Clinical features of ankylosing spondylitis may correlate with HLA-B27 polymorphism

Rheumatology International

Volumn 29, Issue 4, 2009, Pages 389-392

  Wu, Zhen ^a   Lin, Zhiming ^a   Wei, Qiujing ^a   Gu, Jieruo ^a  

^a THE THIRD AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

Author keywords

Ankylosing spondylitis; HLA B27; Polymorphism

Indexed keywords

HLA B27 ANTIGEN;

ADULT; ANKYLOSING SPONDYLITIS; ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE DURATION; DNA POLYMORPHISM; FEMALE; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ADULT; AGE OF ONSET; CHINA; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HLA-B27 ANTIGEN; HUMANS; MALE; POLYMORPHISM, GENETIC; PROGNOSIS; SPONDYLITIS, ANKYLOSING;

EID: 59449090577     PISSN: 01728172     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00296-008-0743-0     Document Type: Article

References (27)

1. MA Blanco-Gelaz A Lopez-Vazquez S Garcia-Fernandez 2001 Genetic variability, molecular evolution, and geographic diversity of HLA-B27 Hum Immunol 62 9 1042 1050
2. J Robinson MJ Waller SC Fail 2006 The IMGT/HLA and IPD databases Hum Mut 27 1192 1199
3. J Sieper M Rudwaleit MA Khan 2006 Concepts and epidemiology of spondyloarthritis Best Pract Res Clin Rheumatol 20 3 401 417
4. MA Brown LG Kennedy AJ MacGregor 1997 Susceptibility to ankylosing spondylitis in twins: the role of genes, HLA, and the environment Arthritis Rheum 40 10 1823 1828
5. AM Sims M Barnardo I Herzberg 2007 Non-B27 MHC associations of ankylosing spondylitis Genes Immun 8 2 115 123
6. SH Laval A Timms S Edwards 2001 Whole-genome screening in ankylosing spondylitis: evidence of non-MHC genetic-susceptibility loci Am J Hum Genet 68 4 918 926
7. YH Lee YH Rho SJ Choi 2005 Ankylosing spondylitis susceptibility loci defined by genome-search meta-analysis J Hum Genet 50 9 453 459
8. KW Carter A Pluzhnikov AE Timms 2007 Combined analysis of three whole genome linkage scans for Ankylosing Spondylitis Rheumatology (Oxford) 46 5 763 771
9. M Breban C Miceli-Richard E Zinovieva 2006 The genetics of spondyloarthropathies Joint Bone Spine 73 355 362
10. J Freeston N Barkham E Hensor 2007 Ankylosing spondylitis, HLA-B27 positivity and the need for biologic therapies Joint Bone Spine 72 4 140 143
11. MA Khan I Kushner WE Braun 1977 Comparison of clinical features in HLA-B27 positive and negative patients with ankylosing spondylitis Arthritis Rheum 20 4 909 912
12. MA Khan A Mathieu R Sorrentino 2007 The pathogenetic role of HLA-B27 and its subtypes Autoimmun Rev 6 3 183 189
13. J Hamersma LR Cardon L Bradbury 2001 Is disease severity in ankylosing spondylitis genetically determined? Arthritis Rheum 44 6 1396 1400
14. R Said-Nahal C Miceli-Richard JM Berthelot 2000 The familial form of spondylarthropathy: a clinical study of 115 multiplex families. Groupe Francais d'Etude Genetique des Spondylarthropathies Arthritis Rheum 43 6 1356 1365
15. R Porcher R Said-Nahal MA D'Agostino 2005 Two major spondylarthropathy phenotypes are distinguished by pattern analysis in multiplex families Arthritis Rheum 53 2 263 271
16. R Said-Nahal C Miceli-Richard MA D'Agostino 2001 Phenotypic diversity is not determined by independent genetic factors in familial spondylarthropathy Arthritis Rheum 45 6 478 484
17. MA Brown S Brophy L Bradbury 2003 Identification of major loci controlling clinical manifestations of ankylosing spondylitis Arthritis Rheum 48 8 2234 2239
18. J Braun J Brandt J Listing 2002 Treatment of active ankylosing spondylitis with infliximab: a randomised controlled multicentre trial Lancet 359 9313 1187 1193
19. M Diedrichs-Mohring G Wildner 2005 Immunostimulatory and immunomodulatory peptides derived from the alpha1 domain of HLA-B27 in experimental autoimmune diseases in Lewis rats Immunobiology 209 10 711 717
20. M Ramos I Alvarez L Sesma 2002 Molecular Mimicry of an HLA-B27-derived Ligand of Arthritis-linked Subtypes with Chlamydial Proteins J Biol Chem 277 40 37573 37581
21. E Frauendorf H von Goessel E May 2003 HLA-B27-restricted T cells from patients with ankylosing spondylitis recognize peptides from B*2705 that are similar to bacteria-derived peptides Clin Exp Immunol 134 2 351 359
22. M Luthra-Guptasarma B Singh 2004 HLA-B27 lacking associated beta2-microglobulin rearranges to auto-display or cross-display residues 169-181: a novel molecular mechanism for spondyloarthropathies FEBS Lett 575 1-3 1 8
23. WC Tsai CJ Chen JH Yen 2002 Free HLA class I heavy chain-carrying monocytes-a potential role in the pathogenesis of spondyloarthropathies J Rheumatol 29 5 966 972
24. E Jaakkola I Herzberg K Laiho 2006 Finnish HLA studies confirm the increased risk conferred by HLA-B27 homozygosity in ankylosing spondylitis Ann Rheum Dis 65 6 775 780
25. A Cauli G Dessole MT Fiorillo 2002 Increased level of HLA-B27 expression in ankylosing spondylitis patients compared with healthy HLA-B27-positive subjects: a possible further susceptibility factor for the development of disease Rheumatology (Oxford) 41 12 1375 1379
26. LA Bird CA Peh S Kollnberger 2003 Lymphoblastoid cells express HLA-B27 homodimers both intracellularly and at the cell surface following endosomal recycling Eur J Immunol 33 3 748 759
27. TM Tran N Satumtira ML Dorris 2004 HLA-B27 in transgenic rats forms disulfide-linked heavy chain oligomers and multimers that bind to the chaperone BiP J Immunol 172 8 5110 5119