A neonatal piglet model of intraventricular hemorrhage and posthemorrhagic ventricular dilation

Journal of Neurosurgery

Volumn 107, Issue 2 SUPPL., 2007, Pages 126-136

  Aquilina, Kristian ^a,b   Hobbs, Catherine ^a   Cherian, Shobha ^a   Tucker, Alexander ^a   Porter, Helen ^a   Whitelaw, Andrew ^c   Thoresen, Marianne ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b FRENCHAY HOSPITAL   (United Kingdom)

^c UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Neonatal hydrocephalus; Neonatal intraventricular hemorrhage; Pediatric neurosurgery; Pig; Ventricular dilation

Indexed keywords

ANIMAL; ARTICLE; BLOOD; BRAIN HEMORRHAGE; BRAIN VENTRICLE; CEREBROSPINAL FLUID; DISEASE MODEL; HEMATOCRIT; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRACRANIAL PRESSURE; LESIONS AND DEFECTS; NEWBORN; PATHOLOGY; PATHOPHYSIOLOGY; PILOT STUDY; SWINE;

ANIMALS; ANIMALS, NEWBORN; BLOOD; CEREBRAL VENTRICLES; CEREBROSPINAL FLUID; DILATATION, PATHOLOGIC; DISEASE MODELS, ANIMAL; HEMATOCRIT; INJECTIONS, INTRAVENTRICULAR; INTRACRANIAL HEMORRHAGES; INTRACRANIAL PRESSURE; PILOT PROJECTS; SWINE;

EID: 59649086716     PISSN: 00223085     EISSN: 19330693     Source Type: Journal    
DOI: 10.3171/PED-07/08/126     Document Type: Article

References (41)

1. Blasberg R, Johnson D, Fenstermacher J: Absorption resistance of cerebrospinal fluid after subarachnoid haemorrhage in the monkey; effects of heparin. Neurosurgery 9:686-691, 1981 (Pubitemid 12196170)
2. Brann BS IV, Qualls C, Wells L, Papile L: Asymmetric growth of the lateral cerebral ventricle in infants with posthemorrhagic ventricular dilatation. J Pediatr 118:108-112, 1991
3. Cherian SS, Love S, Silver IA, Porter HJ, Whitelaw AGL, Thoresen M: Posthemorrhagic ventricular dilation in the neonate: development and characterization of a rat model. J Neuropathol Exp Neurol 62:292-303, 2003 (Pubitemid 36330680)
4. Davies MW, Swaminathan M, Chuang SL, Betheras FR: Reference ranges for the linear dimensions of the intracranial ventricles in preterm neonates. Arch Dis Child Fetal Neonatal Ed 82:F218-F223, 2000 (Pubitemid 30313558)
5. Del Bigio MR: Neuropathological changes caused by hydrocephalus. Acta Neuropathol (Berl) 85:573-585, 1993
6. Dickerson JWT, Dobbing J: Prenatal and postnatal growth and development of the central nervous system of the pig. Proc R Soc London 166:384-395, 1967
7. Dobbing J: The later development of the brain and its vulnerability, in Davis JA, Dobbing J (eds): Scientific Foundations of Paediatrics. Philadelphia: Saunders, 1974, pp 565-577
8. Dobbing J, Sands J: Comparative aspects of the brain growth spurt. Early Hum Dev 3:79-83, 1979 (Pubitemid 9141710)
9. Drake JM, Kestle JRW, Milner R, Cinalli G, Boop F, Piatt J Jr, et al: Randomized trial of cerebrospinal fluid shunt valve design in pediatric hydrocephalus. Neurosurgery 43:294-305, 1998 (Pubitemid 28354640)
10. Fugelseth D, Satas S, Runde M, Haga P, Thoresen M: Cardiac function and morphology studied by two-dimensional Doppler echocardiography in unsedated newborn pigs. Exp Physiol 84:69-78, 1999 (Pubitemid 29054289)
11. Ghazi-Birry HS, Brown WR, Moody DM, Challa VR, Block SM, Reboussin DM: Human germinal matrix: venous origin of hemorrhage and vascular characteristics. AJNR Am J Neuroradiol 18:218-229, 1997
12. Gluckman PD, Wyatt JS, Azzopardi D, Ballard R, Edwards AD, Ferriero DM, et al: Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial. Lancet 365:663-670, 2005 (Pubitemid 40260887)
13. Goddard J, Lewis RM, Armstrong DL, Zeller RS: Moderate, rapidly induced hypertension as a cause of intraventricular hemorrhage in the newborn beagle model. J Pediatr 96:1057-1060, 1980 (Pubitemid 10068849)
14. Haaland K, Kofstad J, Apricena F, Thoresen M: Haemoglobin is inversely related to plasma lactate and heart rate in the newborn piglet. Biol Neonate 69:350-356, 1996 (Pubitemid 26170650)
15. Hack M, Fanaroff AA: Outcomes of children of extremely low birthweight and gestational age in the 1990s. Early Hum Dev 53:193-218, 1999 (Pubitemid 28556879)
16. Johnston M, Zakharov A, Papaiconomou C, Salmasi G, Armstrong D: Evidence of connections between cerebrospinal fluid and nasal lymphatic vessels in humans, non-human primates and other mammalian species. Cerebrospinal Fluid Res 1:2, 2004
17. Khan OH, Enno TL, Del Bigio MR: Brain damage in neonatal rats following kaolin induction of hydrocephalus. Exp Neurol 299:311-320, 2006 (Pubitemid 44107914)
18. Koh L, Zakharov A, Johnston M: Integration of the subarachnoid space and lymphatics: is it time to embrace a new concept of cerebrospinal fluid absorption? Cerebrospinal Fluid Res 2:6, 2005
19. Koh L, Zakharov A, Nagra G, Armstrong D, Friendship R, Johnston M: Development of cerebrospinal fluid absorption sites in the pig and rat: connections between the subarachnoid space and lymphatic vessels in the olfactory turbinates. Anat Embryol (Berl) 211:335-344, 2006 (Pubitemid 44421073)
20. Kulkarni AV, Drake JM, Armstrong DC, Dirks PB: Measurement of ventricular size: reliability of the frontal and occipital horn ratio compared to subjective assessment. Pediatr Neurosurg 31:65-70, 1999
21. Larroche JC: Post-haemorrhagic hydrocephalus in infancy. An anatomical study. Biol Neonate 20:287-299, 1972
22. Lorenzo AV, Welch K, Conner S: Spontaneous germinal matrix and intraventricular haemorrhage in prematurely born rabbits. J Neurosurg 56:404-410, 1982 (Pubitemid 12045388)
23. Mayfrank L, Kim Y, Kissler J, Delsing P, Gilsbach JM, Schroder JM, et al: Morphological changes following experimental intraventricular haemorrhage and intraventricular fibrinolytic treatment with recombinant tissue plasminogen activator. Acta Neuropathol (Berl) 100:561-567, 2000
24. Mayfrank L, Kissler J, Raoofi R, Delsing P, Weis J, Kuker W, et al: Ventricular dilatation in experimental intraventricular hemorrhage in pigs. Characterization of cerebrospinal fluid dynamics and the effects of fibrinolytic treatment. Stroke 28:141-148, 1997 (Pubitemid 27039478)
25. Ment LR, Stewart WB, Duncan CC, Lambrecht R: Beagle puppy model of intraventricular hemorrhage. J Neurosurg 57:219-223, 1982 (Pubitemid 12099606)
26. Monteagudo A, Haratz-Rubenstein N, Timor-Tritsch IE: Biometry of the fetal brain, in Timor-Tritsch IE, Monteagudo A, Cohen HL (eds): Ultrasonography of the Prenatal and Neonatal Brain. Stamford, CT: Appleton and Lange, 1996, pp 89-146
27. O'Hayon BB, Drake JM, Ossip MG, Tuli S, Clarke M: Frontal and occipital horn ratio: a linear estimate of ventricular size for multiple imaging modalities in pediatric hydrocephalus. Pediatr Neurosurg 29:245-249, 1999 (Pubitemid 29065736)
28. Oi S, Di Rocco C: Proposal of "evolution theory in cerebrospinal fluid dynamics" and minor pathway hydrocephalus in developing immature brain. Childs Nerv Syst 22:662-669, 2006 (Pubitemid 43933686)
29. Pang D, Sclabassi RJ, Horton JA: Lysis of intraventricular blood clot with urokinase in a canine model: part 1. Canine intraventricular blood cast model. Neurosurgery 19:540-546, 1986 (Pubitemid 16006305)
30. Papile LA, Burstein J, Burstein R, Koffler H: Incidence and evolution of sub-ependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm. J Pediatr 92:529-534, 1978 (Pubitemid 8293290)
31. Park BE: Spontaneous subarachnoid hemorrhage complicated by communicating hydrocephalus: epsilon amino caproic acid as a possible predisoposing factor. Surg Neurol 11:73-80, 1979
32. Pople IK, Bayston R, Hayward RD: Infection of cerebrospinal fluid shunts in infants: a study of etiological factors. J Neurosurg 77:29-36, 1992
33. Reynolds ML, Evans CA, Reynolds EO, Saunders NR, Durbin GM, Wigglesworth JS: Intracranial haemorrhage in the preterm sheep foetus. Early Hum Dev 3:163-186, 1979 (Pubitemid 9225024)
34. Thoresen M, Haaland K, Loberg EM, Whitelaw A, Apricena F, Hanko E, et al: A piglet survival model of posthypoxic encephalopathy. Pediatr Res 40:738-48, 1996 (Pubitemid 26376569)
35. Tooley JR, Satas S, Porter H, Silver IA, Thoresen M: Head cooling with mild systemic hypothermia in anesthetized piglets is neuroprotective. Ann Neurol 53:65-72, 2003 (Pubitemid 36083830)
36. Ventriculomegaly Trial Group: Randomised trial of early tapping in neonatal posthaemorrhagic ventricular dilatation. Arch Dis Child 65 (1 Spec No):3-10, 1990
37. Ventriculomegaly Trial Group: Randomised trial of early tapping in neonatal posthaemorrhagic ventricular dilatation: results at 30 months. Arch Dis Child 70:F129-F136, 1994
38. Volpe JJ: Neurology of the Newborn. Philadelphia: WB Saunders, 2000, pp 428-493
39. Whitelaw A: Neonatal hydrocephalus-clinical assessment and non-surgical treatment, in Levene MI, Chervenak FA, Whittle MJ (eds): Fetal and Neonatal Neurology and Neurosurgery, ed 3. London: Churchill Livingstone, 2001, pp 739-752
40. Whitelaw A, Kennedy CR, Brion LP: Diuretic therapy for newborn infants with posthemorrhagic ventricular dilatation. Cochrane Database Syst Rev 2:CD002270, 2001
41. Whitelaw A, Pople I, Cherian S, Evans D, Thoresen M: Phase 1 trial of hydrocephalus after intraventricular hemorrhage in newborn infants by drainage, irrigation, and fibrinolytic therapy. Pediatrics 111:759-765, 2003 (Pubitemid 36402899)