S100A6 binds p53 and affects its activity

International Journal of Biochemistry and Cell Biology

Volumn 41, Issue 4, 2009, Pages 784-790

  Słomnicki, Łukasz P ^a   Nawrot, Barbara ^b   Leśniak, Wiesława ^a  

^a NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

^b CENTRE OF MOLECULAR AND MACROMOLECULAR STUDIES   (Poland)

Author keywords

Calcyclin; p53; Protein protein interaction; S100A6; siRNA

Indexed keywords

CALCYCLIN; HYDROGEN PEROXIDE; PROTEIN P53; SMALL INTERFERING RNA;

APOPTOSIS; ARTICLE; BIOLOGICAL ACTIVITY; CELL STRAIN HEK293; CONTROLLED STUDY; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; PROTEIN BINDING; PROTEIN CONTENT; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; STRESS;

APOPTOSIS; BINDING SITES; CALCIUM; CELL CYCLE PROTEINS; CELL LINE; CHROMATOGRAPHY, AFFINITY; DNA; ELECTROPHORETIC MOBILITY SHIFT ASSAY; HUMANS; HYDROGEN PEROXIDE; IMMUNOPRECIPITATION; PROTEIN BINDING; RNA, SMALL INTERFERING; S100 PROTEINS; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 59649106781     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2008.08.007     Document Type: Article

References (38)

1. Baudier J., Delphin C., Grunwald D., Khochbin S., and Lawrence J.J. Characterization of the tumor suppressor protein p53 as a protein kinase C substrate and a S100b-binding protein. Proc Natl Acad Sci USA 89 (1992) 11627-11631
2. Fernandez-Fernandez M.R., Veprintsev D.B., and Fersht A.R. Proteins of the S100 family regulate the oligomerization of p53 tumor suppressor. Proc Natl Acad Sci USA 102 (2005) 4735-4740
3. 2(+)-dependent affinity chromatography. Eur J Biochem 195 (1991) 795-800
4. Filipek A., Wojda U., and Leśniak W. Interaction of calcyclin and its cyanogen bromide fragments with annexin II and glyceraldehyde 3-phosphate dehydrogenase. Int J Biochem Cell Biol 27 (1995) 1123-1131
5. Filipek A., and Kuźnicki J. Molecular cloning and expression of a mouse brain cDNA encoding a novel protein target of calcyclin. J Neurochem 70 (1998) 1793-1798
6. Filipek A., Jastrze{ogonek}bska B., Nowotny M., and Kuźnicki J. CacyBP/SIP, a calcyclin and Siah-1-interacting protein, binds EF-hand proteins of the S100 family. J Biol Chem 277 (2002) 28848-28852
7. 2+-dependent binding of calcyclin to muscle tropomyosin. Biochem Biophys Res Commun 220 (1996) 360-365
8. Grigorian M., Andresen S., Tulchinsky E., Kriajevska M., Carlberg C., Kruse C., et al. Tumor suppressor p53 protein is a new target for the metastasis-associated Mts1/S100A4 protein: functional consequences of their interaction. J Biol Chem 276 (2001) 22699-22708
9. Joo J.H., Yoon S.Y., Kim J.H., Paik S.G., Min S.R., Lim J.S., et al. S100A6 (calcyclin) enhances the sensitivity to apoptosis via the upregulation of caspase-3 activity in Hep3B cells. J Cell Biochem 103 (2008) 1183-1197
10. Kim M.S., Li S.L., Bertolami C.N., Cherrick H.M., and Park N.H. State of p53, Rb and DCC tumor suppressor genes in human oral cancer cell lines. Anticancer Res 13 (1993) 1405-1413
11. Komatsu K., Andoh A., Ishiguro S., Suzuki N., Hunai H., Kobune-Fujiwara Y., et al. Increased expression of S100A6 (Calcyclin), a calcium-binding protein of the S100 family, in human colorectal adenocarcinomas. Clin Cancer Res 6 (2000) 172-179
12. Lapi E., Iovino A., Fontemaggi G., Soliera A.R., Iacovelli S., Sacchi A., et al. S100A2 gene is a direct transcriptional target of p53 homologues during keratinocyte differentiation. Oncogene 25 (2006) 3628-3637
13. Lavin M.F., and Gueven N. The complexity of p53 stabilization and activation. Cell Death Differ 13 (2006) 941-950
14. Leśniak W., Szczepańska A., and Kuźnicki J. Calcyclin (S100A6) expression is stimulated by agents evoking oxidative stress via the antioxidant response element. Biochim Biophys Acta 1744 (2005) 29-37
15. Leśniak W., Słomnicki ŁP, and Kuźnicki J. Epigenetic control of the S100A6 (calcyclin) gene expression. J Invest Dermatol 127 (2007) 2307-2314
16. Li Q., Falsey R.R., Gaitonde S., Sotello V., Kislin K., and Martinez J.D. Genetic analysis of p53 nuclear importation. Oncogene 26 (2007) 7885-7893
17. Lin J., Blake M., Tang C., Zimmer D., Rustandi R.R., Weber D.J., et al. Inhibition of p53 transcriptional activity by the S100B calcium-binding protein. J Biol Chem 276 (2001) 35037-35041
18. Lin J., Yang Q., Yan Z., Markowitz J., Wilder P.T., Carrier F., et al. Inhibiting S100B restores p53 levels in primary malignant melanoma cancer cells. J Biol Chem 279 (2004) 34071-34077
19. Mani R.S., McCubbin W.D., and Kay C.M. Calcium-dependent regulation of caldesmon by an 11 kDa smooth muscle calcium-binding protein, caltropin. Biochemistry 31 (1992) 11896-11901
20. Minami H., Tokumitsu H., Mizutani A., Watanabe Y., Watanabe M., and Hidaka H. Specific binding of CAP-50 to calcyclin. FEBS Lett 305 (1992) 217-219
21. Mueller A., Schäfer B.W., Ferrari S., Weibel M., Makek H., Höchli M., et al. The calcium-binding protein S100A2 interacts with p53 and modulates its transcriptional activity. J Biol Chem 280 (2005) 29186-29193
22. Nowotny M., Spiechowicz M., Jastrze{ogonek}bska B., Filipek A., Kitagawa K., and Kuźnicki J. Calcium-regulated interaction of Sgt1 with S100A6 (calcyclin) and other S100 proteins. J Biol Chem 278 (2003) 26923-26928
23. Ohuchida K., Mizumoto K., Ishikawa N., Fujii K., Konomi H., Nagai E., et al. The role of S100A6 in pancreatic cancer development and its clinical implication as a diagnostic marker and therapeutic target. Clin Cancer Res 11 (2005) 7785-7793
24. Orre L.M., Pernemalm M., Lengqvist J., Lewensohn R., and Lehtiö J. Up-regulation, modification, and translocation of S100A6 induced by exposure to ionizing radiation revealed by proteomics profiling. Mol Cell Proteom 6 (2007) 2122-2131
25. Ostermeyer A.G., Runko E., Winkfield B., Ahn B., and Moll U.M. Cytoplasmically sequestered wild-type p53 protein in neuroblastoma is relocated to the nucleus by a C-terminal peptide. Proc Natl Acad Sci USA 93 (1996) 15190-15194
26. Rustandi R.R., Baldisseri D.M., and Weber D.J. Structure of the negative regulatory domain of p53 bound to S100B(ββ). Nat Struct Biol 7 (2000) 570-574
27. Santamaria-Kisiel L., Rintala-Dempsey A.C., and Shaw G.S. Calcium-dependent and -independent interactions of the S100 protein family. Biochem J 396 (2006) 201-214
28. 2+)-signal transduction by S100 proteins. Structure 6 (1998) 223-231
29. Scotto C., Deloulme J.C., Rousseau D., Chambaz E., and Baudier J. Calcium and S100B regulation of p53-dependent cell growth arrest and apoptosis. Mol Cell Biol 18 (1998) 4272-4281
30. Scotto C., Delphin C., Deloulme J.C., and Baudier J. Concerted regulation of wild-type p53 nuclear accumulation and activation by S100B and calcium-dependent protein kinase C. Mol Cell Biol 19 (1999) 7168-7180
31. Spiechowicz M., Żylicz A., Bieganowski P., Kuźnicki J., and Filipek A. Hsp70 is a new target of Sgt1-an interaction modulated by S100A6. Biochem Biophys Res Commun 357 (2007) 1148-1153
32. + binding S100A6 protein in normal, preneoplastic and neoplastic colon mucosa. Eur J Cancer 36 (2000) 1050-1059
33. Tan M., Heizmann C.W., Guan K., Schafer B.W., and Sun Y. Transcriptional activation of the human S100A2 promoter by wild-type p53. FEBS Lett 445 (1999) 265-268
34. Vimalachandran D., Greenhalf W., Thompson C., Lüttges J., Prime W., Campbell F., et al. High nuclear S100A6 (Calcyclin) is significantly associated with poor survival in pancreatic cancer patients. Cancer Res 65 (2005) 3218-3225
35. 2+-dependent manner. Protein Sci 7 (1998) 794-798
36. Wills F.L., McCubbin W.D., and Kay C.M. Smooth muscle calponin-caltropin interaction: effect on biological activity and stability of calponin. Biochemistry 33 (1994) 5562-5569
37. Yamamoto H., Ozaki T., Nakanishi M., Kikuchi H., Yoshida K., Horie H., et al. Oxidative stress induces p53-dependent apoptosis in hepatoblastoma cell through its nuclear translocation. Genes Cells 12 (2007) 461-471
38. Zeng F.Y., Gerke V., and Gabius H.J. Identification of annexin II, annexin VI and glyceraldehyde-3-phosphate dehydrogenase as calcyclin-binding proteins in bovine heart. Int J Biochem 25 (1993) 1019-1027