Design and synthesis of azolopyrimidoquinolines, pyrimidoquinazolines as anti-oxidant, anti-inflammatory and analgesic activities

European Journal of Medicinal Chemistry

Volumn 44, Issue 2, 2009, Pages 609-624

  El Gazzar, A B A ^a   Youssef, M M ^b   Youssef, A M S ^b   Abu Hashem, A A ^a   Badria, F A ^c  

^a NATIONAL RESEARCH CENTRE   (Egypt)

^b CAIRO UNIVERSITY   (Egypt)

^c MANSOURA UNIVERSITY   (Egypt)

Author keywords

4 Amino derivatives; Analgesic activities; Anti inflammatory; Anti oxidant; Pyrimido 4,5 b quinolone; Thiazolo 3 ,2 :1,2 and 2,3 dihydroisoxazolo 4 ,5 :5 ,4 thiazolo 3 ,2 :1,2 pyrimido 4,5 b quinolones

Indexed keywords

2 (ACETOTHIOSEMICARBAZONE) 6 (4 CHLOROPHENYL) 10 (4 CHLOROPHENYLMETHYLENE) 3 METHYL 7,8,9,10 TETRAHYDROTHIAZOLO[3',2':1,2]PYRIMIDO[4,5 B]QUINOLIN 5 ONE; 2 CINNAMOYL 6 (4 CHLOROPHENYL) 10 (4 CHLOROPHENYLMETHYLENE) 3 METHYL 7,8,9,10 TETRAHYDROTHIAZOLO[3',2':1,2]PYRIMIDO[4,5 B]QUINOLIN 5 ONE; 2,2' AZINOBIS(3 ETHYLBENZOTHIAZOLINE 6 SULFONIC ACID); 5 (4 CHLOROPHENYL) 9 (4 CHLOROPHENYLMETHYLENE) 5,10 DIHYDRO 2 THIOXO 6,7,8,9 TETRAHYDROPYRIMIDO[4,5 B]QUINOLIN 4 ONE; 5 (4 CHLOROPHENYL) 9 (CHLOROPHENYLMETHYLENE) 4 PIPERAZINO 2 METHYLTHIO 6,7,8,9 TETRAHYDROPYRIDO[4,5 B]QUINOLINE; 5 (4 METHOXYPHENYL) 9 (4 METHOXYPHENYLMETHYLENE) 5,10 DIHYDRO 2 THIOXO 6,7,8,9 TETRAHYDROPYRIMIDO[4,5 B]QUINOLIN 4 ONE; 5,10 DIHYDRO 5 PHENYL 9 (PHENYLMETHYLENE) 2 THIOXO 6,7,8,9 TETRAHYDROPYRIMIDO[4,5 B]QUINOLIN 4 ONE; 6 (4 CHLOROPHENYL) 10 (4 CHLOROPHENYLMETHYLENE) 2 PHENYLMETHYLENE 7,8,9,10 TETRAHYDROTHIAZOLO[3',2':1,2]PYRIMIDO[4,5 B]QUINOLINE 3,5 DIONE; BLEOMYCIN; CARRAGEENAN; DICLOFENAC; QUINAZOLINE DERIVATIVE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DNA DAMAGE; DRUG DESIGN; DRUG SYNTHESIS; FEMALE; HEMOLYSIS; INFRARED SPECTROSCOPY; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PAW EDEMA; PROTON NUCLEAR MAGNETIC RESONANCE; RAT;

ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; BRAIN; DNA DAMAGE; DRUG DESIGN; EDEMA; ERYTHROCYTES; HEMOLYSIS; KIDNEY; QUINOLINES; RATS; SPECTRUM ANALYSIS;

EID: 60149105200     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.03.022     Document Type: Article

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