Taming the induced folding of drug-targeted kinases

Trends in Pharmacological Sciences

Volumn 30, Issue 2, 2009, Pages 66-71

  Fernández, Ariel ^a   Bazán, Soledad ^a   Chen, Jianping ^a  

^a Rice University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; IMATINIB; METHIONINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 12; MITOGEN ACTIVATED PROTEIN KINASE 14; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG; WBZ 4;

AMINO ACID ANALYSIS; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONFORMATIONAL TRANSITION; DRUG DESIGN; DRUG SPECIFICITY; DRUG TARGETING; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; STRUCTURE ANALYSIS; VALIDATION STUDY;

ANTINEOPLASTIC AGENTS; BINDING SITES; DRUG DELIVERY SYSTEMS; DRUG DESIGN; LIGANDS; MODELS, MOLECULAR; PIPERAZINES; PROTEIN FOLDING; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; PYRIMIDINES;

EID: 59349088203     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tips.2008.11.001     Document Type: Article

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