1H NMR relaxation investigation of acetylcholinesterase inhibitors from huperzine A and derivative

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 6, 2004, Pages 1585-1588

  Li, Yiming ^a   Li, Qian ^b   Sun, Manchi ^b   Song, Guoqiang ^a   Jiang, Shanhao ^a   Zhu, Dayuan ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

Author keywords

Acetylcholinesterase; Huperzine A; NMR; Relaxation

Indexed keywords

ACETYLCHOLINE DERIVATIVE; CHOLINESTERASE INHIBITOR; HUPERZINE A; LIGAND; PROTEIN DERIVATIVE; PROTON; HYDROGEN; SESQUITERPENE;

ANALYTIC METHOD; ARTICLE; BINDING AFFINITY; BINDING SITE; CORRELATION ANALYSIS; DIPOLE; DRUG SCREENING; DRUG SELECTIVITY; MATHEMATICAL COMPUTING; MOLECULAR INTERACTION; MOLECULAR MECHANICS; PROTON NUCLEAR MAGNETIC RESONANCE; ANIMAL; CHEMISTRY; COMPARATIVE STUDY; HUPERZIA; ISOLATION AND PURIFICATION; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; TORPEDO;

TORPEDINIFORMES;

ANIMALS; CHOLINESTERASE INHIBITORS; HUPERZIA; HYDROGEN; MAGNETIC RESONANCE SPECTROSCOPY; SESQUITERPENES; TORPEDO;

EID: 1542374726     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2003.12.055     Document Type: Article

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