Evaluation of sphingolipids in wistar rats treated to prolonged and single oral doses of fumonisin b1

International Journal of Molecular Sciences

Volumn 10, Issue 1, 2009, Pages 50-61

  Direito, Glória M ^a   Almeida, Adriana P ^b   Aquino, Simone ^c   Reis, Tatiana Alves Dos ^d   Pozzi, Claudia Rodrigues ^e   Corrêa, Benedito ^d  

^a FEDERAL RURAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b INSTITUTO ADOLFO LUTZ   (Brazil)

^c INSTITUTO DE PESQUISAS ENERGÉTICAS E NUCLEARES   (Brazil)

^d UNIVERSITY OF SÃO PAULO   (Brazil)

^e INSTITUTO DE ZOOTECNIA   (Brazil)

Author keywords

Biomarkers; Fumonisin B1; Prolonged effect; Single dose; Sphingolipids; Wistar rats

Indexed keywords

FUMONISIN B1; SPHINGANINE; SPHINGOLIPID; SPHINGOSINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EVALUATION; LIPID ANALYSIS; LIPID BLOOD LEVEL; LIPID LIVER LEVEL; LIPOGENESIS; LONG TERM EXPOSURE; MALE; NONHUMAN; RAT; URINARY EXCRETION; URINE LEVEL; WISTAR RAT;

BIOMARKERS; FUMONISIN B1; PROLONGED EFFECT; SINGLE DOSE; SPHINGOLIPIDS; WISTAR RATS;

ADMINISTRATION, ORAL; ANIMALS; FUMONISINS; LIVER; RATS; RATS, WISTAR; SPHINGOSINE;

ANIMALIA; RATTUS NORVEGICUS;

EID: 59649091489     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms10010050     Document Type: Article

References (51)

1. Gelderblom, W.C.A.; Jaskiewicz, K.; Marasas, W.F.O.; Thiel, P.G.; Horak R.M.; Vleggaar, R.; Kriek, N.P.J. Fumonisins - Novel mycotoxins with cancer promotion activity produced by Fusarium moniliforme. Appl. Environ. Microbiol. 1988, 54, 1806-1811.
2. 1 production by Fusarium species other than F. moniliforme in Section Liseola a by some related species. Appl. Environ. Microbiol. 1992, 55, 984-989.
3. 1 isolated from Fusarium moniliforme. Onderstepoort J. Vet. Res. 1988, 55, 197-203.
4. 1. Onderstepoort J. Vet. Res. 1990, 57, 269-275.
5. 1 containing Fusarium moniliforme culture material in weaned piglets. Food Chem. Toxicol. 2003, 41, 1345-1353.
6. 1. Toxicology 2001, 161, 39-51.
7. Ledoux, D.R.; Brown, T.P.; Weibking, T.S.; Rottinghaus, G.E. Fumonisin toxicity in broiler chicks. J. Vet. Diagn. Invest. 1992, 4, 330-333.
8. Tran, S.T.; Tardieu, D.; Auvergne, A.; Bailly, J.D.; Babilé, R.; Durand, S.; Benard, G.; Guerre, P. Serum sphinganine and the sphinganine to sphingosine ratio as a biomarker of dietary fumonisins during chronic exposure in ducks. Chem. Biol. Interact. 2006, 160, 41-50.
9. Rheeder, J.P.; Marasas, W.F.O.; Theil, P.G.; Sydenham, E.W.; Shephard, G.S.; Van Schalkwyk, D.J. Fusarium moniliforme and fumonisins in corn in relation to human esophageal cancer in Transkei. Phytopathology 1992, 82, 353-357.
10. Sydenham, E.W.; Theil, P.G.; Marasas, W.F.O.; Shephard, G.S.; Vanschalkwyk, D.J.; Koch, K.R., Natural occurrence of some Fusarium mycotoxins in corn from low and high esophageal cancer prevalence areas of the Transkei, Southern Africa. J. Agric. Food Chem. 1990, 38, 1900-1903.
11. Marasas, W.F.O. Fumonisins: History, World-wide Occurrence and Impact. Jackson, L.S., de Vries, J.W., Bullerman, L.B., Eds.; Plenum Press: New York, 1996; volume 392, Chapter 1, pp. 1-17.
12. 2 and Fusarin C (Group 2B), Monographs on the Evaluation of Carcinogenic Risks to Humans. IARC: Lyon, 1993; vol. 56, pp. 445.
13. 1 induces disruption of sphingolipid metabolism in Sprague-Dawley rats: A new mechanism of nephrotoxicity. J. Nutr. 1994, 124, 594-603.
14. Riley, R.T.; Wang, E.; Schroeder, J.J.; Smith, E.R.; Plattner, R.D.; Abbas, H.; Yoo, H.S.; Merrill A.H. Jr. Evidence for disruption of sphingolipid metabolism as a contributing factor in the toxicity and carcinogenicity of fumonisins. Nat. Toxins, 1996, 4, 3-15.
15. Riley, R.T.; Voss, K.A.; Norred, W.P.; Sharma, R.P.; Wang, E.; Merrill, A.H., Jr. Fumonisins: Mechanism of mycotoxicity. Revue Méd. Vet. 1998, 149, 617-626.
16. Merrill, A.H., Jr.; Wang, E.; Vales, T.R.; Smith, E.R.; Schroeder, J.J.; Menaldino. D.S.; Alexander, C.; Crane, H.M.; Xia, J.; Liotta, D.C.; Meredith, F.I.; Riley, R.T. Fumonisin Toxicity and Sphingolipid Biosynthesis. Jackson, L.S., de Vires, J.W., Bullerman, L.B., Eds.; Plenum Press: New York, 1996; vol. 392, Chapter 4, pp. 297-306.
17. Turner, P.C.; Nikiema, P.; Wild, C.P. Fumonisin contamination of food progress in development of biomarkers to better assess human health risks. Mutat. Res. 1999, 443, 81-93.
18. Shephard, G.S.; Van Der Westhuizen, L.; Sewram, V. Biomarkers of exposure to fumonisin mycotoxins: A review. Food Addit. Contam. 2007, 24, 1196-1201.
19. Ribar, S.; Mesaric, M.; Bauman, M. High-performance liquid chromatographic determination of sphinganine and sphingosine in serum and urine of subjects from an endemic nephropathy area in Croatia. J. Chromatogr. B. 2001, 754, 511-519.
20. Solfrizzo, M.; Visconti, A.; Avantaggiato, G.; Torres, A.; Chulze, S. In vitro and in vivo studies to assess the effectiveness of cholestiramine as a binding agent for fumonisins. Mycopathologia 2000, 151, 147-153.
21. Spiegel, S.; Milstien, S. Sphingosine-1-phosphate: signaling inside and out. FEBBS Letters, 2000, 476, 55-57.
22. 1 in vervet monkeys. Nat. Toxins, 1995, 3, 145-150.
23. Wang, E.; Ross, F.; Wilson, T.M.; Riley, R.T.; Merrill, A.H., Jr. Increase in serum sphingosine and sphinganine and decrease in complex sphingolipids in ponies given feed containing fumonisins, mycotoxins produced by Fusarium moniliforme. J. Nutr. 1992, 122, 1706-1716.
24. Hussein, H.S.; Brasel, J.M. Toxicity, metabolism and impact of mycotoxin on humans and animals. Toxicology 2001, 167, 101-134.
25. 1 in rats. Mycopathologia 2000, 151, 21-27.
26. 1 in B6C3F mice and Fischer 344 rats. Fund. Appl. Toxicol. 1995, 24, 102-110.
27. 1: a mycotoxin produced by Fusarium moniliforme (=F. verticillioides). Cancer Det. Prev. 2002, 26, 1-9.
28. Riley, R.T.; Voss, K.A. Differential sensitivity of rat kidney and liver to fumonisin toxicity: Organ-specific differences in toxin accumulation and sphingoid base metabolism. Toxicol. Sci. 2006, 92, 335-345.
29. 1.Vet. Hum, Toxicol. 1999, 47, 357-362.
30. Soares, L.M.V.; Rodrigues-Amaya, D. Survey of aflatoxins, ochratoxin A, zearalenone and sterigmatocystin in some Brazilian foods by using multitoxin thin layer chromatographic method. J. Assoc. Off. Anal. Chem. 1989, 72, 22-26.
31. 3 in corn. J. Assoc. Off. Anal. Chem. 1996, 79, 688-696.
32. Riley, R.T.; Wang, E.; Merrill, A.H., Jr. Liquid chromatographic determination of sphinganine and sphingosine: Use of the free sphinganine-to-sphingosine ratio as a biomarker for consumption of fumonisins. AOAC Int. 1994, 77, 533-540.
33. Castegnaro, M.; Garren, L.; Galendo, D.; Gelderblom, W.C.A.; Chelule, P.; Dutton, M.F.; Wild, C.P. Analytical method for the determination of sphinganine and sphingosine in serum as a potential biomarker for fumonisin exposure. J. Chromatogr. B 1998, 720, 15-24.
34. Castegnaro, M.; Garren, L.; Gaucher, I.; Wild, C.P. Development of a new method for the analysis of sphinganine and sphingosine in urine and tissues. Nat. Toxins 1996, 4, 284-290.
35. Shephard, G.S.; van der Westhuizen, L. Liquid chromatographic determination of the sphinganine/sphingosine ratio in serum. J. Chromatogr. B., 1998, 710, 219-222.
36. 3 cause hepato and nephrotoxicity in rats. Mycopathologia, 1998, 141, 45-58.
37. Tolleson, W.H.; Dookey, K.L.; Sheldon, W.G.; Thurman, J.D.; Bucci, T.J.; Howard, P.C. The Mycotoxin Fumonisin Induces Apoptosis in Cultures Human Cells and Livers and Kidneys of Rats. Jackson, L.S., De Vries, J.W., Bullerman, L.B., Eds.; Plenum Press: New York, 1996; Volume 392, Chapter 4, p.237.
38. 1 mice: A 14 day gavage study. Food Chem. Toxicol. 1997, 35, 981-989.
39. 1. Food Addit. Contam. 2001, 18, 850-856.
40. Riley, R.T.; Enongene, E.; Voss, K.A.; Norred, W.P.; Meredith, F.I.; Sharma, R.P.; Spitsbergen, J.; Williams, D.E.; Carlson, D.B.; Merrill, A.H., Jr. Sphingolipid perturbation as mechanism for fumonisin carcinogenesis. Environ. Health Perspect. 2001, 109, 301-308.
41. Merrill, A.H., Jr.; Schmelz, E.M.; Dillehay, D.L.; Spiegel, S.; Shayman, J. A.; Schroeder, J. J.; Rilley, R. T.; Voss, K. A.; Wang, E. Sphingolipids - The enigmatic lipid class; Biochemistry, Physiology and Pathophysiology. Toxicol. Appl. Pharmacol. 1997, 142, 208-225.
42. 1: Characteristics of urinary biomarkers for exposure to fumonisins. J. Nutr. 1999, 129, 214-220.
43. 1. Food Chem. Toxicol. 2000, 38, 793-799.
44. 1 exposure in ducks. Chem. Biol. Interact. 2003, 46, 61-72.
45. 1 in rabbits: Nephrotoxicity and sphingolipid alterations. Nat. Toxins. 1995, 3, 395-403.
46. 1 in rabbits: Nephrotoxicity and sphingolipid alterations. Fundam. Appl. Toxicol. 1997, 40, 120-128.
47. 2 on the sphinganine and sphingosine concentrations in vervet monkeys. Food Chem. Toxicol. 2001, 39, 455-459.
48. 1. Progr. Lipids Res. 2005, 44, 345-356.
49. Cai, Q.; Tang, L.; Wang, J.S. Validation of fumonisin biomarkers in F344 rats. Toxicol. Appl. Pharmacol. 2007, 225, 28-39.
50. Voss, K.A.; Riley, R.T.; Norred, W.P.; Bacon, C.W.; Meredith, F.I.; Howard, P.C.; Plattner, R.D.; Collins. T.F.X.; Hansen, D.K.; Porter, J.K. An overview of rodent toxicities: Liver and kidney effects of fumonisins and Fusarium moniliforme. Environ. Health Perspect. 2001, 109, 259-266.
51. Delongchamp, R.R.; Young, J.F. Tissue sphinganine as a biomarker of fumonisin-induced apoptosis. Food Addit. Contam. 2001, 18, 255-261.