Enhanced expression of resistin-like molecule beta in human colon cancer and its clinical significance

Digestive Diseases and Sciences

Volumn 54, Issue 2, 2009, Pages 274-281

  Zheng, Li Duan ^a   Tong, Qiang Song ^a   Weng, Mi Xia ^a   He, Jun ^a   Lv, Qing ^a   Pu, Jia Rui ^a   Jiang, Guo Song ^a   Cai, Jia Bin ^a   Liu, Yuan ^a   Hou, Xiao Hua ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Colon cancer; Immunohistochemistry; Resistin like molecule beta

Indexed keywords

KI 67 ANTIGEN; RESISTIN; RESISTIN LIKE MOLECULE BETA; TRANSCRIPTION FACTOR CDX2; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER GRADING; CANCER SURVIVAL; COLON CANCER; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER METASTASIS; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEX DIFFERENCE; TUMOR LOCALIZATION; TUMOR VOLUME;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; CHINA; COLON; COLONIC NEOPLASMS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GOBLET CELLS; HOMEODOMAIN PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; KI-67 ANTIGEN; MALE; MIDDLE AGED;

EID: 59449110329     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-008-0355-2     Document Type: Article

References (35)

1. HK Roy TC Smyrk J Koetsier TA Victor RK Wali 2005 The transcriptional repressor SNAIL is overexpressed in human colon cancer Dig Dis Sci 50 42 46
2. H Uchino H Kataoka H Itoh R Sekiya T Onitsuka M Koono 1999 Roles of intestinal trefoil factor (ITF) in human colorectal cancer: ITF suppresses the growth of colorectal carcinoma cells Hum Cell 12 181 188
3. C Laboisse A Jarry JE Branka D Merlin C Bou-Hanna G Vallette 1995 Regulation of mucin exocytosis from intestinal goblet cells Biochem Soc Trans 23 810 813
4. R Poulsom NA Wright 1993 Trefoil peptides: a newly recognized family of epithelial mucin-associated molecules Am J Physiol 265 G205 G213
5. N Aksoy OF Akinci 2004 Mucin macromolecules in normal, adenomatous, and carcinomatous colon: evidence for the neotransformation Macromol Biosci 4 483 496
6. J Byrd R Bresalier 2004 Mucins and mucin binding proteins in colorectal cancer Cancer Metastasis Rev 23 77 99
7. R Shaoul Y Okada E Cutz MA Marcon 2004 Colonic expression of MUC2, MUC5AC, and TFF1 in inflammatory bowel disease in children J Pediatr Gastroenterol Nutr 38 488 493
8. DR Taupin K Kinoshita DK Podolsky 2000 Intestinal trefoil factor confers colonic epithelial resistance to apoptosis Proc Natl Acad Sci USA 97 799 804
9. CM Steppan EJ Brown CM Wright S Bhat RR Banerjee CY Dai GH Enders DG Silberg X Wen GD Wu MA Lazar 2001 A family of tissue-specific resistin-like molecules Proc Natl Acad Sci USA 98 502 506
10. D Artis ML Wang SA Keilbaugh W He M Brenes GP Swain PA Knight DD Donaldson MA Lazar HRP Miller GA Schad P Scott GD Wu 2004 RELM{beta}/FIZZ2 is a goblet cell-specific immune-effector molecule in the gastrointestinal tract Proc Natl Acad Sci USA 101 13596 13600
11. IN Holcomb RC Kabakoff B Chan TW Baker A Gurney W Henzel C Nelson HB Lowman BD Wright NJ Skelton GD Frantz DB Tumas J Peale DL Shelton CC Hebert 2000 FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family EMBO J 19 4046 4055
12. W He ML Wang HQ Jiang CM Steppan ME Shin MC Thurnheer JJ Cebra MA Lazar GD Wu 2003 Bacterial colonization leads to the colonic secretion of RELMbeta/FIZZ2, a novel goblet cell-specific protein Gastroenterology 125 1388 1397
13. CM Steppan MA Lazar 2004 The current biology of resistin J Intern Med 255 439 447
14. AM Stutz LA Pickart A Trifilieff T Baumruker E Prieschl-Strassmayr M Woisetschlager 2003 The Th2 cell cytokines IL-4 and IL-13 regulate found in inflammatory zone 1/resistin-like molecule alpha gene expression by a STAT6 and CCAAT/enhancer- binding protein-dependent mechanism J Immunol 170 1789 1796
15. B Gerstmayer D Kusters S Gebel T Muller E Van Miert K Hofmann A Bosio 2003 Identification of RELM[gamma], a novel resistin-like molecule with a distinct expression pattern Genomics 81 588 595
16. KL Edelblum F Yan T Yamaoka DB Polk 2006 Regulation of apoptosis during homeostasis and disease in the intestinal epithelium Inflamm Bowel Dis 12 5 413 424
17. P de Santa Barbara GR van den Brink DJ Roberts 2003 Development and differentiation of the intestinal epithelium Cell Mol Life Sci 60 1322 1332
18. JL McAuley SK Linden CW Png RM King HL Pennington SJ Gendler TH Florin GR Hill V Korolik MA McGuckin 2007 MUC1 cell surface mucin is a critical element of the mucosal barrier to infection J Clin Invest 117 2313 2324
19. C Moehle N Ackermann T Langmann C Aslanidis A Kel O Kel-Margoulis A Schmitz-Madry A Zahn W Stremmel G Schmitz 2006 Aberrant intestinal expression and allelic variants of mucin genes associated with inflammatory bowel disease J Mol Med 84 1055 1066
20. M Sasaki H Ikeda Y Nakanuma 2007 Expression profiles of MUC mucins and trefoil factor family (TFF) peptides in the intrahepatic biliary system: physiological distribution and pathological significance Prog Histochem Cytochem 42 61 110
21. RR Banerjee MA Lazar 2001 Dimerization of resistin and resistin-like molecules is determined by a single cysteine J Biol Chem 276 25970 25973
22. K Kinoshita DR Taupin H Itoh DK Podolsky 2000 Distinct pathways of cell migration and antiapoptotic response to epithelial injury: structure-function analysis of human intestinal trefoil factor Mol Cell Biol 20 4680 4690
23. ML Wang ME Shin PA Knight D Artis DG Silberg E Suh GD Wu 2005 Regulation of RELM/FIZZ isoform expression by Cdx2 in response to innate and adaptive immune stimulation in the intestine Am J Physiol Gastrointest Liver Physiol 288 G1074 G1083
24. F Beck 2004 The role of Cdx genes in the mammalian gut Gut 53 1394 1396
25. JN Freund C Domon-Dell M Kedinger I Duluc 1998 The Cdx-1 and Cdx-2 homeobox genes in the intestine Biochem Cell Biol 76 957 969
26. MK Li AL Folpe 2004 CDX-2, a new marker for adenocarcinoma of gastrointestinal origin Adv Anat Pathol 11 101 105
27. H Yamamoto YQ Bai Y Yuasa 2003 Homeodomain protein CDX2 regulates goblet-specific MUC2 gene expression Biochem Biophys Res Commun 300 813 818
28. F Boudreau EHHM Rings HM van Wering RK Kim GP Swain SD Krasinski J Moffett RJ Grand ER Suh PG Traber 2002 Hepatocyte nuclear factor-1alpha, GATA-4, and caudal related homeodomain protein Cdx2 interact functionally to modulate intestinal gene transcription. Implication for the developmental regulation of the sucrase-isomaltase gene J Biol Chem 277 31909 31917
29. F Drummond J Sowden K Morrison YH Edwards 1996 The caudal-type homeobox protein Cdx-2 binds to the colon promoter of the carbonic anhydrase 1 gene Eur J Biochem 236 670 681
30. O Lorentz I Duluc AD Arcangelis P Simon-Assmann M Kedinger JN Freund 1997 Key role of the Cdx2 homeobox gene in extracellular matrix-mediated intestinal cell differentiation J Cell Biol 139 1553 1565
31. T Sakaguchi X Gu HM Golden E Suh DB Rhoads HC Reinecker 2002 Cloning of the human claudin-2 5′-flanking region revealed a TATA-less promoter with conserved binding sites in mouse and human for caudal-related homeodomain proteins and hepatocyte nuclear factor-1alpha J Biol Chem 277 21361 21370
32. PG Traber GD Wu W Wang 1992 Novel DNA-binding proteins regulate intestine-specific transcription of the sucrase-isomaltase gene Mol Cell Biol 12 3614 3627
33. DT Dang CS Mahatan LH Dang IA Agboola VW Yang 2001 Expression of the gut-enriched Krüppel-like factor (Krüppel-like factor 4) gene in the human colon cancer cell line RKO is dependent on CDX2 Oncogene 20 4884 4890
34. M Marchetti E Caliot E Pringault 2003 Chronic acid exposure leads to activation of the cdx2 intestinal homeobox gene in a long-term culture of mouse esophageal keratinocytes J Cell Sci 116 1429 1436
35. RW Phillips HF Frierson Jr CA Moskaluk 2003 Cdx2 as a marker of epithelial intestinal differentiation in the esophagus Am J Surg Pathol 27 1442 1447