Function of the Wingless Signaling Pathway in Drosophila

Methods in Molecular Biology

Volumn 469, Issue , 2008, Pages 115-125

  Gonsalves, Foster C ^a   DasGupta, Ramanuj ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Drosophila; Embryogenesis; Organogenesis; Patterning; Polarity; Signaling pathways; Wingless

Indexed keywords

DROSOPHILA MELANOGASTER;

DROSOPHILA PROTEIN; UNCLASSIFIED DRUG; WG PROTEIN, DROSOPHILA; WNT1 PROTEIN;

ANIMAL; DROSOPHILA MELANOGASTER; GENETICS; HISTOLOGY; METABOLISM; MORPHOGENESIS; PHYSIOLOGY; PRENATAL DEVELOPMENT; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; BODY PATTERNING; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; SIGNAL TRANSDUCTION; WNT1 PROTEIN;

EID: 59249087221     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-60327-469-2_10     Document Type: Review

References (54)

1. Nusslein-Volhard, C., Wieschaus, E. (1980) Mutations affecting segment number and polarity in Drosophila. Nature 287, 795-801.
2. Peri, F., Bokel, C., Roth, S. (1999) Local Gurken signaling and dynamic MAPK activation during Drosophila oogenesis. Mech Dev 81, 75-88.
3. Peri, F., Roth, S. (2000) Combined activities of Gurken and decapentaplegic specify dorsal chorion structures of the Drosophila egg. Development 127, 841-850.
4. Riechmann, V., Ephrussi, A. (2001) Axis formation during Drosophila oogenesis. Curr Opin Genet Dev 11, 374-383.
5. Gerhart, J. (1999) 1998 Warkany lecture: signaling pathways in development. Teratology 60, 226-239.
6. Affolter, M., Mann, R. (2001) Development. Legs, eyes, or wings-selectors and signals make the difference. Science 292, 1080-1081.
7. Wodarz, A., Nusse, R. (1998) Mechanisms of Wnt signaling in development. Annu Rev Cell Dev Biol 14, 59-88.
8. Hulskamp, M., Pfeifle, C., Tautz, D. (1990) A morphogenetic gradient of hunchback protein organizes the expression of the gap genes Kruppel and knirps in the early Drosophila embryo. Nature 346, 577-580.
9. Irish, V., Lehmann, R., Akam, M. (1989) The Drosophila posterior-group gene nanos functions by repressing hunchback activity. Nature 338, 646-648.
10. Sanson, B. (2001) Generating patterns from fields of cells. Examples from Drosophila segmentation. EMBO Rep 2, 1083-1088.
11. DiNardo, S., Sher, E., Heemskerk-Jongens, J., et al. (1988) Two-tiered regulation of spatially patterned engrailed gene expression during Drosophila embryogenesis. Nature 332, 604-609.
12. Lee, J. J., von Kessler, D.P., Parks, S., et al. (1992) Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog. Cell 71, 33-50.
13. Muller, H., Samanta, R., Wieschaus, E. (1999) Wingless signaling in the Drosophila embryo: zygotic requirements and the role of the frizzled genes. Development 126, 577-586.
14. Lessing, D., Nusse, R. (1998) Expression of wingless in the Drosophila embryo: a conserved cis-acting element lacking conserved Ci-binding sites is required for patched-mediated repression. Development 125, 1469-1476.
15. DiNardo, S., Heemskerk, J., Dougan, S., et al. (1994) The making of a maggot: patterning the Drosophila embryonic epidermis. Curr Opin Genet Dev 4, 529-534.
16. van den Heuvel, M., Nusse, R., Johnston, P., et al. (1989) Distribution of the wingless gene product in Drosophila embryos: a protein involved in cell-cell communication. Cell 59, 739-749.
17. Ingham, P.W., Hidalgo, A. (1993) Regulation of wingless transcription in the Drosophila embryo. Development 117, 283-291.
18. Li, X., Noll, M. (1993) Role of the gooseberry gene in Drosophila embryos: maintenance of wingless expression by a wingless - gooseberry autoregulatory loop. Embo J 12, 4499-4509.
19. Alexandre, C., Lecourtois, M., Vincent, J. (1999) Wingless and Hedgehog pattern Drosophila denticle belts by regulating the production of short-range signals. Development 126, 5689-5698.
20. Lawrence, P. A., Sanson, B., Vincent, J. P. (1996) Compartments, wingless and engrailed: patterning the ventral epidermis of Drosophila embryos. Development 122, 4095-4103.
21. Sampedro, J., Johnston, P., Lawrence, P. A. (1993) A role for wingless in the segmental gradient of Drosophila? Development 117, 677-687.
22. Sanson, B., Alexandre, C., Fascetti, N., et al. (1999) Engrailed and hedgehog make the range of Wingless asymmetric in Drosophila embryos. Cell 98, 207-216.
23. Payre, F., A. Vincent, and S. Carreno, (1999) ovo/svb integrates Wingless and DER pathways to control epidermis differentiation. Nature 400, 271-275.
24. Howes, R., Bray, S. (2000) Pattern formation: Wingless on the move. Curr Biol 10, R222-R226.
25. Ganguly, A., Jiang, J., Ip, Y. T. (2005) Drosophila WntD is a target and an inhibitor of the Dorsal/Twist/Snail network in the gastrulating embryo. Development 132, 3419-3429.
26. Gordon, M. D., Dionne, M. S., Schneider, D. S., et al. (2005) WntD is a feedback inhibitor of Dorsal/NF-kappaB in Drosophila development and immunity. Nature 437, 746-749.
27. Ng, M., Diaz-Benjumea, F. J., Cohen, S. M. (1995) Nubbin encodes a POU-domain protein required for proximal-distal patterning in the Drosophila wing. Development 121, 589-599.
28. Rodriguez Ddel, A., Terriente, J., Galindo, M. I., et al. (2002) Different mechanisms initiate and maintain wingless expression in the Drosophila wing hinge. Development 129, 3995-4004.
29. Couso, J. P., Bate, M., Martinez-Arias, A. (1993) A wingless-dependent polar coordinate system in Drosophila imaginal discs. Science 259, 484-489.
30. Han, C., Yan, D., Belenkaya, T. Y., et al. (2005) Drosophila glypicans Dally and Dally-like shape the extracellular Wingless morphogen gradient in the wing disc. Development 132, 667-679.
31. Belenkaya, T. Y., Han, C., Yan, D., et al. (2004) Drosophila Dpp morphogen movement is independent of dynamin-mediated endocytosis but regulated by the glypican members of heparan sulfate proteoglycans. Cell 119, 231-244.
32. Diaz-Benjumea, F.J., Cohen, S. M. (1995) Serrate signals through Notch to establish a Wingless-dependent organizer at the dorsal/ventral compartment boundary of the Drosophila wing. Development 121, 4215-4225.
33. O'Brochta, D. A., Bryant, P. J. (1985) A zone of non-proliferating cells at a lineage restriction boundary in Drosophila. Nature 313, 138-141.
34. Johnston, L. A., Edgar, B. A. (1998) Wingless and Notch regulate cell-cycle arrest in the developing Drosophila wing. Nature 394, 82-84.
35. Duronio, R. J., O'Farrell, P. H., Xie, J. E., et al. (1995) The transcription factor E2F is required for S phase during Drosophila embryogenesis. Genes Dev 9, 1445-1455.
36. Neumann, C. J., Cohen, S. M. (1996) A hierarchy of cross-regulation involving Notch, wingless, vestigial and cut organizes the dorsal/ventral axis of the Drosophila wing. Development 122, 3477-3485.
37. Jaiswal, M., Agrawal, N., Sinha, P. (2006) Fat and Wingless signaling oppositely regulate epithelial cell-cell adhesion and distal wing development in Drosophila. Development 133, 925-935.
38. Fanto, M. McNeill, H. (2004) Planar polarity from flies to vertebrates. J Cell Sci 117, 527-533.
39. Colosimo, P. F., Tolwinski, N. S. (2006) Wnt, Hedgehog and junctional Armadillo/beta-catenin establish planar polarity in the Drosophila embryo. PLoS ONE 1, e9.
40. Voas, M. G., Rebay, I. (2004) Signal integration during development: insights from the Drosophila eye. Dev Dyn 229, 162-175.
41. Haynie, J. L., Bryant, P. J. (1986) Development of the eye-antenna imaginal disc and morphogenesis of the adult head in Drosophila melanogaster. J Exp Zool 237, 293-308.
42. Curtiss, J., Mlodzik, M. (2000) Morphogenetic furrow initiation and progression during eye development in Drosophila: the roles of decapentaplegic, hedgehog and eyes absent. Development 127, 1325-1336.
43. Halder, G., Callaerts, P., Flister, S., et al. (1998) Eyeless initiates the expression of both sine oculis and eyes absent during Drosophila compound eye development. Development 125, 2181-2191.
44. Halder, G., Callaerts, P., Gehring, W. J. (1995) Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila. Science 267, 1788-1792.
45. Pignoni, F., Zipursky, S. L. (1997) Induction of Drosophila eye development by decapentaplegic. Development 124, 271-278.
46. Lee, J. D., Treisman, J. E. (2001) The role of Wingless signaling in establishing the anteroposterior and dorsoventral axes of the eye disc. Development 128, 1519-1529.
47. Baonza, A., Freeman, M. (2002) Control of Drosophila eye specification by Wingless signalling. Development 129, 5313-5322.
48. Treisman, J. E., Rubin, G. M. (1995) wingless inhibits morphogenetic furrow movement in the Drosophila eye disc. Development 121, 3519-3527.
49. Heberlein, U., Borod, E. R., Chanut, F. A. (1998) Dorsoventral patterning in the Drosophila retina by wingless. Development 125, 567-577.
50. Maurel-Zaffran, C., Treisman, J. E. (2000) pannier acts upstream of wingless to direct dorsal eye disc development in Drosophila. Development 127, 1007-1016.
51. Cavodeassi, F., Diez Del Corral, R., Campuzano, S., et al. (1999) Compartments and organising boundaries in the Drosophila eye: the role of the homeodomain Iroquois proteins. Development 126, 4933-4942.
52. Zeidler, M. P., Perrimon, N. Strutt, D. I. (1999) Polarity determination in the Drosophila eye: a novel role for unpaired and JAK/STAT signaling. Genes Dev 13, 1342-1353.
53. Yang, C. H., Simon, M. A., McNeill, H. (1999) mirror controls planar polarity and equator formation through repression of fringe expression and through control of cell affinities. Development 126, 5857-5866.
54. Ekas, L. A., Baeg, G. H., Flaherty, M. S., et al. (2006) JAK/STAT signaling promotes regional specification by negatively regulating wingless expression in Drosophila. Development 133, 4721-4729.