Serum levels and urine detection of Centruroides sculpturatus venom in significantly envenomated patients

Clinical Toxicology

Volumn 47, Issue 1, 2009, Pages 24-28

  Chase, Peter ^a   Boyer Hassen, Leslie ^a   Mcnally, Jude ^a   Vazquez, H L ^b   Theodorou, Andreas A ^a   Walter, Frank Gardner ^c   Alagon, Alejandro ^b  

^a UNIVERSITY OF ARIZONA   (United States)

^b INSTITUTO DE BIOTECNOLOGÍA   (Mexico)

^c UNIVERSITY OF ARIZONA   (United States)

Author keywords

Antivenom; Centruroides sculpturatus; Envenomation; Scorpion

Indexed keywords

IMMUNOGLOBULIN F(AB) FRAGMENT; SCORPION VENOM; VENOM ANTISERUM;

AGED; ARTICLE; BLOOD ANALYSIS; BLOOD LEVEL; CENTRUROIDES SCULPTURATUS; CHILD; CROSS REACTION; DIAGNOSTIC VALUE; ENVENOMATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; PRESCHOOL CHILD; SCORPION; URINALYSIS; URINE LEVEL; WESTERN BLOTTING; ANIMAL; BITES AND STINGS; BLOOD; DRUG DETOXIFICATION; HOSPITALIZATION; INFANT; POLYACRYLAMIDE GEL ELECTROPHORESIS; TIME; URINE;

CENTRUROIDES; CENTRUROIDES SCULPTURATUS; EQUIDAE; SCORPIONES;

AGED, 80 AND OVER; ANIMALS; BITES AND STINGS; BLOTTING, WESTERN; CHILD, PRESCHOOL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; INFANT; METABOLIC DETOXICATION, DRUG; SCORPION VENOMS; SCORPIONS; SEVERITY OF ILLNESS INDEX; TIME FACTORS;

EID: 59649116414     PISSN: 15563650     EISSN: 15569519     Source Type: Journal    
DOI: 10.1080/15563650802039965     Document Type: Article

References (27)

1. Bronstein AC, Spyker DA, Cantilena LR, Green J, Rumack BH, Heard SE. 2006 Annual report of the American Association of Poison Control Centers' National Poison Data System (NPDS). Clin Toxicol 2007; 45:818-917.
2. Likes K, Banner W, Chavez M. Centruroides exilicauda envenomation in Arizona. West J Med 1984; 141(5):634-637.
3. Simard JM, Watt DD, 1990. Venoms and toxins. In: Polis GA, ed. The Biology of Scorpions. Stanford: Stanford University Press; 1990: 414-444.
4. Gwee MCE, Nirthanan S, Khoo HE, Gopalakrishnakone P, Kini RM, Cheah LS. Autonomic effects of some scorpion venoms and toxins. Clin Exp Pharmacol Physiol 2002; 29(9):795-801.
5. Gibly R, Williams M, Walter FG, McNally J, Conroy C, Berg RA. Continuous intravenous midazolam infusion for Centruroides exilicauda scorpion envenomation. Ann Emerg Med 1999; 34(5):620-625.
6. LoVecchio F, Welch S, Klemens J, Curry SC, Thomas R. Incidence of immediate and delayed hypersensitivity to Centruroides antivenom. Ann Emerg Med 1999; 34(5):615-619.
7. Rachesky IJ, Banner W, Dansky J, Tong T. Treatments for Centruroides exilicauda envenomation. Am J Dis Child 1984; 138:1136-1139.
8. Banner W. A scorpion by any other name is still a scorpion. Ann Emerg Med 1999; 34(5):669-670.
9. Dehesa-Davila M, Possani LD. Scorpionism and serotherapy in Mexico. Toxicon 1994; 32(9):1015-1018.
10. Celis A, Gaxiola-Robles R, Sevilla-Godínez E, Orozco Valerio MJ, Armas J. Tendencia de la mortalidad por picaduras de alacrán en México, 1979-2003. Pan Am J Public Health 2007; 21(6): 373-380.
11. +-channels. Eur J Biochem 1999; 264(2):287-300.
12. Possani LD, Merino E, Corona M, Bolivar F, Becerril B. Peptides and genes coding for scorpion toxins that affect ion-channels. Biochimie 2000; 82(9-10):861-868.
13. +-channels. Toxicon 2001; 39(12):1893-1898.
14. Smith, RL. "Scorpions". In: Smith, RL, ed. Venomous Animals of Arizona. 3rd ed. Tucson, Arizona: The Arizona Board of Regents; 1989: 2-3.
15. Dent MAR, Possani LD, Ramirez GA, Fletcher PL. Purification and characterization of two mammalian toxins from the venom of the Mexican scorpion Centruroides noxius Hoffmann. Toxicon 1980; 18(3):343-350.
16. Towbin H, Gordon J. Immunoblotting and dot immunobinding-current status and outlook. J Immunol Methods 1984; 72(2):313-340.
17. Chavez-Olortegui C, Fonseca SCG, Campolina D, Amaral CFS, Diniz CR. ELISA for the detection of toxic antigens in experimental and clinical envenoming by Tityus serrulatus scorpion venom. Toxicon 1994; 32(12):1649-1656.
18. Seifert SA, Boyer LV. Recurrence phenomena after immunoglobulin therapy for snake envenomations: Part 1. Pharmacokinetics and pharmacodynamics of immunoglobulin antivenoms and related antibodies. Ann Emerg Med 2001; 37(2):189-195.
19. Alagon AC, Guzman HS, Martin BM, Ramirez AN, Carbone E, Possani LD. Isolation and characterization of two toxins from the Mexican scorpion Centruroides limpidus limpidus Karsch. Comp Biochem Physiol 1988; 89B(1):153-161.
20. Cevallos MA, Navarro-Duque C, Varela-Julia M, Alagon AC. Molecular mass determination and assay of venom hyaluronidases by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Toxicon 1992; 30(8):925-930.
21. Chávez-Méndez A, Olguín-Pérez L, Olvera-Rodríguez F, Boyer L, Alagón A. Detección y cuantificación de veneno/antiveneno de alacrán Centruroides en plasma humano mediante inmunoensayo. Memories of the XXVI National Congress of the Mexican Society of Biochemistry. Guanajuato, Gto. November 12-17, 2006. (Abstract No. Mi062).
22. Krifi MN, Kharrat H, Zghal K, Abdouli M, Abroug F, Bouchoucha S, Dellagi K, El Ayeb M. Development of an ELISA for the detection of scorpion venoms in sera of humans envenomed by Androctonus australis garsonii and Buthus occitanus tunetanus: correlation with clinical severity of envenoming in Tunisia. Toxicon 1998; 36(6):887-900.
23. Ghalim N, El-Hafny B, Sebti F, Heikel J, Lazar N, Moustanir R, Benslimane A. Scorpion envenomation and serotherapy in Morocco. Am J Trop Med Hyg 2000; 62(2):277-283.
24. de Rezende NA, Dias MB, Campolina D, Chavez-Olortegui C, Amaral CF. Standardization of an enzyme linked immunosorbent assay (ELISA) for detecting circulating toxic venom antigens in patients stung by the scorpion Tityus serrulatus. Rev Inst Med Trop Sao Paulo 1995; 37(1):71-74.
25. Rezende NA, Amaral CFS, Freire-Maia L. Immunotherapy for scorpion envenoming in Brazil. Toxicon 1998; 36(11):1507-1513.
26. Gonzalez C, Cabral J, Reyes S, Uribe J, Escondon C, Alagon A. Development of an immunoenzymatic assay for the quantification of scorpion venom in plasma. Presentation at 4th reunion of experts in envenomation by poisonous animals, 2000, Cuernavaca, Mexico.
27. Ismail M. The scorpion envenoming syndrome. Toxicon 1995; 33(7):825-858.