Hydrogen bonding versus stacking stabilization by modified nucleobases incorporated in PNA·DNA duplexes

Biophysical Chemistry

Volumn 141, Issue 1, 2009, Pages 29-33

  Sen, Anjana ^a   Nielsen, Peter E ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Dimethyl formamide; Modified base; PNA DNA hybridization; Sequence mismatch discrimination; Thermal melting; Thermodynamics

Indexed keywords

2,6 DIAMINOPURINE; ADENINE; DOUBLE STRANDED DNA; N,N DIMETHYLFORMAMIDE; NUCLEIC ACID BASE; OLIGOMER; PEPTIDE NUCLEIC ACID; THYMINE;

AMINO ACID SUBSTITUTION; ARTICLE; BASE PAIRING; CHEMICAL MODIFICATION; CONTROLLED STUDY; DNA DENATURATION; DNA SYNTHESIS; ENTHALPY; HYBRIDIZATION; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR STABILITY; NUCLEIC ACID STRUCTURE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; THERMODYNAMICS;

BASE PAIRING; BASE SEQUENCE; DIMETHYLFORMAMIDE; DNA; HYDROGEN BONDING; NUCLEIC ACID DENATURATION; PEPTIDE NUCLEIC ACIDS; THERMODYNAMICS; THYMINE; TRANSITION TEMPERATURE;

EID: 60249084654     PISSN: 03014622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bpc.2008.12.006     Document Type: Article

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