1-Amido-1-phenyl-3-piperidinylbutanes - CCR5 antagonists for the treatment of HIV. Part 1

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 4, 2009, Pages 1075-1079

  Barber, Christopher G ^a   Blakemore, David C ^a   Chiva, Jean Yves ^a   Eastwood, Rachel L ^a   Middleton, Donald S ^a   Paradowski, Kerry A ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

Antagonist; Antiviral; CCR5; HIV

Indexed keywords

1 AMIDO 1 PHENYL 3 PIPERIDINYLBUTANE; AMIDE; BENZENE DERIVATIVE; CHEMOKINE RECEPTOR CCR5 ANTAGONIST; MARAVIROC; PIPERIDINE DERIVATIVE; POTASSIUM CHANNEL HERG; TROPANE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CELL STRAIN CACO 2; DRUG POTENCY; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IC 50; MICROSOME; NONHUMAN; STEREOSPECIFICITY; STRUCTURE ACTIVITY RELATION; WHOLE CELL;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ANTI-HIV AGENTS; BUTANES; COMBINATORIAL CHEMISTRY TECHNIQUES; ETHER-A-GO-GO POTASSIUM CHANNELS; HIV; HIV INFECTIONS; HUMANS; MOLECULAR STRUCTURE; PIPERIDINES; RECEPTORS, CCR5; STRUCTURE-ACTIVITY RELATIONSHIP; TROPANES;

EID: 59649101606     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.01.009     Document Type: Article

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