Bβ15-42 (FX06) reduces pulmonary, myocardial, liver, and small intestine damage in a pig model of hemorrhagic shock and reperfusion

Critical Care Medicine

Volumn 37, Issue 2, 2009, Pages 598-605

  Roesner, Jan P ^a   Petzelbauer, Peter ^b   Koch, Alexander ^c   Tran, Nguyen ^c   Iber, Thomas ^a   Vagts, Dierk A ^a   Scheeren, Thomas W L ^a   Vollmar, Brigitte ^d   Nöldge Schomburg, Gabriele E F ^a   Zacharowski, Kai ^c  

^a ROSTOCK UNIVERSITY MEDICAL CENTER   (Germany)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

^c UNIVERSITY OF BRISTOL   (United Kingdom)

^d UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

Fibrin derived peptide; Hemorrhagic shock; Organ injury and reperfusion; Pig

Indexed keywords

FIBRIN DERIVATIVE; FIBRINE DERIVED PEPTIDE B BETA 15 42; FX 06; INTERLEUKIN 6; MYELOPEROXIDASE; TROPONIN T; UNCLASSIFIED DRUG; FIBRIN DEGRADATION PRODUCT; FIBRINOGEN BBETA (15 42); FIBRINOGEN BBETA (15-42); PEPTIDE FRAGMENT;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRYSTALLOID; EXPERIMENTAL PIG; HEART INDEX; HEART MUSCLE BLOOD FLOW; HEART MUSCLE INJURY; HEART STROKE VOLUME; HEMORRHAGIC SHOCK; INTESTINE INJURY; LIVER INJURY; LUNG BLOOD FLOW; LUNG FUNCTION; MALE; MEAN ARTERIAL PRESSURE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; REPERFUSION INJURY; RESUSCITATION; THERAPY EFFECT; TISSUE OXYGENATION; TREATMENT OUTCOME; TREATMENT RESPONSE; ANIMAL; COMPARATIVE STUDY; HEART INJURY; HUMAN; INJURY; LIVER; LUNG INJURY; PATHOPHYSIOLOGY; SMALL INTESTINE; SWINE;

ANIMALS; FIBRIN FIBRINOGEN DEGRADATION PRODUCTS; HEART INJURIES; HUMANS; INTESTINE, SMALL; LIVER; LUNG INJURY; MALE; MODELS, ANIMAL; PEPTIDE FRAGMENTS; REPERFUSION INJURY; SHOCK, HEMORRHAGIC; SWINE;

EID: 60249087722     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e3181959a12     Document Type: Article

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