Derivation of a compartmental model for quantifying64Cu-DOTA-RGD kinetics in tumor-bearing mice

Journal of Nuclear Medicine

Volumn 50, Issue 2, 2009, Pages 250-258

  Ferl, Gregory Z ^a   Dumont, Rebecca A ^a   Hildebrandt, Isabel J ^a   Armijo, Amanda ^a   Haubner, Roland ^b   Reischl, Gerald ^c   Su, Helen ^a   Weber, Wolfgang A ^d   Huang, Sung Cheng ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d UNIVERSITY OF FREIBURG   (Germany)

Author keywords

v 3 integrin; Compartmental model; Pharmacokinetics; RGD peptide; Small animal PET

Indexed keywords

1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID ARGINYLGLYCYLASPARTIC ACID CU 64; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; COMPARTMENT MODEL; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG UPTAKE; MALE; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SCID MOUSE; TUMOR;

ANIMALS; CELL LINE, TUMOR; COPPER RADIOISOTOPES; HETEROCYCLIC COMPOUNDS, 1-RING; HUMANS; INTEGRIN ALPHAVBETA3; MALE; MICE; MICE, SCID; MODELS, BIOLOGICAL; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; OLIGOPEPTIDES; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 59249086628     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.108.054049     Document Type: Article

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