-
1
-
-
0027983761
-
Roxithromycin. An update of its antimicrobial activity, pharmacoinetic properties and therapeutic use
-
Markcham A., Faulds D. (1994): Roxithromycin. An update of its antimicrobial activity, pharmacoinetic properties and therapeutic use. Drugs, 48, 297-326.
-
(1994)
Drugs
, vol.48
, pp. 297-326
-
-
Markcham, A.1
Faulds, D.2
-
2
-
-
0024535916
-
Roxithromycin. A review of its antibacterial activity, pharmacokinetic properties and clinical efficacy
-
Young R.A. Gonzalez J.P., Sorkin E.M. (1989): Roxithromycin. A review of its antibacterial activity, pharmacokinetic properties and clinical efficacy. Drugs, 37, 8-41.
-
(1989)
Drugs
, vol.37
, pp. 8-41
-
-
Young, R.A.1
Gonzalez, J.P.2
Sorkin, E.M.3
-
3
-
-
0033670712
-
Effects of macrolide antibiotics on CYP3A expression in human and rat hepatocytes: Interspecies differences in response to troleandomycin
-
Ledirac N., de Sousa G., Fontaine F., Agouridas C., Gugenheim J., Lorenzon G., Rahmani R. (2000): Effects of macrolide antibiotics on CYP3A expression in human and rat hepatocytes: interspecies differences in response to troleandomycin. Drug Metab. Dispos., 28, 1391-1393.
-
(2000)
Drug Metab. Dispos
, vol.28
, pp. 1391-1393
-
-
Ledirac, N.1
de Sousa, G.2
Fontaine, F.3
Agouridas, C.4
Gugenheim, J.5
Lorenzon, G.6
Rahmani, R.7
-
4
-
-
0031769798
-
Comparative studies of in vitro inhibition of cytochrome P450 3A4-dependent testosterone 6beta-hydroxylation by roxithromycin and its metabolites, troleandomycin, and erythromycin
-
Yamazaki H., Shimada T. (1989): Comparative studies of in vitro inhibition of cytochrome P450 3A4-dependent testosterone 6beta-hydroxylation by roxithromycin and its metabolites, troleandomycin, and erythromycin. Drug Metab. Dispos., 26, 1053-1057.
-
(1989)
Drug Metab. Dispos
, vol.26
, pp. 1053-1057
-
-
Yamazaki, H.1
Shimada, T.2
-
5
-
-
0142106303
-
Transporter-enzyme interactions: Implications for predicting drug - drug interactions from in vitro data
-
Benet L.Z., Cummins C.L., Wu C.Y. (2003): Transporter-enzyme interactions: implications for predicting drug - drug interactions from in vitro data. Curr. Drug Metab., 4, 393-398.
-
(2003)
Curr. Drug Metab
, vol.4
, pp. 393-398
-
-
Benet, L.Z.1
Cummins, C.L.2
Wu, C.Y.3
-
6
-
-
0031944723
-
Overlapping substrate specificities of cyt-ochrome P450 3A and P-glyco-protein for a novel cysteine protease inhibitor
-
Zhang Y., Guo X., Lin E.T., Benet L.Z. (1998): Overlapping substrate specificities of cyt-ochrome P450 3A and P-glyco-protein for a novel cysteine protease inhibitor. Drug Metab. Dispos., 26, 360-366.
-
(1998)
Drug Metab. Dispos
, vol.26
, pp. 360-366
-
-
Zhang, Y.1
Guo, X.2
Lin, E.T.3
Benet, L.Z.4
-
7
-
-
0038725719
-
Experimental estimation of the role of P-Glycoprotein in the pharmacokinetic behaviour of telithromycin, a novel ketolide, in comparison with roxithromycin and other macrolides using the Caco-2 cell model
-
Pachot J.I., Botham R.P., Haegele K.D., Hwang K. (2003): Experimental estimation of the role of P-Glycoprotein in the pharmacokinetic behaviour of telithromycin, a novel ketolide, in comparison with roxithromycin and other macrolides using the Caco-2 cell model. J. Pharm. Pharm. Sci., 6, 1-12.
-
(2003)
J. Pharm. Pharm. Sci
, vol.6
, pp. 1-12
-
-
Pachot, J.I.1
Botham, R.P.2
Haegele, K.D.3
Hwang, K.4
-
8
-
-
0023192697
-
Studies on the central effects of the HI-antagonist, loratadine
-
Bradley C.M., Nicholson A.N. (1987): Studies on the central effects of the HI-antagonist, loratadine. Eur. J. Clin. Pharmacol., 32, 419-421.
-
(1987)
Eur. J. Clin. Pharmacol
, vol.32
, pp. 419-421
-
-
Bradley, C.M.1
Nicholson, A.N.2
-
9
-
-
0026540567
-
Effects of loratadine and cetirizine on actual driving and psychometric test performance, and EEG during d-riving
-
Ramaekers J.G., Uiterwijk M.M., O'Hanlon J.F. (1992): Effects of loratadine and cetirizine on actual driving and psychometric test performance, and EEG during d-riving. Eur. J. Clin. Pharmacol., 42, 363-369.
-
(1992)
Eur. J. Clin. Pharmacol
, vol.42
, pp. 363-369
-
-
Ramaekers, J.G.1
Uiterwijk, M.M.2
O'Hanlon, J.F.3
-
10
-
-
14444276731
-
-
Kay G.G., Berman B., Mockoviak S.H., Morris C.E., Reeves D., Starbuck V., Sukenik E., Harris A.G. (1997): Initial and steady-state effects of diphenhydramine and loratadine on sedation, cognition, mood, and psychomotor performance. Arch. Intern. Med., 157, 2350-2356.
-
Kay G.G., Berman B., Mockoviak S.H., Morris C.E., Reeves D., Starbuck V., Sukenik E., Harris A.G. (1997): Initial and steady-state effects of diphenhydramine and loratadine on sedation, cognition, mood, and psychomotor performance. Arch. Intern. Med., 157, 2350-2356.
-
-
-
-
12
-
-
0033917795
-
Efficacy and tolerability of loratadine versus fexofenadine in the treatment of seasonal allergic rhinitis: Adouble-blind comparison with crossover treatment of nonresponders
-
Prenner B.M., Capano D., Harris A.G. (2000): Efficacy and tolerability of loratadine versus fexofenadine in the treatment of seasonal allergic rhinitis: adouble-blind comparison with crossover treatment of nonresponders. Clin. Ther., 22, 760-769.
-
(2000)
Clin. Ther
, vol.22
, pp. 760-769
-
-
Prenner, B.M.1
Capano, D.2
Harris, A.G.3
-
13
-
-
0024556615
-
Loratadine, a preliminary review of its pharmacodynamic properties and therapeutic efficacy
-
Clissold S.P., Sorkin E.M., Goa K.L. (1989): Loratadine, a preliminary review of its pharmacodynamic properties and therapeutic efficacy. Drugs, 37, 42-57.
-
(1989)
Drugs
, vol.37
, pp. 42-57
-
-
Clissold, S.P.1
Sorkin, E.M.2
Goa, K.L.3
-
14
-
-
0023544915
-
Pharmacokinetics and dose proportionality of loratadine
-
Hilbert J., Radwanski E., Weglein R., Luc V., Perentesis G., Symchowicz S., Zampaglione N. (1987): Pharmacokinetics and dose proportionality of loratadine. J. Clin. Pharmacol., 27, 694-698.
-
(1987)
J. Clin. Pharmacol
, vol.27
, pp. 694-698
-
-
Hilbert, J.1
Radwanski, E.2
Weglein, R.3
Luc, V.4
Perentesis, G.5
Symchowicz, S.6
Zampaglione, N.7
-
15
-
-
0033999939
-
Preclinical pharmacology of destoratadine, a selective and nonsedating histamine H1 receptor antagonist. 1st communication: Receptor selectivity, antihistaminic activity, and antiallergenic effects
-
Kreutner W., Hey J.A., Anthes J., Barnett A., Young S., Tozzi S. (2000): Preclinical pharmacology of destoratadine, a selective and nonsedating histamine H1 receptor antagonist. 1st communication: receptor selectivity, antihistaminic activity, and antiallergenic effects. Arzneimittelforschung, 50, 345-352.
-
(2000)
Arzneimittelforschung
, vol.50
, pp. 345-352
-
-
Kreutner, W.1
Hey, J.A.2
Anthes, J.3
Barnett, A.4
Young, S.5
Tozzi, S.6
-
16
-
-
0035137186
-
The pharmacologic profile of desloratadine: A review
-
Henz B.M. (2001): The pharmacologic profile of desloratadine: a review. Allergy, 56 Suppl 65, 7-13.
-
(2001)
Allergy
, vol.56
, Issue.SUPPL. 65
, pp. 7-13
-
-
Henz, B.M.1
-
17
-
-
0030048830
-
Identification of human liver cytochrome P450 enzymes that metabolize the nonsedating anti-histamine loratadine. Formation of descarboethoxyloratadine by CYP3A4 and CYP2D6
-
Yumibe N., Huie K., Chen K.J., Snow M., Clement R.P., Cayen M.N. (1996): Identification of human liver cytochrome P450 enzymes that metabolize the nonsedating anti-histamine loratadine. Formation of descarboethoxyloratadine by CYP3A4 and CYP2D6. Biochem. Pharmacol., 51, 165-172.
-
(1996)
Biochem. Pharmacol
, vol.51
, pp. 165-172
-
-
Yumibe, N.1
Huie, K.2
Chen, K.J.3
Snow, M.4
Clement, R.P.5
Cayen, M.N.6
-
18
-
-
0034943050
-
Evaluation of the interaction of loratadine and desloratadine with P-glycoprotein
-
Wang E.J., Casciano C.N., Clement R.P., Johnson W.W. (2001): Evaluation of the interaction of loratadine and desloratadine with P-glycoprotein. Drug Metab. Dispos., 29, 1080-1083.
-
(2001)
Drug Metab. Dispos
, vol.29
, pp. 1080-1083
-
-
Wang, E.J.1
Casciano, C.N.2
Clement, R.P.3
Johnson, W.W.4
-
19
-
-
0031765907
-
Role of P-glycoprotein and cytochrome P450 3A in limiting oral absorption of peptides and peptidomimetics
-
Wacher V.J., Silverman J.A., Zhang Y., Benet L.Z. (1998): Role of P-glycoprotein and cytochrome P450 3A in limiting oral absorption of peptides and peptidomimetics. J. Pharm. Sci., 87, 1322-1330.
-
(1998)
J. Pharm. Sci
, vol.87
, pp. 1322-1330
-
-
Wacher, V.J.1
Silverman, J.A.2
Zhang, Y.3
Benet, L.Z.4
-
20
-
-
0033007704
-
Effects of intestinal CYP3A4 and P-glycoprotein on oral drug absorption; theoretical approach
-
Ito K., Kusuhara H., Sugiyama Y. (1999): Effects of intestinal CYP3A4 and P-glycoprotein on oral drug absorption; theoretical approach. Pharm. Res., 16, 225-231.
-
(1999)
Pharm. Res
, vol.16
, pp. 225-231
-
-
Ito, K.1
Kusuhara, H.2
Sugiyama, Y.3
-
21
-
-
0025168996
-
Identification of the rabbit and human cytochromes P-450IIIA as the major enzymes involved in the N-demethylation of diltiazem
-
Pichard L., Gillet G., Fabre I., Dalet-Beluche I., Bonfils C., Thenot J.P., Maurel P. (1990): Identification of the rabbit and human cytochromes P-450IIIA as the major enzymes involved in the N-demethylation of diltiazem. Drug Metab. Dispos., 18, 711-719.
-
(1990)
Drug Metab. Dispos
, vol.18
, pp. 711-719
-
-
Pichard, L.1
Gillet, G.2
Fabre, I.3
Dalet-Beluche, I.4
Bonfils, C.5
Thenot, J.P.6
Maurel, P.7
-
22
-
-
0031971093
-
Steady-state pharmacokinetics and electrocardiographic pharmacodynamics of clarithromycin and loratadine after individual or concomitant administration
-
Carr R.A., Edmonds A., Shi H., Locke C.S., Gustavson L.E., Craft J.C., Harris S.I., Palmer R. (1998): Steady-state pharmacokinetics and electrocardiographic pharmacodynamics of clarithromycin and loratadine after individual or concomitant administration. Antimicrob. Agents Chemother, 42, 1176-1180.
-
(1998)
Antimicrob. Agents Chemother
, vol.42
, pp. 1176-1180
-
-
Carr, R.A.1
Edmonds, A.2
Shi, H.3
Locke, C.S.4
Gustavson, L.E.5
Craft, J.C.6
Harris, S.I.7
Palmer, R.8
-
23
-
-
0034533744
-
Evaluation of the pharmacokinetics and electrocardiographic pharmacodynamics of loratadine with concomitant administration of ketoconazole or cimetidine
-
Kosoglou T., Salfi M., Lim J.M., Batra V.K., Cayen M.N., Affrime M.B. (2000): Evaluation of the pharmacokinetics and electrocardiographic pharmacodynamics of loratadine with concomitant administration of ketoconazole or cimetidine. Br. J. Clin. Pharmacol., 50, 581-589.
-
(2000)
Br. J. Clin. Pharmacol
, vol.50
, pp. 581-589
-
-
Kosoglou, T.1
Salfi, M.2
Lim, J.M.3
Batra, V.K.4
Cayen, M.N.5
Affrime, M.B.6
-
24
-
-
1542503913
-
Reliable and specific high-performance liquid chromatographic method for simultaneous determination of loratadine and its metabolite in human plasma
-
Yin O.Q., Shi X., Chow M.S. (2003): Reliable and specific high-performance liquid chromatographic method for simultaneous determination of loratadine and its metabolite in human plasma. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci., 796, 165-172.
-
(2003)
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci
, vol.796
, pp. 165-172
-
-
Yin, O.Q.1
Shi, X.2
Chow, M.S.3
-
25
-
-
4143091474
-
Rapid determination of loratadine in small volume plasma samples by high-performance liquid chromatography with fluorescence detection
-
Amini H., Ahmadiani A. (2004): Rapid determination of loratadine in small volume plasma samples by high-performance liquid chromatography with fluorescence detection. J. Chromatogr. B. Analyt. Technol. Biomed. Life ScI. 809, 227-230.
-
(2004)
J. Chromatogr. B. Analyt. Technol. Biomed. Life ScI
, vol.809
, pp. 227-230
-
-
Amini, H.1
Ahmadiani, A.2
-
26
-
-
0036175307
-
Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4
-
Cummins C.L., Jacobsen W., Benet L.Z. (2002): Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4. J. Pharmacol. Exp. Ther., 300, 1036-1045.
-
(2002)
J. Pharmacol. Exp. Ther
, vol.300
, pp. 1036-1045
-
-
Cummins, C.L.1
Jacobsen, W.2
Benet, L.Z.3
-
27
-
-
0033772113
-
Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors
-
Wolozin B., Kellman W., Ruosseau P., Celesia G.G., Siegel G. (2000): Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors. Arch. Neurol., 10, 1439-1443.
-
(2000)
Arch. Neurol
, vol.10
, pp. 1439-1443
-
-
Wolozin, B.1
Kellman, W.2
Ruosseau, P.3
Celesia, G.G.4
Siegel, G.5
-
28
-
-
0026598851
-
-
Kaminsky L.S., Fasco M.J. (1991): Small intestinal cytochromes P450. Crit. Rev. Toxocol., 21, 407-422.
-
Kaminsky L.S., Fasco M.J. (1991): Small intestinal cytochromes P450. Crit. Rev. Toxocol., 21, 407-422.
-
-
-
|