Lymph sacs are not required for the initiation of lymph node formation

Development

Volumn 136, Issue 1, 2009, Pages 29-34

  Vondenhoff, Mark F ^a   van de Pavert, Serge A ^a   Dillard, Miriam E ^b   Greuter, Mascha ^a   Goverse, Gera ^a   Oliver, Guillermo ^b   Mebius, Reina E ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

Lymph nodes; Lymph sacs; Lymphatic endothelial cells; Lymphoid tissue inducer cell; PROX1

Indexed keywords

HOMEODOMAIN PROTEIN; PROSPERO RELATED HOMEOBOX PROTEIN 1; UNCLASSIFIED DRUG; PROSPERO RELATED HOMEOBOX 1 PROTEIN; PROSPERO-RELATED HOMEOBOX 1 PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ANIMAL TISSUE; ARTICLE; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; HEMATOPOIETIC CELL; LYMPH NODE; LYMPHANGIOGENESIS; MOUSE; MOUSE MUTANT; NONHUMAN; PRIORITY JOURNAL; ANIMAL; ANIMAL EMBRYO; C57BL MOUSE; CYTOLOGY; ENDOTHELIUM CELL; HETEROZYGOTE; LYMPH VESSEL; LYMPH VESSEL ENDOTHELIUM; METABOLISM; PRENATAL DEVELOPMENT;

MAMMALIA;

ANIMALS; EMBRYO, MAMMALIAN; ENDOTHELIAL CELLS; ENDOTHELIUM, LYMPHATIC; HETEROZYGOTE; HOMEODOMAIN PROTEINS; LYMPH NODES; LYMPHATIC VESSELS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; TUMOR SUPPRESSOR PROTEINS;

EID: 59649089383     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.028456     Document Type: Article

References (25)

1. Banerji, S., Ni, J., Wang, S. X., Clasper, S., Su, J., Tammi, R., Jones, M. and Jackson, D. G. (1999). LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan. J. Cell Biol. 144, 789-801.
2. Breier, G., Breviario, F., Caveda, L., Berthier, R., Schnürch, H., Gotsch, U., Vestweber, D., Risau, W. and Dejana, E. (1996). Molecular cloning and expression of murine vascular endothelial-cadherin in early stage development of cardiovascular system. Blood 87, 630-641.
3. Breiteneder-Geleff, S., Soleiman, A., Kowalski, H., Horvat, R., Amann, G., Kriehuber, E., Diem, K., Weninger, W., Tschachler, E., Alitalo, K. et al. (1999). Angiosarcomas express mixed endothelial phenotypes of blood and lymphatic capillaries: podoplanin as a specific marker for lymphatic endothelium. Am. J. Pathol. 154, 385-394.
4. Cupedo, T., Vondenhoff, M. F., Heeregrave, E. J., De Weerd, A. E., Jansen, W., Jackson, D. G., Kraal, G. and Mebius, R. E. (2004). Presumptive lymph node organizers are differentially represented in developing mesenteric and peripheral nodes. J. Immunol. 173, 2968-2975.
5. Eberl, G., Marmon, S., Sunshine, M. J., Rennert, P. D., Choi, Y. and Littman, D. R. (2004). An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells. Nat. Immunol. 5, 64-73.
6. Hallmann, R., Mayer, D. N., Berg, E. L., Broermann, R. and Butcher, E. C. (1995). Novel mouse endothelial cell surface marker is suppressed during differentiation of the blood brain barrier. Dev. Dyn. 202, 325-332.
7. Harvey, N. L., Srinivasan, R. S., Dillard, M. E., Johnson, N. C., Witte, M. H., Boyd, K., Sleeman, M. W. and Oliver, G. (2005). Lymphatic vascular defects promoted by Prox1 haploinsufficiency cause adult-onset obesity. Nat. Genet. 37, 1072-1081.
8. Honda, K., Nakano, H., Yoshida, H., Nishikawa, S., Rennert, P., Ikuta, K., Tamechika, M., Yamaguchi, K., Fukumoto, T., Chiba, T. et al. (2001). Molecular basis for hematopoietic/mesenchymal interaction during initiation of Peyer's patch organogenesis. J. Exp. Med. 193, 621-630.
9. Hong, Y. K., Harvey, N., Noh, Y. H., Schacht, V., Hirakawa, S., Detmar, M. and Oliver, G. (2002). Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate. Dev. Dyn. 225, 351-357.
10. Kaipainen, A., Korhonen, J., Mustonen, T., van Hinsbergh, V. W., Fang, G. H., Dumont, D., Breitman, M. and Alitalo, K. (1995). Expression of the fmslike tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development. Proc. Natl. Acad. Sci. USA 92, 3566-3570.
11. Kisanuki, Y. Y., Hammer, R. E., Miyazaki, J., Williams, S. C., Richardson, J. A. and Yanagisawa, M. (2001). Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo. Dev. Biol. 230, 230-242.
12. Kukk, E., Lymboussaki, A., Taira, S., Kaipainen, A., Jeltsch, M., Joukov, V. and Alitalo, K. (1996). VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development. Development 122, 3829-3837.
13. Mebius, R. E. (2003). Organogenesis of lymphoid tissues. Nat. Rev. Immunol. 3, 292-303.
14. Mebius, R. E., Streeter, P. R., Michie, S., Butcher, E. C. and Weissman, I. L. (1996). A developmental switch in lymphocyte homing receptor and endothelial vascular addressin expression regulates lymphocyte homing and permits CD4+ CD3- cells to colonize lymph nodes. Proc. Natl. Acad. Sci. USA 93, 11019-11024.
15. Petrova, T. V., Makinen, T., Makela, T. P., Saarela, J., Virtanen, I., Ferrell, R. E., Finegold, D. N., Kerjaschki, D., Yla-Herttuala, S. and Alitalo, K. (2002). Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor. EMBO J. 21, 4593-4599.
16. Sabin, F. R. (1902). On the origin of the lymphatic system from the veins and the development of the lymph hearts and thoracic duct in the pig. Am. J. Anat. 1, 367-389.
17. Sabin, F. R. (1909). The lymphatic system in human embryos, with a consideration of the morphology of the system as a whole. Am. J. Anat. 9, 43-91.
18. Sato, T. N., Qin, Y., Kozak, C. A. and Audus, K. L. (1993). Tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system. Proc. Natl. Acad. Sci. USA 90, 9355-9358.
19. Srinivasan, R. S., Dillard, M. E., Lagutin, O. V., Lin, F. J., Tsai, S., Tsai, M. J., Samokhvalov, I. M. and Oliver, G. (2007). Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature. Genes Dev. 21, 2422-2432.
20. Sun, Z., Unutmaz, D., Zou, Y. R., Sunshine, M. J., Pierani, A., Brenner-Morton, S., Mebius, R. E. and Littman, D. R. (2000). Requirement for RORgamma in thymocyte survival and lymphoid organ development. Science 288, 2369-2373.
21. Vondenhoff, M. F., Kraal, G. and Mebius, R. E. (2007). Lymphoid organogenesis in brief. Eur. J. Immunol. 37 Suppl. 1, S46-S52.
22. White, A., Carragher, D., Parnell, S., Msaki, A., Perkins, N., Lane, P., Jenkinson, E., Anderson, G. and Caamano, J. H. (2007). Lymphotoxin adependent and -independent signals regulate stromal organizer cell homeostasis during lymph node organogenesis. Blood 110, 1950-1959.
23. Wigle, J. T. and Oliver, G. (1999). Prox1 function is required for the development of the murine lymphatic system. Cell 98, 769-778.
24. Wigle, J. T., Harvey, N., Detmar, M., Lagutina, I., Grosveld, G., Gunn, M. D., Jackson, D. G. and Oliver, G. (2002). An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype. EMBO J. 21, 1505-1513.
25. Yoshida, H., Naito, A., Inoue, J., Satoh, M., Santee-Cooper, S. M., Ware, C. F., Togawa, A., Nishikawa, S. and Nishikawa, S. (2002). Different cytokines induce surface lymphotoxin-alphabeta on IL-7 receptor-alpha cells that differentially engender lymph nodes and Peyer's patches. Immunity 17, 823-833.