Diacerein mutual prodrug for osteoarthritis: Synthesis, in vitro kinetic studies and preliminary pharmacological screening

Journal of Drug Delivery Science and Technology

Volumn 19, Issue 1, 2009, Pages 25-29

  Dhaneshwar, Suneela S ^a   Patil, D ^a   Mengi, S ^b   Mulay, G ^b   Lahane, J ^b  

^a BHARATI VIDYAPEETH DEEMED UNIVERSITY   (India)

^b SNDT WOMEN S UNIVERSITY   (India)

Author keywords

D glucosamine; Diacerein; Mutual prodrug; Osteoarthritis

Indexed keywords

ALKALINE PHOSPHATASE; DIACEREIN MUTUAL PRODRUG; DIACETYLRHEIN; GLUCOSAMINE; GLYCOSAMINOGLYCAN; IODOACETIC ACID; PRODRUG; UNCLASSIFIED DRUG;

ADJUVANT ARTHRITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; COLD STRESS; CONTROLLED STUDY; DERIVATIZATION; DISEASE COURSE; DRUG CONJUGATION; DRUG EFFICACY; DRUG HALF LIFE; DRUG HYDROLYSIS; DRUG INDUCED DISEASE; DRUG MECHANISM; DRUG RELEASE; DRUG SCREENING; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME BLOOD LEVEL; FEMALE; HYDROPHILICITY; IN VITRO STUDY; KNEE OSTEOARTHRITIS; LINKAGE ANALYSIS; LOCOMOTION; MALE; NONHUMAN; OSTEOARTHRITIS; PH; RAT; STOMACH; STOMACH IRRITATION;

EID: 59849092367     PISSN: 17732247     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1773-2247(09)50003-2     Document Type: Article

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