Low osmolar contrast medium induces cellular injury and disruption of calcium homeostasis in rat glomerular endothelial cells in vitro

Toxicology Letters

Volumn 185, Issue 2, 2009, Pages 124-131

  Zhao, Jinghong ^a   Huang, Yunjian ^a   Song, Yaoming ^a   Zhao, Xiaohui ^a   Jin, Jun ^a   Wang, Junping ^a   Huang, Lan ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Calcium homeostasis; Cell viability; Contrast medium; Glomerular endothelial cells; Injury

Indexed keywords

CALCIUM; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; IOVERSOL; LACTATE DEHYDROGENASE;

ANIMAL CELL; ANIMAL CELL CULTURE; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CELL DAMAGE; CELL DEATH; CELL DISRUPTION; CELL NUCLEUS; CELL VIABILITY; CONCENTRATION RESPONSE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME RELEASE; GLOMERULOSA CELL; MALE; NITROBLUE TETRAZOLIUM TEST; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; APOPTOSIS; BENZIMIDAZOLES; BLOTTING, WESTERN; CALCIUM; CELL NUCLEUS; CELL SURVIVAL; CELLS, CULTURED; CONTRAST MEDIA; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; HOMEOSTASIS; KIDNEY GLOMERULUS; L-LACTATE DEHYDROGENASE; MALE; OSMOLAR CONCENTRATION; PROPIDIUM; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS; TETRA;

EID: 59349105096     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2008.12.009     Document Type: Article

References (36)

1. Akis N., and Madaio M.P. Isolation, culture, and characterization of endothelial cells from mouse glomeruli. Kidney Int. 65 (2004) 2223-2227
2. Andrade L., Campos S.B., and Seguro A.C. Hypercholesterolemia aggravates radiocontrast nephrotoxicity: protective role of l-arginine. Kidney Int. 53 (1998) 1736-1742
3. Arici M., Erdem Y., Altun B., Balkanci F., Yasavul U., Turgan C., and Caglar S. Severe renal vasoconstriction and anuria after intravenous urography in a patient with renal impairment. Am. J. Kidney Dis. 28 (1996) 454-456
4. Beeri R., Symon Z., Brezis M., Ben-Sasson S.A., Baehr P.H., Rosen S., and Zager R.A. Rapid DNA fragmentation from hypoxia along the thick ascending limb of rat kidneys. Kidney Int. 47 (1995) 1806-1810
5. Brown J.R., DeVries J.T., Piper W.D., Robb J.F., Hearne M.J., Ver Lee P.M., Kellet M.A., Watkins M.W., Ryan T.J., Silver M.T., Ross C.S., MacKenzie T.A., O'Connor G.T., Malenka D.J., and Northern New England Cardiovascular Disease Study Group. Serious renal dysfunction after percutaneous coronary interventions can be predicted. Am. Heart J. 155 (2008) 260-266
6. Conen D., Buerkle G., Perruchoud A.P., Buettner H.J., and Mueller C. Hypertension is an independent risk factor for contrast nephropathy after percutaneous coronary intervention. Int. J. Cardiol. 110 (2006) 237-241
7. D'Andrea D.M., Coupaye-Gerard B., Kleyman T.R., Foster M.H., and Madaio M.P. Lupus autoantibodies interact directly with distinct glomerular and vascular cell surface antigens. Kidney Int. 49 (1996) 1214-1221
8. Drescher P., Rauch D., Knes J.M., and Madsen P.O. Contrast medium induced renal vasoconstriction, role of alpha receptors. Scand. J. Urol. Nephrol. Suppl. 172 (1995) 103-108
9. Fanning N.F., Manning B.J., Buckley J., and Redmond H.P. Iodinated contrast media induce neutrophil apoptosis through a mitochondrial and caspase mediated pathway. Br. J. Radiol. 75 (2002) 861-873
10. Farber J.L. Biology of disease: membrane injury and calcium homeostasis in the pathogenesis of coagulative necrosis. Lab. Invest. 47 (1982) 114-123
11. Gogvadze V., and Orrenius S. Mitochondrial regulation of apoptotic cell death. Chem. Biol. Interact. 163 (2006) 4-14
12. Hajnoczky G., Davis E., and Madesh M. Calcium and apoptosis. Biochem. Biophys. Res. Commun. 304 (2003) 445-454
13. Hardiek K., Katholi R.E., Ramkumar V., and Deitrick C. Proximal tubule cell response to radiographic contrast media. Am. J. Physiol. Renal Physiol. 280 (2001) F61-F70
14. Heinrich M.C., Kuhlmann M.K., Grqic A., Heckmann M., Kramann B., and Uder M. Cytotoxic effects of ionic high-osmolar, nonionic monomeric, and nonionic iso-osmolar dimeric iodinated contrast media on renal tubular cells in vitro. Radiology 235 (2005) 843-849
15. Heinrich M.C., Kuhlmann M.K., Kohlbacher S., Scheer M., Grqic A., Heckmann M., and Uder M. Cytotoxicity of iodinated and gadolinium-based contrast agents in renal tubular cells at angiographic concentrations: in vitro study. Radiology 242 (2007) 425-434
16. Hirano K., Huang X.Q., Yoshikoshi A., Takatasuki H., and Sakanishi A. Influence of angiography contrast media on viability of endotherial cells in cultures. Colloid Surface B 33 (2004) 205-210
17. Hussain S.M., and Frazier J.M. Cellular toxicity of hydrazine in primary hepatocytes. Toxicol. Sci. 69 (2002) 424-432
18. Izban K.F., Wrone-Smith T., His E.D., Schnitzer B., Quevedo M.E., and Alkan S. Characterization of the interleukin-1beta-converting enzyme/ced-3-family protease, caspase-3/CPP32, in Hodgkin's disease: lack of caspase-3 expression in nodular lymphocyte predominance Hodgkin's disease. Am. J. Pathol. 154 (1999) 1439-1447
19. Kim J.S., He L., and Lemasters J.J. Mitochondrial permeability transition: a common pathway to necrosis and apoptosis. Biochem. Biophys. Res. Commun. 304 (2003) 463-470
20. Kowaltowski A.J., Vercesi A.E., and Fiskum G. Bcl-2 prevents mitochondrial permeability transition and cytochrome c releasing via maintence of reduced pyridine nucleotides. Cell. Death. Differ. 7 (2000) 903-910
21. Liss P., Persson P.B., Hansell P., and Lagerqvist B. Renal failure in 57925 patients undergoing coronary procedures using iso-osmolar or low-osmolar contrast media. Kidney Int. 70 (2006) 1811-1817
22. Liu X., Van Vleet T., and Schnellmann R.G. The role of calpain in oncotic cell death. Annu. Rev. Pharmacol. Toxicol. 44 (2004) 349-370
23. Mehran R., and Nikolsky E. Contrast-induced nephropathy: definition, epidemiology, and patients at risk. Kidney Int. Suppl. 100 (2006) S11-S15
24. Morcos S.K., Thomsen H.S., and Webb J.A. Contrast-media-induced nephrotoxicity: a consensus report. Eur. Radiol. 9 (1999) 1602-1613
25. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65 (1983) 55-63
26. Orrenius S., Zhivotovsky B., and Nicotera P. Regulation of cell death: the calcium-apoptosis link. Nat. Rev. Mol. Cell Biol. 4 (2003) 552-565
27. Robertson J.D., Orrenius S., and Zhivotovsky B. Review: nuclear events in apoptosis. J. Struct. Biol. 129 (2000) 346-358
28. Romano G., Briguori C., Quintavalle C., Zanca C., Rivera N.V., Colombo A., and Condorelli G. Contrast agents and renal cell apoptosis. Eur. Heart J. 29 (2008) 2569-2576
29. Rudnick M.R., Goldfarb S., Wexler L., Ludbrook P.A., Murphy M.J., Halpern E.F., Hill J.A., Winniford M., Cohen M.B., and VanFossen D.B. Nephrotoxicity of ionic and nonionic contrast media in 1196 patients: a randomized trial. Kidney Int. 47 (1995) 254-261
30. Sawmiller C.J., Powell R.J., Quader M., Dudrick S.J., and Sumpio B.E. The differential effect of contrast agents on endothelial cell and smooth muscle cell growth in vitro. J. Vasc. Surg. 27 (1998) 1128-1140
31. Wasaki M., Sugimoto J., and Shirota K. Glucose alters the susceptibility of mesangial cells to contrast media. Invest. Radiol. 37 (2001) 355-362
32. 2+-dependent necrotic cell death through Calpain-triggered mitochondrial depolarization and reactive oxygen species-mediated inhibition of nuclear factor-KB activity. Chem. Res. Toxicol. 20 (2007) 406-415
33. Yano T., Itoh Y., Sendo T., Kubota T., and Oishi R. Cyclic AMP reverses radiocontrast media-induced apoptosis in LLC-PK1 cells by activating A kinase/PI3 kinase. Kidney Int. 64 (2003) 2052-2063
34. Zager R.A., Johnson A.C., and Hanson S.Y. Radiographic contrast media-induced tubular injury: evaluation of oxidant stress and plasma membrane integrity. Kidney Int. 64 (2003) 128-139
35. Zhang H., Holt C.M., Malik N., Shepherd L., and Morcos S.K. Effects of radiographic contrast media on proliferation and apoptosis of human vascular endothelial cells. Br. J. Radiol. 73 (2000) 1034-1041
36. Zou H., Li Y., Liu X., and Wang X. An APAF-1 cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J. Biol. Chem. 274 (1999) 11549-11556