Hypoxia regulates iNOS expression in human normal peritoneal and adhesion fibroblasts through nuclear factor kappa B activation mechanism

Fertility and Sterility

Volumn 91, Issue 2, 2009, Pages 616-621

  Jiang, Zhong L ^a   Fletcher, Nicole M ^a   Diamond, Michael P ^a   Abu Soud, Husam M ^a   Saed, Ghassan M ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

adhesion; Fibroblasts; hypoxia; I B ; iNOS; NF B; peritoneum; real time RT PCR

Indexed keywords

CYTOPLASM PROTEIN; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA;

ARTICLE; CELL ADHESION; CELL TYPE; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOXIA; OUTCOME ASSESSMENT; PERITONEUM; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UNIVERSITY HOSPITAL; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL HYPOXIA; CELLS, CULTURED; HUMANS; I-KAPPA B PROTEINS; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PERITONEAL DISEASES; PERITONEUM; PHOSPHORYLATION; PROSPECTIVE STUDIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS; TISSUE ADHESIONS; UP-REGULATION;

EID: 59249103339     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2007.11.059     Document Type: Article

References (39)

1. Diamond M.P., Daniell J.F., Feste J., Surrey M.W., McLaughlin D.S., and Friedman S. Adhesion reformation and de novo adhesion formation after reproductive pelvic surgery. Fertil Steril 47 (1987) 864-866
2. Diamond M.P., and Hershlag A. Adhesion formation/reformation. Prog Clin Biol Res 358 (1990) 23-33
3. Ellis H. The clinical significance of adhesions: focus on intestinal obstruction. Eur J Surg Suppl 577 (1997) 5-9
4. Saed G.M., Zhang W., and Diamond M.P. Molecular characterization of fibroblasts isolated from human peritoneum and adhesions. Fertil Steril 75 (2001) 763-768
5. Saed G.M., and Diamond M.P. Hypoxia-induced irreversible up-regulation of type I collagen and transforming growth factor-beta1 in human peritoneal fibroblasts. Fertil Steril 78 (2002) 144-147
6. Saed G.M., and Diamond M.P. Apoptosis and proliferation of human peritoneal fibroblasts in response to hypoxia. Fertil Steril 78 (2002) 137-143
7. Saed G.M., Abu-Soud H.M., and Diamond M.P. Role of nitric oxide in apoptosis of human peritoneal and adhesion fibroblasts after hypoxia. Fertil Steril 82 Suppl 3 (2004) 1198-1205
8. Jiang Z, Zhu XP, Diamond MP, Abu-Soud HM, Saed GM. Nitric oxide synthase isoforms expression in fibroblasts isolated from human normal peritoneum and adhesion tissues. In press.
9. Manjeet K.R., and Ghosh B. Quercetin inhibits LPS-induced nitric oxide and tumor necrosis factor-alpha production in murine macrophages. Int J Immunopharmacol 21 (1999) 435-443
10. Kokura S., Yoshida N., and Yoshikawa T. Anoxia/reoxygenation-induced leukocyte-endothelial cell interactions. Free Radic Biol Med 33 (2002) 427-432
11. Haddad J.J. Science review: redox and oxygen-sensitive transcription factors in the regulation of oxidant-mediated lung injury: role for hypoxia-inducible factor-1alpha. Crit Care 7 (2003) 47-54
12. Saadi S., Wrenshall L.E., and Platt J.L. Regional manifestations and control of the immune system. FASEB J 16 (2002) 849-856
13. Lewis J.S., Lee J.A., Underwood J.C., Harris A.L., and Lewis C.E. Macrophage responses to hypoxia: relevance to disease mechanisms. J Leukocyte Biol 66 (1999) 889-900
14. Guo G., and Bhat N.R. Hypoxia/reoxygenation differentially modulates NF-kappaB activation and iNOS expression in astrocytes and microglia. Antioxid Redox Signal 8 (2006) 911-918
15. Saed G.M., Zhao M., Diamond M.P., and Abu-Soud H.M. Regulation of inducible nitric oxide synthase in post-operative adhesions. Hum Reprod 21 (2006) 1605-1611
16. Saed GM, Lu H, Jiang ZL, Abuolba S, Abu-Soud HM, Diamond MP. Cross talk between inducible nitric oxide syntheses (iNOS) and myeloperoxidase (MPO) in fibroblasts isolated from normal peritoneal and adhesion tissues. (submitted).
17. Fujimori K., Fujitani Y., Kadoyama K., Kumanogoh H., Ishikawa K., and Urade Y. Regulation of lipocalin-type prostaglandin D synthase gene expression by Hes-1 through E-box and interleukin 1-beta via two NF-kappa B elements in rat leptomeningeal cells. J Biol Chem 278 (2003) 6018-6026
18. Jiang B., Xu S., Brecher P., and Cohen R.A. Growth factors enhance interleukin 1-beta induced persistent activation of nuclear factor kappa B in rat vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 22 (2002) 1811-1816
19. Jacobs M.D., and Harrison S.C. Structure of an I kappa B alpha/NF-kappa B complex. Cell 95 (1998) 749-758
20. Huguet C., Crepieux P., and Laudet V. Rel/NF-kappa B transcription factors and I kappa B inhibitors: evolution from a unique common ancestor. Oncogene 15 (1997) 2965-2974
21. Whiteside S.T., and Israel A. I kappa B proteins: structure, function and regulation. Semin Cancer Biol 8 (1997) 75-82
22. Yamamoto Y., and Gaynor R.B. I kappa B kinases: key regulators of the NF-kappa B pathway. Trends Biochem Sci 29 (2004) 72-79
23. Brockman J.A., Scherer D.C., Mckinsey T.A., Hall S.M., Qi X., Lee W.Y., et al. Coupling of a signal response domain in IκBα to multiple pathways for NF-κB activation. Mol Cell Biol 15 (1995) 2809-2818
24. Yang L., Chen H., and Qwarnstrom E. Degradation of I kappa B alpha is limited by a postphosphorylation/ubiquitination event. Biochem Biophys Res Commun 285 (2001) 603-608
25. Dejardin E., Deregowski V., Chapelier M., Jacobs N., Gielen J., Merville M.P., et al. Regulation of NF-kappaB activity by I kappa B-related proteins in adenocarcinoma cells. Oncogene 18 (1999) 2567-2577
26. Wulczyn F.G., Krappmann D., and Scheidereit C. Signal-dependent degradation of IκBα is mediated by an inducible destruction box that can be transferred to NF-κB, Bcl-3 or p53. Nucleic Acids Res 26 (1998) 1724-1730
27. Traenckner E.B., Wilk S., and Baeuerle P.A. A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B. EMBO J 13 (1994) 5433-5441
28. Renard P., Percherancier Y., Kroll M., Thomas D., Virelizier J.L., Arenzana-Seisdedos F., et al. Inducible NF-kappa B activation is permitted by simultaneous degradation of nuclear I kappa B alpha. J Biol Chem 275 (2000) 15193-15199
29. Wang W., Abbruzzese J.L., Evans D.B., Larry L., Cleary K.R., and Chiao P.J. The nuclear factor-κB RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells. Clin Cancer Res 5 (1999) 119-127
30. Moro M.A., De Alba J., Leza J.C., Lorenzo P., Fernandez A.P., Bentura M.L., et al. Neuronal expression of inducible nitric oxide synthase after oxygen and glucose deprivation in rat forebrain slices. Eur J Neurosci 10 (1998) 445-456
31. Palombella V.J., Rando O.J., Goldberg A.L., and Maniatis T. The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B. Cell 78 (1994) 773-785
32. Imbert V., Rupec R.A., Livolsi A., Pahl H.L., Traenckner E.B., Mueller-Dieckmann C., et al. Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha. Cell 86 (1996) 787-798
33. Liu Z.G., Hsu H., Goeddel D.V., and Karin M. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death. Cell 87 (1996) 565-576
34. Gozal E., Sinakajornboon N., and Gozal D. NF-kappaB induction during in vivo hypoxia in dorsocaudal brain stem of rat: effect of MK-801 and L-NAME. J Appl Physiol 85 (1998) 372-376
35. Irving E.A., and Bamford M. Role of mitogen- and stress-activated kinases in ischemic injury. J Cereb Blood Flow Metab 22 (2002) 631-647
36. Gabriel C., Justicia C., Camins A., and Planas A.M. Activation of nuclear factor-kappaB in the rat brain after transient focal ischemia. Brain Res Mol Brain Res 65 (1999) 61-69
37. Stanimirovic D., Zhang W., Howlett C., Lemieux P., and Smith C. Inflammatory gene transcription in human astrocytes exposed to hypoxia: roles of the nuclear factor-B and autocrine stimulation. J Neuroimmunol 119 (2001) 365-376
38. Goldring C.E., Narayanan R., Lagadec P., and Jeannin J.F. Transcriptional inhibition of the inducible nitric oxide synthase gene by competitive binding of NF-kappa B/Rel proteins. Biochem Biophys Res Commun 209 (1995) 73-79
39. Xie Q.W., Kashiwabara Y., and Nathan C. Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase. J Biol Chem 269 (1994) 4705-4708