Immunotherapy for scorpion envenoming in Brazil

Toxicon

Volumn 36, Issue 11, 1998, Pages 1507-1513

  Rezende, N A ^a   Amaral, C F S ^a   Freire Maia, L ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

SCORPION VENOM; VENOM ANTISERUM;

ABSORPTION; ANIMAL EXPERIMENT; ANIMAL MODEL; BLOOD LEVEL; BRAZIL; CONFERENCE PAPER; DISEASE SEVERITY; ENVENOMATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HALF LIFE TIME; HOSPITAL ADMISSION; HUMAN; IMMUNOTHERAPY; NONHUMAN; PAIN; PALLIATIVE THERAPY; PRIORITY JOURNAL; RAT; SCORPION; SUBCUTANEOUS DRUG ADMINISTRATION; TISSUE DISTRIBUTION; VOMITING;

ANIMALS; ARACHNIDISM; BRAZIL; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOTHERAPY; RATS; SCORPION VENOMS; SCORPIONS;

EID: 0031796865     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-0101(98)00141-X     Document Type: Conference Paper

References (13)

1. Boulain J.-C., Ménez A. Neurotoxin-specific immunoglobulins accelerate dissociation of the Neurotoxin-acetylcholine receptor complex. Science. 217:1982;732-733.
2. Campos, J. A., Silva, O. A., Lopez, M. and Freire-Maia, L. (1980) Signs, symptoms and treatment of severe scorpion poisoning in children. In Natural Toxins, eds. D. Eaker and T. Wadstron, pp. 61-68. Pergamon Press, Oxford.
3. Cháves-Olórtegui C., Fonseca S. C. G., Dias M. B., Campolina D., Amaral C. F. S., Diniz C. R. ELISA for the detection of toxic antigens in experimental and clinical envenoming by Tityus serrulatus scorpion venom. Toxicon. 32:1994;1649-1656.
4. Freire-Maia, L. and Campos, J. A. (1989) Pathophysiology and treatment of scorpion poisoning. In Natural Toxins: Characterization, Pharmacology and Therapeutics, eds. C. L. Ownby and G. V. Odell, pp. 139-159. Pergamon Press, Oxford.
5. Freire-Maia L., Campos J. A., Amaral C. F. S. Approaches to the treatment of scorpion envenoming. Toxicon. 32:1994;1009-1014.
6. Freire-Maia, L., Campos, J. A. and Amaral, C. F. S. (1996) Treatment of scorpion envenoming in Brazil. In Envenomings and their Treatments, eds. C. Bon and M. Goyffon, pp. 301-310. Fondation Marcel Merieux, Paris.
7. Gatineau E., Lee C. Y., Fromageot P., Ménez A. Reversal of snake neurotoxin binding to mammalian acetylcholine receptor by specific antiserum. European Journal of Biochemistry. 171:1988;535-539.
8. Ménez, A., Pillet, L., Léonetti, M., Bontems, F. and Maillére (1992) Snake toxins as antigens. In Structure of Antigens, ed. M. H. V. Von Regenmortel, Vol. I, pp. 293-320. CRC Press, Boca Raton, U.S.A.
9. Revelo M. P., Bambirra E. A., Ferreira A. P., Diniz C. R., Cháves-Olórtegui C. Body distribution of Tityus serrulatus scorpion venom in mice and effects of scorpion antivenom. Toxicon. 34:1996;1119-1125.
10. Rezende N. A., Dias M. B., Campolina D., Cháves-Olórtegui C., Diniz C. R., Amaral C. F. S. Efficacy of antivenom therapy for neutralizing circulating venom antigens in patients stung by Tityus serrulatus scorpions. American Journal of Tropical Medicine and Hygiene. 52:1995;277-280.
11. Rezende N. A., Cháves-Olórtegui C., Amaral C. F. S. Is the severity of Tityus serrulatus scorpion envenoming related to plasma venom concentrations? Toxicon. 34:1996;820-823.
12. Santana G. C., Freire A. C. T., Ferreira A. P. L., Cháves-Olórtegui C., Diniz C. R., Freire-Maia L. Pharmacokinetics of Tityus serrulatus scorpion venom determined by enzyme-linked immunosorbent assay in the rat. Toxicon. 34:1996;1063-1066.
13. Silveira J. N., Heneine I. F., Beirão P. S. L. Reversion by polyclonal antibodies of α effects of Tityus serrulatus venom on frog sciatic nerve. Toxicology Letters. 76:1995;187-193.