Cytochrome P450 1B1 expression in rat esophageal tumorigenesis promoted by gastric and duodenal reflux

Molecular Carcinogenesis

Volumn 48, Issue 2, 2009, Pages 110-117

  Devlin, Andrea H ^a   McIlroy, Marie ^a   McKeen, Hayley D ^b   Bonde, Pramode ^c   Menezes, A A Carlos ^b   Swarbrick, Christine J ^c   Robson, Tracy ^b   Hirst, David G ^b   Campbell, F Charles ^b   McGuigan, James A ^c   McKeown, Stephanie R ^a  

^a UNIVERSITY OF ULSTER   (United Kingdom)

^b QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^c ROYAL VICTORIA HOSPITAL   (United Kingdom)

Author keywords

CYP1B1; Esophagus; Immunohistochemistry; Rodent; Tumorigenesis

Indexed keywords

CARCINOGEN; CYTOCHROME P450 1B1; FLUORESCEIN; ISOPROPAMIDE IODIDE; MESSENGER RNA; TOBACCO SMOKE; CYTOCHROME P 450 CYP1B1; CYTOCHROME P-450 CYP1B1; UNSPECIFIC MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BARRETT ESOPHAGUS; CARCINOGENESIS; CARCINOMA IN SITU; CELL HYPERPLASIA; CONTROLLED STUDY; DUODENOGASTRIC REFLUX; DYSPLASIA; ESOPHAGUS CANCER; ESOPHAGUS MUCOSA; ESOPHAGUS MUSCLE; FEMALE; FOOD; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LAMINA PROPRIA; MALE; MUSCULARIS MUCOSA; NEWBORN; NONHUMAN; PRECANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RISK FACTOR; SPRAGUE DAWLEY RAT; SQUAMOUS CELL CARCINOMA; SQUAMOUS EPITHELIUM; SUBMUCOSA; ANIMAL; ANTIBODY SPECIFICITY; ENZYMOLOGY; ESOPHAGUS TUMOR; GASTROESOPHAGEAL REFLUX; GENETICS; IMMUNOLOGY; MOUSE; MOUSE MUTANT; WESTERN BLOTTING;

ANIMALIA; NICOTIANA TABACUM; RATTUS; RODENTIA;

ANIMALS; ANTIBODY SPECIFICITY; ARYL HYDROCARBON HYDROXYLASES; BLOTTING, WESTERN; DUODENOGASTRIC REFLUX; ESOPHAGEAL NEOPLASMS; FEMALE; GASTROESOPHAGEAL REFLUX; IMMUNOHISTOCHEMISTRY; MICE; MICE, KNOCKOUT; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

EID: 59849105166     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20459     Document Type: Article

References (39)

1. Vaughan TL, Davis S, Kristal A, Thomas DB. Obesity, alcohol, and tobacco as risk factors for cancers of the esophagus and gastric cardia: Adenocarcinoma versus squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev 1995;4:85-92.
2. Alexandrou A, Davis PA, Law S, Whooley BP, Murthy SC, Wong J. Esophageal cancer in patients with a history of distal gastrectomy. Arch Surg 2002;137:1238-1242.
3. Jankowski J, Henderson K, Viaene A, Baert J, Long LQ. Morphological analysis of gastro-esophageal diseases by molecular cell techniques. Microsc Res Tech 1995;31:184-192.
4. Sutter TR, Tang YM, Hayes CL, et al. Complete cDNA sequence of a human dioxin-inducible mRNA identifies a new gene subfamily of cytochrome P450 that maps to chromosome 2. J Biol Chem 1994;269:13092-13099.
5. ChoudharyD, Jansson I, Schenkman JB, Sarfarazi M, StoilovI. Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues. Arch Biochem Biophys 2003;414:91-100.
6. Choudhary D,Jansson I, StoilovI, Sarfarazi M, Schenkman JB. Expression patterns of mouse and human CYP orthologs (families 1-4) during development and in different adult tissues. Arch Biochem Biophys 2005;436:50-61.
7. Murray GI, Taylor MC, McFadyen MC, et al. Tumor-specific expression of cytochrome P450 CYP1B1. Cancer Res 1997;57:3026-3031.
8. Savas U, Bhattacharyya KK, Christou M, Alexander DL, Jefcoate CR. Mouse cytochrome P-450EF, representative of a new 1B subfamily of cytochrome P-450s. J Biol Chem 1994; 269:14905-14911.
9. Bhattacharyya KK, Brake PB, Eltom SE, Otto SA, Jefcoate CR. Identification of a rat adrenal cytochrome P450 active in polycyclic aromatic hydrocarbon metabolism as rat CYP1B1. J Biol Chem 1995;270:11595-115602.
10. Maecker B, Sherr DH, Vonderheide RH, et al. The shared tumor associated antigen cytochrome P450 1B1 is recognised by specific cytotoxic T cells. Blood 2003;102:3287-3294.
11. McFadyen MC, Cruickshank ME, Miller ID, et al. Cytochrome P450 CYP1B1 over-expression in primary and metastatic ovarian cancer. Br J Cancer 2001;85:242-246.
12. McFadyen MC, Breeman S, Payne S, et al. Immunohisto-chemical localization of cytochrome P450 CYP1B1 in breast cancer with monoclonal antibodies specific for CYP1B1. J Histochem Cytochem 1999;47:1457-1464.
13. Stoilov I, Akarsu AN, Sarfarazi M. Identification of three different truncating mutations in cytochrome P4501B1 (CYP1B1) as the principal cause of primary congenital glaucoma (buphthalmos) in families linked to the GLC3A locus on chromosome 2p21. Hum Mol Genet 1997;6:641-647.
14. Buters JT, Doehmer J, Gonzalez FJ. Cytochrome P450-null mice. Drug Metab Rev 1999;31:437-447.
15. Gould DB, Simin WM. Anterior segment dysgenesis and the developmental glaucomas are complex traits. Hum Mol Genet 2002;11:1185-11893.
16. Ma X, Idle JR, Krausz KW, Gonzalez FJ. Metabolism of
17. melatonin by human cytochromes P450. Drug Metab Dispos 2005;33:489-494.
18. Choudhary D, Jansson I, Stoilov I, Sarfarazi M, Schenkman JB. Metabolism of retiniods and arachidonic acid by human and mouse cytochrome P450 1B1. Drug Metab Dispos 2004;32:840-847.
19. Rahman M, Hayes Sutter C, Emmert GL, Sutter TR. Regio-selective 2-hydroxylation of 17 β-estradiol by rat cytochrome P4501B1. Toxixol Appl Pharmacol 2006;216:469-478.
20. Hayes CL, Spink DC, Spink BC, Cao JQ, Walker NJ, Sutter TR. 17beta-estradiol hydroxylation catalyzed by human cytochrome P4501B1. Proc Nat Acad Sci USA 1996;93:9776-9781.
21. Buters JT, Sakai S, Richter T, et al. Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anth-racene-induced lymphomas. Proc Natl Acad Sci USA 1999; 96:1977-1982.
22. Buters J, Quintanilla-Martinez L, Schober W, et al. CYP1B1 determines susceptibility to low doses of 7, 12-dimethlyben-za[a]anthracene-induced ovarian tumors in mice: Correlation of CYP1B1-mediated DNA adducts with carcinogenicity. Carcinogenesis 2003;24:327-334.
23. Wen X, Walle T. Cytochrome P450 1B1, a novel chemo-preventive target for benzo[a]pyrene-initiated human esophageal cancer. Cancer Lett 2007;246:109-114.
24. Crespi CL, Penman BW, Steimel DT, Smith T, Yang CS, Sutter TR. Development of a human lymphoblastoid cell line constitutively expressing human CYP1B1 cDNA: Substrate specificity with model substrates and promutagens. Mutagenesis 1997;12:83-89.
25. Shimada T, Hayes CL, Yamazaki H, et al. Activation of chemically diverse procarcinogens by human cytochrome P450 1B1. Cancer Res 1996;56:2979-2984.
26. Hanna IH, Dawling S, Roodi N, Guengerich FP, Parl FF. Cytochrome P450 1B1 (CYP1B1) pharmacogenetics: Association of polymorphisms with functional differences in estrogen hydroxylation activity. Cancer Res 2000;60:3440-3444.
27. Tang YM, Green BL, Chen GF, et al. Human CYP1B1 Leu432VAl gene polymorphism; ethnic distribution in African-Americans, Caucasians and Chinese: Oestradiol hydroxylase activity; and distribution in prostate cancer cases and controls. Pharmacogenetics 2000;10:761-766.
28. ShimadaT, WatanabeJ, Kawajiri K,etal. Catalytic properties of polymorphic human cytochrome P450 1B1 variants. Carcinogenesis 1999;20:1607-1613.
29. Tanaka Y, Sasaki M, Kaneuchi M, Shiina H, Igawa M, Dahiya R. Polymorphisms of the CYP1B1 gene have higher risk for prostate cancer. Biochem Biophys Res Commun 2002;296:820-826.
30. Sasaki M, Tanaka Y, Okino ST, et al. Polymorphisms of the CYP1B1 gene as risk factors for human renal cell carcinoma. Clin Cancer Res 2004;10:2015-20019.
31. Sasaki M, Tanaka Y, Kaneuchi M, Sakuragi N, Dahiya R. CYP1B1 gene polymorphisms have higher risk for endometrial cancer, and positive correlations with estrogen receptor a and estrogen receptor β expressions. Cancer Res 2003;63:3913-3918.
32. McGrath M, Hankinson SE, Arbeitman L, et al. Cytochrome P450 1B1 and catechol-O-methyltransferase polymorphisms and endometrial cancer susceptibility. Carcinogenesis 2004;25:559-565.
33. Carnell DM, Smith RE, Daley FM, et al. Target validation of cytochrome P450 CYP1B1 in prostate carcinoma with protein expression in associated hyperplastic and premalignant tissue. Int J Radiat Oncol Biol Phys 2004;58:500-509.
34. Hoang TTV, Burke MD, Butler PC, Seaton A, Stanley LA. Cytochrome P450 1B1 (CYP1B1) expression in human cervical intraepithelial neoplasia. Br J Cancer 2001;85:78.
35. Dvorak K, Chavarria M, Payne CM, et al. Activation of the interleukin-6/STAT3 antiapoptotic pathway in esophageal cells by bile acids and low pH: Relevance to Barrett's Esophagus. Clin Cancer Res 2007;13:5305-5313.
36. Burnat G, Rau T, Elshimi E, Hahn EG, Konturek PC. Bile acids induce overexpression of homeobox gene CDX-2 and vascular endothelial growth factor(VEGF)in human Barrett's esophageal mucosa and adenocarcinoma cell line. Scand J Gastroenterol 2007;42:1460-1465.
37. Bani-Hami K, Martin IG, Hardie LJ, et al. Prospective studyof cyclin D1 overexpression in Barrett's esophagus: Association with increased risk of adenocarcinoma. J Natl Cancer Inst 2000;92:1316-1321.
38. Malaplate-Armand C, Ferrari L, Masson C, Siest G, Batt AM. Astroglial CYP1B1 up-regulation in inflammatory/oxidative toxic conditions: IL-1 β effect and protection by N-acetylcysteine. Toxicol Lett 2003;138:243-251.
39. Coussens L, Werb Z. Inflammation and cancer. Nature 2002;420:860-867.