Oral budesonide for the therapy of post-liver transplant de novo inflammatory bowel disease: A case series and systematic review of the literature

Inflammatory Bowel Diseases

Volumn 14, Issue 12, 2008, Pages 1695-1700

  Barritt IV, A Sidney ^a   Zacks, Steven L ^a   Rubinas, Tara C ^a   Herfarth, Hans H ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Colitis; Crohn's disease; Inflammatory bowel disease; Liver transplantation; Ulcerative colitis

Indexed keywords

BUDESONIDE; CALCINEURIN INHIBITOR; CYCLOSPORIN; GANCICLOVIR; MESALAZINE; METRONIDAZOLE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; RAPAMYCIN; TACROLIMUS; IMMUNOSUPPRESSIVE AGENT;

ADULT; ANOREXIA; ARTICLE; ASCENDING COLON; AUTOIMMUNE HEPATITIS; BLOODY DIARRHEA; CASE REPORT; CASE STUDY; CAUCASIAN; CHRONIC KIDNEY FAILURE; CLINICAL FEATURE; COLON BIOPSY; COLONOSCOPY; CROHN DISEASE; CYTOMEGALOVIRUS INFECTION; DIARRHEA; DISEASE COURSE; DISEASE SEVERITY; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG MEGADOSE; DRUG RESPONSE; DRUG SUBSTITUTION; DRUG TREATMENT FAILURE; DRUG WITHDRAWAL; ENTERITIS; FEMALE; FOLLOW UP; GRAFT REJECTION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INFLAMMATION; INFORMATION RETRIEVAL; KIDNEY FAILURE; LIQUID FECES; LIVER FAILURE; LIVER TRANSPLANTATION; MALE; MEDLINE; NAUSEA; PRIMARY BILIARY CIRRHOSIS; PRIMARY SCLEROSING CHOLANGITIS; PRIORITY JOURNAL; REMISSION; SIGMOID; ULCERATIVE COLITIS; UREMIA; VOMITING; WEIGHT REDUCTION; CYTOMEGALOVIRUS; MIDDLE AGED; ORAL DRUG ADMINISTRATION; PATHOGENICITY; POSTOPERATIVE COMPLICATION; VIROLOGY;

ADMINISTRATION, ORAL; BUDESONIDE; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INFLAMMATORY BOWEL DISEASES; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; POSTOPERATIVE COMPLICATIONS;

EID: 59849120866     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1002/ibd.20528     Document Type: Article

References (37)

1. Wong NA, Bathgate AJ, Bellamy CO. Colorectal disease in liver allograft recipients - a clinicopathological study with follow-up. Eur J Gastroenterol Hepatol. 2002;14:231-623.
2. Ginsburg PM, Thuluvath PJ. Diarrhea in liver transplant recipients: etiology and management. Liver Transpl. 2005;11:881-890.
3. Cox GJ, Matsui SM, Lo RS, et al. Etiology and outcome of diarrhea after marrow transplantation: a prospective study. Gastroenterology. 1994; 107:1398-1407.
4. LaRusso NF, Wiesner RH, Ludwig J, et al. Current concepts. Primary sclerosing cholangitis. N Engl J Med. 1984;310:899-903.
5. Zeuzem S. Gut-liver axis. Int J Colorectal Dis. 2000;15:59-82.
6. Dvorchik I, Subotin M, Demetris AJ, et al. Effect of liver transplantation on inflammatory bowel disease in patients with primary sclerosing cholangitis. Hepatology. 2002;35:380-384.
7. Miki C, Harrison JD, Gunson BK, et al. Inflammatory bowel disease in primary sclerosing cholangitis: an analysis of patients undergoing liver transplantation. Br J Surg. 1995;82:1114-1117.
8. Ho GT, Seddon AJ, Therapondos G, et al. The clinical course of ulcerative colitis after orthotopic liver transplantation for primary sclerosing cholangitis: further appraisal of immunosuppression post transplantation. Eur J Gastroenterol Hepatol. 2005;17:1379-385.
9. Papatheodoridis GV, Hamilton M, Mistry PK, et al. Ulcerative colitis has an aggressive course after orthotopic liver transplantation for primary sclerosing cholangitis. Gut. 1998;43:639-644.
10. MacLean AR, Lilly L, Cohen Z, et al. Outcome of patients undergoing liver transplantation for primary sclerosing cholangitis. Dis Colon Rectum. 2003;46:1124-1128.
11. Befeler AS, Lissoos TW, Schiano TD, et al. Clinical course and management of inflammatory bowel disease after liver transplantation. Transplantation. 1998;65:393-396.
12. Halsey K, Reichelderfer M, Callicott RW, et al. Collagenous colitis presenting after orthotopic liver transplantation for alpha-1-antitrypsin deficiency. Dig Dis Sci. 2007;52:217-219.
13. Khan S, Lichtman SN, Reyes J, et al. Ulcerative colitis after liver transplant and immunosuppression. J Pediatr Gastroenterol Nutr. 1999; 28:206-209.
14. Lal S, Steinhart AH. Infliximab for ulcerative colitis following liver transplantation. Eur J Gastroenterol Hepatol. 2007;19:277-280.
15. Klotz U, Schwab M. Topical delivery of therapeutic agents in the treatment of inflammatory bowel disease. Adv Drug Deliv Rev. 2005; 57:267-279.
16. Spencer CM, McTavish D. Budesonide. A review of its pharmacological properties and therapeutic efficacy in inflammatory bowel disease. Drugs. 1995;50:854-872.
17. Lofberg R, Danielsson A, Suhr O, et al. Oral budesonide versus prednisolone in patients with active extensive and left-sided ulcerative colitis. Gastroenterology. 1996;110:1713-1718.
18. Keller R, Stoll R, Foerster EC, et al. Oral budesonide therapy for steroid-dependent ulcerative colitis: a pilot trial. Aliment Pharmacol Ther. 1997;11:1047-1052.
19. Haagsma EB, Van Den Berg AP, Kleibeuker JH, et al. Inflammatory bowel disease after liver transplantation: the effect of different immunosuppressive regimens. Aliment Pharmacol Ther. 2003;18:33-44.
20. Worns MA, Lohse AW, Neurath MF, et al. Five cases of de novo inflammatory bowel disease after orthotopic liver transplantation. Am J Gastroenterol. 2006;101:1931-1937.
21. Kane SV, Schoenfeld P, Sandborn WJ, et al. The effectiveness of budesonide therapy for Crohn's disease. Aliment Pharmacol Ther. 2002; 16:1509-1517.
22. Otley A, Steinhart AH. Budesonide for induction of remission in Crohn's disease. Cochrane Database Syst Rev. 2005:CD000296.
23. Bonderup OK, Hansen JB, Birket-Smith L, et al. Budesonide treatment of collagenous colitis: a randomised, double blind, placebo controlled trial with morphometric analysis. Gut. 2003;52:248-251.
24. Lanyi B, Dries V, Dienes HP, et al. Therapy of prednisone-refractory collagenous colitis with budesonide. Int J Colorectal Dis. 1999;14:58-61.
25. Chande N, McDonald JW, MacDonald JK. Interventions for treating collagenous colitis. Cochrane Database Syst Rev. 2006:CD003575.
26. Andus T, Gross V, Caesar I, et al. Replacement of conventional glucocorticoids by oral pH-modified release budesonide in active and inactive Crohn's disease: results of an open, prospective, multicenter trial. Dig Dis Sci. 2003;48:373-378.
27. Cortot A, Colombel JF, Rutgeerts P, et al. Switch from systemic steroids to budesonide in steroid dependent patients with inactive Crohn's disease. Gut. 2001;48:186-190.
28. Shaked A, Colonna JO, Goldstein L, et al. The interrelation between sclerosing cholangitis and ulcerative colitis in patients undergoing liver transplantation. Ann Surg. 1992;215:598-603; discussion 604-605.
29. Cuoco L, Tursi A, Cammarota G, et al. Onset of ulcerative colitis during immunosuppressive therapy for liver transplantation. Am J Gastroenterol. 1997;92:2134-2135.
30. Riley TR, Schoen RE, Lee RG, et al. A case series of transplant recipients who despite immunosuppression developed inflammatory bowel disease. Am J Gastroenterol. 1997;92:279-282.
31. Chalasani N, Smallwood G. Idiopathic ulcerative colitis in patients with primary sclerosing colitis undergoing orthotopic liver transplantation (OLT). Am J Gastroenterol. 1998;93:481-482.
32. Safadi R, Ilan Y, Galun E, et al. Primary sclerosing cholangitis and liver transplantation. Transplant Proc. 1999;31:1896.
33. Ramji A, Owen DA, Erb SR, et al. Post-liver transplant Crohn's disease: graft tolerance but not self-tolerance?. Dig Dis Sci. 2002;47:522-527.
34. van de Vrie W, de Man RA, van Buuren HR, et al. Inflammatory bowel disease and liver transplantation for primary sclerosing cholangitis. Eur J Gastroenterol Hepatol. 2003;15:657-663.
35. Papadakis KA, Matuk R, Abreu MT, et al. Crohn's ileitis after liver transplantation from a living related donor with Crohn's disease. Gut. 2004;53:1389-1390.
36. Verdonk RC, Dijkstra G, Haagsma EB, et al. Inflammatory bowel disease after liver transplantation: risk factors for recurrence and de novo disease. Am J Transplant. 2006;6:1422-1429.
37. Cholongitas E, Papatheodoridis GV, Zappoli P, et al. Combined HLADR and -DQ disparity is associated with a stable course of ulcerative colitis after liver transplantation for primary sclerosing cholangitis. Liver Transpl. 2007;13:552-557.