Concurrent in vitro release of silver sulfadiazine and bupivacaine from semi-interpenetrating networks for wound management

Journal of Burn Care and Research

Volumn 30, Issue 1, 2009, Pages 98-104

  Kleinbeck, Kyle R ^a   Bader, Rebecca A ^a   Kao, Weiyuan John ^a,b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b University of Wisconsin Madison   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUPIVACAINE; SULFADIAZINE SILVER;

ANTIMICROBIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG RELEASE; IN VITRO STUDY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN; PSEUDOMONAS AERUGINOSA; SKIN INJURY; STAPHYLOCOCCUS AUREUS;

ANESTHETICS, LOCAL; ANTI-INFECTIVE AGENTS, LOCAL; BUPIVACAINE; BURNS; CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; METHICILLIN RESISTANCE; OCCLUSIVE DRESSINGS; POLYMERS; PSEUDOMONAS AERUGINOSA; SILVER SULFADIAZINE; STAPHYLOCOCCUS AUREUS; WOUND HEALING;

EID: 59449096855     PISSN: 1559047X     EISSN: 15590488     Source Type: Journal    
DOI: 10.1097/BCR.0b013e3181921ed9     Document Type: Article

References (22)

1. Ayello EA. New evidence for an enduring wound-healing concept: moisture control. J Wound Ostomy Continence Nurs 2006;33:Sl-2.
2. Brett DW. A review of moisture-control dressings in wound care. J Wound Ostomy Continence Nurs 2006;33:S3-8.
3. Stevens KR, Einerson NJ, Burmania JA, Kao WJ. In vivo biocompatibility of gelatin-based hydrogels and interpenetrating networks. J Biomater Sci 2002;13:1353-66.
4. Waldeck H, Chung AS, Kao WJ. Interpenetrating polymer networks containing gelatin modified with PEGylated RGD and soluble KGF: synthesis, characterization, and application in in vivo critical dermal wound. J Biomed Mater Res A 2007; 82:861-71.
5. Einerson NJ, Stevens KR, Kao WJ. Synthesis and physico-chemical analysis of gelatin-based hydrogels for drug carrier matrices. Biomaterials 2002;24:509-23.
6. Witte RP, Blake AJ, Palmer C, Kao WJ. Analysis of poly(ethylene glycol)-diacrylate macromer polymerization within a multicomponent semi-interpenetrating polymer network system. J Biomed Mater Res A 2004;71:508-18.
7. Sawhney AS, Pathak CP, Hubbell JA. Interfacial photopolymerization of poly(ethylene glycol)-based hydrogels upon alginate-poly(l-lysine) microcapsules for enhanced biocompatibility. Biomaterials 1993;14:1008-16.
8. Phillips JM, Kao WJ. Macrophage adhesion on gelatin-based interpenetrating networks grafted with PEGylated RGD. Tissue Eng 2005;11:964-73.
9. Lansdown ABG. Silver 1: its antibacterial properties and mechanism of action. J Wound Care 2002;11:125-30.
10. Lowbury EJL. Problems of resistance in open wounds and burns. In: Mouton RP, Brumfitt W, Hamilto-Miller JMT, editors. The rational choice of antibacterial agents. London: Kluwer Harrap; 1975. p. 18-31.
11. Silver sulfadiazine. Med Lett Drugs Ther 1974;16:43-4.
12. Silver S, Phung LT, Silver G. Silver as biocides in burn and wound dressings and bacterial resistance to silver compounds. J Ind Microbiol Biotechnol 2006;33:627-34.
13. Bjarnsholt T, Kirketerp-Moller K, Kristiansen S, et al. Silver against Pseudomonas aeruginosa biofilms. APMIS 2007;115: 921-8.
14. Fox CL, Rappole BW, Stanford W. Control of Pseudomonas infection in burns by silver sulfadiazine. Surg Gynecol Obstet 1969;128:1021-7.
15. Modak SM, Fox CLJ. Sulfadiazine silver-resistant Pseudomonas in burns. New topical agents. Arch Surg 1981;116: 854-7.
16. Klasen HJ. A historical review of the use of silver in the treatment of burns. II. Renewed interest for silver. Burns 2000; 26:131-8.
17. Gallagher G, Rae CP, Kinsella J. Treatment of pain in severe burns. Am J Clin Dermatol 2000;1:325-9.
18. Chou R, Clark E, Helfand M. Comparative efficacy and safety of long-acting oral opioids for chronic non-cancer pain: a systematic review. J Pain Symptom Manage 2003;26: 1026-48.
19. Katzung BG. Basic and clinical pharmacology. 9th ed. NY: McGraw-Hill; 1997. p. 418-27.
20. Dinesh ND, Nagaraja P, Rangappa KS. Sensitive spectrophotometric methods for the analysis of some anesthetic drugs. Indian J Pharm Sci 2002;64:485-8.
21. Blanco MD, Bernardo MV, Teijon C, Sastre RL, Teijon RJ. Transdermal application of bupivacaine-loaded poly(acrylamide(A)-co-monomethyl itaconate) hydrogels. Int J Pharm 2003;255:99-107.
22. Hadjipavlou-Litina D, Kontogiorgis C, Pontiki E, Dakanali MA, Katerinopoulos HE. Anti-inflammatory and antioxidant activity of coumarins designed as potential fluorescent zinc sensors. J Enzyme Inhib Med Chem 2007;22:292-7.