Estradiol and inflammatory markers in older men

Journal of Clinical Endocrinology and Metabolism

Volumn 94, Issue 2, 2009, Pages 518-522

  Maggio, Marcello ^a,f   Ceda, Gian Paolo ^a   Lauretani, Fulvio ^a   Bandinelli, Stefania ^b   Metter, E Jeffrey ^c   Artoni, Andrea ^a   Gatti, Elisa ^a   Ruggiero, Carmelinda ^c   Guralnik, Jack M ^c   Valenti, Giorgio ^a   Ling, Shari M ^c   Basaria, Shehzad ^c,d   Ferrucci, Luigi ^c,e  

^a UNIVERSITY HOSPITAL OF PARMA   (Italy)

^b SANTA MARIA ANNUNZIATA HOSPITAL   (Italy)

^c NATIONAL INSTITUTE ON AGING   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e HARBOR HOSPITAL   (United States)

^f Department of Internal Medicine and Biomedical Sciences   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; ESTRADIOL; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; TESTOSTERONE; TUMOR NECROSIS FACTOR ALPHA;

AGED; ARTICLE; BODY MASS; CHRONIC DISEASE; CONTROLLED STUDY; HUMAN; MAJOR CLINICAL STUDY; MALE; PHYSICAL ACTIVITY; PRIORITY JOURNAL; SMOKING; TESTOSTERONE BLOOD LEVEL;

EID: 59749098312     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2008-0940     Document Type: Article

References (29)

1. Harman SM, Metter EJ, Tobin JD, Pearson J, Blackman MR 2001 Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging. J Clin Endocrinol Metab 86:724-731
2. Morley JE, Kaiser FE, Perry 3rd HM, Patrick P, Morley PM, Stauber PM, Vellas B, Baumgartner RN, Garry PJ 1997 Longitudinal changes in testosterone, luteinizing hormone, and follicle-stimulating hormone in healthy older men. Metabolism 46:410-413
3. Ferrucci L, Corsi A, Lauretani F, Bandinelli S, Bartali B, Taub DD, Guralnik JM, Longo DL 2005 The origins of age-related proinflammatory state. Blood 105:2294-2299
4. Vermeulen A, Kaufman JM, Goemaere S, van Pottelberg I 2002 Estradiol in elderly men. Aging Male 5:98-102
5. van den Beld AW, de Jong FH, Grobbee DE, Pols HA, Lamberts SW 2000 Measures of bioavailable serum testosterone and estradiol and their relationships with muscle strength, bone density, and body composition in elderly men. J Clin Endocrinol Metab 85:3276-3282
6. Ferrini RL, Barrett-Connor E 1998 Sex hormones and age: a cross-sectional study of testosterone and estradiol and their bioavailable fractions in community-dwelling men. Am J Epidemiol 147:750-754
7. Orwoll E, Lambert LC, Marshall LM, Phipps K, Blank J, Barrett-Connor E, Cauley J, Ensrud K, Cummings S 2006 Testosterone and estradiol among older men. J Clin Endocrinol Metab 91:1336-1344
8. Longcope C, Pratt JH, Schneider SH, Fineberg SE 1978 Aromatization of androgens by muscle and adipose tissue in vivo. J Clin Endocrinol Metab 46:146-152
9. Maggio M, Basaria S, Ble A, Lauretani F, Bandinelli S, Ceda GP, Valenti G, Ling SM, Ferrucci L 2006 Correlation between testosterone and the inflammatory marker soluble interleukin-6 receptor in older men. J Clin Endocrinol Metab 91:345-347
10. Maggio M, Cappola AR, Ceda GP, Basaria S, Chia CW, Valenti G, Ferrucci L 2005 The hormonal pathway to frailty in older men. J Endocrinol Invest 28 (11 Suppl Proceedings):15-19
11. Ferrucci L, Harris TB, Guralnik JM, Tracy RP, Corti MC, Cohen HJ, Penninx B, Pahor M, Wallace R, Havlik RJ 1999 Serum IL-6 level and the development of disability in older persons. J Am Geriatr Soc 47:639-646
12. Malkin CJ, Pugh PJ, Jones RD, Kapoor D, Channer KS, Jones TH 2004 The effect of testosterone replacement on endogenous inflammatory cytokines and lipid profiles in hypogonadal men. J Clin Endocrinol Metab 89:3313-3318
13. Nakhai Pour HR, Grobbee DE, Muller M, van der Schouw YT 2007 Association of endogenous sex hormone with C-reactive protein levels in middle-aged and elderly men. Clin Endocrinol (Oxf) 66:394-398
14. Phillips GB, Castelli WP, Abbott RD, McNamara PM 1983 Association of hyperestrogenemia and coronary heart disease in men in the Framingham Cohort. Am J Med 74:863-869
15. Phillips GB, Pinkernell BH, Jing TY 1996 The association of hyperestrogenemia with coronary thrombosis in men. Arterioscler Thromb Vasc Biol 16:1383-1387
16. Barrett-Connor E, Khaw KT 1988 Endogenous sex hormones and cardiovascular disease in men: a prospective population based study. Circulation 78:539-545
17. Tivesten A, Mellstrom D, Jutberger H, Fagerberg B, Lernfelt B, Orwoll E, Karlsson MK, Ljunggren O, Ohlsson C 2007 Low serum testosterone and high serum estradiol associate with lower extremity peripheral arterial disease in elderly men. The MrOS Study in Sweden. J Am Coll Cardiol 50:1070-1076
18. Abbott RD, Launer LJ, Rodriguez BL, Ross GW, Wilson PW, Masaki KH, Strozyk D, Curb JD, Yano K, Popper JS, Petrovitch H 2007 Serum estradiol and risk of stroke in elderly men. Neurology 68:563-568
19. Ferrucci L, Bandinelli S, Benvenuti E, Di Iorio A, Macchi C, Harris TB, Guralnik JM 2000 Subsystems contributing to the decline in ability to walk: bridging thegap between epidemiology and geriatric practice in the InCHIANTI study. J Am Geriatr Soc 48:1618-1625
20. Valenti G, Denti L, Maggio M, Ceda G, Volpato S, Bandinelli S, Ceresini G, Cappola A, Guralnik JM, Ferrucci L 2004 Effect of DHEA-S on skeletal muscle over the life span: the InCHIANTI study. J Gerontol A Biol Sci Med Sci 59:466-472
21. Folstein MF, Folstein SE, McHugh PR 1975 Mini-mental state. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12:189-198
22. Myers JK, Weissman MM 1980 Use of a self-report symptom scale to detect depression in a community sample. Am J Psychiatry 137:1081-1084
23. Pisani P, Faggiano F, Krogh V, Palli D, Vineis P, Berrino F 1997 Relative validity and reproducibility of a food frequency dietary questionnaire for use in the Italian EPIC centres. Int J Epidemiol 26(Suppl 1):S152-S160
24. Jankowska EW, Medras M, Rogucka EA 2000 Body mass index, waist/hip ratio and androgen-estrogen activity in younger versus older Polish men. Aging Male 3:177-184
25. Khosla S, Atkinson EJ, Dunstan CR, O'Fallon WM 2002 Effect of estrogen versus testosterone on circulating osteoprotegerin and other cytokine levels in normal elderly men. J Clin Endocrinol Metab 87:1550-1554
26. Rochira V, Balestrieri A, Madeo B, Spaggiari A, Carani C 2002 Congenital estrogen deficiency in men: a new syndrome with different phenotypes; clinical and therapeutic implications in men. Mol Cell Endocrinol 193:19-28
27. Laughlin GA, Barrett-Connor E, May S 2006 Sex-specific association of the androgen to oestrogen ratio with adipocytokine levels in older adults: the Rancho Bernardo Study. Clin Endocrinol (Oxf) 65:506-513
28. Purnell JQ, Bland LB, Garzotto M, Lemmon D, Wersinger EM, Ryan CW, Brunzell JD, Beer TM 2006 Effects of transdermal estrogen on levels of lipids, lipase activity, and inflammatory markers in men with prostate cancer. J Lipid Res 47:349-355
29. Maggio M, Guralnik JM, Longo DL, Ferrucci L 2006 Interleukin-6 in aging and chronic disease: a magnificent pathway. J Gerontol A Biol Sci Med Sci 61:575-584