-
1
-
-
0027267315
-
Flavonoids from Koelreuteria henryi and other sources as protein-tyrosine kinase inhibitors
-
Abou-Shoer M., Ma G.E., Li X.H., Koonchanok N.M., Geahlen R.L., and Chang C.J. Flavonoids from Koelreuteria henryi and other sources as protein-tyrosine kinase inhibitors. J Nat Prod 56 (1993) 967-969
-
(1993)
J Nat Prod
, vol.56
, pp. 967-969
-
-
Abou-Shoer, M.1
Ma, G.E.2
Li, X.H.3
Koonchanok, N.M.4
Geahlen, R.L.5
Chang, C.J.6
-
2
-
-
0030842112
-
Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: a comparison with tyrosine kinase and protein kinase C inhibition
-
Agullo G., Gamet-Payrastre L., Manenti S., Viala C., Remesy C., Chap H., et al. Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: a comparison with tyrosine kinase and protein kinase C inhibition. Biochem Pharmacol 53 (1997) 1649-1657
-
(1997)
Biochem Pharmacol
, vol.53
, pp. 1649-1657
-
-
Agullo, G.1
Gamet-Payrastre, L.2
Manenti, S.3
Viala, C.4
Remesy, C.5
Chap, H.6
-
3
-
-
52949093091
-
Role of extracellular signal-regulated kinase signal transduction pathway in anxiety
-
Ailing F., Fan L., Li S., and Manji S. Role of extracellular signal-regulated kinase signal transduction pathway in anxiety. J Psychiatr Res (2008)
-
(2008)
J Psychiatr Res
-
-
Ailing, F.1
Fan, L.2
Li, S.3
Manji, S.4
-
4
-
-
0034629007
-
Learning-associated activation of nuclear MAPK, CREB and Elk-1, along with Fos production, in the rat hippocampus after a one-trial avoidance learning: abolition by NMDA receptor blockade
-
Cammarota M., Bevilaqua L.R., Ardenghi P., Paratcha G., Levi de Stein M., Izquierdo I., et al. Learning-associated activation of nuclear MAPK, CREB and Elk-1, along with Fos production, in the rat hippocampus after a one-trial avoidance learning: abolition by NMDA receptor blockade. Brain Res Mol Brain Res 76 (2000) 36-46
-
(2000)
Brain Res Mol Brain Res
, vol.76
, pp. 36-46
-
-
Cammarota, M.1
Bevilaqua, L.R.2
Ardenghi, P.3
Paratcha, G.4
Levi de Stein, M.5
Izquierdo, I.6
-
5
-
-
0035857455
-
Calcium/calmodulin-dependent protein kinase II inhibitor protein: localization of isoforms in rat brain
-
Chang B.H., Mukherji S., and Soderling T.R. Calcium/calmodulin-dependent protein kinase II inhibitor protein: localization of isoforms in rat brain. Neuroscience 102 (2001) 767-777
-
(2001)
Neuroscience
, vol.102
, pp. 767-777
-
-
Chang, B.H.1
Mukherji, S.2
Soderling, T.R.3
-
6
-
-
0035461363
-
Mechanisms of inhibition of the Ras-MAP kinase signaling pathway in 30.7b Ras 12 cells by tea polyphenols (-)-epigallocatechin-3-gallate and theaflavin-3,3'-digallate
-
Chung J.Y., Park J.O., Phyu H., Dong Z., and Yang C.S. Mechanisms of inhibition of the Ras-MAP kinase signaling pathway in 30.7b Ras 12 cells by tea polyphenols (-)-epigallocatechin-3-gallate and theaflavin-3,3'-digallate. Faseb J 15 (2001) 2022-2024
-
(2001)
Faseb J
, vol.15
, pp. 2022-2024
-
-
Chung, J.Y.1
Park, J.O.2
Phyu, H.3
Dong, Z.4
Yang, C.S.5
-
7
-
-
23744455203
-
Valerian extract and valerenic acid are partial agonists of the 5-HT5a receptor in vitro
-
Dietz B.M., Mahady G.B., Pauli G.F., and Farnsworth N.R. Valerian extract and valerenic acid are partial agonists of the 5-HT5a receptor in vitro. Brain Res Mol Brain Res 138 (2005) 191-197
-
(2005)
Brain Res Mol Brain Res
, vol.138
, pp. 191-197
-
-
Dietz, B.M.1
Mahady, G.B.2
Pauli, G.F.3
Farnsworth, N.R.4
-
8
-
-
0141744853
-
Brain region-specific mechanisms for acute morphine-induced mitogen-activated protein kinase modulation and distinct patterns of activation during analgesic tolerance and locomotor sensitization
-
Eitan S., Bryant C.D., Saliminejad N., Yang Y.C., Vojdani E., Keith Jr. D., et al. Brain region-specific mechanisms for acute morphine-induced mitogen-activated protein kinase modulation and distinct patterns of activation during analgesic tolerance and locomotor sensitization. J Neurosci 23 (2003) 8360-8369
-
(2003)
J Neurosci
, vol.23
, pp. 8360-8369
-
-
Eitan, S.1
Bryant, C.D.2
Saliminejad, N.3
Yang, Y.C.4
Vojdani, E.5
Keith Jr., D.6
-
9
-
-
17444424615
-
Synergistic interaction between hesperidin, a natural flavonoid, and diazepam
-
Fernandez S.P., Wasowski C., Paladini A.C., and Marder M. Synergistic interaction between hesperidin, a natural flavonoid, and diazepam. Eur J Pharmacol 512 (2005) 189-198
-
(2005)
Eur J Pharmacol
, vol.512
, pp. 189-198
-
-
Fernandez, S.P.1
Wasowski, C.2
Paladini, A.C.3
Marder, M.4
-
10
-
-
33746402990
-
Central nervous system depressant action of flavonoid glycosides
-
Fernandez S.P., Wasowski C., Loscalzo L.M., Granger R.E., Johnston G.A., Paladini A.C., et al. Central nervous system depressant action of flavonoid glycosides. Eur J Pharmacol 539 (2006) 168-176
-
(2006)
Eur J Pharmacol
, vol.539
, pp. 168-176
-
-
Fernandez, S.P.1
Wasowski, C.2
Loscalzo, L.M.3
Granger, R.E.4
Johnston, G.A.5
Paladini, A.C.6
-
11
-
-
0022353598
-
The effects of triazolobenzodiazepines in two animal tests of anxiety and in the holeboard
-
File S.E., and Pellow S. The effects of triazolobenzodiazepines in two animal tests of anxiety and in the holeboard. Br J Pharmacol 86 (1985) 729-735
-
(1985)
Br J Pharmacol
, vol.86
, pp. 729-735
-
-
File, S.E.1
Pellow, S.2
-
12
-
-
0030827438
-
Opioid effects on mitogen-activated protein kinase signaling cascades
-
Gutstein H.B., Rubie E.A., Mansour A., Akil H., and Woodgett J.R. Opioid effects on mitogen-activated protein kinase signaling cascades. Anesthesiology 87 (1997) 1118-1126
-
(1997)
Anesthesiology
, vol.87
, pp. 1118-1126
-
-
Gutstein, H.B.1
Rubie, E.A.2
Mansour, A.3
Akil, H.4
Woodgett, J.R.5
-
13
-
-
0023897154
-
Differential effects of flavonoids as inhibitors of tyrosine protein kinases and serine/threonine protein kinases
-
Hagiwara M., Inoue S., Tanaka T., Nunoki K., Ito M., and Hidaka H. Differential effects of flavonoids as inhibitors of tyrosine protein kinases and serine/threonine protein kinases. Biochem Pharmacol 37 (1988) 2987-2992
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 2987-2992
-
-
Hagiwara, M.1
Inoue, S.2
Tanaka, T.3
Nunoki, K.4
Ito, M.5
Hidaka, H.6
-
14
-
-
0033063823
-
The scientific basis for the reputed activity of Valerian
-
Houghton P.J. The scientific basis for the reputed activity of Valerian. J Pharm Pharmacol 51 (1999) 505-512
-
(1999)
J Pharm Pharmacol
, vol.51
, pp. 505-512
-
-
Houghton, P.J.1
-
15
-
-
80051842687
-
Neuroprotective effects of the citrus flavanones against H2O2-induced cytotoxicity in PC12 cells
-
Hwang S.L., and Yen G.C. Neuroprotective effects of the citrus flavanones against H2O2-induced cytotoxicity in PC12 cells. J Agric Food Chem 56 (2008) 859-864
-
(2008)
J Agric Food Chem
, vol.56
, pp. 859-864
-
-
Hwang, S.L.1
Yen, G.C.2
-
16
-
-
0037031563
-
Role of GABA(A) receptors in the ethanol-mediated inhibition of extracellular signal-regulated kinase
-
Kalluri H.S., and Ticku M.K. Role of GABA(A) receptors in the ethanol-mediated inhibition of extracellular signal-regulated kinase. Eur J Pharmacol 451 (2002) 51-54
-
(2002)
Eur J Pharmacol
, vol.451
, pp. 51-54
-
-
Kalluri, H.S.1
Ticku, M.K.2
-
17
-
-
0037192577
-
Ethanol-mediated inhibition of mitogen-activated protein kinase phosphorylation in mouse brain
-
Kalluri H.S., and Ticku M.K. Ethanol-mediated inhibition of mitogen-activated protein kinase phosphorylation in mouse brain. Eur J Pharmacol 439 (2002) 53-58
-
(2002)
Eur J Pharmacol
, vol.439
, pp. 53-58
-
-
Kalluri, H.S.1
Ticku, M.K.2
-
18
-
-
33645094927
-
Targeting multiple signaling pathways by green tea polyphenol (-)-epigallocatechin-3-gallate
-
Khan N., Afaq F., Saleem M., Ahmad N., and Mukhtar H. Targeting multiple signaling pathways by green tea polyphenol (-)-epigallocatechin-3-gallate. Cancer Res 66 (2006) 2500-2505
-
(2006)
Cancer Res
, vol.66
, pp. 2500-2505
-
-
Khan, N.1
Afaq, F.2
Saleem, M.3
Ahmad, N.4
Mukhtar, H.5
-
19
-
-
0032862903
-
Quercetin inhibits inducible ICAM-1 expression in human endothelial cells through the JNK pathway
-
Kobuchi H., Roy S., Sen C.K., Nguyen H.G., and Packer L. Quercetin inhibits inducible ICAM-1 expression in human endothelial cells through the JNK pathway. Am J Physiol 277 (1999) C403-411
-
(1999)
Am J Physiol
, vol.277
-
-
Kobuchi, H.1
Roy, S.2
Sen, C.K.3
Nguyen, H.G.4
Packer, L.5
-
20
-
-
38349195051
-
Opioid receptors are involved in the sedative and antinociceptive effects of hesperidin as well as in its potentiation with benzodiazepines
-
Loscalzo L.M., Wasowski C., Paladini A.C., and Marder M. Opioid receptors are involved in the sedative and antinociceptive effects of hesperidin as well as in its potentiation with benzodiazepines. Eur J Pharmacol 580 (2008) 306-313
-
(2008)
Eur J Pharmacol
, vol.580
, pp. 306-313
-
-
Loscalzo, L.M.1
Wasowski, C.2
Paladini, A.C.3
Marder, M.4
-
21
-
-
0041696943
-
6-methylapigenin and hesperidin: new valeriana flavonoids with activity on the CNS
-
Marder M., Viola H., Wasowski C., Fernandez S., Medina J.H., and Paladini A.C. 6-methylapigenin and hesperidin: new valeriana flavonoids with activity on the CNS. Pharmacol Biochem Behav 75 (2003) 537-545
-
(2003)
Pharmacol Biochem Behav
, vol.75
, pp. 537-545
-
-
Marder, M.1
Viola, H.2
Wasowski, C.3
Fernandez, S.4
Medina, J.H.5
Paladini, A.C.6
-
22
-
-
0024839984
-
Benzodiazepine-like molecules as well as other ligands from the brain for the brain benzodiazepine receptor are relatively common constituents of plants
-
Medina J.H., Pena C., Levi de Stein M., Wolfman C., and Paladini A. Benzodiazepine-like molecules as well as other ligands from the brain for the brain benzodiazepine receptor are relatively common constituents of plants. Biochem Biophys Res Commun 165 (1998) 547-555
-
(1998)
Biochem Biophys Res Commun
, vol.165
, pp. 547-555
-
-
Medina, J.H.1
Pena, C.2
Levi de Stein, M.3
Wolfman, C.4
Paladini, A.5
-
23
-
-
0041346211
-
Rap1 couples cAMP signaling to a distinct pool of p42/44MAPK regulating excitability, synaptic plasticity, learning, and memory
-
Morozov A., Muzzio I.A., Bourtchouladze R., Van-Strien N., Lapidus K., Yin D., et al. Rap1 couples cAMP signaling to a distinct pool of p42/44MAPK regulating excitability, synaptic plasticity, learning, and memory. Neuron 39 (2003) 309-325
-
(2003)
Neuron
, vol.39
, pp. 309-325
-
-
Morozov, A.1
Muzzio, I.A.2
Bourtchouladze, R.3
Van-Strien, N.4
Lapidus, K.5
Yin, D.6
-
24
-
-
0346687606
-
Inhibition of the vascular-endothelial growth factor-induced intracellular signaling and mitogenesis of human endothelial cells by epigallocatechin-3 gallate
-
Neuhaus T., Pabst S., Stier S., Weber A.A., Schror K., Sachinidis A., et al. Inhibition of the vascular-endothelial growth factor-induced intracellular signaling and mitogenesis of human endothelial cells by epigallocatechin-3 gallate. Eur J Pharmacol 483 (2004) 223-227
-
(2004)
Eur J Pharmacol
, vol.483
, pp. 223-227
-
-
Neuhaus, T.1
Pabst, S.2
Stier, S.3
Weber, A.A.4
Schror, K.5
Sachinidis, A.6
-
25
-
-
43549110006
-
Neuroprotective effects of hesperetin in mouse primary neurones are independent of CREB activation
-
Rainey-Smith S., Schroetke L.W., Bahia P., Fahmi A., Skilton R., Spencer J.P., et al. Neuroprotective effects of hesperetin in mouse primary neurones are independent of CREB activation. Neurosci Lett 438 (2008) 29-33
-
(2008)
Neurosci Lett
, vol.438
, pp. 29-33
-
-
Rainey-Smith, S.1
Schroetke, L.W.2
Bahia, P.3
Fahmi, A.4
Skilton, R.5
Spencer, J.P.6
-
27
-
-
1842424851
-
Epigallocatechin-3-gallate inhibits epidermal growth factor receptor signaling pathway. Evidence for direct inhibition of ERK1/2 and AKT kinases
-
Sah J.F., Balasubramanian S., Eckert R.L., and Rorke E.A. Epigallocatechin-3-gallate inhibits epidermal growth factor receptor signaling pathway. Evidence for direct inhibition of ERK1/2 and AKT kinases. J Biol Chem 279 (2004) 12755-12762
-
(2004)
J Biol Chem
, vol.279
, pp. 12755-12762
-
-
Sah, J.F.1
Balasubramanian, S.2
Eckert, R.L.3
Rorke, E.A.4
-
28
-
-
0036753143
-
MAPK signaling in neurodegeneration: influences of flavonoids and of nitric oxide
-
Schroeter H., Boyd C., Spencer J.P., Williams R.J., Cadenas E., and Rice-Evans C. MAPK signaling in neurodegeneration: influences of flavonoids and of nitric oxide. Neurobiol Aging 23 (2002) 861-880
-
(2002)
Neurobiol Aging
, vol.23
, pp. 861-880
-
-
Schroeter, H.1
Boyd, C.2
Spencer, J.P.3
Williams, R.J.4
Cadenas, E.5
Rice-Evans, C.6
-
29
-
-
0031926703
-
Opioid withdrawal activates MAP kinase in locus coeruleus neurons in morphine-dependent rats in vivo
-
Schulz S., and Hollt V. Opioid withdrawal activates MAP kinase in locus coeruleus neurons in morphine-dependent rats in vivo. Eur J Neurosci 10 (1998) 1196-1201
-
(1998)
Eur J Neurosci
, vol.10
, pp. 1196-1201
-
-
Schulz, S.1
Hollt, V.2
-
30
-
-
41849125317
-
Prediction of intestinal absorption and metabolism of pharmacologically active flavones and flavanones
-
Serra H., Mendes T., Bronze M.R., and Simplicio A.L. Prediction of intestinal absorption and metabolism of pharmacologically active flavones and flavanones. Bioorg Med Chem 16 (2008) 4009-4018
-
(2008)
Bioorg Med Chem
, vol.16
, pp. 4009-4018
-
-
Serra, H.1
Mendes, T.2
Bronze, M.R.3
Simplicio, A.L.4
-
31
-
-
0041816456
-
Modulation of pro-survival Akt/protein kinase B and ERK1/2 signaling cascades by quercetin and its in vivo metabolites underlie their action on neuronal viability
-
Spencer J.P., Rice-Evans C., and Williams R.J. Modulation of pro-survival Akt/protein kinase B and ERK1/2 signaling cascades by quercetin and its in vivo metabolites underlie their action on neuronal viability. J Biol Chem 278 (2003) 34783-34793
-
(2003)
J Biol Chem
, vol.278
, pp. 34783-34793
-
-
Spencer, J.P.1
Rice-Evans, C.2
Williams, R.J.3
-
32
-
-
0035166616
-
The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory
-
Sweatt J.D. The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory. J Neurochem 76 (2001) 1-10
-
(2001)
J Neurochem
, vol.76
, pp. 1-10
-
-
Sweatt, J.D.1
-
33
-
-
1342289413
-
MAPK cascade signalling and synaptic plasticity
-
Thomas G.M., and Huganir R.L. MAPK cascade signalling and synaptic plasticity. Nat Rev Neurosci 5 (2004) 173-183
-
(2004)
Nat Rev Neurosci
, vol.5
, pp. 173-183
-
-
Thomas, G.M.1
Huganir, R.L.2
-
34
-
-
1842784821
-
Addictive and non-addictive drugs induce distinct and specific patterns of ERK activation in mouse brain
-
Valjent E., Pages C., Herve D., Girault J.A., and Caboche J. Addictive and non-addictive drugs induce distinct and specific patterns of ERK activation in mouse brain. Eur J Neurosci 19 (2004) 1826-1836
-
(2004)
Eur J Neurosci
, vol.19
, pp. 1826-1836
-
-
Valjent, E.1
Pages, C.2
Herve, D.3
Girault, J.A.4
Caboche, J.5
-
35
-
-
35448949428
-
Activation of pro-survival Akt and ERK1/2 signalling pathways underlie the anti-apoptotic effects of flavanones in cortical neurons
-
Vauzour D., Vafeiadou K., Rice-Evans C., Williams R.J., and Spencer J.P. Activation of pro-survival Akt and ERK1/2 signalling pathways underlie the anti-apoptotic effects of flavanones in cortical neurons. J Neurochem 103 (2007) 1355-1367
-
(2007)
J Neurochem
, vol.103
, pp. 1355-1367
-
-
Vauzour, D.1
Vafeiadou, K.2
Rice-Evans, C.3
Williams, R.J.4
Spencer, J.P.5
-
36
-
-
33748436204
-
Anxiolytic properties of green tea polyphenol (-)-epigallocatechin gallate (EGCG)
-
Vignes M., Maurice T., Lante F., Nedjar M., Thethi K., Guiramand J., et al. Anxiolytic properties of green tea polyphenol (-)-epigallocatechin gallate (EGCG). Brain Res 1110 (2006) 102-115
-
(2006)
Brain Res
, vol.1110
, pp. 102-115
-
-
Vignes, M.1
Maurice, T.2
Lante, F.3
Nedjar, M.4
Thethi, K.5
Guiramand, J.6
-
37
-
-
0028017688
-
Isolation of pharmacologically active benzodiazepine receptor ligands from Tilia tomentosa (Tiliaceae)
-
Viola H., Wolfman C., Levi de Stein M., Wasowski C., Pena C., Medina J.H., et al. Isolation of pharmacologically active benzodiazepine receptor ligands from Tilia tomentosa (Tiliaceae). J Ethnopharmacol 44 (1994) 47-53
-
(1994)
J Ethnopharmacol
, vol.44
, pp. 47-53
-
-
Viola, H.1
Wolfman, C.2
Levi de Stein, M.3
Wasowski, C.4
Pena, C.5
Medina, J.H.6
-
38
-
-
0029054098
-
Apigenin, a component of Matricaria recutita flowers, is a central benzodiazepine receptors-ligand with anxiolytic effects
-
Viola H., Wasowski C., Levi de Stein M., Wolfman C., Silveira R., Dajas F., et al. Apigenin, a component of Matricaria recutita flowers, is a central benzodiazepine receptors-ligand with anxiolytic effects. Planta Med 61 (1995) 213-216
-
(1995)
Planta Med
, vol.61
, pp. 213-216
-
-
Viola, H.1
Wasowski, C.2
Levi de Stein, M.3
Wolfman, C.4
Silveira, R.5
Dajas, F.6
-
39
-
-
0001995567
-
Sedative and hypnotic properties of Salvia guaranitica St. Hil. and of its active principle, cirsiliol
-
Viola H., Wasowski C., Marder M., Wolfman C., Paladini A., and Medina J.H. Sedative and hypnotic properties of Salvia guaranitica St. Hil. and of its active principle, cirsiliol. Phytomedicine 4 (1997) 45-50
-
(1997)
Phytomedicine
, vol.4
, pp. 45-50
-
-
Viola, H.1
Wasowski, C.2
Marder, M.3
Wolfman, C.4
Paladini, A.5
Medina, J.H.6
-
40
-
-
0036775629
-
Isolation and identification of 6-methylapigenin, a competitive ligand for the brain GABA(A) receptors, from Valeriana wallichii
-
Wasowski C., Marder M., Viola H., Medina J.H., and Paladini A.C. Isolation and identification of 6-methylapigenin, a competitive ligand for the brain GABA(A) receptors, from Valeriana wallichii. Planta Med 68 (2002) 934-936
-
(2002)
Planta Med
, vol.68
, pp. 934-936
-
-
Wasowski, C.1
Marder, M.2
Viola, H.3
Medina, J.H.4
Paladini, A.C.5
-
41
-
-
0027976019
-
Possible anxiolytic effects of chrysin, a central benzodiazepine receptor ligand isolated from Passiflora coerulea
-
Wolfman C., Viola H., Paladini A., Dajas F., and Medina J.H. Possible anxiolytic effects of chrysin, a central benzodiazepine receptor ligand isolated from Passiflora coerulea. Pharmacol Biochem Behav 47 (1994) 1-4
-
(1994)
Pharmacol Biochem Behav
, vol.47
, pp. 1-4
-
-
Wolfman, C.1
Viola, H.2
Paladini, A.3
Dajas, F.4
Medina, J.H.5
-
42
-
-
0037382257
-
Interaction between flavonoids and the blood-brain barrier: in vitro studies
-
Youdim K.A., Dobbie M.S., Kuhnle G., Proteggente A.R., Abbott N.J., and Rice-Evans C. Interaction between flavonoids and the blood-brain barrier: in vitro studies. J Neurochem 85 (2003) 180-192
-
(2003)
J Neurochem
, vol.85
, pp. 180-192
-
-
Youdim, K.A.1
Dobbie, M.S.2
Kuhnle, G.3
Proteggente, A.R.4
Abbott, N.J.5
Rice-Evans, C.6
|