Serum levels of antibodies to Chlamydia pneumoniae and human HSP60 in giant cell arteritis patients

Clinical and Experimental Rheumatology

Volumn 26, Issue 6, 2008, Pages 1107-1110

  López Hoyos, Marcos ^a   Álvarez, Lorena ^b   Soto, María Ruiz ^b   Blanco, Ricardo ^b   Bartolomé, María José ^a   Martínez Taboada, Victor M ^b  

^a UNIVERSITY OF CANTABRIA   (Spain)

^b HOSPITAL UNIVERSITARIO MARQUÉS DE VALDECILLA   (Spain)

Author keywords

Antibodies; Chlamydia pneumoniae; Giant cell arteritis; HSP60; Polymyalgia rheumatica

Indexed keywords

CORTICOSTEROID; HEAT SHOCK PROTEIN 60; IMMUNOGLOBULIN G ANTIBODY; PREDNISONE; PROTEIN ANTIBODY;

AGED; ANTIBODY BLOOD LEVEL; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; CHLAMYDIASIS; CHLAMYDOPHILA PNEUMONIAE; CONTROLLED STUDY; CORTICOSTEROID THERAPY; DRUG DOSE REDUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GIANT CELL ARTERITIS; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; QUANTITATIVE ANALYSIS; REMISSION; RHEUMATIC POLYMYALGIA;

AGED; ANTIBODIES, BACTERIAL; AUTOANTIBODIES; CHAPERONIN 60; CHLAMYDOPHILA INFECTIONS; CHLAMYDOPHILA PNEUMONIAE; FEMALE; GIANT CELL ARTERITIS; HUMANS; IMMUNOGLOBULIN G; MALE; POLYMYALGIA RHEUMATICA; REMISSION INDUCTION; RISK FACTORS; SEROEPIDEMIOLOGIC STUDIES; STEROIDS;

EID: 59149096587     PISSN: 0392856X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. SALVARANI C, CANTINI F, BOIARDI L: Polymyalgia rheumatica and giant-cell arteritis. N Engl J Med. 2002; 347: 261-71.
2. DASGUPTA B, HASSAN N: British Society for Rheumatology Guidelines Group. Giant cell arteritis: Recent advances and guidelines for management. Clin Exp Rheumatol 2007; 25 (Suppl. 44): S62-5.
3. WARRINGTON KJ, MATTESON EL: Management guidelines and outcome measures in giant cells arteritis (GCA). Clin Exp Rheumatol 2007; 25 (Suppl. 47): S137-41.
4. WEYAND CM, GORONZY JJ: Giant-cell arteritis and polymyalgia rheumatica. Ann Intern Med 2003; 139: 505-15.
5. RIMENTI G, BLASI F, COSENTINI R et al.: Temporal arteritis associated with Chlamydia pneumoniae DNA detected in an artery specimen. J Rheumatol 2000; 27: 2718-20.
6. WAGNER AD, GERARD HC, FRESEMANN T et al.: Detection of Chlamydia pneumoniae in giant cell vasculitis and correlation with the topographic arrangement of tissue-infiltrating dendritic cells. Arthritis Rheum 2000; 43: 1543-51.
7. REGAN MJ, WOOD BJ, HSIEH YH et al.: Temporal arteritis and Chlamydia pneumoniae. Failure to detect the organism by polymerase chain reaction in ninety cases and ninety controls. Arthritis Rheum 2002; 46: 1056-60.
8. HELWEG-LARSEN J, TARP B, OBEL N et al.: No evidence of parvovirus B19, Chlamydia pneumoniae or human herpes virus infection in temporal artery biopsies in patients with giant cell arteritis. Rheumatology (Oxford) 2002; 41: 445-9.
9. SAIKKU P: Chlamydia pneumoniae in atherosclerosis. J Intern Med 2000; 247: 391-6.
10. DUHAUT P, PINEDE L, DEMOLONBE-RAGUE S et al.: Giant cell arteritis and cardiovascular risk factors. A multicenter, prospective case-control study. Arthritis Rheum 1998; 41: 1960-5.
11. AYADA K, YOKOTA K, KOBAYASHI K et al.: Chronic infections and atherosclerosis. Ann N Y Acad Sci 2007; 1108: 594-602.
12. WICK G, PERSCHINKA H, MILLONIG G: Atherosclerosis as an autoimmune disease: An update. Trends Immunol 2001; 22: 665-9.
13. VALASSINA M, MIGLIORINI L, SANSONI A et al.: Search for Chlamydia pneumoniae genes and their expression in atherosclerotic plaques of carotid arteries. J Med Microbiol 2001; 50: 228-32.
14. CHAUHAN SK, SINGH M, NITYANAND S: Reactivity of gamma/delta T cells to human 60-kd heat-shock protein and their cytotoxicity to aortic endothelial cells in Takayasu arteritis. Arthritis Rheum 2007; 56: 2798-802.
15. JAMIN C, DUGUÉ C, ALARD JE et al.: Induction of endothelial cell apoptosis by the finding of anti-endothelial cell antibodies to Hsp60 in vasculitis-associated systemic autoimmune diseases. Arthritis Rheum 2005; 52: 4028-38.
16. YOKOTA S, MINOTA S, FUJII N: Anti-HSP auto-antibodies enhance HSP-induced proinflammatory cytokine production in human monocytic cells via Toll-like receptors. Int Immunol 2006; 18: 573-80.
17. MANDAL K, FOTEINOS G, JAHANGIRI M et al.: Role of antiheat shock protein 60 autoantibodies in atherosclerosis. Lupus 2005; 14: 742-6.
18. BIASUCCI LM, LIUZZO G, CIERVO A et al.: Antibody response to chlamydial heat shock protein 60 is strongly associated with acute coronary syndromes. Circulation 2003; 107: 3015-7.
19. HELTAI K, KIS Z, BURIAN K et al.: Elevated antibody levels against Chlamydia pneumoniae, human HSP60 and mycobacterial HSP65 are independent risk factors in myocardial infarction and ischaemic heart disease. Atherosclerosis 2004; 173: 339-46.
20. HOSHIDA S, NISHINO M, TANOUCHI J et al.: Acute Chlamydia pneumoniae infection with heat-shock-protein-60-related response in patients with acute coronary syndrome. Atherosclerosis 2005; 183: 109-12.
21. MARTINEZ-TABOADA VM, BARTOLOME MJ, FERNANDEZ-GONZALEZ MD et al.: Homocysteine levels in polymyalgia rheumatica and giant cell arteritis: influence of corticosteroid therapy. Rheumatology (Oxford) 2003; 42: 1055-61.