Stabilization of torpedo californica acetylcholinesterase by reversible inhibitors

Biochemistry

Volumn 48, Issue 3, 2009, Pages 563-574

  Weiner, Lev ^a   Shnyrov, Valery L ^b   Konstantinovskii, Leonid ^a   Roth, Esther ^a   Ashani, Yacov ^a   Silman, Israel ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

3-D STRUCTURES; ACETYLCHOLINESTERASE; ACTIVE SITES; ANIONIC SITES; CHEMICAL CHAPERONES; CYSTEINE RESIDUES; DENATURING AGENTS; DIVALENT CATIONS; EXPERIMENTAL SYSTEMS; LARGE SURFACE AREAS; LOW MOLECULAR WEIGHTS; NATIVE FORMS; NATIVE STATE; PERIPHERAL ANIONIC SITES; PROPIDIUM; SITE-DIRECTED INHIBITORS; SPECTROSCOPIC TECHNIQUES; STABILIZING EFFECTS; SUB-DOMAINS; THERMAL INACTIVATIONS; THERMAL STABILITIES; THERMODYNAMIC PARAMETERS;

ABERRATIONS; BINDING ENERGY; CHEMICAL MODIFICATION; DIFFERENTIAL SCANNING CALORIMETRY; DYES; ENZYMES; LIGANDS; LITHIUM BATTERIES; STABILIZATION; SYSTEM STABILITY; THERMODYNAMIC STABILITY; TORPEDOES;

BINDING SITES;

1,5 BIS(4 ALLYLDIMETHYLAMMONIUMPHENYL)PENTAN 3 ONE DIBROMIDE; ACETYLCHOLINESTERASE; CHAPERONE; CHOLINESTERASE INHIBITOR; CYSTEINE; DECAMETHONIUM; EDROPHONIUM; FASCICLIN II; PROPIDIUM IODIDE; TACRINE; TUBOCURARINE CHLORIDE; DISULFIDE; FASCICULIN; GUANIDINE; LIGAND; SNAKE VENOM;

ARTICLE; BINDING SITE; CHEMICAL MODIFICATION; DIFFERENTIAL SCANNING CALORIMETRY; ENZYME ACTIVE SITE; ENZYME DENATURATION; ENZYME INACTIVATION; ENZYME STABILITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; THERMODYNAMICS; THERMOSTABILITY; TORPEDO CALIFORNICA; ANIMAL; CALORIMETRY; DRUG EFFECT; ENTROPY; ENZYME ACTIVATION; HUMAN; KINETICS; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN DENATURATION; PROTEIN SECONDARY STRUCTURE; SPIN LABELING; TEMPERATURE; TORPEDO;

TORPEDO CALIFORNICA;

ACETYLCHOLINESTERASE; ANIMALS; BENZENAMINIUM, 4,4'-(3-OXO-1,5-PENTANEDIYL)BIS(N,N-DIMETHYL-N-2-PROPENYL-), DIBROMIDE; CALORIMETRY; CHOLINESTERASE INHIBITORS; DECAMETHONIUM COMPOUNDS; DISULFIDES; ELAPID VENOMS; ENTROPY; ENZYME ACTIVATION; ENZYME STABILITY; GUANIDINE; HUMANS; KINETICS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; SPIN LABELS; TACRINE; TEMPERATURE; TORPEDO;

EID: 59249087074     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi801196y     Document Type: Article

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