Pharmacological in vivo test to evaluate the bioavailability of some St john's wort innovative oral preparations

Phytotherapy Research

Volumn 23, Issue 2, 2009, Pages 197-205

  Isacchi, B ^a   Galeotti, N ^a   Bergonzi, M C ^a   Ghelardini, C ^a   Bilia, A R ^a   Vincieri, F F ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

cyclodextrin; In vivo 'porsolt test'; Micelles; St john's wort; Water solubility of formulations

Indexed keywords

AMITRIPTYLINE; BETA CYCLODEXTRIN; BIAPIGENIN; CLOMIPRAMINE; DODECYL SULFATE SODIUM; FLAVONOID; HYPERFORIN; HYPERICIN; HYPERICUM PERFORATUM EXTRACT; OCTANOYL 6 O ASCORBIC ACID; SURFACTANT; UNCLASSIFIED DRUG; ANTIDEPRESSANT AGENT; BETA CYCLODEXTRIN DERIVATIVE; EXCIPIENT; PLANT EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEPRESSION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DOSAGE FORM COMPARISON; DRUG EFFECT; DRUG FORMULATION; DRUG SOLUBILITY; LIPOPHILICITY; MALE; MICELLE; MOUSE; NONHUMAN; ANIMAL; BIOAVAILABILITY; CHEMISTRY; DOSE RESPONSE; DRUG STABILITY; HYPERICUM; MEDICINAL PLANT; ORAL DRUG ADMINISTRATION; SOLUBILITY; SWIMMING;

MUS;

ADMINISTRATION, ORAL; ANIMALS; ANTIDEPRESSIVE AGENTS; BETA-CYCLODEXTRINS; BIOLOGICAL AVAILABILITY; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG STABILITY; EXCIPIENTS; HYPERICUM; MALE; MICE; MICELLES; PLANT EXTRACTS; PLANTS, MEDICINAL; SODIUM DODECYL SULFATE; SOLUBILITY; SWIMMING;

EID: 59449108915     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.2586     Document Type: Article

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