 and regulatory T cell differentiation mediated by retinoic acid. Science. 2007;317:256-60.
49. von Boehmer H. Oral tolerance: is it all retinoic acid? J Exp Med. 2007;204:1737-9.
50. Moore KW, de Waal Malefyt R, Coffman RL, O'Garra A. Interleukin-10 and the interleukin-10 receptor. Annu Rev Immunol. 2001;19:683-765.
51. Bleijs DA, de Waal-Malefyt R, Figdor CG, van Kooyk Y. Co-stimulation of T cells results in distinct IL-10 and TNF-alpha cytokine profiles dependent on binding to ICAM-1, ICAM-2 or ICAM-3. Eur J Immunol. 1999;29:2248-58.
52. Kim BH, Kang KS, Lee YS. Effect of retinoids on LPS-induced COX-2 expression and COX-2 associated PGE(2) release from mouse peritoneal macrophages and TNF-alpha release from rat peripheral blood mononuclear cells. Toxicol Lett. 2004;150:191-201.
53. Motomura K, Sakai H, Isobe H, Nawata H. Effects of retinoids on the production of tumour necrosis factor-alpha and nitric oxide by lipopolysaccharide-stimulated rat Kupffer cells in vitro: evidence for participation of retinoid X receptor signalling pathway. Cell Biochem Funct. 1997;15:95-101.
54. Wang X, Allen C, Ballow M. Retinoic acid enhances the production of IL-10 while reducing the synthesis of IL-12 and TNF-alpha from LPS- stimulated monocytes/macrophages. J Clin Immunol. 2007;27:193-200.
55. Reinhardt B, Jaspert R, Niedrig M, Kostner C, L'Age-Stehr J. Devel opment of viremia and humoral and cellular parameters of immune activation after vaccination with yellow fever virus strain 17D: a model of human flavivirus infection. J Med Virol. 1998;56:159-67.