Five cases of de novo inflammatory bowel disease after orthotopic liver transplantation

American Journal of Gastroenterology

Volumn 101, Issue 8, 2006, Pages 1931-1937

  Wörns, Marcus A ^a   Lohse, Ansgar W ^b   Neurath, Markus F ^a   Croxford, Andrew ^a   Otto, Gerd ^a   Kreft, Andreas ^a   Galle, Peter R ^a   Kanzler, Stephan ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOSALICYLIC ACID DERIVATIVE; ANTIINFLAMMATORY AGENT; AZATHIOPRINE; BUDESONIDE; CORTICOSTEROID; CYCLOPHOSPHAMIDE; CYCLOSPORIN; GANCICLOVIR; HEPATITIS B ANTIBODY; IMMUNOSUPPRESSIVE AGENT; LAMIVUDINE; MESALAZINE; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; RAPAMYCIN; TACROLIMUS;

ABDOMINAL CRAMP; ACUTE GRAFT REJECTION; ADOLESCENT; ADULT; ANTIPHOSPHOLIPID SYNDROME; ARTICLE; ATAXIA; AUTOIMMUNE HEPATITIS; BLOODY DIARRHEA; CLINICAL ARTICLE; CLINICAL EXAMINATION; CORTICOSTEROID THERAPY; CROHN DISEASE; CYTOMEGALOVIRUS INFECTION; DIABETES MELLITUS; DISEASE EXACERBATION; DRUG DOSE REDUCTION; DRUG SUBSTITUTION; DRUG WITHDRAWAL; ENTERITIS; FEMALE; HEMORRHAGIC COLITIS; HEPATITIS B; HISTOCHEMISTRY; HUMAN; HYPOTHYROIDISM; IMMUNE DYSREGULATION; IMMUNOSUPPRESSIVE TREATMENT; INFECTION PREVENTION; LABORATORY TEST; LIVER CIRRHOSIS; LIVER GRAFT REJECTION; LIVER ISCHEMIA; LIVER TRANSPLANTATION; MALE; MONOTHERAPY; NEUROLOGIC DISEASE; POLYNEUROPATHY; PRIORITY JOURNAL; RECTUM DISEASE; RELAPSE; REMISSION; REOPERATION; SYSTEMIC LUPUS ERYTHEMATOSUS; SYSTEMIC THERAPY; TREATMENT DURATION; TREATMENT INDICATION; ULCERATIVE COLITIS; VIRUS HEPATITIS; WILSON DISEASE;

ADOLESCENT; BIOPSY; COLITIS, ULCERATIVE; FEMALE; HUMANS; IMMUNOSUPPRESSION; LIVER TRANSPLANTATION; MALE; MIDDLE AGED;

EID: 33746692487     PISSN: 00029270     EISSN: 15720241     Source Type: Journal    
DOI: 10.1111/j.1572-0241.2006.00624.x     Document Type: Article

References (42)

1. Papatheodoridis GV, Hamilton M, Mistry PK, et al. Ulcerative colitis has an aggressive course after orthotopic liver transplantation for primary sclerosing cholangitis. Gut 1998;43:639-44.
2. Befeler AS, Lissoos TW, Schiano TD, et al. Clinical course and management of inflammatory bowel disease after liver transplantation. Transplantation 1998;65:393-6.
3. Gavaler JS, Delemos B, Belle SH, et al. Ulcerative colitis disease activity as subjectively assessed by patient-completed questionnaires following orthotopic liver transplantation for sclerosing cholangitis. Dig Dis Sci 1991;36:321-8.
4. Stephens J, Goldstein R, Crippin J, et al. Effects of orthotopic liver transplantation and immunosuppression on inflammatory bowel disease in primary sclerosing cholangitis patients. Transplant Proc 1993;25:1122-3.
5. Shaked A, Colonna JO, Goldstein L, et al. The interrelation between sclerosing cholangitis and ulcerative colitis in patients undergoing liver transplantation. Ann Surg 1992;215:598-603.
6. van de Vrie W, de Man RA, van Buuren HR, et al. Inflammatory bowel disease and liver transplantation for primary sclerosing cholangitis. Eur J Gastroenterol Hepatol 2003;15:657-63.
7. LaRusso NF, Wiesner RH, Ludwig J, et al. Current concepts. Primary sclerosing cholangitis. N Engl J Med 1984;310:899-903.
8. Czaja AJ, Davis GL, Ludwig J, et al. Autoimmune features as determinants of prognosis in steroid-treated chronic active hepatitis of uncertain etiology. Gastroenterology 1983;85:713-7.
9. Strober W, James SP. The immunologic basis of inflammatory bowel disease. J Clin Immunol 1986;6:415-32.
10. MacDonald TT, Murch SH. Aetiology and pathogenesis of chronic inflammatory bowel disease. Baillieres Clin Gastroenterol 1994;8:1-34.
11. Zeuzem S. Gut-liver axis. Int J Colorectal Dis 2000;15:59-82.
12. Riley TR, Schoen RE, Lee RG, et al. A case series of transplant recipients who despite immunosuppression developed inflammatory bowel disease. Am J Gastroenterol 1997;92:279-82.
13. Cuoco L, Tursi A, Cammarota G, et al. Onset of ulcerative colitis during immunosuppressive therapy for liver transplantation. Am J Gastroenterol 1997;92:2134-5.
14. Ramji A, Owen DA, Erb SR, et al. Post-liver transplant Crohn's disease: Graft tolerance but not self-tolerance? Dig Dis Sci 2002;47:522-7.
15. Haagsma EB, Van Den Berg AP, Kleibeuker JH, et al. Inflammatory bowel disease after liver transplantation: The effect of different immunosuppressive regimens. Aliment Pharmacol Ther 2003;18:33-44.
16. Cox GJ, Matsui SM, Lo RS, et al. Etiology and outcome of diarrhea after marrow transplantation: A prospective study. Gastroenterology 1994;107:1398-407.
17. Altiparmak MR, Trablus S, Pamuk ÖN, et al. Diarrhoea following renal transplantation. Clin Transplant 2002;16:212-6.
18. Helderman JH. Prophylaxis and treatment of gastrointestinal complications following transplantation. Clin Transplant 2001;15(suppl 4):29-35.
19. Ginsburg PM, Thuluvath PJ. Diarrhea in liver transplant recipients: Etiology and management. Liver Transpl 2005;8:881-90.
20. Rubin RH. Gastrointestinal infectious disease complications following transplantation and their differentiation from immunosuppressant-induced gastrointestinal toxicities. Clin Transpl 2001;15(suppl 4):11-22.
21. Ayata G, Gordon FD, Lweis WD, et al. Cryptogenic cirrhosis: Clinicopathologic findings at and after liver transplantation. Hum Pathol 2002;33:1098-104.
22. Morozov SG, Usanova MP, Poleshchuk VV, et al. Nervous tissue protein autoantibodies in hepatolenticular degeneration. Zh Nevrol Psikhiatr Im SS Korsakova 2001;101:37-9.
23. Lohse AW, Obermayer-Straub P, Gerken G, et al. Development of cytochrome P450 2D6-specific LKM-autoantibodies following liver transplantation for Wilson's disease-possible association with a steroid-resistant tranplant rejection episode. J Hepatol 1999;31:149-55.
24. Wahbeh G, Hupertz V, Hallowell S, et al. Idiopathic colitis following cardiac transplantation: Three pediatric cases. Pediatr Transplant 2003;7:464-8.
25. Siegel CA, Sands BE. Review article: Practical management of inflammatory bowel disease patients taking immunomodulators. Aliment Pharmacol Ther 2005;22:1-16.
26. Van Assche G, D'Haens G, Noman M. Randomized, double-blind comparison of 4 mg/kg versus 2 mg/kg intravenous cyclosporine in severe ulcerative colitis. Gastroenterology 2003;123:1025-31.
27. Passfall J, Distler A, Riecken EO, et al. Development of ulcerative colitis under the immunosuppressive effect of cyclosporine. Clin Investig 1992;70:611-3.
28. Collins RHJr, Sackler M, Pitcher CJ, et al. Immune reconstitution with donor-derived memory/effector T cells after orthotopic liver transplantation. Exp Hematol 1997;25:147-59.
29. Sonwalkar SA, James RM, Ahmad T, et al. Fulminant Crohn's colitis after allogeneic stem cell transplantation. Gut 2003;52:1518-21.
30. Holtmann MH, Neurath MF. Transplanting the genetic susceptibility to Crohn's disease. Gut 2003;52:1394-6.
31. Niessner M, Volk BA. Phenotypic and immunoregulatory analysis of intestinal T-cells in patients with inflammatory bowel disease: Evaluation of an in vitro model. Eur J Clin Invest 1995;25:155-64.
32. Senju M, Hulstaert F, Lowder J, et al. Flow cytometric analysis of peripheral blood lymphocytes in ulcerative colitis and Crohn's disease. Gut 1991;32:779-83.
33. James SP. Remission of Crohn's disease after human immunodeficiency virus infection. Gastroenterology 1988;95:1667-9.
34. Teo M, Rodgers NG, Cummins AG. Development of ulcerative colitis despite long-term immunosuppression with cyclosporin and azathioprine in an Australian Aborigine. J Gastroenterol Hepatol 2002;17:1130-1.
35. Damoiseaux JG, Breda Vriesman PJ. Cyclosporin A-induced autoimmunity: The result of defective de novo T-cell development. Folia Biol (Praha) 1998;44:1-9.
36. Czaja AJ. Autoimmune hepatitis after liver transplantation and other lessons of self-intolerance. Liver Transpl 2002;8:505-13.
37. Bogdanos DP, Choudhuri K, Vergani D. Molecular mimicry and autoimmune liver disease: Virtuous intentions, malign consequences. Liver 2001;21:225-32.
38. Vergani D, Mieli-Vergani G. Autoimmunity after liver transplantation. Hepatology 2002;36:271-6.
39. Khan S, Lichtman SN, Reyes J, et al. Ulcerative colitis after liver transplant and immunosuppression. J Pediatr Gastroenterol Nutr 1999;28:206-9.
40. Chalasani N, Smallwood G. Idiopathic ulcerative colitis in patients with primary sclerosing cholangitis undergoing orthotopic liver transplantation (OLT). Am J Gastroenterol 1998;93:481-2.
41. Papadakis KA, Matuk R, Abreu M, et al. Crohn's ileitis after liver transplantation from a living-related donor with Crohn's disease. Gut 2004;53:1389-90.
42. Harms B, Bremner AR, Mulligan J, et al. Crohn's disease post-cardiac transplantation presenting with severe growth failure and delayed onset of puberty. Pediatr Allergy Immunol 2004;15:186-9.