Stabilizing effects of eicosapentaenoic acid on Kv1.5 channel protein expressed in mammalian cells

European Journal of Pharmacology

Volumn 604, Issue 1-3, 2009, Pages 93-102

  Koshida, Shunya ^a   Kurata, Yasutaka ^b   Notsu, Tomomi ^a   Hirota, Yutaka ^a   Kuang, Ting Y ^a   Li, Peili ^a   Bahrudin, Udin ^a   Harada, Shingo ^a   Miake, Junichiro ^c   Yamamoto, Yasutaka ^a   Hoshikawa, Yoshiko ^a   Igawa, Osamu ^c   Higaki, Katsumi ^c   Soma, Masaaki ^d   Yoshida, Akio ^a   Ninomiya, Haruaki ^c   Shiota, Goshi ^e   Shirayoshi, Yasuaki ^a   Hisatome, Ichiro ^a  

^a Institute of Regenerative Medicine and Biofunction   (Japan)

^b KANAZAWA MEDICAL UNIVERSITY   (Japan)

^c TOTTORI UNIVERSITY   (Japan)

^d MOCHIDA PHARMACEUTICAL CO   (Japan)

^e Regenerative Therapeutics   (Japan)

Author keywords

DHA; EPA; Kv1.5; Ultra rapid delayed rectifier K+ channel current

Indexed keywords

4 AMINOPYRIDINE; BREFELDIN A; COLCHICINE; DELAYED RECTIFIER POTASSIUM CHANNEL; DOCOSAHEXAENOIC ACID; ICOSAPENTAENOIC ACID; MESSENGER RNA; POTASSIUM CHANNEL KV1.5; PROTEIN DERIVATIVE; SYNAPSE ASSOCIATED PROTEIN 97; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CELLULAR DISTRIBUTION; CERCOPITHECIDAE; CHANNEL GATING; CONTROLLED STUDY; DOSE RESPONSE; ENDOPLASMIC RETICULUM; FIBROBLAST; GOLGI COMPLEX; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; RAT;

ACTION POTENTIALS; ANIMALS; BLOTTING, WESTERN; CERCOPITHECUS AETHIOPS; COS CELLS; DOCOSAHEXAENOIC ACIDS; DOSE-RESPONSE RELATIONSHIP, DRUG; EICOSAPENTAENOIC ACID; FIBROBLASTS; IMMUNOPRECIPITATION; KV1.5 POTASSIUM CHANNEL; PATCH-CLAMP TECHNIQUES; PEPTIDES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN STABILITY; RATS; RATS, INBRED WKY; RECOMBINANT FUSION PROTEINS; THIOCTIC ACID; TRANSFECTION;

EID: 59249098135     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.12.016     Document Type: Article

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